1 | ORC1, ORC2, ORC3, ORC4, ORC5
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| Structure of the origin recognition complex bound to DNA replication origin.
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| Li N, Lam WH, Zhai Y, Cheng J, Cheng E, Zhao Y, Gao N, Tye BK.
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| Nature 559(7713):217-222. doi: 10.1038/s41586-018-0293-x. Epub 2018 Jul 4.
2018
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2 | ORC1, ORC4, ORC5, oRC3
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| ORC4 surrounds extruded chromatin in female meiosis.
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| Nguyen H, Ortega MA, Ko M, Marh J, Ward WS.
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| J Cell Biochem 116(5):778-86. doi: 10.1002/jcb.25033.
2015
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3 | ORC1, ORC2, ORC3, ORC4, ORC5
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| Protein phosphatase 1 dephosphorylates Orc2.
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| Lee KY, Bae JS, Kim GS, Hwang DS.
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| Biochem Biophys Res Commun 447(3):437-40. doi: 10.1016/j.bbrc.2014.04.029. Epub 2014 Apr 13.
2014
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4 | CBX5, ORC1, ORC2, ORC3
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| Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization.
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| Prasanth SG, Shen Z, Prasanth KV, Stillman B.
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| Proc Natl Acad Sci U S A 107(34):15093-8. Epub 2010 Aug 5.PMID: 20689044 2010
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5 | ORC1, ORC2, ORC3
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| Binding of Drosophila ORC proteins to anaphase chromosomes requires cessation of mitotic cyclin-dependent kinase activity.
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| Baldinger T, Gossen M.
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| Mol Cell Biol 29(1):140-9. Epub 2008 Oct 27.PMID: 18955499 2009
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6 | ORC2, ORC3, ORC5, ORC6
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| Origin recognition complex (ORC) mediates histone 3 lysine 4 methylation through cooperation with Spp1 in Saccharomyces cerevisiae.
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| Kan J, Zou L, Zhang J, Wu R, Wang Z, Liang C.
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| J Biol Chem 283(49):33803-7. Epub 2008 Oct 9.PMID: 18845545 2008
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7 | CDT1, ORC1, ORC2, ORC3, ORC4, ORC5, ORC6
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| Interaction between ORC and Cdt1p of Saccharomyces cerevisiae.
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| Asano T, Makise M, Takehara M, Mizushima T.
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| FEMS Yeast Res 7(8):1256-62. Epub 2007 Sep 6.PMID: 17825064 2007
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8 | ORC3
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| Mutation analysis of the origin recognition complex subunit 5 (ORC5L) gene in adult patients with myeloid leukemias exhibiting deletions of chromosome band 7q22.
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| Frohling S, Nakabayashi K, Scherer SW, Dohner H, Dohner K.
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| Hum Genet 108(4):304-9. 2001
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9 | ORC3
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| latheo encodes a subunit of the origin recognition complex and disrupts neuronal proliferation and adult olfactory memory when mutant.
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| Pinto S, Quintana DG, Smith P, Mihalek RM, Hou ZH, Boynton S, Jones CJ, Hendricks M, Velinzon K, Wohlschlegel JA, Austin RJ, Lane WS, Tully T, Dutta A.
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| Neuron 23(1):45-54. 1999
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10 | ORC3
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| Identification and chromosomal localization of murine ORC3, a new member of the mouse origin recognition complex.
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| Springer J, Nanda I, Hoehn K, Schmid M, Grummt F.
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| Cytogenet Cell Genet 87(3-4):245-51. 1999
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11 | ORC3, ORC4, ORC5
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| The Orc4p and Orc5p subunits of the Xenopus and human origin recognition complex are related to Orc1p and Cdc6p.
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| Tugal T, Zou-Yang XH, Gavin K, Pappin D, Canas B, Kobayashi R, Hunt T, Stillman B.
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| J Biol Chem 273(49):32421-9. 1998
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