| 1 | OLIG1, OLIG2, OLIG3
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| Biological functions of the Olig gene family in brain cancer and therapeutic targeting.
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| Szu JI, Tsigelny IF, Wojcinski A, Kesari S.
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| Front Neurosci May 18;17:1129434. doi: 10.3389/fnins.2023.1129434 2023
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| 2 | OLIG2
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| Disruption of the anterior commissure in Olig2 deficient mice
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| Gotoh H, Maruyama K, Yoshii K, Yamauchi N, Nomura T, Ohtsuka S, Shirasaki R, Takebayashi H, Ono K.
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| Eur J Neurosci. Jan;57(1):5-16. doi: 10.1111/ejn.15861. Epub 2022 Nov 23. 2023
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| 3 | OLIG2, SETDB1
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| The Oligodendrocyte Transcription Factor 2 OLIG2 regulates transcriptional repression during myelinogenesis in rodents.
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| Zhang K, Chen S, Yang Q, Guo S, Chen Q, Liu Z, Li L, Jiang M, Li H, Hu J, Pan X, Deng W, Xiao N, Wang B, Wang ZX, Zhang L, Mo W.
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| Nat Commun. Mar 17;13(1):1423. doi: 10.1038/s41467-022-29068-z. Erratum in: Nat Commun. 2022 Jun 1;13(1):3164 2022
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| 4 | OLIG1, OLIG2
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| Impact of the Olig Family on Neurodevelopmental Disorders.
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| Szu J, Wojcinski A, Jiang P, Kesari S
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| Front Neurosci. Mar 30;15:659601. doi: 10.3389/fnins.2021.659601. 2021
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| 5 | OLIG2
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| Region-specific distribution of Olig2-expressing astrocytes in adult mouse brain and spinal cord.
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| Wang H, Xu L, Lai C, Hou K, Chen J, Guo Y, Sambangi A, Swaminathan S, Xie C, Wu Z, Chen G.
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| Mol Brain. Feb 17;14(1):36. doi: 10.1186/s13041-021-00747-0. 2021
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| 6 | OLIG1, OLIG2
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| Olig2 regulates terminal differentiation and maturation of peripheral olfactory sensory neurons. Cell Mol
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| Wang YZ, Fan H, Ji Y, Reynolds K, Gu R, Gan Q, Yamagami T, Zhao T, Hamad S, Bizen N, Takebayashi H, Chen Y, Wu S, Pleasure D, Lam K, Zhou CJ.
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| Life Sci. Sep;77(18):3597-3609. doi: 10.1007/s00018-019-03385-x. Epub 2019 Nov 22. Erratum in: Cell Mol Life Sci. 2021 Jul;78(14):5665-56 2020
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| 7 | NEUROG2, OLIG2
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| WNT signaling suppresses oligodendrogenesis via Ngn2-dependent direct inhibition of Olig2 expression.
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| Jiang M, Yu D, Xie B, Huang H, Lu W, Qiu M, Dai ZM.
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| Mol Brain. Nov 13;13(1):155. doi: 10.1186/s13041-020-00696-0. 2020
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| 8 | BRD7, OLIG2, SEH1L
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| Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination
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| Liu Z, Yan M, Liang Y, Liu M, Zhang K, Shao D, Jiang R, Li L, Wang C, Nussenzveig DR, Zhang K, Chen S, Zhong C, Mo W, Fontoura BMA, Zhang L.
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| Neuron May 8;102(3):587-601.e7. doi: 10.1016/j.neuron.2019.02.018. Epub 2019 Mar 12. 2019
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| 9 | OLIG2
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| Olig2-Lineage Astrocytes: A Distinct Subtype of Astrocytes That Differs from GFAP Astrocytes.
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| Tatsumi K, Isonishi A, Yamasaki M, Kawabe Y, Morita-Takemura S, Nakahara K, Terada Y, Shinjo T, Okuda H, Tanaka T, Wanaka A.
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| Front Neuroanat. Feb 14;12:8. doi: 10.3389/fnana.2018.00008. 2018
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| 10 | OLIG2
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| The transcription factor Olig2 is important for the biology of diffuse intrinsic pontine gliomas.
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| Anderson JL, Muraleedharan R, Oatman N, Klotter A, Sengupta S, Waclaw RR, Wu J, Drissi R, Miles L, Raabe EH, Weirauch ML, Fouladi M, Chow LM, Hoffman L, DeWire M, Dasgupta B.
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| Neuro Oncol. Aug1;19(8):1068-1078. doi: 10.1093/neuonc/now299. 2017
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| 11 | OLIG1, OLIG2
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| Olig2 regulates Purkinje cell generation in the early developing mouse cerebellum.
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| Ju J, Liu Q, Zhang Y, Liu Y, Jiang M, Zhang L, He X, Peng C, Zheng T, Lu QR, Li H.
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| Sci Rep. Jul 29;6:30711. doi: 10.1038/srep30711 2016
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| 12 | OLIG2
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| Molecular mechanisms of OLIG2 transcription factor in brain cancer.
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| Tsigelny IF, Kouznetsova VL, Lian N, Kesari S.
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| Oncotarget. Aug 16;7(33):53074-53101. doi: 10.18632/oncotarget.10628 2016
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| 13 | OLIG2
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| An amino terminal phosphorylation motif regulates intranuclear compartmentalization of Olig2 in neural progenitor cells.
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| Meijer DH, Sun Y, Liu T, Kane MF, Alberta JA, Adelmant G, Kupp R, Marto JA, Rowitch DH, Nakatani Y, Stiles CD, Mehta S.
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| J Neurosci 34(25):8507-18. doi: 10.1523/JNEUROSCI.0309-14.2014.
2014
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| 14 | OLIG2, PROX1
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| Prox1 regulates Olig2 expression to modulate binary fate decisions in spinal cord neurons.
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| Kaltezioti V, Antoniou D, Stergiopoulos A, Rozani I, Rohrer H, Politis PK.
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| J Neurosci 34(47):15816-31. doi: 10.1523/JNEUROSCI.1865-14.2014.
2014
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| 15 | OLIG2, TAF9B
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| Core promoter factor TAF9B regulates neuronal gene expression.
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| Herrera FJ, Yamaguchi T, Roelink H, Tjian R.
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| Elife Jul 8;3:e02559. doi: 10.7554/eLife.02559 2014
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| 16 | LGR5, OLIG2
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| LGR5 is a proneural factor and is regulated by OLIG2 in glioma stem-like cells.
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| Mao XG, Song SJ, Xue XY, Yan M, Wang L, Lin W, Guo G, Zhang X.
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| Cell Mol Neurobiol 33(6):851-65. doi: 10.1007/s10571-013-9951-6. Epub 2013 Jun 21.
2013
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| 17 | OLIG1, OLIG2
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| Stage-specific deletion of Olig2 conveys opposing functions on differentiation and maturation of oligodendrocytes.
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| Mei F, Wang H, Liu S, Niu J, Wang L, He Y, Etxeberria A, Chan JR, Xiao L.
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| J Neurosci 33(19):8454-62. doi: 10.1523/JNEUROSCI.2453-12.2013.
2013
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| 18 | OLIG2, SMARCA4
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| Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation.
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| Yu Y, Chen Y, Kim B, Wang H, Zhao C, He X, Liu L, Liu W, Wu LM, Mao M, Chan JR, Wu J, Lu QR.
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| Cell 152(1-2):248-61. doi: 10.1016/j.cell.2012.12.006.
2013
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| 19 | OLIG2
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| Olig2-dependent developmental fate switch of NG2 cells.
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| Zhu X, Zuo H, Maher BJ, Serwanski DR, LoTurco JJ, Lu QR, Nishiyama A.
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| Development 139(13):2299-307. doi: 10.1242/dev.078873. Epub 2012 May 23.
2012
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| 20 | OLIG2
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| OLIG2 over-expression impairs proliferation of human Down syndrome neural progenitors.
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| Lu J, Lian G, Zhou H, Esposito G, Steardo L, Delli-Bovi LC, Hecht JL, Lu QR, Sheen V.
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| Hum Mol Genet 21(10):2330-40. doi: 10.1093/hmg/dds052. Epub 2012 Feb 17.
2012
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| 21 | OLIG2
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| Transcription factor Olig2 defines subpopulations of retinal progenitor cells biased toward specific cell fates.
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| Hafler BP, Surzenko N, Beier KT, Punzo C, Trimarchi JM, Kong JH, Cepko CL.
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| Proc Natl Acad Sci U S A 109(20):7882-7. doi: 10.1073/pnas.1203138109. Epub 2012 Apr 27.
2012
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| 22 | MYOD1, NEUROD2, NEUROG2, OLIG2
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| Induction of motor neuron differentiation by transduction of Olig2 protein.
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| Mie M, Kaneko M, Henmi F, Kobatake E.
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| Biochem Biophys Res Commun 427(3):531-6. doi: 10.1016/j.bbrc.2012.09.090. Epub 2012 Sep 26.
2012
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| 23 | OLIG2
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| Phosphorylation regulates OLIG2 cofactor choice and the motor neuron-oligodendrocyte fate switch.
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| Li H, de Faria JP, Andrew P, Nitarska J, Richardson WD.
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| Neuron 69(5):918-29. doi: 10.1016/j.neuron.2011.01.030.
2011
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| 24 | OLIG2
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| Phosphorylation state of Olig2 regulates proliferation of neural progenitors.
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| Sun Y, Meijer DH, Alberta JA, Mehta S, Kane MF, Tien AC, Fu H, Petryniak MA, Potter GB, Liu Z, Powers JF, Runquist IS, Rowitch DH, Stiles CD.
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| Neuron 69(5):906-17. doi: 10.1016/j.neuron.2011.02.005.
2011
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| 25 | OLIG1, OLIG2, TRI21
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| Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome.
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| Chakrabarti L, Best TK, Cramer NP, Carney RS, Isaac JT, Galdzicki Z, Haydar TF.
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| Nat Neurosci 13(8):927-34. Epub 2010 Jul 18.PMID: 20639873 [ 2010
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| 26 | OLIG2
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| Positive association between OLIG2 and schizophrenia in the Chinese Han population.
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| Huang K, Tang W, Tang R, Xu Z, He Z, Li Z, Xu Y, Li X, He G, Feng G, He L, Shi Y.
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| Hum Genet 122(6):659-660. Epub 2007 Oct 13. 2008
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| 27 | ID2, OLIG2
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| Predominant expression of OLIG2 over ID2 in oligodendroglial tumors.
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| Mikami S, Hirose Y, Yoshida K, Kawase T, Ohnishi A, Nagashima K, Mukai M, Okada Y, Ikeda E.
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| Virchows Arch 450(5):575-84. Epub 2007 Mar 13.
2007
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| 28 | OLIG2
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| A crucial role for Olig2 in white matter astrocyte development.
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| Cai J, Chen Y, Cai WH, Hurlock EC, Wu H, Kernie SG, Parada LF, Lu QR.
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| Development 134(10):1887-99. Epub 2007 Apr 11.
2007
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| 29 | OLIG2
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| Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma.
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| Ligon KL, Huillard E, Mehta S, Kesari S, Liu H, Alberta JA, Bachoo RM, Kane M, Louis DN, Depinho RA, Anderson DJ, Stiles CD, Rowitch DH.
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| Neuron. 53(4):503-17. 2007
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| 30 | OLIG2, CDKN1B
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| A novel function of OLIG2 to suppress human glial tumor cell growth via p27Kip1 transactivation.
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| Tabu K, Ohnishi A, Sunden Y, Suzuki T, Tsuda M, Tanaka S, Sakai T, Nagashima K, Sawa H.
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| J Cell Sci 119(Pt 7):1433-41. 2006
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| 31 | OLIG2, POU3F3
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| The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.
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| Wissmüller S, Kosian T, Wolf M, Finzsch M, Wegner M.
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| Nucleic Acids Res 34(6):1735-44. Print 2006. 2006
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| 32 | OLIG2
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| Development of NG2 neural progenitor cells requires Olig gene function.
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| Ligon KL, Kesari S, Kitada M, Sun T, Arnett HA, Alberta JA, Anderson DJ, Stiles CD, Rowitch DH.
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| Proc Natl Acad Sci U S A. 103(20):7853-8. 2006
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| 33 | OLIG1, OLIG2, OLIG3
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| The basic helix-loop-helix olig3 establishes the neural plate boundary of the trunk and is necessary for development of the dorsal spinal cord.
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| Filippi A, Tiso N, Deflorian G, Zecchin E, Bortolussi M, Argenton F.
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| Proc Natl Acad Sci U S A 102(12):4377-82. Epub 2005 Feb 24. 2005
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| 34 | OLIG2
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| Expression pattern of the transcription factor Olig2 in response to brain injuries: implications for neuronal repair.
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| Buffo A, Vosko MR, Erturk D, Hamann GF, Jucker M, Rowitch D, Gotz M.
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| Proc Natl Acad Sci U S A 102(50):18183-8. Epub 2005 Dec 5. 2005
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| 35 | OLIG2, NEUROG2
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| Olig2 and Ngn2 function in opposition to modulate gene expression in motor neuron progenitor cells.
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| Lee SK, Lee B, Ruiz EC, Pfaff SL.
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| Genes Dev 19(2):282-94. 2005
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| 36 | OLIG2
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| Olig2 directs astrocyte and oligodendrocyte formation in postnatal subventricular zone cells.
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| Marshall CA, Novitch BG, Goldman JE.
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| J Neurosci 25(32):7289-98. 2005
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| 37 | LMO1, OLIG2
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| OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1.
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| Lin YW, Deveney R, Barbara M, Iscove NN, Nimer SD, Slape C, Aplan PD.
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| Cancer Res 65(16):7151-8.
2005
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| 38 | OLIG2
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| Negative regulatory effect of an oligodendrocytic bHLH factor OLIG2 on the astrocytic differentiation pathway.
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| Fukuda S, Kondo T, Takebayashi H, Taga T.
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| Cell Death Differ 11(2):196-202.
2004
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| 39 | OLIG2
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| Nuclear export of OLIG2 in neural stem cells is essential for ciliary neurotrophic factor-induced astrocyte differentiation.
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| Setoguchi T, Kondo T.
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| J Cell Biol. 166(7):963-8. 2004
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| 40 | OLIG1, OLIG2
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| Expression of the oligodendroglial lineage-associated markers Olig1 and Olig2 in different types of human gliomas.
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| Ohnishi A, Sawa H, Tsuda M, Sawamura Y, Itoh T, Iwasaki Y, Nagashima K.
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| J Neuropathol Exp Neurol 62(10):1052-9. 2003
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| 41 | OLIG2
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| Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex.
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| Sun T, Dong H, Wu L, Kane M, Rowitch DH, Stiles CD.
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| J Neurosci. 23(29):9547-56. 2003
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| 42 | OLIG1, OLIG2
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| Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.
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| Lu QR, Sun T, Zhu Z, Ma N, Garcia M, Stiles CD, Rowitch DH.
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| Cell 109(1):75-86. 2002
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| 43 | OLIG1, OLIG2
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| OLIG-1 and 2 gene expression and oligodendroglial tumours.
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| Hoang-Xuan K, Aguirre-Cruz L, Mokhtari K, Marie Y, Sanson M.
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| Neuropathol Appl Neurobiol 28(2):89-94. Review. 2002
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| 44 | OLIG1, OLIG2
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| The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification.
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| Zhou Q, Anderson DJ.
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| Cell. 109(1):61-73. 2002
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| 45 | OLIG1, OLIG2
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| Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors.
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| Lu QR, Park JK, Noll E, Chan JA, Alberta J, Yuk D, Alzamora MG, Louis DN, Stiles CD, Rowitch DH, Black PM.
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| Proc Natl Acad Sci U S A 98(19):10851-6. 2001
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| 46 | OLIG2
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| OLIG2 as a specific marker of oligodendroglial tumour cells.
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| Marie Y, Sanson M, Mokhtari K, Leuraud P, Kujas M, Delattre JY, Poirier J, Zalc B, Hoang-Xuan K.
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| Lancet. 358(9278):298-300. 2001
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| 47 | OLIG2
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| Combinatorial roles of olig2 and neurogenin2 in the coordinated induction of pan-neuronal and subtype-specific properties of motoneurons.
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| Mizuguchi R, Sugimori M, Takebayashi H, Kosako H, Nagao M, Yoshida S, Nabeshima Y, Shimamura K, Nakafuku M.
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| Neuron. 31(5):757-71. 2001
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| 48 | OLIG2
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| The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene.
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| Wang J, Jani-Sait SN, Escalon EA, Carroll AJ, de Jong PJ, Kirsch IR, Aplan PD.
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| Proc Natl Acad Sci U S A 97(7):3497-502. 2000
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| 49 | OLIG1, OLIG2
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| Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors.
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| Zhou Q, Wang S, Anderson DJ.
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| Neuron 25(2):331-43.PMID: 10719889 2000
|