| 1 | OPRL1, OPRM1
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| Elevated methylation of OPRM1 and OPRL1 genes in Alzheimer's disease.
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| Xu C, Liu G, Ji H, Chen W, Dai D, Chen Z, Zhou D, Xu L, Hu H, Cui W, Chang L, Zha Q, Li L, Duan S, Wang Q.
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| Mol Med Rep 18(5):4297-4302. doi: 10.3892/mmr.2018.9424. Epub 2018 Aug 24.
2018
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| 2 | OPRK1, OPRM1
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| Differential stability of the crystallographic interfaces of mu- and kappa-opioid receptors.
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| Johnston JM, Filizola M.
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| PLoS One 9(2):e90694. doi: 10.1371/journal.pone.0090694. eCollection 2014.
2014
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| 3 | OPRM1
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| MOR is not enough: identification of novel mu-opioid receptor interacting proteins using traditional and modified membrane yeast two-hybrid screens.
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| Petko J, Justice-Bitner S, Jin J, Wong V, Kittanakom S, Ferraro TN, Stagljar I, Levenson R.
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| PLoS One 8(6):e67608. doi: 10.1371/journal.pone.0067608. Print 2013.
2013
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| 4 | OPRM1, TRPM8
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| Opiates modulate thermosensation by internalizing cold receptor TRPM8.
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| Shapovalov G, Gkika D, Devilliers M, Kondratskyi A, Gordienko D, Busserolles J, Bokhobza A, Eschalier A, Skryma R, Prevarskaya N.
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| Cell Rep 4(3):504-15. doi: 10.1016/j.celrep.2013.07.002. Epub 2013 Aug 1.
2013
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| 5 | OPRM1, PCBP1, RACK1
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| RACK1 identified as the PCBP1-interacting protein with a novel functional role on the regulation of human MOR gene expression.
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| Nahar-Gohad P, Sultan H, Esteban Y, Stabile A, Ko JL.
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| J Neurochem Neurochem. 2012 Nov 22. doi: 10.1111/jnc.12100. [Epub ahead of print] 2012
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| 6 | EGFR, OPRM1
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| OPRM1 and EGFR contribute to skin pigmentation differences between Indigenous Americans and Europeans.
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| Quillen EE, Bauchet M, Bigham AW, Delgado-Burbano ME, Faust FX, Klimentidis YC, Mao X, Stoneking M, Shriver MD.
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| Hum Genet 131(7):1073-80. doi: 10.1007/s00439-011-1135-1. Epub 2011 Dec 24.
2012
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| 7 | OPRM1
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| Hypermethylation of OPRM1 promoter region in European Americans with alcohol dependence.
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| Zhang H, Herman AI, Kranzler HR, Anton RF, Simen AA, Gelernter J.
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| J Hum Genet 57(10):670-5. doi: 10.1038/jhg.2012.98. Epub 2012 Aug 23.
2012
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| 8 | OPRM1
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| Differential gene expression activity among species-specific polypyrimidine/polypurine motifs in mu opioid receptor gene promoters.
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| Choe CY, Dong J, Law PY, Loh HH.
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| Gene 471(1-2):27-36. Epub 2010 Oct 12.
2011
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| 9 | OPRD1, OPRM1
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| Facilitation of μ-opioid receptor activity by preventing δ-opioid receptor-mediated codegradation.
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| He SQ, Zhang ZN, Guan JS, Liu HR, Zhao B, Wang HB, Li Q, Yang H, Luo J, Li ZY, Wang Q, Lu YJ, Bao L, Zhang X.
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| Neuron 69(1):120-31.
2011
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| 10 | OPRD1, OPRM1, RGS4
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| Opioid-induced down-regulation of RGS4: role of ubiquitination and implications for receptor cross-talk.
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| Wang Q, Traynor JR.
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| J Biol Chem 286(10):7854-64. Epub 2011 Jan 5.
2011
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| 11 | OPRM1
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| Human Mu Opioid Receptor (OPRM1 A118G) polymorphism is associated with brain mu-opioid receptor binding potential in smokers.
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| Ray R, Ruparel K, Newberg A, Wileyto EP, Loughead JW, Divgi C, Blendy JA, Logan J, Zubieta JK, Lerman C.
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| Proc Natl Acad Sci U S A 108(22):9268-73. Epub 2011 May 16.
2011
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| 12 | OPRM1
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| Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects.
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| Majumdar S, Grinnell S, Le Rouzic V, Burgman M, Polikar L, Ansonoff M, Pintar J, Pan YX, Pasternak GW.
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| Proc Natl Acad Sci U S A 108(49):19778-83. doi: 10.1073/pnas.1115231108. Epub 2011 Nov 21.
2011
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| 13 | OPRM1
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| Functional characterization of human variants of the mu-opioid receptor gene.
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| Ravindranathan A, Joslyn G, Robertson M, Schuckit MA, Whistler JL, White RL.
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| Proc Natl Acad Sci U S A 106(26):10811-6. Epub 2009 Jun 15.
2009
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| 14 | OPRD1, OPRM1, RGS4
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| Regulator of G protein signaling 4 confers selectivity to specific G proteins to modulate mu- and delta-opioid receptor signaling.
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| Leontiadis LJ, Papakonstantinou MP, Georgoussi Z.
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| Cell Signal 21(7):1218-28. Epub 2009 Mar 24.PMID: 19324084 2009
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| 15 | OPRD1, OPRM1
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| Differential effect of membrane cholesterol removal on mu- and delta-opioid receptors: a parallel comparison of acute and chronic signaling to adenylyl cyclase.
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| Levitt ES, Clark MJ, Jenkins PM, Martens JR, Traynor JR.
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| J Biol Chem 284(33):22108-22. Epub 2009 Jun 11.
2009
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| 16 | OPRD1, OPRM1
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| Expression of delta- and mu-opioid receptors in the ventricular and subventricular zones of the developing human neocortex.
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| Tripathi A, Khurshid N, Kumar P, Iyengar S.
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| Neurosci Res 61(3):257-70. Epub 2008 Mar 25.
2008
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| 17 | OPRM1, PPP1R9B
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| Multiple actions of spinophilin regulate mu opioid receptor function.
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| Charlton JJ, Allen PB, Psifogeorgou K, Chakravarty S, Gomes I, Neve RL, Devi LA, Greengard P, Nestler EJ, Zachariou V.
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| Neuron 58(2):238-47.
2008
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| 18 | OPRM1
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| Interaction of the mu-opioid receptor with synaptophysin influences receptor trafficking and signaling.
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| Liang YJ, Wu DF, Yang LQ, Hollt V, Koch T.
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| Mol Pharmacol 71(1):123-31. Epub 2006 Sep 27. 2007
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| 19 | GNAZ, HINT1, OPRM1, RGS20
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| RGSZ1 interacts with protein kinase C interacting protein PKCI-1 and modulates mu opioid receptor signaling.
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| Ajit SK, Ramineni S, Edris W, Hunt RA, Hum WT, Hepler JR, Young KH.
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| Cell Signal 19(4):723-30. Epub 2006 Oct 7.
2007
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| 20 | OPRM1
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| Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters.
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| Hwang CK, Song KY, Kim CS, Choi HS, Guo XH, Law PY, Wei LN, Loh HH.
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| Mol Cell Biol 27(13):4720-36. Epub 2007 Apr 23.
2007
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| 21 | OPRD1, OPRM1
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| The opioid system in alcohol and drug dependence: family-based association study.
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| Xuei X, Flury-Wetherill L, Bierut L, Dick D, Nurnberger J Jr, Foroud T, Edenberg HJ.
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| Am J Med Genet B Neuropsychiatr Genet 144B(7):877-84.
2007
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| 22 | OPRM1
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| Association of the mu-opioid receptor gene with type 2 diabetes mellitus in an African American population.
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| Gallagher CJ, Gordon CJ, Langefeld CD, Mychaleckyj JC, Freedman BI, Rich SS, Bowden DW, Sale MM.
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| Mol Genet Metab 87(1):54-60. Epub 2005 Sep 2. 2006
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| 23 | OPRM1
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| Association between two {micro}-opioid receptor gene (OPRM1) haplotype blocks and drug or alcohol dependence.
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| Zhang H, Luo X, Kranzler HR, Lappalainen J, Yang BZ, Krupitsky E, Zvartau E, Gelernter J.
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| Hum Mol Genet 15(6):807-19. Epub 2006 Feb 13. 2006
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| 24 | OPRM1
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| Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm.
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| Pan L, Xu J, Yu R, Xu MM, Pan YX, Pasternak GW.
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| Neuroscience 133(1):209-20. 2005
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| 25 | REST, OPRM1
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| Neuron-restrictive silencer factor (NRSF) functions as a repressor in neuronal cells to regulate the mu opioid receptor gene.
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| Kim CS, Hwang CK, Choi HS, Song KY, Law PY, Wei LN, Loh HH.
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| J Biol Chem 279(45):46464-73. Epub 2004 Aug 18. 2004
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| 26 | OPRM1
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| Molecular identification and functional expression of mu 3, a novel alternatively spliced variant of the human mu opiate receptor gene.
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| Cadet P, Mantione KJ, Stefano GB.
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| J Immunol 170(10):5118-23. 2003
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| 27 | OPRM1, REST
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| Identification of a neurorestrictive suppressor element (NRSE) in the human mu-opioid receptor gene.
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| Andria ML, Simon EJ.
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| Brain Res Mol Brain Res 91(1-2):73-80. 2001
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| 28 | OPRM1
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| Transcriptional regulation of the human mu opioid receptor (hMOR) gene: evidence of positive and negative cis-acting elements in the proximal promoter and presence of a distal promoter.
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| Xu Y, Carr LG.
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| DNA Cell Biol 20(7):391-402. 2001
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| 29 | OPRM1
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| Isolation and expression of a novel alternatively spliced mu opioid receptor isoform, MOR-1F.
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| Pan YX, Xu J, Bolan E, Chang A, Mahurter L, Rossi G, Pasternak GW.
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| FEBS Lett 466(2-3):337-40. 2000
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| 30 | OPRM1
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| Specific activation of the mu opioid receptor (MOR) by endomorphin 1 and endomorphin 2.
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| Monory K, Bourin MC, Spetea M, Tomboly C, Toth G, Matthes HW, Kieffer BL, Hanoune J, Borsodi A.
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| Eur J Neurosci 12(2):577-84. 2000
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| 31 | OPRM1
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| Sequence variability and candidate gene analysis in complex disease: association of mu opioid receptor gene variation with substance dependence.
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| Hoehe MR, Kopke K, Wendel B, Rohde K, Flachmeier C, Kidd KK, Berrettini WH, Church GM.
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| Hum Mol Genet 9(19):2895-908. 2000
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| 32 | OPRD1, OPRM1
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| Gene expressions of opioid receptors and G-proteins in pineal glands.
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| Chetsawang B, Casalotti SO, Phansuwan-Pujito P, Kotchabhakdi N, Govitrapong P.
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| Biochem Biophys Res Commun 262(3):775-80 1999
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| 33 | OPRM1
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| Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity : possible implications for opiate addiction.
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| Bond C, et al.
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| Proc Natl Acad Sci U S A 95 : 9608-9613. 1998
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| 34 | OPRM1
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| Antisense mapping the MOR-1 opioid receptor : evidence for alternative splicing and a novel morphine-6beta-glucuronide receptor.
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| Rossi GC, et al.
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| FEBS Lett 369 : 192-196. 1995
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| 35 | OPRM1
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| Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment.
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| Wang JB, et al.
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| FEBS Lett 338 : 217-222. 1994
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| 36 | OPRM1
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| Expression of two variants of the human mu opioid receptor mRNA in SK-N-SH cells and human brain.
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| Bare L, et al.
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| FEBS Lett 354 : 213-216. 1994
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| 37 | OPRM1
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| Ide S, Han W, Kasai S, Hata H, Sora I, Ikeda K.
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|
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| Characterization of the 3' untranslated region of the human mu-opioid receptor (MOR-1) mRNA haracterization of the 3' untranslated region of the human mu-opioid receptor (MOR-1) mRNA. 0
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