1 | NR2F1, OAID
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| NR2F1 Mutations Cause Optic Atrophy with Intellectual Disability.
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| Bosch DG, Boonstra FN, Gonzaga-Jauregui C, Xu M, de Ligt J, Jhangiani S, Wiszniewski W, Muzny DM, Yntema HG, Pfundt R, Vissers LE, Spruijt L, Blokland EA, Chen CA; Baylor-Hopkins Center for Mendelian Genomics, Lewis RA, Tsai SY, Gibbs RA, Tsai MJ, Lupski JR, Zoghbi HY, Cremers FP, de Vries BB, Schaaf CP.
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| Am J Hum Genet 94(2):303-9. doi: 10.1016/j.ajhg.2014.01.002. Epub 2014 Jan 23.
2014
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2 | NR2F1, OAID
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| NR2F1 Mutations Cause Optic Atrophy with Intellectual Disability.
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| Bosch DG, Boonstra FN, Gonzaga-Jauregui C, Xu M, de Ligt J, Jhangiani S, Wiszniewski W, Muzny DM, Yntema HG, Pfundt R, Vissers LE, Spruijt L, Blokland EA, Chen CA; Baylor-Hopkins Center for Mendelian Genomics, Lewis RA, Tsai SY, Gibbs RA, Tsai MJ, Lupski JR, Zoghbi HY, Cremers FP, de Vries BB, Schaaf CP.
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| Am J Hum Genet 94(2):303-9. doi: 10.1016/j.ajhg.2014.01.002. Epub 2014 Jan 23.
2014
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3 | NR2F1, OAID
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| NR2F1 haploinsufficiency is associated with optic atrophy, dysmorphism and global developmental delay.
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| Al-Kateb H, Shimony JS, Vineyard M, Manwaring L, Kulkarni S, Shinawi M.
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| Am J Med Genet A 161A(2):377-81. doi: 10.1002/ajmg.a.35650. Epub 2013 Jan 8. No abstract available.
2013
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4 | HOXA5, NR2F1
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| Polycomb recruitment attenuates retinoic acid-induced transcription of the bivalent NR2F1 gene.
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| Laursen KB, Mongan NP, Zhuang Y, Ng MM, Benoit YD, Gudas LJ.
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| Nucleic Acids Res 41(13):6430-43. doi: 10.1093/nar/gkt367. Epub 2013 May 10.
2013
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5 | NR2F1
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| COUP-TFI controls activity-dependent tyrosine hydroxylase expression in adult dopaminergic olfactory bulb interneurons.
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| Bovetti S, Bonzano S, Garzotto D, Giannelli SG, Iannielli A, Armentano M, Studer M, De Marchis S.
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| Development 140(24):4850-9. doi: 10.1242/dev.089961. Epub 2013 Nov 13.
2013
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6 | NR2F1
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| CoupTFI interacts with retinoic acid signaling during cortical development.
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| Harrison-Uy SJ, Siegenthaler JA, Faedo A, Rubenstein JL, Pleasure SJ.
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| PLoS One 8(3):e58219. doi: 10.1371/journal.pone.0058219. Epub 2013 Mar 5. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/f9bd989 2013
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7 | CYP26A1, HOXA1, NR2F1
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| Role of COUP-TFI during retinoic acid-induced differentiation of P19 cells to endodermal cells.
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| Pickens BS, Teets BW, Soprano KJ, Soprano DR.
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| J Cell Physiol 228(4):791-800. doi: 10.1002/jcp.24228.
2013
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8 | MTTP, NR2F1
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| NR2F1 disrupts synergistic activation of the MTTP gene transcription by HNF-4α and HNF-1α.
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| Dai K, Hussain MM.
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| J Lipid Res 53(5):901-8. doi: 10.1194/jlr.M025130. Epub 2012 Feb 22.
2012
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9 | NR2F1, RND2
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| COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression.
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| Alfano C, Viola L, Heng JI, Pirozzi M, Clarkson M, Flore G, De Maio A, Schedl A, Guillemot F, Studer M.
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| Development. 138(21):4685-97. 2011
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10 | NR2F1
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| Thyroid hormone and COUP-TF1 regulate kallikrein-binding protein (KBP) gene expression.
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| Liu YY, Nakatani T, Kogai T, Mody K, Brent GA.
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| Endocrinology 152(3):1143-53. doi: 10.1210/en.2010-0580. Epub 2011 Jan 25.
2011
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11 | CYP3A4, NR1I2, NR2F1, NR2F2, THRA, THRB
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| Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element binding.
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| Istrate MA, Nussler AK, Eichelbaum M, Burk O.
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| Biochem Biophys Res Commun 393(4):688-93. Epub 2010 Feb 18.PMID: 20171174 2010
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12 | NR2F1, NR2F2
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| COUP-TFs regulate eye development by controlling factors essential for optic vesicle morphogenesis.
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| Tang K, Xie X, Park JI, Jamrich M, Tsai S, Tsai MJ.
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| Development 137(5):725-34.PMID: 20147377 2010
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13 | NR2F1
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| Area-specific temporal control of corticospinal motor neuron differentiation by COUP-TFI.
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| Tomassy GS, De Leonibus E, Jabaudon D, Lodato S, Alfano C, Mele A, Macklis JD, Studer M.
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| Proc Natl Acad Sci U S A 107(8):3576-81. Epub 2010 Feb 2.PMID: 20133588 2010
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14 | NR2F1, NR2F2
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| COUP-TFI and -TFII nuclear receptors are expressed in amacrine cells and play roles in regulating the differentiation of retinal progenitor cells.
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| Inoue M, Iida A, Satoh S, Kodama T, Watanabe S.
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| Exp Eye Res 90(1):49-56. Epub 2009 Sep 17.PMID: 19766631 2010
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15 | ERN2, MTTP, NR2F1
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| NR2F1 and IRE1beta suppress microsomal triglyceride transfer protein expression and lipoprotein assembly in undifferentiated intestinal epithelial cells.
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| Dai K, Khatun I, Hussain MM.
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| Arterioscler Thromb Vasc Biol 30(3):568-74. doi: 10.1161/ATVBAHA.109.198135. Epub 2009 Dec 10.
2010
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16 | NR2F1, TNFAIP8
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| A chicken ovalbumin upstream promoter transcription factor I (COUP-TFI) complex represses expression of the gene encoding tumor necrosis factor alpha-induced protein 8 (TNFAIP8).
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| Zhang LJ, Liu X, Gafken PR, Kioussi C, Leid M.
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| J Biol Chem 284(10):6156-68. Epub 2008 Dec 26.
2009
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17 | NR2F1
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| COUP-TFI modulates estrogen signaling and influences proliferation, survival and migration of breast cancer cells.
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| Le Dily F, Métivier R, Guéguen MM, Le Péron C, Flouriot G, Tas P, Pakdel F.
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| Breast Cancer Res Treat 110(1):69-83. Epub 2007 Aug 3.
2008
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18 | NR2F1
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| COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling.
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| Faedo A, Tomassy GS, Ruan Y, Teichmann H, Krauss S, Pleasure SJ, Tsai SY, Tsai MJ, Studer M, Rubenstein JL.
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| Cereb Cortex 18(9):2117-31. Epub 2007 Dec 28.PMID: 18165280 2008
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19 | NR2F1
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| Genotype-dependent activation or repression of HBV enhancer II by transcription factor COUP-TF1.
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| Fischer SF, Schmidt K, Fiedler N, Glebe D, Schüttler C, Sun J, Gerlich WH, Repp R, Schaefer S.
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| World J Gastroenterol 12(37):6054-8.
2006
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20 | NR2F1
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| COUP-TFI is required for the formation of commissural projections in the forebrain by regulating axonal growth.
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| Armentano M, Filosa A, Andolfi G, Studer M.
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| Development 133(21):4151-62. Epub 2006 Oct 4.PMID: 17021036 2006
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21 | CYP11A1, CYP11B1, CYP11B2, CYP17A1D, CYP19A1, GATA4, NR0B1, NR2F1, NR2F2, NR5A1, PCNA, COPS2
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| DAX1 and its network partners: exploring complexity in development.
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| Clipsham R, McCabe ER.
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| Mol Genet Metab 80(1-2):81-120. 2003
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22 | MAPK1, NR2F1
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| Formation of an hER alpha-COUP-TFI complex enhances hER alpha AF-1 through Ser118 phosphorylation by MAPK.
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| Métivier R, Gay FA, Hübner MR, Flouriot G, Salbert G, Gannon F, Kah O, Pakdel F.
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| EMBO J. 21(13):3443-53. 2002
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23 | CALR, NKX2-5, NR2F1
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| COUP-TF1 antagonizes Nkx2.5-mediated activation of the calreticulin gene during cardiac development.
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| Guo L, Lynch J, Nakamura K, Fliegel L, Kasahara H, Izumo S, Komuro I, Agellon LB, Michalak M.
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| J Biol Chem 276(4):2797-801. 2001
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24 | NR2F1, NR2F6
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| Nuclear orphan receptors regulate transcription of the gene for the human luteinizing hormone receptor.
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| Zhang Y, Dufau ML.
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| J Biol Chem 275(4):2763-70. 2000
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25 | NR2F1
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| The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERRalpha1.
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| Klinge CM, Kaur K, Swanson HI.
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| Arch Biochem Biophys. 373(1):163-74. 2000
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26 | NR2F1
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| Transcription activation by the orphan nuclear receptor, chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI). Definition of the domain involved in the glucocorticoid response of the phosphoenolpyruvate carboxykinase gene
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| Sugiyama T, Wang JC, Scott DK, Granner DK.
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| J Biol Chem. 275(5):3446-54. 2000
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27 | NR2F1, NR2F6, NR4A2
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| Identification of nuclear orphan receptors as regulators of expression of a neurotransmitter receptor gene.
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| Chew LJ, Huang F, Boutin JM, Gallo V.
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| J Biol Chem 274(41):29366-75. 1999
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28 | COPS2, NR2F1
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| Alien, a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily.
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| Dressel U, Thormeyer D, Altincicek B, Paululat A, Eggert M, Schneider S, Tenbaum SP, Renkawitz R, Baniahmad A.
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| Mol Cell Biol 19(5):3383-94. 1999
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29 | NR2F1
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| COUP-TF and Sp1 interact and cooperate in the transcriptional activation of the human immunodeficiency virus type 1 long terminal repeat in human microglial cells.
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| Rohr O, Aunis D, Schaeffer E.
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| J Biol Chem. 272(49):31149-55. 1997
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30 | NR2F1
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| Chicken ovalbumin upstream promoter-transcription factor interacts with estrogen receptor, binds to estrogen response elements and half-sites, and inhibits estrogen-induced gene expression.
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| Klinge CM, Silver BF, Driscoll MD, Sathya G, Bambara RA, Hilf R.
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| J Biol Chem. 272(50):31465-74. 1997
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31 | NR2F1, NR2F2
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| Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes.
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| Qiu Y, et al.
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| Genomics 29 : 240-246. 1995
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32 | NR2F1
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| Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II).
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| Ing NH, Beekman JM, Tsai SY, Tsai MJ, O'Malley BW.
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| J Biol Chem. 267(25):17617-23. 1992
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33 | NR2F1
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| Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling.
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| Kliewer SA, Umesono K, Heyman RA, Mangelsdorf DJ, Dyck JA, Evans RM.
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| Proc Natl Acad Sci U S A. 89(4):1448-52. 1992
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34 | NR2F1
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| Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein.
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| Berrodin TJ, Marks MS, Ozato K, Linney E, Lazar MA.
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| Mol Endocrinol. 6(9):1468-78. 1992
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35 | NR2F1, NR2F6
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| Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related to each other.
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| Miyajima N, et al.
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| Nucleic Acids Res 16 : 11057-11074. 1988
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