| 1 | OBSCN
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| Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis.
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| Shriver M, Stroka KM, Vitolo MI, Martin S, Huso DL, Konstantopoulos K, Kontrogianni-Konstantopoulos A.
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| Oncogene ncogene. 2014 Nov 10. doi: 10.1038/onc.2014.358. [Epub ahead of print]
2014
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| 2 | OBSCN
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| Obscurins: Goliaths and Davids take over non-muscle tissues.
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| Ackermann MA, Shriver M, Perry NA, Hu LY, Kontrogianni-Konstantopoulos A.
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| PLoS One 9(2):e88162. doi: 10.1371/journal.pone.0088162. eCollection 2014.
2014
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| 3 | ANK2, OBSCN
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| Obscurin is required for ankyrinB-dependent dystrophin localization and sarcolemma integrity.
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| Randazzo D, Giacomello E, Lorenzini S, Rossi D, Pierantozzi E, Blaauw B, Reggiani C, Lange S, Peter AK, Chen J, Sorrentino V.
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| J Cell Biol 200(4):523-36. doi: 10.1083/jcb.201205118.
2013
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| 4 | OBSCN
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| The kinase domains of obscurin interact with intercellular adhesion proteins.
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| Hu LY, Kontrogianni-Konstantopoulos A.
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| FASEB J 27(5):2001-12. doi: 10.1096/fj.12-221317. Epub 2013 Feb 7.
2013
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| 5 | KCTD6, OBSCN
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| Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover.
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| Lange S, Perera S, Teh P, Chen J.
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| Mol Biol Cell 23(13):2490-504. doi: 10.1091/mbc.E12-01-0052. Epub 2012 May 9.
2012
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| 6 | ANK1, OBSCN
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| Characterization and comparison of two binding sites on obscurin for small ankyrin 1.
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| Busby B, Willis CD, Ackermann MA, Kontrogianni-Konstantopoulos A, Bloch RJ.
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| Biochemistry 49(46):9948-56. Epub 2010 Nov 1.
2010
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| 7 | CDC42, OBSCN, RAC1, RHOQ, TCP10
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| TC10 controls human myofibril organization and is activated by the sarcomeric RhoGEF obscurin.
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| Coisy-Quivy M, Touzet O, Bourret A, Hipskind RA, Mercier J, Fort P, Philips A.
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| J Cell Sci 122(Pt 7):947-56. Epub 2009 Mar 3. 2009
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| 8 | OBSCN
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| The rho-guanine nucleotide exchange factor domain of obscurin activates rhoA signaling in skeletal muscle.
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| Ford-Speelman DL, Roche JA, Bowman AL, Bloch RJ.
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| Mol Biol Cell 20(17):3905-17. Epub 2009 Jul 15.
2009
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| 9 | ANK2, OBSCN
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| Oxidized calmodulin kinase II regulates conduction following myocardial infarction: a computational analysis.
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| Christensen MD, Dun W, Boyden PA, Anderson ME, Mohler PJ, Hund TJ.
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| PLoS Comput Biol 5(12):e1000583. Epub 2009 Dec 4.
2009
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| 10 | OBSCN, TTN
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| Muscle giants: molecular scaffolds in sarcomerogenesis.
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| Kontrogianni-Konstantopoulos A, Ackermann MA, Bowman AL, Yap SV, Bloch RJ.
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| Physiol Rev 89(4):1217-67. Review.
2009
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| 11 | OBSCN
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| Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum.
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| Lange S, Ouyang K, Meyer G, Cui L, Cheng H, Lieber RL, Chen J.
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| J Cell Sci 122(Pt 15):2640-50. Epub 2009 Jul 7.
2009
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| 12 | MYBPC1, OBSCN
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| Obscurin interacts with a novel isoform of MyBP-C slow at the periphery of the sarcomeric M-band and regulates thick filament assembly.
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| Ackermann MA, Hu LY, Bowman AL, Bloch RJ, Kontrogianni-Konstantopoulos A.
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| Mol Biol Cell 20(12):2963-78. Epub 2009 Apr 29.
2009
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| 13 | ANK2, OBSCN
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| Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line.
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| Cunha SR, Mohler PJ.
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| J Biol Chem 283(46):31968-80. Epub 2008 Sep 9.
2008
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| 14 | OBSCN
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| Different obscurin isoforms localize to distinct sites at sarcomeres.
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| Bowman AL, Kontrogianni-Konstantopoulos A, Hirsch SS, Geisler SB, Gonzalez-Serratos H, Russell MW, Bloch RJ.
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| FEBS Lett 581(8):1549-54. Epub 2007 Mar 15. 2007
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| 15 | OBSL1, SPEG, OBSCN
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| Obscurin-like 1, OBSL1, is a novel cytoskeletal protein related to obscurin.
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| Geisler SB, Robinson D, Hauringa M, Raeker MO, Borisov AB, Westfall MV, Russell MW.
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| Genomics 89(4):521-31. Epub 2007 Feb 6. 2007
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| 16 | OBSCN, ANK1
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| Mapping the binding site on small ankyrin 1 for obscurin.
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| Borzok MA, Catino DH, Nicholson JD, Kontrogianni-Konstantopoulos A, Bloch RJ.
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| J Biol Chem 282(44):32384-96. Epub 2007 Aug 25. 2007
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| 17 | OBSCN, ANK1
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| Molecular interactions with obscurin are involved in the localization of muscle-specific small ankyrin1 isoforms to subcompartments of the sarcoplasmic reticulum.
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| Armani A, Galli S, Giacomello E, Bagnato P, Barone V, Rossi D, Sorrentino V.
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| Exp Cell Res 312(18):3546-58. Epub 2006 Aug 16. 2006
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| 18 | OBSCN
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| Complete human gene structure of obscurin: implications for isoform generation by differential splicing.
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| Fukuzawa A, Idowu S, Gautel M.
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| J Muscle Res Cell Motil 26(6-8):427-34. 2005
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| 19 | OBSCN
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| Obscurin regulates the organization of myosin into A bands.
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| Kontrogianni-Konstantopoulos A, Catino DH, Strong JC, Randall WR, Bloch RJ.
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| Am J Physiol Cell Physiol 287(1):C209-17. Epub 2004 Mar 10. 2004
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| 20 | OBSCN, ANK1
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| Obscurin is a ligand for small ankyrin 1 in skeletal muscle.
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| Kontrogianni-Konstantopoulos A, Jones EM, Van Rossum DB, Bloch RJ.
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| Mol Biol Cell 14(3):1138-48. 2003
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| 21 | OBSCN
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| Identification, tissue expression and chromosomal localization of human Obscurin-MLCK, a member of the titin and Dbl families of myosin light chain kinases.
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| Russell MW, Raeker MO, Korytkowski KA, Sonneman KJ.
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| Gene 282(1-2):237-46. 2002
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| 22 | OBSCN
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| Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly.
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| Young P, Ehler E, Gautel M.
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| J Cell Biol 154(1):123-36. 2001
|