| 1 | ANXA2, LIMK2, NUDT21
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| NUDT21 inhibits bladder cancer progression through ANXA2 and LIMK2 by alternative polyadenylation.
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| Xiong M, Chen L, Zhou L, Ding Y, Kazobinka G, Chen Z, Hou T.
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| Theranostics 9(24):7156-7167. doi: 10.7150/thno.36030. eCollection 2019.
2019
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| 2 | EZH2, NUDT21
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| The role of NUDT21 in microRNA-binging sites of EZH2 gene increases the of risk preeclampsia.
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| Lang X, Zhao W, Huang D, Liu W, Shen H, Xu L, Xu S, Huang Y, Cheng W.
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| J Cell Mol Med 23(5):3202-3213. doi: 10.1111/jcmm.14179. Epub 2019 Mar 18.
2019
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| 3 | NUDT21, pAK1
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| Nudt21 regulates the alternative polyadenylation of Pak1 and is predictive in the prognosis of glioblastoma patients.
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| Chu Y, Elrod N, Wang C, Li L, Chen T, Routh A, Xia Z, Li W, Wagner EJ, Ji P.
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| Oncogene 38(21):4154-4168. doi: 10.1038/s41388-019-0714-9. Epub 2019 Jan 31.
2019
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| 4 | CXXC5, NUDT21, PSMB2
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| NUDT21 negatively regulates PSMB2 and CXXC5 by alternative polyadenylation and contributes to hepatocellular carcinoma suppression.
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| Tan S, Li H, Zhang W, Shao Y, Liu Y, Guan H, Wu J, Kang Y, Zhao J, Yu Q, Gu Y, Ding K, Zhang M, Qian W, Zhu Y, Cai H, Chen C, Lobie PE, Zhao X, Sun J, Zhu T.
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| Oncogene 37(35):4887-4900. doi: 10.1038/s41388-018-0280-6. Epub 2018 May 21.
2018
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| 5 | NUDT21
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| Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling.
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| Brumbaugh J, Di Stefano B, Wang X, Borkent M, Forouzmand E, Clowers KJ, Ji F, Schwarz BA, Kalocsay M, Elledge SJ, Chen Y, Sadreyev RI, Gygi SP, Hu G, Shi Y, Hochedlinger K.
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| Cell 172(3):629-631. doi: 10.1016/j.cell.2017.12.035. No abstract available.
2018
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| 6 | MECP2, NUDT21
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| NUDT21-spanning CNVs lead to neuropsychiatric disease and altered MeCP2 abundance via alternative polyadenylation.
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| Gennarino VA, Alcott CE, Chen CA, Chaudhury A, Gillentine MA, Rosenfeld JA, Parikh S, Wheless JW, Roeder ER, Horovitz DD, Roney EK, Smith JL, Cheung SW, Li W, Neilson JR, Schaaf CP, Zoghbi HY.
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| Elife 4. doi: 10.7554/eLife.10782.
2015
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| 7 | NUDT21
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| The crystal structure of human cleavage and polyadenylation specific factor-5 reveals a dimeric Nudix protein with a conserved catalytic site.
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| Trésaugues L, Stenmark P, Schüler H, Flodin S, Welin M, Nyman T, Hammarström M, Moche M, Gräslund S, Nordlund P.
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| Proteins 73(4):1047-52. doi: 10.1002/prot.22198. No abstract available.
2008
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| 8 | CPSF6, NUDT21
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| Pre-messenger RNA cleavage factor I (CFIm): potential role in alternative polyadenylation during spermatogenesis.
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| Sartini BL, Wang H, Wang W, Millette CF, Kilpatrick DL.
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| Biol Reprod 78(3):472-82. Epub 2007 Nov 21.
2008
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| 9 | CPSF6, NUDT21, SRSF3, TRA2B
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| Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization.
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| Dettwiler S, Aringhieri C, Cardinale S, Keller W, Barabino SM.
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| J Biol Chem 279(34):35788-97. Epub 2004 May 28. 2004
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| 10 | NUDT21
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| Interaction of poly(A) polymerase with the 25-kDa subunit of cleavage factor I.
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| Kim H, Lee Y.
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| Biochem Biophys Res Commun 289(2):513-8. 2001
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| 11 | NUDT21, CPSF6
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| Human pre-mRNA cleavage factor Im is related to spliceosomal SR proteins and can be reconstituted in vitro from recombinant subunits.
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| Ruegsegger U, Blank D, Keller W.
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| Mol Cell 1(2):243-53. 1998
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| 12 | CPSF6, CSTF1, NUDT21
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| Purification and characterization of human cleavage factor Im involved in the 3' end processing of messenger RNA precursors.
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| Rüegsegger U, Beyer K, Keller W.
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| J Biol Chem 271(11):6107-13.
1996
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