1 | ORC1, ORC2, ORC3, ORC4, ORC5
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| Structure of the origin recognition complex bound to DNA replication origin.
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| Li N, Lam WH, Zhai Y, Cheng J, Cheng E, Zhao Y, Gao N, Tye BK.
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| Nature 559(7713):217-222. doi: 10.1038/s41586-018-0293-x. Epub 2018 Jul 4.
2018
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2 | KAT2A, ORC5
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| Orc5 induces large-scale chromatin decondensation in a GCN5-dependent manner.
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| Giri S, Chakraborty A, Sathyan KM, Prasanth KV, Prasanth SG.
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| J Cell Sci 129(2):417-29. doi: 10.1242/jcs.178889. Epub 2015 Dec 7.
2016
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3 | ORC1, ORC4, ORC5, oRC3
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| ORC4 surrounds extruded chromatin in female meiosis.
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| Nguyen H, Ortega MA, Ko M, Marh J, Ward WS.
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| J Cell Biochem 116(5):778-86. doi: 10.1002/jcb.25033.
2015
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4 | ORC1, ORC2, ORC3, ORC4, ORC5
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| Protein phosphatase 1 dephosphorylates Orc2.
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| Lee KY, Bae JS, Kim GS, Hwang DS.
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| Biochem Biophys Res Commun 447(3):437-40. doi: 10.1016/j.bbrc.2014.04.029. Epub 2014 Apr 13.
2014
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5 | CDC6, ORC1, ORC5, ORC6
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| Different roles of the human Orc6 protein in the replication initiation process.
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| Thomae AW, Baltin J, Pich D, Deutsch MJ, Ravasz M, Zeller K, Gossen M, Hammerschmidt W, Schepers A.
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| Cell Mol Life Sci 68(22):3741-56. doi: 10.1007/s00018-011-0675-9. Epub 2011 Apr 2.
2011
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6 | ORC2, ORC3, ORC5, ORC6
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| Origin recognition complex (ORC) mediates histone 3 lysine 4 methylation through cooperation with Spp1 in Saccharomyces cerevisiae.
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| Kan J, Zou L, Zhang J, Wu R, Wang Z, Liang C.
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| J Biol Chem 283(49):33803-7. Epub 2008 Oct 9.PMID: 18845545 2008
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7 | CDT1, ORC1, ORC2, ORC3, ORC4, ORC5, ORC6
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| Interaction between ORC and Cdt1p of Saccharomyces cerevisiae.
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| Asano T, Makise M, Takehara M, Mizushima T.
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| FEMS Yeast Res 7(8):1256-62. Epub 2007 Sep 6.PMID: 17825064 2007
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8 | ORC5
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| Nucleotide-dependent conformational changes in the DnaA-like core of the origin recognition complex.
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| Clarey MG, Erzberger JP, Grob P, Leschziner AE, Berger JM, Nogales E, Botchan M.
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| Nat Struct Mol Biol 13(8):684-90. Epub 2006 Jul 9.
2006
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9 | DNAJC2, KMT2E, LRRC17, ORC5, PSMC2, RELN, S100A11P, SRPK2
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| Candidate gene isolation and comparative analysis of a commonly deleted segment of 7q22 implicated in myeloid malignancies.
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| Kratz CP, Emerling BM, Donovan S, Laig-Webster M, Taylor BR, Thompson P, Jensen S, Banerjee A, Bonifas J, Makalowski W, Green ED, Le Beau MM, Shannon KM.
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| Genomics 77(3):171-80. 2001
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10 | ORC5, TSG7B
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| ORC5L, a new member of the human origin recognition complex, is deleted in uterine leiomyomas and malignant myeloid diseases.
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| Quintana DG, Thome KC, Hou ZH, Ligon AH, Morton CC, Dutta A.
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| J Biol Chem 273(42):27137-45. 1998
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11 | ORC3, ORC4, ORC5
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| The Orc4p and Orc5p subunits of the Xenopus and human origin recognition complex are related to Orc1p and Cdc6p.
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| Tugal T, Zou-Yang XH, Gavin K, Pappin D, Canas B, Kobayashi R, Hunt T, Stillman B.
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| J Biol Chem 273(49):32421-9. 1998
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12 | ORC5
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| Isolation of human and fission yeast homologues of the budding yeast origin recognition complex subunit ORC5 : human homologue (ORC5L) maps to 7q22.
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| Ishiai M, Dean FB, Okumura K, Abe M, Moon KY, Amin AA, Kagotani K, Taguchi H, Murakami Y, Hanaoka F, O'Donnell M, Hurwitz J, Eki T.
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| Genomics 46(2):294-8. 1997
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