1 | KRT80, OTUB2
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| OTUB2 regulates KRT80 stability via deubiquitination and promotes tumour proliferation in gastric cancer
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| Ouyang S, Zeng Z, Liu Z, Zhang Z, Sun J, Wang X, Ma M, Ye X, Yu J, Kang W.
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| Cell Death Discov. Feb 2;8(1):45. doi: 10.1038/s41420-022-00839-3. Erratum in: Cell Death Discov. 2022 Apr 19;8(1):211 2022
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2 | KDM1A, OTUB2
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| OTUB2 Facilitates Tumorigenesis of Gastric Cancer Through Promoting KDM1A-Mediated Stem Cell-Like Properties
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| Liu G, Guo W, Qin J, Lin Z.
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| Front Oncol. Sep 27;11:711735. doi: 10.3389/fonc.2021.711735 2021
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3 | OTUB1, OTUB2
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| The functions and regulation of Otubains in protein homeostasis and diseases.
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| Zhu Q, Fu Y, Li L, Liu CH, Zhang L.
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| Ageing Res Rev. May;67:101303. doi: 10.1016/j.arr.2021.101303. Epub 2021 Feb 17. 2021
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4 | OTUB1, OTUB2
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| Activation and selectivity of OTUB-1 and OTUB-2 deubiquitinylases.
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| Sivakumar D, Kumar V, Naumann M, Stein M.
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| J Biol Chem. May 15;295(20):6972-6982. doi: 10.1074/jbc.RA120.013073. Epub 2020 Apr 7. 2020
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5 | OTUB2
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| OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ
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| Zhang Z, Du J, Wang S, Shao L, Jin K, Li F, Wei B, Ding W, Fu P, van Dam H, Wang A, Jin J, Ding C, Yang B, Zheng M, Feng XH, Guan KL, Zhang L.
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| Mol Cell. Jan 3;73(1):7-21.e7. doi: 10.1016/j.molcel.2018.10.030. Epub 2018 Nov 21. 2019
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6 | GLI2, OTUB2
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| Regulation of Gli2 stability by deubiquitinase OTUB2
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| Li XY, Mao XF, Tang XQ, Han QQ, Jiang LX, Qiu YM, Dai J, Wang YX.
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| Biochem Biophys Res Commun. Oct 20;505(1):113-118. doi: 10.1016/j.bbrc.2018.09.071. Epub 2018 Sep 19. 2018
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7 | OTUB2
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| Fine-tuning of DNA damage-dependent ubiquitination by OTUB2 supports the DNA repair pathway choice
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| Kato K, Nakajima K, Ui A, Muto-Terao Y, Ogiwara H, Nakada S.
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| Mol Cell. Feb 20;53(4):617-30. doi: 10.1016/j.molcel.2014.01.030. 2014
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8 | OTUB1, OTUB2, TRAF3, TRAF6
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| Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6.
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| Li S, Zheng H, Mao AP, Zhong B, Li Y, Liu Y, Gao Y, Ran Y, Tien P, Shu HB.
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| J Biol Chem 285(7):4291-7. Epub 2009 Dec 7.
2010
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9 | OTUB1, OTUB2
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| Structural basis and specificity of human otubain 1-mediated deubiquitination.
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| Edelmann MJ, Iphöfer A, Akutsu M, Altun M, di Gleria K, Kramer HB, Fiebiger E, Dhe-Paganon S, Kessler BM.
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| Biochem J 418(2):379-90.
2009
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10 | SERPINA1, SERPINA2, SERPINA3, SERPINA4, SERPINA5, SERPINA6, SERPINA9, SERPINA10, SERPINA11, SERPINA12, SERPINA13, OTUB2, RPSAP4
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| Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1.
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| Namciu SJ, Friedman RD, Marsden MD, Sarausad LM, Jasoni CL, Fournier RE.
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| Mamm Genome 15(3):162-78. 2004
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11 | OTUB2
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| Crystal structure of human otubain 2.
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| Nanao MH, Tcherniuk SO, Chroboczek J, Dideberg O, Dessen A, Balakirev MY.
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| EMBO Rep 5(8):783-8. Epub 2004 Jul 16.PMID: 15258613 2004
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12 | OTUB1, OTUB2
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| Otubains: a new family of cysteine proteases in the ubiquitin pathway.
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| Balakirev MY, Tcherniuk SO, Jaquinod M, Chroboczek J.
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| EMBO Rep 4(5):517-22. 2003
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