| 1 | NDC80, NUF2, SPC24, SPC25
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| Ectopic expression of plasma membrane targeted subunits of the Ndc80-complex as a tool to study kinetochore biochemistry.
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| Holmström TH, Rehnberg J, Ahonen LJ, Kallio MJ.
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| Mol Oncol ol Oncol. 2009 Feb 21. [Epub ahead of print]PMID: 19393581 2009
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| 2 | NDC80, NUF2, SPC24, SPC25
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| siRNA-mediated knockdown against CDCA1 and KNTC2, both frequently overexpressed in colorectal and gastric cancers, suppresses cell proliferation and induces apoptosis.
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| Kaneko N, Miura K, Gu Z, Karasawa H, Ohnuma S, Sasaki H, Tsukamoto N, Yokoyama S, Yamamura A, Nagase H, Shibata C, Sasaki I, Horii A.
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| Biochem Biophys Res Commun 390(4):1235-40. Epub 2009 Oct 28.PMID: 19878654 2009
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| 3 | NDC80, NUF2, SPC24, SPC25
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| Orientation and structure of the Ndc80 complex on the microtubule lattice.
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| Wilson-Kubalek EM, Cheeseman IM, Yoshioka C, Desai A, Milligan RA.
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| J Cell Biol 182(6):1055-61. Epub 2008 Sep 15.PMID: 18794333 2008
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| 4 | NUF2, CENPE
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| Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachment.
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| Liu D, Ding X, Du J, Cai X, Huang Y, Ward T, Shaw A, Yang Y, Hu R, Jin C, Yao X.
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| J Biol Chem 282(29):21415-24. Epub 2007 May 29. 2007
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| 5 | NDC80, NUF2
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| Activation of CDCA1-KNTC2, members of centromere protein complex, involved in pulmonary carcinogenesis.
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| Hayama S, Daigo Y, Kato T, Ishikawa N, Yamabuki T, Miyamoto M, Ito T, Tsuchiya E, Kondo S, Nakamura Y.
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| Cancer Res 66(21):10339-48.
2006
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| 6 | NDC80, NUF2, SPC24, SPC25
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| Structure of a central component of the yeast kinetochore: the Spc24p/Spc25p globular domain.
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| Wei RR, Schnell JR, Larsen NA, Sorger PK, Chou JJ, Harrison SC.
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| Structure 14(6):1003-9.PMID: 16765893 2006
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| 7 | NUF2
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| Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites.
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| DeLuca JG, Dong Y, Hergert P, Strauss J, Hickey JM, Salmon ED, McEwen BF.
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| Mol Biol Cell 16(2):519-31. Epub 2004 Nov 17. 2005
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| 8 | NDC80, NUF2, SPC24, SPC25
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| Architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochore.
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| Ciferri C, De Luca J, Monzani S, Ferrari KJ, Ristic D, Wyman C, Stark H, Kilmartin J, Salmon ED, Musacchio A.
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| J Biol Chem 280(32):29088-95. Epub 2005 Jun 16.PMID: 15961401 2005
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| 9 | NDC80, NUF2, SPC24, SPC25
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| The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment.
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| McCleland ML, Kallio MJ, Barrett-Wilt GA, Kestner CA, Shabanowitz J, Hunt DF, Gorbsky GJ, Stukenberg PT.
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| Curr Biol 14(2):131-7.PMID: 14738735 2004
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| 10 | NUF2
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| hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells.
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| DeLuca JG, Moree B, Hickey JM, Kilmartin JV, Salmon ED.
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| J Cell Biol 159(4):549-55. Epub 2002 Nov 18. 2002
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| 11 | NUF2
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| A conserved protein, Nuf2, is implicated in connecting the centromere to the spindle during chromosome segregation: a link between the kinetochore function and the spindle checkpoint.
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| Nabetani A, Koujin T, Tsutsumi C, Haraguchi T, Hiraoka Y.
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| Chromosoma 110(5):322-34. 2001
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| 12 | NUF2
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| The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation.
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| Wigge PA, Kilmartin JV.
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| J Cell Biol 152(2):349-60. 2001
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