Citations for
1OTUB1, UBE2D1
Monoubiquitination Is Critical for Otub1 to Suppress UbcH5 and Stabilize p53.
Li Y, Sun XX, Elferich J, Shinde U, David LL, Dai MS.
J Biol Chem Biol Chem. 2014 Jan 8. [Epub ahead of print] 2014
2NMRAL1, OTUB1, TRAF3
HSCARG negatively regulates the cellular antiviral RIG-I like receptor signaling pathway by inhibiting TRAF3 ubiquitination via recruiting OTUB1.
Peng Y, Xu R, Zheng X.
PLoS Pathog 10(4):e1004041. doi: 10.1371/journal.ppat.1004041. eCollection 2014 Apr. 2014
3OTUB1, UBE2D1, UBE2N
E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1.
Wiener R, DiBello AT, Lombardi PM, Guzzo CM, Zhang X, Matunis MJ, Wolberger C.
Nat Struct Mol Biol 20(9):1033-9. doi: 10.1038/nsmb.2655. Epub 2013 Aug 18. 2013
4BIRC2, OTUB1
OTUB1 modulates c-IAP1 stability to regulate signalling pathways.
Goncharov T, Niessen K, de Almagro MC, Izrael-Tomasevic A, Fedorova AV, Varfolomeev E, Arnott D, Deshayes K, Kirkpatrick DS, Vucic D.
EMBO J 32(8):1103-14. doi: 10.1038/emboj.2013.62. Epub 2013 Mar 22. 2013
5OTUB1, UBE2N, UBE2V1, UBE2V2
Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13.
Sato Y, Yamagata A, Goto-Ito S, Kubota K, Miyamoto R, Nakada S, Fukai S.
J Biol Chem 287(31):25860-8. doi: 10.1074/jbc.M112.364752. Epub 2012 Jun 7. 2012
6OTUB1, UBE2N, UBE2V1
The mechanism of OTUB1-mediated inhibition of ubiquitination.
Wiener R, Zhang X, Wang T, Wolberger C.
Nature 483(7391):618-22. doi: 10.1038/nature10911. 2012
7OTUB1
OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function.
Juang YC, Landry MC, Sanches M, Vittal V, Leung CC, Ceccarelli DF, Mateo AR, Pruneda JN, Mao DY, Szilard RK, Orlicky S, Munro M, Brzovic PS, Klevit RE, Sicheri F, Durocher D.
Mol Cell 45(3):384-97. doi: 10.1016/j.molcel.2012.01.011. Erratum in: Mol Cell. 2012 May 25;46(4):549. 2012
8OTUB1
OTUB1 overexpression in mesangial cells is a novel regulator in the pathogenesis of glomerulonephritis through the decrease of DCN level.
Zhang Y, Hu R, Wu H, Jiang W, Sun Y, Wang Y, Song Y, Jin T, Zhang H, Mao X, Zhao Z, Zhang Z.
PLoS One 7(1):e29654. doi: 10.1371/journal.pone.0029654. Epub 2012 Jan 18. 2012
9OTUB1, OTUB2, TRAF3, TRAF6
Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6.
Li S, Zheng H, Mao AP, Zhong B, Li Y, Liu Y, Gao Y, Ran Y, Tien P, Shu HB.
J Biol Chem 285(7):4291-7. Epub 2009 Dec 7. 2010
10OTUB1
Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1.
Nakada S, Tai I, Panier S, Al-Hakim A, Iemura S, Juang YC, O'Donnell L, Kumakubo A, Munro M, Sicheri F, Gingras AC, Natsume T, Suda T, Durocher D.
Nature 466(7309):941-6. 2010
11OTUB1
When cleavage is not attractive: Non-catalytic inhibition of ubiquitin chains at DNA double-strand breaks by OTUB1.
Blackford AN, Stewart GS.
DNA Repair (Amst) NA Repair (Amst). 2010 Dec 2. [Epub ahead of print]PMID: 21130715 2010
12OTUB1, RNF168, UBE2N
Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1.
Nakada S, Tai I, Panier S, Al-Hakim A, Iemura S, Juang YC, O'Donnell L, Kumakubo A, Munro M, Sicheri F, Gingras AC, Natsume T, Suda T, Durocher D.
Nature 466(7309):941-6. doi: 10.1038/nature09297. 2010
13OTUB1, OTUB2
Structural basis and specificity of human otubain 1-mediated deubiquitination.
Edelmann MJ, Iphöfer A, Akutsu M, Altun M, di Gleria K, Kramer HB, Fiebiger E, Dhe-Paganon S, Kessler BM.
Biochem J 418(2):379-90. 2009
14OTUB1
OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity.
Stanisić V, Malovannaya A, Qin J, Lonard DM, O'Malley BW.
J Biol Chem 284(24):16135-45. Epub 2009 Apr 21.PMID: 19383985 2009
15OTUB1
Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein.
Messick TE, Russell NS, Iwata AJ, Sarachan KL, Shiekhattar R, Shanks JR, Reyes-Turcu FE, Wilkinson KD, Marmorstein R.
J Biol Chem 283(16):11038-49. Epub 2008 Feb 12.PMID: 18270205 2008
16OTUB1, RNF128
Two isoforms of otubain 1 regulate T cell anergy via GRAIL.
Soares L, Seroogy C, Skrenta H, Anandasabapathy N, Lovelace P, Chung CD, Engleman E, Fathman CG.
Nat Immunol 5(1):45-54. Epub 2003 Dec 7.PMID: 14661020 2004
17OTUB1, OTUB2
Otubains: a new family of cysteine proteases in the ubiquitin pathway.
Balakirev MY, Tcherniuk SO, Jaquinod M, Chroboczek J.
EMBO Rep 4(5):517-22. 2003