Citations for
1MGORS1, ORC1
Deficiency in origin licensing proteins impairs cilia formation: implications for the aetiology of Meier-Gorlin syndrome.
Stiff T, Alagoz M, Alcantara D, Outwin E, Brunner HG, Bongers EM, O'Driscoll M, Jeggo PA.
PLoS Genet 9(3):e1003360. doi: 10.1371/journal.pgen.1003360. Epub 2013 Mar 14. 2013
2MGORS1, ORC1
Meier-Gorlin syndrome mutations disrupt an Orc1 CDK inhibitory domain and cause centrosome reduplication.
Hossain M, Stillman B.
Genes Dev 26(16):1797-810. doi: 10.1101/gad.197178.112. Epub 2012 Aug 1. 2012
3MGORS1, ORC1
The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome.
Kuo AJ, Song J, Cheung P, Ishibe-Murakami S, Yamazoe S, Chen JK, Patel DJ, Gozani O.
Nature 484(7392):115-9. doi: 10.1038/nature10956. 2012
4MGORS1, ORC1
Mutations in ORC1, encoding the largest subunit of the origin recognition complex, cause microcephalic primordial dwarfism resembling Meier-Gorlin syndrome.
Bicknell LS, Walker S, Klingseisen A, Stiff T, Leitch A, Kerzendorfer C, Martin CA, Yeyati P, Al Sanna N, Bober M, Johnson D, Wise C, Jackson AP, O'Driscoll M, Jeggo PA.
Nat Genet 43(4):350-5. 2011
5ORC1
Localization of ORC1 during the cell cycle in human leukemia cells.
Coffman FD, Reyes ML, Brown M, Lambert WC, Cohen S.
Anal Cell Pathol (Amst) 34(6):355-61. doi: 10.3233/ACP-2011-0041. 2011
6CBX5, ORC1, ORC2, ORC3
Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization.
Prasanth SG, Shen Z, Prasanth KV, Stillman B.
Proc Natl Acad Sci U S A 107(34):15093-8. Epub 2010 Aug 5.PMID: 20689044 2010
7LRWD1, ORC1, ORC2
A WD-repeat protein stabilizes ORC binding to chromatin.
Shen Z, Sathyan KM, Geng Y, Zheng R, Chakraborty A, Freeman B, Wang F, Prasanth KV, Prasanth SG.
Mol Cell 40(1):99-111. doi: 10.1016/j.molcel.2010.09.021. 2010
8ORC1
Orc1 controls centriole and centrosome copy number in human cells.
Hemerly AS, Prasanth SG, Siddiqui K, Stillman B.
Science 323(5915):789-93. 2009
9ORC1, ORC2, ORC3
Binding of Drosophila ORC proteins to anaphase chromosomes requires cessation of mitotic cyclin-dependent kinase activity.
Baldinger T, Gossen M.
Mol Cell Biol 29(1):140-9. Epub 2008 Oct 27.PMID: 18955499 2009
10ORC1
Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres.
Tatsumi Y, Ezura K, Yoshida K, Yugawa T, Narisawa-Saito M, Kiyono T, Ohta S, Obuse C, Fujita M.
Genes Cells 13(10):1045-59. Epub 2008 Aug 29. 2008
11CDT1, ORC1, ORC2, ORC3, ORC4, ORC5, ORC6
Interaction between ORC and Cdt1p of Saccharomyces cerevisiae.
Asano T, Makise M, Takehara M, Mizushima T.
FEMS Yeast Res 7(8):1256-62. Epub 2007 Sep 6.PMID: 17825064 2007
12ORC1
The ORC1 cycle in human cells: II. Dynamic changes in the human ORC complex during the cell cycle.
Ohta S, Tatsumi Y, Fujita M, Tsurimoto T, Obuse C.
J Biol Chem 278(42):41535-40. Epub 2003 Aug 8. 2003
13ORC1
Mapping of the human homologue (ORC1L) of the yeast origin recognition complex subunit 1 gene to chromosome band 1p32.
Eki T, et al.
Genomics 36 : 559-561. 1996