| 1 | OTOP1, OTOP2, OTOP3
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| Structural motifs for subtype-specific pH-sensitive gating of vertebrate otopetrin proton channels
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| Teng B, Kaplan JP, Liang Z, Krieger Z, Tu YH, Burendei B, Ward AB, Liman ER.
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| Elife Aug 3;11:e77946. doi: 10.7554/eLife.77946. 2022
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| 2 | OTOP1, OTOP3
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| Structures of the otopetrin proton channels Otop1 and Otop3
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| Saotome K, Teng B, Tsui CCA, Lee WH, Tu YH, Kaplan JP, Sansom MSP, Liman ER, Ward AB.
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| Nat Struct Mol Biol. Jun;26(6):518-525. doi: 10.1038/s41594-019-0235-9. Epub 2019 Jun 3. 2019
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| 3 | OTOP1, OTOP2, OTOP3
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| An evolutionarily conserved gene family encodes proton-selective ion channels.
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| Tu YH, Cooper AJ, Teng B, Chang RB, Artiga DJ, Turner HN, Mulhall EM, Ye W, Smith AD, Liman ER
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| Science. Mar 2;359(6379):1047-1050. doi: 10.1126/science.aao3264. Epub 2018 Jan 25. 2018
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| 4 | OTOP1, P2RY2
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| Missense mutations in Otopetrin 1 affect subcellular localization and inhibition of purinergic signaling in vestibular supporting cells.
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| Kim E, Hyrc KL, Speck J, Salles FT, Lundberg YW, Goldberg MP, Kachar B, Warchol ME, Ornitz DM.
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| Mol Cell Neurosci 46(3):655-61. doi: 10.1016/j.mcn.2011.01.005. Epub 2011 Jan 12.
2011
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| 5 | OTOP1, OTOP2, OTOP3
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| Lineage-specific evolution of the vertebrate Otopetrin gene family revealed by comparative genomic analyses
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| Hurle B, Marques-Bonet T, Antonacci F, Hughes I, Ryan JF; NISC Comparative Sequencing Program, Eichler EE, Ornitz DM, Green ED.
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| BMC Evol Biol. Jan 24;11:23. doi: 10.1186/1471-2148-11-23. 2011
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| 6 | OTOP1
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| Regulation of cellular calcium in vestibular supporting cells by otopetrin 1.
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| Kim E, Hyrc KL, Speck J, Lundberg YW, Salles FT, Kachar B, Goldberg MP, Warchol ME, Ornitz DM.
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| J Neurophysiol 104(6):3439-50. doi: 10.1152/jn.00525.2010. Epub 2010 Jun 16.
2010
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| 7 | OTOP1, OTOP2, OTOP3
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| Identification of the Otopetrin Domain, a conserved domain in vertebrate otopetrins and invertebrate otopetrin-like family members
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| Hughes I, Binkley J, Hurle B, Green ED; NISC Comparative Sequencing Program, Sidow A, Ornitz DM.
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| BMC Evol Biol. Feb 6;8:41. doi: 10.1186/1471-2148-8-41. 2008
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| 8 | OTOP1
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| Otopetrin 1 activation by purinergic nucleotides regulates intracellular calcium.
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| Hughes I, Saito M, Schlesinger PH, Ornitz DM.
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| Proc Natl Acad Sci U S A 104(29):12023-8. Epub 2007 Jul 2.
2007
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| 9 | OTOP1, OTOP2, OTOP3
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| Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1.
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| Hurle B, Ignatova E, Massironi SM, Mashimo T, Rios X, Thalmann I,Thalmann R, Ornitz DM.
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| Hum Mol Genet 12(7):777-89. 2003
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