1 | EED, NSMAF, SMPD2, SMPD3, TNFRSF1A
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| The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase.
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| Philipp S, Puchert M, Adam-Klages S, Tchikov V, Winoto-Morbach S, Mathieu S, Deerberg A, Kolker L, Marchesini N, Kabelitz D, Hannun YA, Schütze S, Adam D.
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| Proc Natl Acad Sci U S A 107(3):1112-7. Epub 2009 Dec 28.PMID: 20080539 2010
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2 | NSMAF
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| FAN stimulates TNF(alpha)-induced gene expression, leukocyte recruitment, and humoral response.
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| Montfort A, de Badts B, Douin-Echinard V, Martin PG, Iacovoni J, Nevoit C, Therville N, Garcia V, Bertrand MA, Bessières MH, Trombe MC, Levade T, Benoist H, Ségui B.
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| J Immunol 183(8):5369-78. Epub 2009 Sep 28.PMID: 19786552 2009
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3 | NSMAF
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| The type 1 TNF receptor and its associated adapter protein, FAN, are required for TNFalpha-induced sickness behavior.
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| Palin K, Bluthé RM, McCusker RH, Levade T, Moos F, Dantzer R, Kelley KW.
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| Psychopharmacology (Berl) 201(4):549-56. Epub 2008 Sep 30.PMID: 18825372 2009
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4 | NSMAF, SMPD3
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| Regulation of neutral sphingomyelinase-2 (nSMase2) by tumor necrosis factor-alpha involves protein kinase C-delta in lung epithelial cells.
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| Clarke CJ, Guthrie JM, Hannun YA.
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| Mol Pharmacol 74(4):1022-32. Epub 2008 Jul 24.PMID: 18653803 2008
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5 | NSMAF
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| The WD repeat protein FAN regulates lysosome size independent from abnormal downregulation/membrane recruitment of protein kinase C.
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| Möhlig H, Mathieu S, Thon L, Frederiksen MC, Ward DM, Kaplan J, Schütze S, Kabelitz D, Adam D.
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| Exp Cell Res 313(12):2703-18. Epub 2007 Apr 24.PMID: 17512928 2007
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6 | NSMAF
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| Functional characterization of the postulated intramolecular sphingolipid activator protein domain of human acid sphingomyelinase.
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| Kolzer M, Ferlinz K, Bartelsen O, Hoops SL, Lang F, Sandhoff K.
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| Biol Chem 385(12):1193-5. 2004
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7 | NSMAF
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| Characterization and subcellular localization of murine and human magnesium-dependent neutral sphingomyelinase.
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| Tomiuk S, Zumbansen M, Stoffel W.
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| J Biol Chem 275(8):5710-7. 2000
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8 | NSMAF
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| Assignment(1) of the human FAN protein gene (NSMAF) to human chromosome region 8q12-->q13 by in situ hybridization.
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| Zhang Y, Kreder D, Schwandner R, Krut O, Scherer G, Adam-Klages S, Siebert R, Kronke M, Schlegelberger B.
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| Cytogenet Cell Genet 87(1-2):115-116. No abstract available 1999
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9 | NSMAF, SMPD1, TNFRSF1A
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| Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor.
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| Adam-Klages S, Schwandner R, Adam D, Kreder D, Bernardo K, Kronke M.
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| J Leukoc Biol 63(6):678-82. Review 1998
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10 | NSMAF, TNFRSF1A
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| FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase.
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| Adam-Klages S, Adam D, Wiegmann K, Struve S, Kolanus W, Schneider-Mergener J, Kronke M.
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| Cell 86(6):937-47. 1996
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