Citations for
1OTUD5, STING1
OTUD5 promotes innate antiviral and antitumor immunity through deubiquitinating and stabilizing STING
Guo Y, Jiang F, Kong L, Wu H, Zhang H, Chen X, Zhao J, Cai B, Li Y, Ma C, Yi F, Zhang L, Liu B, Zheng Y, Zhang L, Gao C
Cell Mol Immunol. Aug;18(8):1945-1955. doi: 10.1038/s41423-020-00531-5. Epub 2020 Sep 2. 2021
2MTOR, OTUD5
Deubiquitinase OTUD5 is a positive regulator of mTORC1 and mTORC2 signaling pathways
Cho JH, Kim K, Kim SA, Park S, Park BO, Kim JH, Kim SY, Kwon MJ, Han MH, Lee SB, Park BC, Park SG, Kim JH, Kim S.
Cell Death Differ. Mar;28(3):900-914. doi: 10.1038/s41418-020-00649-z. Epub 2020 Oct 27. 2021
3MCAND, OTUD5
OTUD5 Variants Associated With X-Linked Intellectual Disability and Congenital Malformation.
Saida K, Fukuda T, Scott DA, Sengoku T, Ogata K, Nicosia A, Hernandez-Garcia A, Lalani SR, Azamian MS, Streff H, Liu P, Dai H, Mizuguchi T, Miyatake S, Asahina M, Ogata T, Miyake N, Matsumoto N.
Front Cell Dev Biol. Mar 3;9:631428. doi: 10.3389/fcell.2021.631428. 2021
4MCAND, OTUD5
Linkage-specific deubiquitylation by OTUD5 defines an embryonic pathway intolerant to genomic variation
Beck DB, Basar MA, Asmar AJ, Thompson JJ, Oda H, Uehara DT, Saida K, Pajusalu S, Talvik I, D'Souza P, Bodurtha J, Mu W, Barañano KW, Miyake N, Wang R, Kempers M, Tamada T, Nishimura Y, Okada S, Kosho T, Dale R, Mitra A, Macnamara E; Undiagnosed Diseases Network, Matsumoto N, Inazawa J, Walkiewicz M, Õunap K, Tifft CJ, Aksentijevich I, Kastner DL, Rocha PP, Werner A.
Sci Adv. Jan 20;7(4):eabe2116. doi: 10.1126/sciadv.abe2116 2021
5MCAND, OTUD5
An X-linked syndrome with severe neurodevelopmental delay, hydrocephalus, and early lethality caused by a missense variation in the OTUD5 gene.
Tripolszki K, Sasaki E, Hotakainen R, Kassim AH, Pereira C, Rolfs A, Bauer P, Reardon W, Bertoli-Avella AM.
Clin Genet. Feb;99(2):303-308. doi: 10.1111/cge.13873. Epub 2020 Nov 9 2021
6OTUD5
Phosphorylation-dependent activity of the deubiquitinase DUBA.
Huang OW, Ma X, Yin J, Flinders J, Maurer T, Kayagaki N, Phung Q, Bosanac I, Arnott D, Dixit VM, Hymowitz SG, Starovasnik MA, Cochran AG.
Nat Struct Mol Biol. Jan 15;19(2):171-5. doi: 10.1038/nsmb.2206. 2021
7OTUD5, TRIM25
OTUD5 cooperates with TRIM25 in transcriptional regulation and tumor progression via deubiquitination activity
Li F, Sun Q, Liu K, Zhang L, Lin N, You K, Liu M, Kon N, Tian F, Mao Z, Li T, Tong T, Qin J, Gu W, Li D, Zhao W.
Nat Commun. Aug 21;11(1):4184. doi: 10.1038/s41467-020-17926-7. 2020
8OTUD5, UBR5
The OTUD5-UBR5 complex regulates FACT-mediated transcription at damaged chromatin.
de Vivo A, Sanchez A, Yegres J, Kim J, Emly S, Kee Y.
Nucleic Acids Res. Jan 25;47(2):729-746. doi: 10.1093/nar/gky1219. 2019
9OTUD5, PDCD5
Deubiquitinase OTUD5 mediates the sequential activation of PDCD5 and p53 in response to genotoxic stress
Park SY, Choi HK, Choi Y, Kwak S, Choi KC, Yoon HG.
Cancer Lett. Feb 1;357(1):419-427. doi: 10.1016/j.canlet.2014.12.005. Epub 2014 Dec 8. 2015
10OTUD5, TP53
OTUD5 regulates p53 stability by deubiquitinating p53
Luo J, Lu Z, Lu X, Chen L, Cao J, Zhang S, Ling Y, Zhou X.
PLoS One. Oct 15;8(10):e77682. doi: 10.1371/journal.pone.0077682. 2013
11OTUD5
DUBA: a deubiquitinase that regulates type I interferon production.
Kayagaki N, Phung Q, Chan S, Chaudhari R, Quan C, O'Rourke KM, Eby M, Pietras E, Cheng G, Bazan JF, Zhang Z, Arnott D, Dixit VM.
Science. Dec 7;318(5856):1628-32. doi: 10.1126/science.1145918. Epub 2007 Nov 8 2007