| 1 | NTRK3, PLEKHA6
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| A novel fusion gene PLEKHA6-NTRK3 in langerhans cell histiocytosis.
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| Cai J, Huang X, Yin M, Pan C, Song L, Zhan Z, Chen J, Gao Y, Tang J, Li Y, Shen S.
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| Int J Cancer nt J Cancer. 2018 Aug 11. doi: 10.1002/ijc.31636. [Epub ahead of print]
2018
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| 2 | NTRK3, RUNX3
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| Runx3-regulated expression of two Ntrk3 transcript variants in dorsal root ganglion neurons.
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| Ogihara Y, Masuda T, Ozaki S, Yoshikawa M, Shiga T.
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| Dev Neurobiol 76(3):313-22. doi: 10.1002/dneu.22316.
2016
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| 3 | LINGO1, NTRK1, NTRK2, NTRK3
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| Intracellular LINGO-1 negatively regulates Trk neurotrophin receptor signaling.
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| Meabon JS, de Laat R, Ieguchi K, Serbzhinsky D, Hudson MP, Huber BR, Wiley JC, Bothwell M.
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| Mol Cell Neurosci 70:1-10. doi: 10.1016/j.mcn.2015.11.002. Epub 2015 Nov 3.
2016
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| 4 | NTRK2, NTRK3
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| Neurotrophin signaling via TrkB and TrkC receptors promotes the growth of brain tumor-initiating cells.
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| Lawn S, Krishna N, Pisklakova A, Qu X, Fenstermacher DA, Fournier M, Vrionis FD, Tran N, Chan JA, Kenchappa RS, Forsyth PA.
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| J Biol Chem 290(6):3814-24. doi: 10.1074/jbc.M114.599373. Epub 2014 Dec 23.
2015
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| 5 | LRP1, NTRK3
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| Low-density lipoprotein receptor-related protein 1 (LRP1)-dependent cell signaling promotes axonal regeneration.
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| Yoon C, Van Niekerk EA, Henry K, Ishikawa T, Orita S, Tuszynski MH, Campana WM.
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| J Biol Chem 288(37):26557-68. doi: 10.1074/jbc.M113.478552. Epub 2013 Jul 18.
2013
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| 6 | NTRK3
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| Dependence receptor TrkC is a putative colon cancer tumor suppressor.
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| Genevois AL, Ichim G, Coissieux MM, Lambert MP, Lavial F, Goldschneider D, Jarrosson-Wuilleme L, Lepinasse F, Gouysse G, Herceg Z, Scoazec JY, Tauszig-Delamasure S, Mehlen P.
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| Proc Natl Acad Sci U S A 110(8):3017-22. doi: 10.1073/pnas.1212333110. Epub 2013 Jan 22.
2013
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| 7 | NELFB, NTF3, NTRK3
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| The dependence receptor TrkC triggers mitochondria-dependent apoptosis upon Cobra-1 recruitment.
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| Ichim G, Genevois AL, Ménard M, Yu LY, Coelho-Aguiar JM, Llambi F, Jarrosson-Wuilleme L, Lefebvre J, Tulasne D, Dupin E, Le Douarin N, Arumäe U, Tauszig-Delamasure S, Mehlen P.
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| Mol Cell 51(5):632-46. doi: 10.1016/j.molcel.2013.08.021. 2013
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| 8 | NTRK3
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| NTRK3 is a potential tumor suppressor gene commonly inactivated by epigenetic mechanisms in colorectal cancer.
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| Luo Y, Kaz AM, Kanngurn S, Welsch P, Morris SM, Wang J, Lutterbaugh JD, Markowitz SD, Grady WM.
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| PLoS Genet 9(7):e1003552. doi: 10.1371/journal.pgen.1003552. Epub 2013 Jul 11.
2013
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| 9 | NTRK3
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| TrkC promotes survival and growth of leukemia cells through Akt-mTOR-dependent up-regulation of PLK-1 and Twist-1.
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| Kim MS, Kim GM, Choi YJ, Kim HJ, Kim YJ, Jin W.
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| Mol Cells 36(2):177-84. doi: 10.1007/s10059-013-0061-6. Epub 2013 Jul 4.
2013
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| 10 | NEUROD1, NTRK2, NTRK3
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| NeuroD regulates neuronal migration.
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| Kim WY.
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| Mol Cells 35(5):444-9. doi: 10.1007/s10059-013-0065-2. Epub 2013 May 6.
2013
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| 11 | NTRK3, SOX2
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| Transcriptional regulation of TRKC by SOX2 in human embryonic stem cells.
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| Fong H, Wong RC, Donovan PJ.
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| Stem Cell Res 8(2):206-14. doi: 10.1016/j.scr.2011.10.003. Epub 2011 Oct 26.
2012
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| 12 | CYLD, NTRK2, NTRK3
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| Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours.
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| Rajan N, Elliott R, Clewes O, Mackay A, Reis-Filho JS, Burn J, Langtry J, Sieber-Blum M, Lord CJ, Ashworth A.
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| Oncogene 30(41):4243-60. doi: 10.1038/onc.2011.133. Epub 2011 May 9.
2011
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| 13 | NTF3, NTRK3
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| Neurotrophin-3 and tyrosine kinase C have modulatory effects on neuropathic pain in the rat dorsal root ganglia.
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| Tender GC, Kaye AD, Li YY, Cui JG.
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| Neurosurgery 68(4):1048-55; discussion 1055. doi: 10.1227/NEU.0b013e318208f9c4.
2011
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| 14 | NTRK1, NTRK2, NTRK3
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| Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not.
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| Nikoletopoulou V, Lickert H, Frade JM, Rencurel C, Giallonardo P, Zhang L, Bibel M, Barde YA.
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| Nature 467(7311):59-63. 2010
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| 15 | NTRK3
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| Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders.
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| Muiños-Gimeno M, Guidi M, Kagerbauer B, Martín-Santos R, Navinés R, Alonso P, Menchón JM, Gratacòs M, Estivill X, Espinosa-Parrilla Y.
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| Hum Mutat 30(7):1062-71.PMID: 19370765 2009
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| 16 | NTRK3
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| Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia.
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| Otnaess MK, Djurovic S, Rimol LM, Kulle B, Kähler AK, Jönsson EG, Agartz I, Sundet K, Hall H, Timm S, Hansen T, Callicott JH, Melle I, Werge T, Andreassen OA.
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| Neurobiol Dis 34(3):518-24. Epub 2009 Mar 31.PMID: 19344762 2009
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| 17 | NTRK3
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| Neurotrophin 3/TrkC-regulated proteins in the human medulloblastoma cell line DAOY.
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| Gruber-Olipitz M, Ströbel T, Kang SU, John JP, Grotzer MA, Slavc I, Lubec G.
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| Electrophoresis 30(3):540-9.PMID: 19156760 2009
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| 18 | NGF, NTRK3
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| Association of NTRK3 and its interaction with NGF suggest an altered cross-regulation of the neurotrophin signaling pathway in eating disorders.
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| Mercader JM, Saus E, AgŸera Z, BayŽs M, Boni C, Carreras A, Cellini E, de Cid R, Dierssen M, Escaram’s G, Fern‡ndez-Aranda F, Forcano L, Gallego X, Gonz‡lez JR, Gorwood P, Hebebrand J, Hinney A, Nacmias B, Puig A, RibasŽs M, Ricca V, Romo L, Sorbi S, Versini A, Gratac˜s M, Estivill X.
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| Hum Mol Genet 17(9):1234-44. Epub 2008 Jan 18. 2008
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| 19 | NTRK3
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| Linkage disequilibrium mapping of a chromosome 15q25-26 major depression linkage region and sequencing of NTRK3.
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| Verma R, Holmans P, Knowles JA, Grover D, Evgrafov OV, Crowe RR, Scheftner WA, Weissman MM, DePaulo JR Jr, Potash JB, Levinson DF.
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| Biol Psychiatry 63(12):1185-9. Epub 2008 Mar 25.PMID: 18367154 2008
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| 20 | NTRK3
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| The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas.
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| Perez-Pinera P, Hernandez T, Garcia-Suarez O, de Carlos F, Germana A, Del Valle M, Astudillo A, Vega JA.
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| Mol Cell Biochem 295(1-2):19-26. Epub 2006 Jul 22. 2007
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| 21 | EPHA3, NTRK3, GUCY2F
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| Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers.
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| Wood LD, Calhoun ES, Silliman N, Ptak J, Szabo S, Powell SM, Riggins GJ, Wang TL, Yan H, Gazdar A, Kern SE, Pennacchio L, Kinzler KW, Vogelstein B, Velculescu VE.
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| Hum Mutat 27(10):1060-1. 2006
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| 22 | NTRK3, NTF3
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| Human scalp skin and hair follicles express neurotrophin-3 and its high-affinity receptor tyrosine kinase C, and show hair cycle-dependent alterations in expression.
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| Adly MA, Assaf HA, Nada EA, Soliman M, Hussein M.
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| Br J Dermatol 153(3):514-20. 2005
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| 23 | SH2D1A, NTRK1, NTRK2, NTRK3
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| SLAM-associated protein as a potential negative regulator in Trk signaling.
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| Lo KY, Chin WH, Ng YP, Cheng AW, Cheung ZH, Ip NY.
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| J Biol Chem 280(50):41744-52. Epub 2005 Oct 13. 2005
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| 24 | ETV6, NTRK3
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| A highly conserved NTRK3 C-terminal sequence in the ETV6-NTRK3 oncoprotein binds the phosphotyrosine binding domain of insulin receptor substrate-1: an essential interaction for transformation.
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| Lannon CL, Martin MJ, Tognon CE, Jin W, Kim SJ, Sorensen PH.
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| J Biol Chem 279(8):6225-34. Epub 2003 Dec 9. 2004
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| 25 | BDNF, NTRK2, NTRK3
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| Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons.
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| Postigo A, Calella AM, Fritzsch B, Knipper M, Katz D, Eilers A, Schimmang T, Lewin GR, Klein R, Minichiello L.
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| Genes Dev 16(5):633-45. 2002
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| 26 | ETV6, NTRK3
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| Cryptic t(12;15)(p13;q26) producing the ETV6-NTRK3 fusion gene and no loss of IGF2 imprinting in congenital mesoblastic nephroma with trisomy 11: fluorescence in situ hybridization and IGF2 allelic expression analysis.
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| Watanabe N, Kobayashi H, Hirama T, Kikuta A, Koizumi S, Tsuru T, Kaneko Y.
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| Cancer Genet Cytogenet 136(1):10-6. 2002
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| 27 | NTRK2, NTRK3
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| Mutation analysis of NTRK2 and NTRK3, encoding 2 tyrosine kinase receptors, in sporadic human medullary thyroid carcinoma reveals novel sequence variants.
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| Gimm O, Dziema H, Brown J, de la Puente A, Hoang-Vu C, Dralle H, Plass C, Eng C.
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| Int J Cancer 92(1):70-4. 2001
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| 28 | ETV6, NTRK3
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| A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma.
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| Knezevich SR, McFadden DE, Tao W, Lim JF, Sorensen PH.
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| Nat Genet 18(2):184-7. 1998
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| 29 | NTRK3
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| Genomic characterization of the human trkC gene.
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| Ichaso N, et al.
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| Oncogene 17 : 1871-1875. 1998
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| 30 | ETV6, NTRK3
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| Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion : cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma.
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| Rubin BP, et al.
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| Am J Pathol 153 : 1451-1458. 1998
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| 31 | NTRK1, NTRK2, NTRK3
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| Mapping of the tyrosine kinase receptors trkA(NTRK1),trkB (NTRK2) and trkC (NTRK3) to human chromosomes 1q22, 9q22 and 15q25 by fluorescence in situ hybridization.
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| Valent A, Danglot G, Bernheim A.
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| Eur J Hum Genet 5(2):102-4. 1997
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| 32 | NTRK3
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| Naturally occurring tyrosine kinase inserts block high affinity binding of phospholipase C gamma and Shc to TrkC and neurotrophin-3 signaling.
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| Guiton M, Gunn-Moore FJ, Glass DJ, Geis DR, Yancopoulos GD, Tavaré JM.
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| J Biol Chem 270(35):20384-90.PMID: 7657612 1995
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| 33 | NTRK3
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| Molecular cloning of the cDNA for human TrkC (NTRK3), chromosomal assignment, and evidence for a splice variant.
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| McGregor LM, et al.
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| Genomics 22 : 267-272. 1994
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| 34 | NTRK3
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| Structure and expression of the Tyro 10 receptor tyrosine kinase.
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| Lai C, et al.
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| Oncogene 9(3):877-83 1994
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| 35 | NTRK3
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| trkC, a receptor for neurodrophin-3, is widely expressed in the developing nervous system and in non-neuronal tissues.
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| Tessarollo L, et al.
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| Development 118 : 463-475. 1993
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