1 | LDHB, NRF1, PPARGC1A, TIGAR
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| TIGAR promotes neural stem cell differentiation through acetyl-CoA-mediated histone acetylation.
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| Zhou W, Zhao T, Du J, Ji G, Li X, Ji S, Tian W, Wang X, Hao A.
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| Cell Death Dis 10(3):198. doi: 10.1038/s41419-019-1434-3. 2019
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2 | NGLY1, NRF1
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| N-glycanase NGLY1 regulates mitochondrial homeostasis and inflammation through NRF1.
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| Yang K, Huang R, Fujihira H, Suzuki T, Yan N.
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| J Exp Med 215(10):2600-2616. doi: 10.1084/jem.20180783. Epub 2018 Aug 22.
2018
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3 | ASZ1, NRF1
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| NRF1 coordinates with DNA methylation to regulate spermatogenesis.
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| Wang J, Tang C, Wang Q, Su J, Ni T, Yang W, Wang Y, Chen W, Liu X, Wang S, Zhang J, Song H, Zhu J, Wang Y.
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| FASEB J ASEB J. 2017 Jul 28. pii: fj.201700093R. doi: 10.1096/fj.201700093R. [Epub ahead of print]
2017
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4 | CXCR4, NRF1
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| Nuclear Respiratory Factor-1 (NRF-1) Regulates Transcription of the CXC Receptor 4 (CXCR4) in the Rat Retina.
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| Chen P, Cai X, Yang Y, Chen Z, Qiu J, Yu N, Tang M, Wang Q, Ge J, Yu K, Zhuang J.
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| Invest Ophthalmol Vis Sci 58(11):4662-4669. doi: 10.1167/iovs.17-22115.
2017
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5 | NRF1
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| Elucidation of the therapeutic role of mitochondrial biogenesis transducers NRF-1 in the regulation of renal fibrosis.
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| Hsieh PF, Liu SF, Hung TJ, Hung CY, Liu GZ, Chuang LY, Chen MF, Wang JL, Shi MD, Hsu CH, Shiue YL, Yang YL.
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| Exp Cell Res 349(1):23-31. doi: 10.1016/j.yexcr.2016.09.005. Epub 2016 Sep 12.
2016
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6 | COX6C, NRF1
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| Nuclear Respiratory Factor-1 (NRF-1) Gene Expression in Chronic Kidney Disease Patients Undergoing Hemodialysis and Mitochondrial Oxidative Dysregulation.
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| Hashad D, Elgohry I, Dwedar F.
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| Clin Lab 62(11):2149-2154. doi: 10.7754/Clin.Lab.2016.160329.
2016
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7 | HERPUD1, NRF1
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| Induction of Herpud1 expression by ER stress is regulated by Nrf1.
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| Ho DV, Chan JY.
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| FEBS Lett 589(5):615-20. doi: 10.1016/j.febslet.2015.01.026. Epub 2015 Jan 28.
2015
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8 | NRF1
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| Competition between DNA methylation and transcription factors determines binding of NRF1.
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| Domcke S, Bardet AF, Adrian Ginno P, Hartl D, Burger L, Schübeler D.
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| Nature 528(7583):575-9. doi: 10.1038/nature16462. Epub 2015 Dec 16.
2015
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9 | BRK1, ENOX1, NRF1, RETREG3
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| Novel genes FAM134C, C3orf10 and ENOX1 are regulated by NRF-1 and differentially regulate neurite outgrowth in neuroblastoma cells and hippocampal neurons.
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| Wang JL, Tong CW, Chang WT, Huang AM.
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| Gene 529(1):7-15. doi: 10.1016/j.gene.2013.08.006. Epub 2013 Aug 9.
2013
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10 | NRF1
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| The membrane-topogenic vectorial behaviour of Nrf1 controls its post-translational modification and transactivation activity.
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| Zhang Y, Hayes JD.
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| Sci Rep 3:2006. doi: 10.1038/srep02006.
2013
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11 | NFE2L2, NRF1, PPARGC1A, TFAM
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| Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease.
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| Sheng B, Wang X, Su B, Lee HG, Casadesus G, Perry G, Zhu X.
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| J Neurochem. 120(3):419-29 2012
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12 | NRF1
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| Regulation of Na(+)/K(+)-ATPase by nuclear respiratory factor 1: implication in the tight coupling of neuronal activity, energy generation, and energy consumption.
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| Johar K, Priya A, Wong-Riley MT.
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| J Biol Chem 287(48):40381-90. doi: 10.1074/jbc.M112.414573. Epub 2012 Oct 9.
2012
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13 | BTRC, NRF1, SYVN1
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| Dual regulation of the transcriptional activity of Nrf1 by β-TrCP- and Hrd1-dependent degradation mechanisms.
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| Tsuchiya Y, Morita T, Kim M, Iemura S, Natsume T, Yamamoto M, Kobayashi A.
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| Mol Cell Biol 31(22):4500-12. doi: 10.1128/MCB.05663-11. Epub 2011 Sep 12. 2011
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14 | GRIN1, GRIN2B, KIF17, NRF1
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| The kinesin superfamily protein KIF17 is regulated by the same transcription factor (NRF-1) as its cargo NR2B in neurons.
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| Dhar SS, Wong-Riley MT.
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| Biochim Biophys Acta 1813(3):403-11. doi: 10.1016/j.bbamcr.2010.12.013. Epub 2010 Dec 21.
2011
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15 | CFM, NRF1, SLC46A1
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| The obligatory intestinal folate transporter PCFT (SLC46A1) is regulated by nuclear respiratory factor 1.
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| Gonen N, Assaraf YG.
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| J Biol Chem 285(44):33602-13. Epub 2010 Aug 19. 2010
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16 | ACACB, NFE2L1, NRF1
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| AMPK activation represses the human gene promoter of the cardiac isoform of acetyl-CoA carboxylase: Role of nuclear respiratory factor-1.
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| Adam T, Opie LH, Essop MF.
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| Biochem Biophys Res Commun 398(3):495-9. Epub 2010 Jul 1. 2010
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17 | ESRRA, NRF1, PPARGC1B
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| PGC-1 beta-regulated mitochondrial biogenesis and function in myotubes is mediated by NRF-1 and ERR alpha.
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| Shao D, Liu Y, Liu X, Zhu L, Cui Y, Cui A, Qiao A, Kong X, Liu Y, Chen Q, Gupta N, Fang F, Chang Y.
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| Mitochondrion 10(5):516-27. Epub 2010 May 31.
2010
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18 | NRF1
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| Poly(ADP-ribose) Polymerase 1 Interacts with Nuclear Respiratory Factor 1 (NRF-1) and Plays a Role in NRF-1 Transcriptional Regulation.
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| Hossain MB, Ji P, Anish R, Jacobson RH, Takada S.
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| J Biol Chem. 284(13):8621-32. 2009
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19 | HPCA, HPCAL1, HPCAL4, NCALD, NRF1, VSNL1
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| Promoter regulation of the visinin-like subfamily of neuronal calcium sensor proteins by nuclear respiratory factor-1.
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| Fu J, Zhang J, Jin F, Patchefsky J, Braunewell KH, Klein-Szanto AJ.
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| J Biol Chem 284(40):27577-86. doi: 10.1074/jbc.M109.049361. Epub 2009 Aug 12.
2009
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20 | CAPNS1, NRF1
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| NRF-1, and AP-1 regulate the promoter of the human calpain small subunit 1 (CAPNS1) gene.
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| Asangani IA, Rasheed SA, Leupold JH, Post S, Allgayer H.
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| Gene 410(1):197-206. Epub 2007 Dec 23. 2008
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21 | MEF2A, NRF1
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| Nuclear respiratory factor 1 controls myocyte enhancer factor 2A transcription to provide a mechanism for coordinate expression of respiratory chain subunits.
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| Ramachandran B, Yu G, Gulick T.
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| J Biol Chem 283(18):11935-46. Epub 2008 Jan 24.
2008
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22 | NRF1
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| Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain. Inhibition of nuclear translocation and transacting function.
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| Wang W, Chan JY.
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| J Biol Chem 281(28):19676-87. Epub 2006 May 10. 2006
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23 | NRF1
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| A novel function of transcription factor alpha-Pal/NRF-1: increasing neurite outgrowth.
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| Chang WT, Chen HI, Chiou RJ, Chen CY, Huang AM.
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| Biochem Biophys Res Commun 334(1):199-206. 2005
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24 | FMR1, NRF1
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| The roles of Sp1, Sp3, USF1/USF2 and NRF-1 in the regulation and three-dimensional structure of the Fragile X mental retardation gene promoter.
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| Kumari D, Gabrielian A, Wheeler D, Usdin K.
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| Biochem J 386(Pt 2):297-303. 2005
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25 | NRF1
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| Association between polymorphisms in the nuclear respiratory factor 1 gene and type 2 diabetes mellitus in the Korean population.
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| Cho YM, Shin HD, Park BL, Kim JH, Park KS, Kim SY, Lee HK.
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| Diabetologia 48(10):2033-8. Epub 2005 Aug 5. 2005
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26 | NRF1, CD47
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| Alpha-Pal/NRF-1 regulates the promoter of the human integrin-associated protein/CD47 gene.
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| Chang WT, Huang AM.
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| J Biol Chem 279(15):14542-50. Epub 2004 Jan 27. 2004
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27 | NRF1
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| A common set of gene regulatory networks links metabolism and growth inhibition.
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| Cam H, Balciunaite E, Blais A, Spektor A, Scarpulla RC, Young R, Kluger Y, Dynlacht BD.
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| Mol Cell. 16(3):399-411. 2004
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28 | NRF1
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| The CCAAT enhancer-binding protein (C/EBP)beta and Nrf1 interact to regulate dentin sialophosphoprotein (DSPP) gene expression during odontoblast differentiation.
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| Narayanan K, Ramachandran A, Peterson MC, Hao J, Kolstø AB, Friedman AD, George A.
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| J Biol Chem. 279(44):45423-32. 2004
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29 | NRF1, NRF2
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| Cloning MafF by recognition site screening with the NFE2 tandem repeat of HS2: analysis of its role in globin and GCSl genes regulation.
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| Marini MG, Asunis I, Chan K, Chan JY, Kan YW, Porcu L, Cao A, Moi P.
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| Blood Cells Mol Dis. 29(2):145-58. 2002
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30 | NRF1
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| Dynein light chain interacts with NRF-1 and EWG, structurally and functionally related transcription factors from humans and drosophil
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| Herzig RP, Andersson U, Scarpulla RC.
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| J Cell Sci. 113 Pt 23:4263-73. 2000
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31 | NRF1, PPARGC1A
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| Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1.
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| Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, Troy A, Cinti S, Lowell B, Scarpulla RC, Spiegelman BM.
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| Cell. 98(1):115-24. 1999
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32 | GABPA, GABPAP, GABPB1, NRF1
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| Nuclear respiratory factors 1 and 2 utilize similar glutamine-containing clusters of hydrophobic residues to activate transcription.
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| Gugneja S, Virbasius CM, Scarpulla RC.
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| Mol Cell Biol 16(10):5708-16. 1996
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33 | NRF1
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| The gene (NFE2L1) for human NRF-1, an activator involved in nuclear-mitochondrial interactions, maps to 7q32.
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| Tiranti V, et al.
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| Genomics 27 : 555-557. 1995
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34 | NRF1
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| The pre-mRNA of nuclear respiratory factor 1, a regulator of mitochondrial biogenesis, is alternatively spliced in human tissues and cell lines.
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| Spelbrink JN, et al.
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| Hum Mol Genet 4 : 1591-1596. 1995
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35 | NRF1
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| Structure, expression, and chromosomal assignment of the human gene encoding nuclear respiratory factor 1.
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| Gopalakrishnan L, et al.
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| J Biol Chem 270 : 18019-18025. 1995
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