| 1 | CLDN5, KLF4, OCLN, TJP1
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| Krüppel-like factor 4 regulates blood-tumor barrier permeability via ZO-1, occludin and claudin-5.
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| Ma J, Wang P, Liu Y, Zhao L, Li Z, Xue Y.
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| J Cell Physiol 229(7):916-26. doi: 10.1002/jcp.24523.
2014
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| 2 | BACE1, OCLN
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| Occludin deficiency with BACE1 elevation in cerebral amyloid angiopathy.
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| Cheng X, He P, Yao H, Dong Q, Li R, Shen Y.
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| Neurology 82(19):1707-15. doi: 10.1212/WNL.0000000000000403. Epub 2014 Apr 16.
2014
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| 3 | OCLN
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| Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux.
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| Buschmann MM, Shen L, Rajapakse H, Raleigh DR, Wang Y, Wang Y, Lingaraju A, Zha J, Abbott E, McAuley EM, Breskin LA, Wu L, Anderson K, Turner JR, Weber CR.
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| Mol Biol Cell 24(19):3056-68. doi: 10.1091/mbc.E12-09-0688. Epub 2013 Aug 7.
2013
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| 4 | BCPMG, OCLN
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| A novel rearrangement of occludin causes brain calcification and renal dysfunction.
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| LeBlanc MA, Penney LS, Gaston D, Shi Y, Aberg E, Nightingale M, Jiang H, Gillett RM, Fahiminiya S, Macgillivray C, Wood EP, Acott PD, Khan MN, Samuels ME, Majewski J, Orr A, McMaster CR, Bedard K.
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| Hum Genet 132(11):1223-34. doi: 10.1007/s00439-013-1327-y. Epub 2013 Jun 21.
2013
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| 5 | OCLN
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| Occludin is involved in adhesion, apoptosis, differentiation and Ca2+-homeostasis of human keratinocytes: implications for tumorigenesis.
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| Rachow S, Zorn-Kruppa M, Ohnemus U, Kirschner N, Vidal-y-Sy S, von den Driesch P, Börnchen C, Eberle J, Mildner M, Vettorazzi E, Rosenthal R, Moll I, Brandner JM.
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| PLoS One 8(2):e55116. doi: 10.1371/journal.pone.0055116. Epub 2013 Feb 4.
2013
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| 6 | CELF1, ELAVL1, OCLN
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| Competitive binding of CUGBP1 and HuR to occludin mRNA controls its translation and modulates epithelial barrier function.
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| Yu TX, Rao JN, Zou T, Liu L, Xiao L, Ouyang M, Cao S, Gorospe M, Wang JY.
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| Mol Biol Cell 24(2):85-99. doi: 10.1091/mbc.E12-07-0531. Epub 2012 Nov 14.
2013
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| 7 | MARVELD2, MARVELD3, OCLN
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| Tight junctions: Claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization.
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| Cording J, Berg J, Käding N, Bellmann C, Tscheik C, Westphal JK, Milatz S, Günzel D, Wolburg H, Piontek J, Huber O, Blasig IE.
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| J Cell Sci Cell Sci. 2012 Nov 30. [Epub ahead of print]
2012
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| 8 | NKX2-1, OCLN
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| Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1).
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| Runkle EA, Rice SJ, Qi J, Masser D, Antonetti DA, Winslow MM, Mu D.
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| J Biol Chem 287(34):28790-801. doi: 10.1074/jbc.M112.367987. Epub 2012 Jul 2.
2012
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| 9 | OCLN
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| Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function.
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| Raleigh DR, Boe DM, Yu D, Weber CR, Marchiando AM, Bradford EM, Wang Y, Wu L, Schneeberger EE, Shen L, Turner JR.
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| J Cell Biol 193(3):565-82.
2011
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| 10 | OCLN
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| Occludin localizes to centrosomes and modifies mitotic entry.
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| Runkle EA, Sundstrom JM, Runkle KB, Liu X, Antonetti DA.
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| J Biol Chem 286(35):30847-58. Epub 2011 Jul 12.
2011
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| 11 | ABCB1, OCLN, PTK2, TJP1
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| P-glycoprotein regulates blood-testis barrier dynamics via its effects on the occludin/zonula occludens 1 (ZO-1) protein complex mediated by focal adhesion kinase (FAK).
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| Su L, Mruk DD, Lui WY, Lee WM, Cheng CY.
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| Proc Natl Acad Sci U S A 108(49):19623-8. doi: 10.1073/pnas.1111414108. Epub 2011 Nov 21.
2011
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| 12 | OCLN
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| Splicing diversity of the human OCLN gene and its biological significance for hepatitis C virus entry.
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| Kohaar I, Ploss A, Korol E, Mu K, Schoggins JW, O'Brien TR, Rice CM, Prokunina-Olsson L.
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| J Virol 84(14):6987-94. Epub 2010 May 12.PMID: 20463075 2010
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| 13 | BCPMG, OCLN
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| Recessive mutations in the gene encoding the tight junction protein occludin cause band-like calcification with simplified gyration and polymicrogyria.
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| O'Driscoll MC, Daly SB, Urquhart JE, Black GC, Pilz DT, Brockmann K, McEntagart M, Abdel-Salam G, Zaki M, Wolf NI, Ladda RL, Sell S, D'Arrigo S, Squier W, Dobyns WB, Livingston JH, Crow YJ.
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| Am J Hum Genet 87(3):354-64. Epub 2010 Aug 19.PMID: 20727516 2010
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| 14 | MARVELD2, MARVELD3, OCLN
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| Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions.
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| Raleigh DR, Marchiando AM, Zhang Y, Shen L, Sasaki H, Wang Y, Long M, Turner JR.
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| Mol Biol Cell 21(7):1200-13. doi: 10.1091/mbc.E09-08-0734. Epub 2010 Feb 17. 2010
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| 15 | OCLN, PTPRJ, TJP1
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| Density-enhanced phosphatase 1 regulates phosphorylation of tight junction proteins and enhances barrier function of epithelial cells.
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| Sallee JL, Burridge K.
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| J Biol Chem 284(22):14997-5006. Epub 2009 Mar 30.
2009
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| 16 | OCLN
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| Human occludin is a hepatitis C virus entry factor required for infection of mouse cells.
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| Ploss A, Evans MJ, Gaysinskaya VA, Panis M, You H, de Jong YP, Rice CM.
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| Nature 457(7231):882-6. Epub 2009 Jan 28.PMID: 19182773 2009
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| 17 | CLDN5, OCLN
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| VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown.
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| Argaw AT, Gurfein BT, Zhang Y, Zameer A, John GR.
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| Proc Natl Acad Sci U S A 106(6):1977-82. Epub 2009 Jan 27.PMID: 19174516 2009
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| 18 | ADCY5, EFNA5, ERC2, GFPT2, GIPC2, GNA14, HSPA4L, MAGI1, MN1, MSX2, MYO5B, OCLN, RSPO1, SALL1, ZNF382
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| Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia.
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| Kuang SQ, Tong WG, Yang H, Lin W, Lee MK, Fang ZH, Wei Y, Jelinek J, Issa JP, Garcia-Manero G.
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| Leukemia 22(8):1529-38. Epub 2008 Jun 5.PMID: 18528427 2008
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| 19 | MARVELD2, OCLN
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| Loss of occludin affects tricellular localization of tricellulin.
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| Ikenouchi J, Sasaki H, Tsukita S, Furuse M, Tsukita S.
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| Mol Biol Cell 19(11):4687-93. doi: 10.1091/mbc.E08-05-0530. Epub 2008 Sep 3.
2008
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| 20 | OCLN
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| Occludin is overexpressed in Alzheimer's disease and vascular dementia.
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| Romanitan MO, Popescu BO, Winblad B, Bajenaru OA, Bogdanovic N.
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| J Cell Mol Med 11(3):569-79.
2007
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| 21 | CLDN16, OCLN, TJP1
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| Identification and subcellular localization of paracellin-1 (claudin-16) in human salivary glands.
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| Kriegs JO, Homann V, Kinne-Saffran E, Kinne RK.
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| Histochem Cell Biol 128(1):45-53. Epub 2007 Jun 6.PMID: 17551748 2007
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| 22 | OCLN, TJP1, TJP2, TJP3
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| Structure of the conserved cytoplasmic C-terminal domain of occludin: identification of the ZO-1 binding surface.
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| Li Y, Fanning AS, Anderson JM, Lavie A.
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| J Mol Biol 352(1):151-64. 2005
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| 23 | OCLN
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| Gene expression of the tight junction protein occludin includes differential splicing and alternative promoter usage.
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| Mankertz J, Waller JS, Hillenbrand B, Tavalali S, Florian P, Schoneberg T, Fromm M, Schulzke JD.
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| Biochem Biophys Res Commun 298(5):657-66. 2002
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| 24 | OCLN
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| Mammalian occludin in epithelial cells : its expression and subcellular distribution.
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| Saitou M, et al.
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| Eur J Cell Biol 73 : 222-231. 1997
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| 25 | OCLN
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| Interspecies diversity of the occludin sequence : cDNA cloning of human, mouse, dog, and rat-kangaroo homologues.
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| Ando-Akatsuka Y, et al.
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| J Cell Biol 133 : 43-47. 1996
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