| 1 | NTN1, UNC5A, UNC5B, UNC5C, UNC5D
|
| Growth cone repulsion to Netrin-1 depends on lipid raft microdomains enriched in UNC5 receptors.
|
| Hernaiz-Llorens M, Roselló-Busquets C, Durisic N, Filip A, Ulloa F, Martínez-Mármol R, Soriano E.
|
| Cell Mol Life Sci. Mar;78(6):2797-2820. doi: 10.1007/s00018-020-03663-z. Epub 2020 Oct 23. 2021
|
| 2 | NTN1, TUBB3, UNC5C
|
| Disease-associated mutations in human TUBB3 disturb netrin repulsive signaling.
|
| Shao Q, Yang T, Huang H, Majumder T, Khot BA, Khouzani MM, Alarmanazi F, Gore YK, Liu G.
|
| PLoS One. Jun 21;14(6):e0218811. doi: 10.1371/journal.pone.0218811. 2019
|
| 3 | DCC, NTN1, TUBB3
|
| Human TUBB3 Mutations Disrupt Netrin Attractive Signaling
|
| Huang H, Yang T, Shao Q, Majumder T, Mell K, Liu G.
|
| Neuroscience. Mar 15;374:155-171. doi: 10.1016/j.neuroscience.2018.01.046. Epub 2018 Jan 31. 2018
|
| 4 | NTN1, TUBB3, UNC5C
|
| Uncoupling of UNC5C with Polymerized TUBB3 in Microtubules Mediates Netrin-1 Repulsion.
|
| Shao Q, Yang T, Huang H, Alarmanazi F, Liu G.
|
| J Neurosci. Jun 7;37(23):5620-5633. doi: 10.1523/JNEUROSCI.2617-16.2017. Epub 2017 May 8. 2017
|
| 5 | NAA10, NTN1, UNC5B
|
| Unc-5 homolog B (UNC5B) is one of the key downstream targets of N-α-Acetyltransferase 10 (Naa10).
|
| Xu H, Han Y, Liu B, Li R.
|
| Sci Rep 6:38508. doi: 10.1038/srep38508.
2016
|
| 6 | DCC, NTN1, UNC5C
|
| Unc5C and DCC act downstream of Ctip2 and Satb2 and contribute to corpus callosum formation.
|
| Srivatsa S, Parthasarathy S, Britanova O, Bormuth I, Donahoo AL, Ackerman SL, Richards LJ, Tarabykin V.
|
| Nat Commun 5:3708. doi: 10.1038/ncomms4708.
2014
|
| 7 | DCC, NTN1, UNC5C
|
| Netrin 1 and Dcc signalling are required for confinement of central axons within the central nervous system.
|
| Laumonnerie C, Da Silva RV, Kania A, Wilson SI.
|
| Development 141(3):594-603. doi: 10.1242/dev.099606.
2014
|
| 8 | GAP43, NTN1
|
| GAP-43 dependency defines distinct effects of netrin-1 on cortical and spinal neurite outgrowth and directional guidance.
|
| Shen Y, Meiri K.
|
| Int J Dev Neurosci 31(1):11-20. doi: 10.1016/j.ijdevneu.2012.10.006. Epub 2012 Oct 17.
2013
|
| 9 | DCC, DSCAM, MAPK8, NTN1, UNC5C
|
| c-Jun N-terminal kinase 1 (JNK1) is required for coordination of netrin signaling in axon guidance.
|
| Qu C, Li W, Shao Q, Dwyer T, Huang H, Yang T, Liu G.
|
| J Biol Chem 288(3):1883-95. doi: 10.1074/jbc.M112.417881. Epub 2012 Dec 6.
2013
|
| 10 | DCC, DSCAM, NTN1, UNC5C
|
| Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse.
|
| Purohit AA, Li W, Qu C, Dwyer T, Shao Q, Guan KL, Liu G.
|
| J Biol Chem 287(32):27126-38. doi: 10.1074/jbc.M112.340174. Epub 2012 Jun 8.
2012
|
| 11 | NTN1, UNC5B
|
| Netrin-1 simultaneously suppresses corneal inflammation and neovascularization.
|
| Han Y, Shao Y, Lin Z, Qu YL, Wang H, Zhou Y, Chen W, Chen Y, Chen WL, Hu FR, Li W, Liu Z.
|
| Invest Ophthalmol Vis Sci. Mar 9;53(3):1285-95. doi: 10.1167/iovs.11-8722. 2012
|
| 12 | NTN1
|
| Netrin1 is required for neural and glial precursor migrations into the olfactory bulb.
|
| Hakanen J, Duprat S, Salminen M.
|
| Dev Biol 355(1):101-14. Epub 2011 Apr 23.
2011
|
| 13 | NTN1
|
| Intracellular kinases mediate increased translation and secretion of netrin-1 from renal tubular epithelial cells.
|
| Jayakumar C, Mohamed R, Ranganathan PV, Ramesh G.
|
| PLoS One 6(10):e26776. Epub 2011 Oct 26.
2011
|
| 14 | NTN1
|
| Netrin-1 overexpression is predictive of ovarian malignancies.
|
| Papanastasiou AD, Pampalakis G, Katsaros D, Sotiropoulou G.
|
| Oncotarget 2(5):363-7.
2011
|
| 15 | NTN1
|
| Reduced expression of netrin-1 is associated with fetal growth restriction.
|
| Qian-hua W, Shao-ping Z, Jian-wen Z, Yun Y, Li Z.
|
| Mol Cell Biochem 350(1-2):81-7. Epub 2010 Dec 31.
2011
|
| 16 | NTN1
|
| Slit and Netrin-1 guide cranial motor axon pathfinding via Rho-kinase, myosin light chain kinase and myosin II.
|
| Murray A, Naeem A, Barnes SH, Drescher U, Guthrie S.
|
| Neural Dev 5:16.
2010
|
| 17 | NTN1
|
| Netrin-1, a missing link between chronic inflammation and tumor progression.
|
| Paradisi A, Mehlen P.
|
| Cell Cycle 9(7):1253-62.
2010
|
| 18 | NTN1, UNC5A, UNC5B, UNC5C, UNC5D
|
| Netrin-1 up-regulation in inflammatory bowel diseases is required for colorectal cancer progression.
|
| Paradisi A, Maisse C, Coissieux MM, Gadot N, Lépinasse F, Delloye-Bourgeois C, Delcros JG, Svrcek M, Neufert C, Fléjou JF, Scoazec JY, Mehlen P.
|
| Proc Natl Acad Sci U S A 106(40):17146-51. Epub 2009 Aug 31.PMID: 19721007 2009
|
| 19 | DOCK1, NTN1
|
| Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signaling.
|
| Li X, Gao X, Liu G, Xiong W, Wu J, Rao Y.
|
| Nat Neurosci 11(1):28-35. Epub 2007 Dec 9. 2008
|
| 20 | DCC, NTN1
|
| The dependence receptor DCC requires lipid raft localization for cell death signaling.
|
| Furne C, Corset V, Herincs Z, Cahuzac N, Hueber AO, Mehlen P.
|
| Proc Natl Acad Sci U S A 103(11):4128-33. Epub 2006 Mar 6. 2006
|
| 21 | NTN1, PITPNA
|
| Phosphatidylinositol transfer protein-alpha in netrin-1-induced PLC signalling and neurite outgrowth.
|
| Xie Y, Ding YQ, Hong Y, Feng Z, Navarre S, Xi CX, Zhu XJ, Wang CL, Ackerman SL, Kozlowski D, Mei L, Xiong WC.
|
| Nat Cell Biol 7(11):1124-32.
2005
|
| 22 | NTN1, UNC5A, UNC5B, UNC5C, UNC5D
|
| Netrin-1 controls colorectal tumorigenesis by regulating apoptosis.
|
| Mazelin L, Bernet A, Bonod-Bidaud C, Pays L, Arnaud S, Gespach C, Bredesen DE, Scoazec JY, Mehlen P.
|
| Nature 431(7004):80-4. 2004
|
| 23 | NTN1
|
| Netrin 1-mediated chemoattraction regulates the migratory pathway of LHRH neurons.
|
| Schwarting GA, Raitcheva D, Bless EP, Ackerman SL, Tobet S.
|
| Eur J Neurosci 19(1):11-20. 2004
|
| 24 | NTN1, SHH
|
| The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance.
|
| Charron F, Stein E, Jeong J, McMahon AP, Tessier-Lavigne M.
|
| Cell 113(1):11-23. 2003
|
| 25 | DCC, MAPK1, MAPK3, NTN1
|
| Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation.
|
| Forcet C, Stein E, Pays L, Corset V, Llambi F, Tessier-Lavigne M, Mehlen P.
|
| Nature 417(6887):443-7. 2002
|
| 26 | NTN1
|
| Identification of domains of netrin UNC-6 that mediate attractive and repulsive guidance and responses from cells and growth cones.
|
| Lim YS, Wadsworth WG.
|
| J Neurosci 22(16):7080-7. 2002
|
| 27 | DCC, NTN1
|
| Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation.
|
| Stein E, Zou Y, Poo M, Tessier-Lavigne M.
|
| Science 291(5510):1976-82. 2001
|
| 28 | DCC, NTN1, UNC5C
|
| Netrin-1 acts as a survival factor via its receptors UNC5H and DCC.
|
| Llambi F, Causeret F, Bloch-Gallego E, Mehlen P.
|
| EMBO J 20(11):2715-2722. 2001
|
| 29 | DCC, NTN1, ROBO1
|
| Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex.
|
| Stein E, Tessier-Lavigne M.
|
| Science 291(5510):1928-38. 2001
|
| 30 | NTN1
|
| Calcium signalling in the guidance of nerve growth by netrin-1.
|
| Hong K, Nishiyama M, Henley J, Tessier-Lavigne M, Poo M.
|
| Nature 403(6765):93-8 2000
|
| 31 | NTN1
|
| Netrin-1: interaction with deleted in colorectal cancer (DCC) and alterations in brain tumors and neuroblastomas.
|
| Meyerhardt JA, et al.
|
| Cell Growth Differ 10(1):35-42. 1999
|
| 32 | DCC, NTN1, UNC5C
|
| Attraction versus repulsion: modular receptors make the difference in axon guidance.
|
| Seeger MA, Beattie CE.
|
| Cell 97(7):821-4. Review. No abstract available 1999
|