Citations for
1EED, NSMAF, SMPD2, SMPD3, TNFRSF1A
The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase.
Philipp S, Puchert M, Adam-Klages S, Tchikov V, Winoto-Morbach S, Mathieu S, Deerberg A, Kolker L, Marchesini N, Kabelitz D, Hannun YA, Schütze S, Adam D.
Proc Natl Acad Sci U S A 107(3):1112-7. Epub 2009 Dec 28.PMID: 20080539 2010
2NSMAF
FAN stimulates TNF(alpha)-induced gene expression, leukocyte recruitment, and humoral response.
Montfort A, de Badts B, Douin-Echinard V, Martin PG, Iacovoni J, Nevoit C, Therville N, Garcia V, Bertrand MA, Bessières MH, Trombe MC, Levade T, Benoist H, Ségui B.
J Immunol 183(8):5369-78. Epub 2009 Sep 28.PMID: 19786552 2009
3NSMAF
The type 1 TNF receptor and its associated adapter protein, FAN, are required for TNFalpha-induced sickness behavior.
Palin K, Bluthé RM, McCusker RH, Levade T, Moos F, Dantzer R, Kelley KW.
Psychopharmacology (Berl) 201(4):549-56. Epub 2008 Sep 30.PMID: 18825372 2009
4NSMAF, SMPD3
Regulation of neutral sphingomyelinase-2 (nSMase2) by tumor necrosis factor-alpha involves protein kinase C-delta in lung epithelial cells.
Clarke CJ, Guthrie JM, Hannun YA.
Mol Pharmacol 74(4):1022-32. Epub 2008 Jul 24.PMID: 18653803 2008
5NSMAF
The WD repeat protein FAN regulates lysosome size independent from abnormal downregulation/membrane recruitment of protein kinase C.
Möhlig H, Mathieu S, Thon L, Frederiksen MC, Ward DM, Kaplan J, Schütze S, Kabelitz D, Adam D.
Exp Cell Res 313(12):2703-18. Epub 2007 Apr 24.PMID: 17512928 2007
6NSMAF
Functional characterization of the postulated intramolecular sphingolipid activator protein domain of human acid sphingomyelinase.
Kolzer M, Ferlinz K, Bartelsen O, Hoops SL, Lang F, Sandhoff K.
Biol Chem 385(12):1193-5. 2004
7NSMAF
Characterization and subcellular localization of murine and human magnesium-dependent neutral sphingomyelinase.
Tomiuk S, Zumbansen M, Stoffel W.
J Biol Chem 275(8):5710-7. 2000
8NSMAF
Assignment(1) of the human FAN protein gene (NSMAF) to human chromosome region 8q12-->q13 by in situ hybridization.
Zhang Y, Kreder D, Schwandner R, Krut O, Scherer G, Adam-Klages S, Siebert R, Kronke M, Schlegelberger B.
Cytogenet Cell Genet 87(1-2):115-116. No abstract available 1999
9NSMAF, SMPD1, TNFRSF1A
Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor.
Adam-Klages S, Schwandner R, Adam D, Kreder D, Bernardo K, Kronke M.
J Leukoc Biol 63(6):678-82. Review 1998
10NSMAF, TNFRSF1A
FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase.
Adam-Klages S, Adam D, Wiegmann K, Struve S, Kolanus W, Schneider-Mergener J, Kronke M.
Cell 86(6):937-47. 1996