1 | CCL2, F3, OLR1, TICAM1, TLR2
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| TRIF is a regulator of TLR2-induced foam cell formation.
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| Huang B, Park DW, Baek SH.
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| Mol Med Rep 14(4):3329-35. doi: 10.3892/mmr.2016.5647. Epub 2016 Aug 19.
2016
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2 | CAPN1, CAPN2, OLR1
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| LOX-1 in macrophage migration in response to ox-LDL and the involvement of calpains.
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| Wang X, Ding Z, Lin J, Guo Z, Mehta JL.
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| Biochem Biophys Res Commun 467(1):135-9. doi: 10.1016/j.bbrc.2015.09.100. Epub 2015 Sep 21.
2015
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3 | OLR1, PCSK9
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| Cross-talk between LOX-1 and PCSK9 in vascular tissues.
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| Ding Z, Liu S, Wang X, Deng X, Fan Y, Shahanawaz J, Shmookler Reis RJ, Varughese KI, Sawamura T, Mehta JL.
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| Cardiovasc Res 107(4):556-67. doi: 10.1093/cvr/cvv178. Epub 2015 Jun 19.
2015
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4 | OLR1
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| LOX-1 deletion and macrophage trafficking in atherosclerosis.
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| Ding Z, Mizeracki AM, Hu C, Mehta JL.
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| Biochem Biophys Res Commun 440(2):210-4. doi: 10.1016/j.bbrc.2013.09.020. Epub 2013 Sep 12.
2013
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5 | CCL2, OLR1
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| Ox-LDL promotes migration and adhesion of bone marrow-derived mesenchymal stem cells via regulation of MCP-1 expression.
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| Zhang F, Wang C, Wang H, Lu M, Li Y, Feng H, Lin J, Yuan Z, Wang X.
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| Mediators Inflamm 2013:691023. doi: 10.1155/2013/691023. Epub 2013 Jul 17.
2013
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6 | OLR1
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| Simulative and experimental investigation on the cleavage site that generates the soluble human LOX-1.
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| Biocca S, Arcangeli T, Tagliaferri E, Testa B, Vindigni G, Oteri F, Giorgi A, Iacovelli F, Novelli G, Desideri A, Falconi M.
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| Arch Biochem Biophys 540(1-2):9-18. doi: 10.1016/j.abb.2013.10.001. Epub 2013 Oct 7.
2013
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7 | OLR1
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| LOX-1 in the maintenance of cytoskeleton and proliferation in senescent cardiac fibroblasts.
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| Wang X, Khaidakov M, Ding Z, Dai Y, Mercanti F, Mehta JL.
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| J Mol Cell Cardiol 60:184-90. doi: 10.1016/j.yjmcc.2013.04.024. Epub 2013 May 3.
2013
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8 | OLR1
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| Lectin-like oxidized LDL receptor-1 is palmitoylated and internalizes ligands via caveolae/raft-dependent endocytosis.
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| Kumano-Kuramochi M, Xie Q, Kajiwara S, Komba S, Minowa T, Machida S.
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| Biochem Biophys Res Commun 434(3):594-9. doi: 10.1016/j.bbrc.2013.03.120. Epub 2013 Apr 10.
2013
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9 | OLR1
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| Detection of acute aortic dissection by extremely high soluble lectin-like oxidized LDL receptor-1 (sLOX-1) and low troponin T levels in blood.
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| Kobayashi N, Hata N, Kume N, Yokoyama S, Takano M, Shinada T, Tomita K, Shirakabe A, Inami T, Seino Y, Mizuno K.
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| Int J Cardiol 165(3):557-9. doi: 10.1016/j.ijcard.2012.09.001. Epub 2012 Sep 26. No abstract available.
2013
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10 | CCL2, LPA, OLR1
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| MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma.
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| Wiesner P, Tafelmeier M, Chittka D, Choi SH, Zhang L, Byun YS, Almazan F, Yang X, Iqbal N, Chowdhury P, Maisel A, Witztum JL, Handel TM, Tsimikas S, Miller YI.
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| J Lipid Res 54(7):1877-83. doi: 10.1194/jlr.M036343. Epub 2013 May 10.
2013
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11 | CD36, MSR1, OLR1
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| Regulation of MSR-1 and CD36 in macrophages by LOX-1 mediated through PPAR-γ.
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| Dai Y, Su W, Ding Z, Wang X, Mercanti F, Chen M, Raina S, Mehta JL.
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| Biochem Biophys Res Commun 431(3):496-500. doi: 10.1016/j.bbrc.2013.01.029. Epub 2013 Jan 16.
2013
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12 | OLR1
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| Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) and cardiac fibroblast growth.
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| Wang X, Khaidakov M, Ding Z, Mitra S, Lu J, Dai Y, Mehta JL.
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| Hypertension 60(6):1437-42. doi: 10.1161/HYPERTENSIONAHA.112.200659. Epub 2012 Oct 8.
2012
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13 | OLR1
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| Increased lectin-like oxidized LDL receptor-1 expression in the placentas of women with intrahepatic cholestasis during pregnancy.
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| Yin Y, Zhu QY, Ren SJ, Wang DM.
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| Clin Exp Obstet Gynecol 39(2):149-52.
2012
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14 | OLR1
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| The new role of LOX-1 in hypertension induced neuronal apoptosis.
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| Li Y, Duan Z, Gao D, Huang S, Yuan H, Niu X.
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| Biochem Biophys Res Commun 425(4):735-40. doi: 10.1016/j.bbrc.2012.07.143. Epub 2012 Aug 2.
2012
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15 | NFE2L2, OLR1
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| Decreased lectin-like oxidized LDL receptor 1 (LOX-1) and low Nrf2 activation in placenta are involved in preeclampsia.
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| Chigusa Y, Tatsumi K, Kondoh E, Fujita K, Nishimura F, Mogami H, Konishi I.
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| J Clin Endocrinol Metab 97(10):E1862-70. doi: 10.1210/jc.2012-1268. Epub 2012 Jul 12.
2012
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16 | OLR1
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| Upregulation of lectin-like oxidized low density lipoprotein receptor 1 (LOX-1) expression in human endothelial cells by modified high density lipoproteins.
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| Pirillo A, Uboldi P, Ferri N, Corsini A, Kuhn H, Catapano AL.
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| Biochem Biophys Res Commun 428(2):230-3. doi: 10.1016/j.bbrc.2012.10.020. Epub 2012 Oct 13.
2012
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17 | HSPD1, OLR1
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| Microglial LOX-1 reacts with extracellular HSP60 to bridge neuroinflammation and neurotoxicity.
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| Zhang D, Sun L, Zhu H, Wang L, Wu W, Xie J, Gu J.
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| Neurochem Int 61(7):1021-35. doi: 10.1016/j.neuint.2012.07.019. Epub 2012 Jul 27.
2012
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18 | OLR1
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| Lectin-like oxidized LDL receptor 1 is involved in CRP-mediated complement activation.
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| Fujita Y, Yamaguchi S, Kakino A, Iwamoto S, Yoshimoto R, Sawamura T.
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| Clin Chem 57(10):1398-405. doi: 10.1373/clinchem.2011.168625. Epub 2011 Aug 5.
2011
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19 | OLR1
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| Potential involvement of LOX-1 in functional consequences of endothelial senescence.
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| Khaidakov M, Wang X, Mehta JL.
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| PLoS One 6(6):e20964. doi: 10.1371/journal.pone.0020964. Epub 2011 Jun 15.
2011
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20 | OLR1, ROCK2
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| ROCK2 associates with lectin-like oxidized LDL receptor-1 and mediates oxidized LDL-induced IL-8 production.
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| Mattaliano MD, Wooters J, Shih HH, Paulsen JE.
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| Am J Physiol Cell Physiol 298(5):C1180-7. doi: 10.1152/ajpcell.00483.2009. Epub 2010 Feb 24.
2010
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21 | OLR1
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| LOX-1 dependent overexpression of immunoglobulins in cardiomyocytes in response to angiotensin II.
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| Kang BY, Hu C, Prayaga S, Khaidakov M, Sawamura T, Seung KB, Mehta JL.
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| Biochem Biophys Res Commun 379(2):395-9. Epub 2009 Jan 4.
2009
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22 | OLR1
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| Lectin-like oxidized LDL receptor-1 (LOX-1) expression in the tubulointerstitial area likely plays an important role in human diabetic nephropathy.
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| Yamamoto N, Toyoda M, Abe M, Kobayashi T, Kobayashi K, Kato M, Miyauchi M, Kimura M, Umezono T, Suzuki D.
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| Intern Med 48(4):189-94. Epub 2009 Feb 16.
2009
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23 | CETP, LPL, MTHFR, NOS3, OLR1, PAPPA, SERPINE1
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| Candidate gene polymorphisms and the 9p21 locus in acute coronary syndromes.
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| Tousoulis D, Briasoulis A, Papageorgiou N, Antoniades C, Stefanadis C.
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| Trends Mol Med rends Mol Med. 2008 Sep 9. [Epub ahead of print]
2008
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24 | OLR1
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| The splice variant LOXIN inhibits LOX-1 receptor function through hetero-oligomerization.
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| Biocca S, Filesi I, Mango R, Maggiore L, Baldini F, Vecchione L, Viola A, Citro G, Federici G, Romeo F, Novelli G.
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| J Mol Cell Cardiol 44(3):561-70. Epub 2007 Dec 7.PMID: 18191942 2008
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25 | OLR1
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| Lectin-like oxidized low-density lipoprotein receptor (LOX-1) functions as an oligomer and oligomerization is dependent on receptor density.
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| Matsunaga S, Xie Q, Kumano M, Niimi S, Sekizawa K, Sakakibara Y, Komba S, Machida S.
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| Exp Cell Res 313(6):1203-14. Epub 2007 Jan 17. Erratum in: Exp Cell Res. 2007 Jul 15;313(12):2752.
2007
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26 | OLR1
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| OLR1 gene and coronary artery disease/acute myocardial infarction: replication in an independently collected sample.
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| Novelli G, Borgiani P, Mango R, Romeo F, Mehta JL.
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| Eur J Hum Genet 14(8):894-5; author reply 895. Epub 2006 May 17. No abstract available. 2006
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27 | OLR1
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| LOX-1 scavenger receptor mediates calcium-dependent recognition of phosphatidylserine and apoptotic cells.
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| Murphy JE, Tacon D, Tedbury PR, Hadden JM, Knowling S, Sawamura T, Peckham M, Phillips SE, Walker JH, Ponnambalam S.
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| Biochem J 393(Pt 1):107-15. 2006
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28 | OLR1
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| Association of single nucleotide polymorphisms in the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction.
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| Mango R, Clementi F, Borgiani P, Forleo GB, Federici M, Contino G, Giardina E, Garza L, Fahdi IE, Lauro R, Mehta JL, Novelli G, Romeo F.
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| J Med Genet 40(12):933-6. No abstract available. 2003
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29 | OLR1
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| Genetic variation in lectin-like oxidized low-density lipoprotein receptor 1 (LOX1) gene and the risk of coronary artery disease.
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| Chen Q, Reis SE, Kammerer C, Craig WY, LaPierre SE, Zimmer EL, McNamara DM, Pauly DF, Sharaf B, Holubkov R, Bairey Merz CN, Sopko G, Bontempo F, Kamboh MI.
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| Circulation 107(25):3146-51. Epub 2003 Jun 16. 2003
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30 | AD5, OLR1
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| Investigation of oxidized LDL-receptor 1 (OLR1) as the candidate gene for Alzheimer's disease on chromosome 12.
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| Luedecking-Zimmer E, DeKosky ST, Chen Q, Barmada MM, Kamboh MI.
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| Hum Genet 111(4-5):443-51. 2002
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31 | OLR1
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| Identification, regulation and function of a novel lectin-like oxidized low-density lipoprotein receptor.
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| Mehta JL, Li D.
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| J Am Coll Cardiol 39(9):1429-35. Review. 2002
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32 | OLR1
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| Diabetes enhances lectin-like oxidized LDL receptor-1 (LOX-1) expression in the vascular endothelium: possible role of LOX-1 ligand and AGE.
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| Chen M, Nagase M, Fujita T, Narumiya S, Masaki T, Sawamura T.
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| Biochem Biophys Res Commun 287(4):962-8. 2001
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33 | OLR1
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| Structure and chromosomal assignment of the human lectin-like oxidized low-density-lipoprotein receptor-1 (LOX-1) gene.
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| Aoyama T, et al.
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| Biochem J 339 ( Pt 1):177-84. 1999
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34 | OLR1
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| Assignment of the human oxidized low-density lipoprotein receptor gene (OLR1) to chromosome 12p13.1-p12.3, and identification of a polymorphic CA-repeat marker in the OLR1 gene.
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| Li X, et al.
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| Cytogenet Cell Genet 82 : 34-36. 1998
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35 | OLR1
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| The human gene encoding the lectin-type oxidized LDL receptor (OLR1) is a novel member of the natural killer gene complex with a unique expression profile.
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| Yamanaka S, et al.
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| Genomics 54 : 191-199. 1998
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36 | OLR1
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| Genomic organization and regulation of expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1) gene.
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| Nagase M, et al.
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| J Biol Chem 273 : 33702-33707. 1998
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37 | OLR1
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| An endothelial receptor for oxidized low-density lipoprotein.
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| Sawamura T, et al.
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| Nature 386 : 73-77. 1997
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