1 | DELE1, OMA1
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| A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol.
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| Fessler E, Eckl EM, Schmitt S, Mancilla IA, Meyer-Bender MF, Hanf M, Philippou-Massier J, Krebs S, Zischka H, Jae LT
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| Nature. Mar;579(7799):433-437. doi: 10.1038/s41586-020-2076-4. Epub 2020 Mar 4. 2020
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2 | OMA1
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| Metalloproteases of the inner mitochondrial membrane.
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| Levytskyy R, Bohovych I, Khalimonchuk O.
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| Biochemistry iochemistry. 2017 Aug 14. doi: 10.1021/acs.biochem.7b00663. [Epub ahead of print]
2017
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3 | DRP1, OMA1
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| A threshold of transmembrane potential is required for mitochondrial dynamic balance mediated by DRP1 and OMA1.
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| Jones E, Gaytan N, Garcia I, Herrera A, Ramos M, Agarwala D, Rana M, Innis-Whitehouse W, Schuenzel E, Gilkerson R.
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| Cell Mol Life Sci 74(7):1347-1363. doi: 10.1007/s00018-016-2421-9. Epub 2016 Nov 17.
2017
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4 | OMA1, OPA1, YME1L1
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| Reciprocal Degradation of YME1L and OMA1 Adapts Mitochondrial Proteolytic Activity during Stress.
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| Rainbolt TK, Lebeau J, Puchades C, Wiseman RL.
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| Cell Rep 14(9):2041-9. doi: 10.1016/j.celrep.2016.02.011. Epub 2016 Feb 25.
2016
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5 | OMA1, OPA1
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| Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria.
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| Korwitz A, Merkwirth C, Richter-Dennerlein R, Tröder SE, Sprenger HG, Quirós PM, López-Otín C, Rugarli EI, Langer T.
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| J Cell Biol 212(2):157-66. doi: 10.1083/jcb.201507022.
2016
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6 | OMA1
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| Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability.
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| Bohovych I, Fernandez MR, Rahn JJ, Stackley KD, Bestman JE, Anandhan A, Franco R, Claypool SM, Lewis RE, Chan SS, Khalimonchuk O.
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| Sci Rep 5:13989. doi: 10.1038/srep13989.
2015
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7 | BAK1, BAX, OMA1
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| Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis.
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| Jiang X, Jiang H, Shen Z, Wang X.
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| Proc Natl Acad Sci U S A 111(41):14782-7. doi: 10.1073/pnas.1417253111. Epub 2014 Oct 1.
2014
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8 | OMA1, OPA1
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| Membrane depolarization activates the mitochondrial protease OMA1 by stimulating self-cleavage.
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| Zhang K, Li H, Song Z.
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| EMBO Rep 15(5):576-85. doi: 10.1002/embr.201338240. Epub 2014 Apr 9.
2014
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9 | OMA1, OPA1, YME1L1
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| The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission.
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| Anand R, Wai T, Baker MJ, Kladt N, Schauss AC, Rugarli E, Langer T.
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| J Cell Biol 204(6):919-29. doi: 10.1083/jcb.201308006. Epub 2014 Mar 10.
2014
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10 | OMA1, OPA1
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| Stress-induced OMA1 activation and autocatalytic turnover regulate OPA1-dependent mitochondrial dynamics.
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| Baker MJ, Lampe PA, Stojanovski D, Korwitz A, Anand R, Tatsuta T, Langer T.
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| EMBO J 33(6):578-93. doi: 10.1002/embj.201386474. Epub 2014 Feb 18.
2014
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11 | OMA1, OPA1
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| Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1.
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| Ehses S, Raschke I, Mancuso G, Bernacchia A, Geimer S, Tondera D, Martinou JC, Westermann B, Rugarli EI, Langer T.
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| J Cell Biol 187(7):1023-36. doi: 10.1083/jcb.200906084.
2009
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12 | OMA1, OPA1, YME1L1
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| Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells.
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| Head B, Griparic L, Amiri M, Gandre-Babbe S, van der Bliek AM.
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| J Cell Biol 187(7):959-66. doi: 10.1083/jcb.200906083.
2009
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13 | FYN, LRP8, OMA1
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| Fyn modulation of Dab1 effects on amyloid precursor protein and ApoE receptor 2 processing.
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| Hoe HS, Minami SS, Makarova A, Lee J, Hyman BT, Matsuoka Y, Rebeck GW.
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| J Biol Chem 283(10):6288-99. Epub 2007 Dec 18.PMID: 18089558 2008
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14 | CUL5, OMA1
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| Cullin 5 regulates Dab1 protein levels and neuron positioning during cortical development.
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| Feng L, Allen NS, Simo S, Cooper JA.
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| Genes Dev 21(21):2717-30. 2007
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