Citations for
Deficiency in origin licensing proteins impairs cilia formation: implications for the aetiology of Meier-Gorlin syndrome.
Stiff T, Alagoz M, Alcantara D, Outwin E, Brunner HG, Bongers EM, O'Driscoll M, Jeggo PA.
PLoS Genet 9(3):e1003360. doi: 10.1371/journal.pgen.1003360. Epub 2013 Mar 14. 2013
Meier-Gorlin syndrome mutations disrupt an Orc1 CDK inhibitory domain and cause centrosome reduplication.
Hossain M, Stillman B.
Genes Dev 26(16):1797-810. doi: 10.1101/gad.197178.112. Epub 2012 Aug 1. 2012
The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome.
Kuo AJ, Song J, Cheung P, Ishibe-Murakami S, Yamazoe S, Chen JK, Patel DJ, Gozani O.
Nature 484(7392):115-9. doi: 10.1038/nature10956. 2012
Mutations in ORC1, encoding the largest subunit of the origin recognition complex, cause microcephalic primordial dwarfism resembling Meier-Gorlin syndrome.
Bicknell LS, Walker S, Klingseisen A, Stiff T, Leitch A, Kerzendorfer C, Martin CA, Yeyati P, Al Sanna N, Bober M, Johnson D, Wise C, Jackson AP, O'Driscoll M, Jeggo PA.
Nat Genet 43(4):350-5. 2011
Localization of ORC1 during the cell cycle in human leukemia cells.
Coffman FD, Reyes ML, Brown M, Lambert WC, Cohen S.
Anal Cell Pathol (Amst) 34(6):355-61. doi: 10.3233/ACP-2011-0041. 2011
Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization.
Prasanth SG, Shen Z, Prasanth KV, Stillman B.
Proc Natl Acad Sci U S A 107(34):15093-8. Epub 2010 Aug 5.PMID: 20689044 2010
A WD-repeat protein stabilizes ORC binding to chromatin.
Shen Z, Sathyan KM, Geng Y, Zheng R, Chakraborty A, Freeman B, Wang F, Prasanth KV, Prasanth SG.
Mol Cell 40(1):99-111. doi: 10.1016/j.molcel.2010.09.021. 2010
Orc1 controls centriole and centrosome copy number in human cells.
Hemerly AS, Prasanth SG, Siddiqui K, Stillman B.
Science 323(5915):789-93. 2009
Binding of Drosophila ORC proteins to anaphase chromosomes requires cessation of mitotic cyclin-dependent kinase activity.
Baldinger T, Gossen M.
Mol Cell Biol 29(1):140-9. Epub 2008 Oct 27.PMID: 18955499 2009
Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres.
Tatsumi Y, Ezura K, Yoshida K, Yugawa T, Narisawa-Saito M, Kiyono T, Ohta S, Obuse C, Fujita M.
Genes Cells 13(10):1045-59. Epub 2008 Aug 29. 2008
11CDT1, ORC1, ORC2, ORC3, ORC4, ORC5, ORC6
Interaction between ORC and Cdt1p of Saccharomyces cerevisiae.
Asano T, Makise M, Takehara M, Mizushima T.
FEMS Yeast Res 7(8):1256-62. Epub 2007 Sep 6.PMID: 17825064 2007
The ORC1 cycle in human cells: II. Dynamic changes in the human ORC complex during the cell cycle.
Ohta S, Tatsumi Y, Fujita M, Tsurimoto T, Obuse C.
J Biol Chem 278(42):41535-40. Epub 2003 Aug 8. 2003
Mapping of the human homologue (ORC1L) of the yeast origin recognition complex subunit 1 gene to chromosome band 1p32.
Eki T, et al.
Genomics 36 : 559-561. 1996