| 1 | NKX6-1, NR4A1, NR4A3
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| Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors.
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| Tessem JS, Moss LG, Chao LC, Arlotto M, Lu D, Jensen MV, Stephens SB, Tontonoz P, Hohmeier HE, Newgard CB.
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| Proc Natl Acad Sci U S A 111(14):5242-7. doi: 10.1073/pnas.1320953111. Epub 2014 Mar 24.
2014
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| 2 | NR4A1, NR4A2, NR4A3
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| Regulation of NR4A by nutritional status, gender, postnatal development and hormonal deficiency.
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| Pérez-Sieira S, López M, Nogueiras R, Tovar S.
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| Sci Rep 4:4264. doi: 10.1038/srep04264.
2014
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| 3 | NR3C1, NR4A3
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| Control of energy balance by hypothalamic gene circuitry involving two nuclear receptors, neuron-derived orphan receptor 1 and glucocorticoid receptor.
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| Kim SG, Lee B, Kim DH, Kim J, Lee S, Lee SK, Lee JW.
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| Mol Cell Biol 33(19):3826-34. doi: 10.1128/MCB.00385-13. Epub 2013 Jul 29.
2013
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| 4 | NR4A1, NR4A2, NR4A3
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| Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis.
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| Sekiya T, Kashiwagi I, Yoshida R, Fukaya T, Morita R, Kimura A, Ichinose H, Metzger D, Chambon P, Yoshimura A.
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| Nat Immunol 14(3):230-7. doi: 10.1038/ni.2520. Epub 2013 Jan 20.
2013
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| 5 | NR4A1, NR4A2, NR4A3, PIN1
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| Dual function of Pin1 in NR4A nuclear receptor activation: enhanced activity of NR4As and increased Nur77 protein stability.
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| van Tiel CM, Kurakula K, Koenis DS, van der Wal E, de Vries CJ.
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| Biochim Biophys Acta 1823(10):1894-904. doi: 10.1016/j.bbamcr.2012.06.030. Epub 2012 Jul 10.
2012
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| 6 | NR4A3
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| NR4A3 rearrangement reliably distinguishes between the clinicopathologically overlapping entities myoepithelial carcinoma of soft tissue and cellular extraskeletal myxoid chondrosarcoma.
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| Flucke U, Tops BB, Verdijk MA, van Cleef PJ, van Zwam PH, Slootweg PJ, Bovée JV, Riedl RG, Creytens DH, Suurmeijer AJ, Mentzel T.
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| Virchows Arch 460(6):621-8. doi: 10.1007/s00428-012-1240-0. Epub 2012 May 9.
2012
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| 7 | NR4A1, NR4A2, NR4A3
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| The Nuclear Orphan Receptors NR4A as Therapeutic Target in Cancer Therapy.
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| Deutsch AJ, Angerer H, Fuchs TE, Neumeister P.
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| Anticancer Agents Med Chem 12(9):1001-14.
2012
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| 8 | NR4A3
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| Distribution and expression of alternative splice isoforms of NOR1 in human tissues and cell lines.
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| Xiang B, Wang W, Yi M, Li W, Zhou M, Li X, Li G.
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| Zhong Nan Da Xue Xue Bao Yi Xue Ban 36(7):597-603. doi: 10.3969/j.issn.1672-7347.2011.07.003.
2011
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| 9 | NR4A3
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| Down-regulation of the RUNX1-target gene NR4A3 contributes to hematopoiesis deregulation in familial platelet disorder/acute myelogenous leukemia.
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| Bluteau D, Gilles L, Hilpert M, Antony-Debré I, James C, Debili N, Camara-Clayette V, Wagner-Ballon O, Cordette-Lagarde V, Robert T, Ripoche H, Gonin P, Swierczek S, Prchal J, Vainchenker W, Favier R, Raslova H.
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| Blood 118(24):6310-20. doi: 10.1182/blood-2010-12-325555. Epub 2011 Jul 1.
2011
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| 10 | NR4A1, NR4A2, NR4A3
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| Differential regulation of Nr4a subfamily nuclear receptors following mast cell activation.
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| Lundequist A, Calounova G, Wensman H, Rönnberg E, Pejler G.
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| Mol Immunol 48(15-16):1753-61. doi: 10.1016/j.molimm.2011.04.017. Epub 2011 May 31.
2011
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| 11 | CDKN1B, NR4A3, SKP2
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| Transcriptional regulation of S phase kinase-associated protein 2 by NR4A orphan nuclear receptor NOR1 in vascular smooth muscle cells.
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| Gizard F, Zhao Y, Findeisen HM, Qing H, Cohn D, Heywood EB, Jones KL, Nomiyama T, Bruemmer D.
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| J Biol Chem 286(41):35485-93. doi: 10.1074/jbc.M111.295840. Epub 2011 Aug 25.
2011
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| 12 | CREB1, NR4A1, NR4A2, NR4A3
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| NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection.
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| Volakakis N, Kadkhodaei B, Joodmardi E, Wallis K, Panman L, Silvaggi J, Spiegelman BM, Perlmann T.
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| Proc Natl Acad Sci U S A 107(27):12317-22. Epub 2010 Jun 21. 2010
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| 13 | NR4A3
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| Deficiency of the NR4A orphan nuclear receptor NOR1 decreases monocyte adhesion and atherosclerosis.
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| Zhao Y, Howatt DA, Gizard F, Nomiyama T, Findeisen HM, Heywood EB, Jones KL, Conneely OM, Daugherty A, Bruemmer D.
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| Circ Res 107(4):501-11. doi: 10.1161/CIRCRESAHA.110.222083. Epub 2010 Jun 17.
2010
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| 14 | NR4A3
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| The hypoxia-inducible factor 1/NOR-1 axis regulates the survival response of endothelial cells to hypoxia.
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| Martorell L, Gentile M, Rius J, Rodríguez C, Crespo J, Badimon L, Martínez-González J.
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| Mol Cell Biol 29(21):5828-42. Epub 2009 Aug 31.
2009
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| 15 | NR4A3
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| The orphan nuclear receptor, NOR-1, a target of beta-adrenergic signaling, regulates gene expression that controls oxidative metabolism in skeletal muscle.
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| Pearen MA, Myers SA, Raichur S, Ryall JG, Lynch GS, Muscat GE.
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| Endocrinology 149(6):2853-65. Epub 2008 Mar 6.
2008
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| 16 | NR4A3
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| Neuron-derived orphan receptor-1 (NOR-1) is induced by thrombin and mediates vascular endothelial cell growth.
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| Martorell L, MartĂnez-González J, Crespo J, Calvayrac O, Badimon L.
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| J Thromb Haemost 5(8):1766-73. Epub 2007 May 21.
2007
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| 17 | NR4A1, NR4A2, NR4A3
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| NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism.
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| Pei L, Waki H, Vaitheesvaran B, Wilpitz DC, Kurland IJ, Tontonoz P.
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| Nat Med 12(9):1048-55. Epub 2006 Aug 13. 2006
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| 18 | NR4A3
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| The NR4A orphan nuclear receptor NOR1 is induced by platelet-derived growth factor and mediates vascular smooth muscle cell proliferation.
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| Nomiyama T, Nakamachi T, Gizard F, Heywood EB, Jones KL, Ohkura N, Kawamori R, Conneely OM, Bruemmer D.
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| J Biol Chem 281(44):33467-76. Epub 2006 Aug 31.
2006
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| 19 | TFG, NR4A3
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| TFG is a novel fusion partner of NOR1 in extraskeletal myxoid chondrosarcoma.
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| Hisaoka M, Ishida T, Imamura T, Hashimoto H.
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| Genes Chromosomes Cancer 40(4):325-8. 2004
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| 20 | TLX1, NR4A3
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| A microarray model system identifies potential new target genes of the proto-oncogene HOX11.
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| Hoffmann K, Dixon DN, Greene WK, Ford J, Taplin R, Kees UR.
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| Genes Chromosomes Cancer 41(4):309-20. 2004
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| 21 | HPE2, SIX3, NR4A3
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| Functional characterization of SIX3 homeodomain mutations in holoprosencephaly: interaction with the nuclear receptor NR4A3/NOR1.
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| Laflamme C, Filion C, Labelle Y.
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| Hum Mutat 24(6):502-8. 2004
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| 22 | NR4A3, SIX3
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| Coexpression of NOR1 and SIX3 proteins in extraskeletal myxoid chondrosarcomas without detectable NR4A3 fusion genes.
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| Hisaoka M, Okamoto S, Yokoyama K, Hashimoto H.
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| Cancer Genet Cytogenet 152(2):101-7. 2004
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| 23 | NR4A3
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| Neuron-derived orphan receptor-1 (NOR-1) modulates vascular smooth muscle cell proliferation.
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| Martinez-Gonzalez J, Rius J, Castello A, Cases-Langhoff C, Badimon L.
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| Circ Res 92(1):96-103. 2003
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| 24 | COL1A1, DDIT3, EWSR1, SUZ12, JAZF1, NR4A3, WT1
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| Cytogenetics and molecular genetics of bone and soft-tissue tumors.
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| Sandberg AA.
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| Am J Med Genet 115(3):189-93. 2002
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| 25 | EWSR1, NR4A3, TAF15
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| Molecular genetic characterization of the EWS/CHN and RBP56/CHN fusion genes in extraskeletal myxoid chondrosarcoma.
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| Panagopoulos I, Mertens F, Isaksson M, Domanski HA, Brosjo O, Heim S, Bjerkehagen B, Sciot R, Dal Cin P, Fletcher JA, Fletcher CD, Mandahl N.
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| Genes Chromosomes Cancer 35(4):340-52. 2002
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| 26 | EWSR1, NR4A3
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| The EWS/NOR1 fusion gene product gains a novel activity affecting pre-mRNA splicing.
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| Ohkura N, Yaguchi H, Tsukada T, Yamaguchi K.
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| J Biol Chem 277(1):535-43. Epub 2001 Oct 22. 2002
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| 27 | NR4A3, EWSR1
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| Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.
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| Unger T, et al.
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| Oncogene 18(21):3205-12. 1999
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| 28 | NR4A3, TAF15
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| Identification of a novel fusion gene involving hTAFII68 and CHN from a t(9;17)(q22;q11.2) translocation in an extraskeletal myxoid chondrosarcoma.
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| Attwooll C, Tariq M, Harris M, Coyne JD, Telford N, Varley JM.
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| Oncogene 18(52):7599-601. 1999
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| 29 | NR4A3, TAF15
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| Fusion of the RBP56 and CHN genes in extraskeletal myxoid chondrosarcomas with translocation t(9;17)(q22;q11).
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| Panagopoulos I, Mencinger M, Dietrich CU, Bjerkehagen B, Saeter G, Mertens F, Mandahl N, Heim S.
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| Oncogene 18(52):7594-8. 1999
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| 30 | NR4A3
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| Alternative splicing generates isoforms of human neuron-derived orphan receptor-1 (NOR-1) mRNA.
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| Ohkura N, et al.
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| Gene 211 : 79-85. 1998
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| 31 | NR4A3, HSAN1, MSSE, NINJ1
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| A YAC-based transcript map of human chromosome 9p22.1-q22.3 encompassing the loci for hereditary sensory neuropathy type I and multiple self-healing squamous epithelioma.
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| Blair IP, et al.
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| Genomics 51 : 277-281. 1998
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| 32 | EWSR1, NR4A3, MCHS
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| Fusion of the EWS gene to CHN, a member of the steroid/thyroid receptor gene superfamily, in a human myxoid chondrosarcoma.
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| Clark J, et al.
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| Oncogene 12 : 229-235. 1996
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| 33 | NR4A3
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| Localization of TEC to 9q22.3-q31 by fluorescence in situ hybridization.
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| Kleinfinger P, et al.
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| Ann Genet 39 : 233-235. 1996
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| 34 | NR4A3
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| Structure, mapping and expression of a human NOR-1 gene, the third member of the Nur77/NGFI-B family.
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| Ohkura N, et al.
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| Biochim Biophys Acta 1308 : 205-214. 1996
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| 35 | NR4A3
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| Oncogenic conversion of a novel orphan nuclear receptor by chromosome translocation.
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| Labelle Y, et al.
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| Hum Mol Genet 4 : 2219-2226. 1995
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| 36 | NR4A3, EWSR1, MCHS
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| Fusion of the EWS gene to a DNA segment from 9q22-31 in a human myxoid chondrosarcoma.
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| Gill S, et al.
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| Genes Chromosomes Cancer 12 : 307-310. 1995
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| 37 | NR4A3
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| Molecular cloning of a novel steroid/thyroid receptor superfamily gene from cultured rat neuronal cells.
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| Ohkura N, et al.
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| Biochem Biophys Res Commun 205 : 1959-1965. 1994
|