Citations for
1NR2F1, OAID
NR2F1 Mutations Cause Optic Atrophy with Intellectual Disability.
Bosch DG, Boonstra FN, Gonzaga-Jauregui C, Xu M, de Ligt J, Jhangiani S, Wiszniewski W, Muzny DM, Yntema HG, Pfundt R, Vissers LE, Spruijt L, Blokland EA, Chen CA; Baylor-Hopkins Center for Mendelian Genomics, Lewis RA, Tsai SY, Gibbs RA, Tsai MJ, Lupski JR, Zoghbi HY, Cremers FP, de Vries BB, Schaaf CP.
Am J Hum Genet 94(2):303-9. doi: 10.1016/j.ajhg.2014.01.002. Epub 2014 Jan 23. 2014
2NR2F1, OAID
NR2F1 Mutations Cause Optic Atrophy with Intellectual Disability.
Bosch DG, Boonstra FN, Gonzaga-Jauregui C, Xu M, de Ligt J, Jhangiani S, Wiszniewski W, Muzny DM, Yntema HG, Pfundt R, Vissers LE, Spruijt L, Blokland EA, Chen CA; Baylor-Hopkins Center for Mendelian Genomics, Lewis RA, Tsai SY, Gibbs RA, Tsai MJ, Lupski JR, Zoghbi HY, Cremers FP, de Vries BB, Schaaf CP.
Am J Hum Genet 94(2):303-9. doi: 10.1016/j.ajhg.2014.01.002. Epub 2014 Jan 23. 2014
3NR2F1, OAID
NR2F1 haploinsufficiency is associated with optic atrophy, dysmorphism and global developmental delay.
Al-Kateb H, Shimony JS, Vineyard M, Manwaring L, Kulkarni S, Shinawi M.
Am J Med Genet A 161A(2):377-81. doi: 10.1002/ajmg.a.35650. Epub 2013 Jan 8. No abstract available. 2013
4HOXA5, NR2F1
Polycomb recruitment attenuates retinoic acid-induced transcription of the bivalent NR2F1 gene.
Laursen KB, Mongan NP, Zhuang Y, Ng MM, Benoit YD, Gudas LJ.
Nucleic Acids Res 41(13):6430-43. doi: 10.1093/nar/gkt367. Epub 2013 May 10. 2013
5NR2F1
COUP-TFI controls activity-dependent tyrosine hydroxylase expression in adult dopaminergic olfactory bulb interneurons.
Bovetti S, Bonzano S, Garzotto D, Giannelli SG, Iannielli A, Armentano M, Studer M, De Marchis S.
Development 140(24):4850-9. doi: 10.1242/dev.089961. Epub 2013 Nov 13. 2013
6NR2F1
CoupTFI interacts with retinoic acid signaling during cortical development.
Harrison-Uy SJ, Siegenthaler JA, Faedo A, Rubenstein JL, Pleasure SJ.
PLoS One 8(3):e58219. doi: 10.1371/journal.pone.0058219. Epub 2013 Mar 5. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/f9bd989 2013
7CYP26A1, HOXA1, NR2F1
Role of COUP-TFI during retinoic acid-induced differentiation of P19 cells to endodermal cells.
Pickens BS, Teets BW, Soprano KJ, Soprano DR.
J Cell Physiol 228(4):791-800. doi: 10.1002/jcp.24228. 2013
8MTTP, NR2F1
NR2F1 disrupts synergistic activation of the MTTP gene transcription by HNF-4α and HNF-1α.
Dai K, Hussain MM.
J Lipid Res 53(5):901-8. doi: 10.1194/jlr.M025130. Epub 2012 Feb 22. 2012
9NR2F1, RND2
COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression.
Alfano C, Viola L, Heng JI, Pirozzi M, Clarkson M, Flore G, De Maio A, Schedl A, Guillemot F, Studer M.
Development. 138(21):4685-97. 2011
10NR2F1
Thyroid hormone and COUP-TF1 regulate kallikrein-binding protein (KBP) gene expression.
Liu YY, Nakatani T, Kogai T, Mody K, Brent GA.
Endocrinology 152(3):1143-53. doi: 10.1210/en.2010-0580. Epub 2011 Jan 25. 2011
11CYP3A4, NR1I2, NR2F1, NR2F2, THRA, THRB
Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element binding.
Istrate MA, Nussler AK, Eichelbaum M, Burk O.
Biochem Biophys Res Commun 393(4):688-93. Epub 2010 Feb 18.PMID: 20171174 2010
12NR2F1, NR2F2
COUP-TFs regulate eye development by controlling factors essential for optic vesicle morphogenesis.
Tang K, Xie X, Park JI, Jamrich M, Tsai S, Tsai MJ.
Development 137(5):725-34.PMID: 20147377 2010
13NR2F1
Area-specific temporal control of corticospinal motor neuron differentiation by COUP-TFI.
Tomassy GS, De Leonibus E, Jabaudon D, Lodato S, Alfano C, Mele A, Macklis JD, Studer M.
Proc Natl Acad Sci U S A 107(8):3576-81. Epub 2010 Feb 2.PMID: 20133588 2010
14NR2F1, NR2F2
COUP-TFI and -TFII nuclear receptors are expressed in amacrine cells and play roles in regulating the differentiation of retinal progenitor cells.
Inoue M, Iida A, Satoh S, Kodama T, Watanabe S.
Exp Eye Res 90(1):49-56. Epub 2009 Sep 17.PMID: 19766631 2010
15ERN2, MTTP, NR2F1
NR2F1 and IRE1beta suppress microsomal triglyceride transfer protein expression and lipoprotein assembly in undifferentiated intestinal epithelial cells.
Dai K, Khatun I, Hussain MM.
Arterioscler Thromb Vasc Biol 30(3):568-74. doi: 10.1161/ATVBAHA.109.198135. Epub 2009 Dec 10. 2010
16NR2F1, TNFAIP8
A chicken ovalbumin upstream promoter transcription factor I (COUP-TFI) complex represses expression of the gene encoding tumor necrosis factor alpha-induced protein 8 (TNFAIP8).
Zhang LJ, Liu X, Gafken PR, Kioussi C, Leid M.
J Biol Chem 284(10):6156-68. Epub 2008 Dec 26. 2009
17NR2F1
COUP-TFI modulates estrogen signaling and influences proliferation, survival and migration of breast cancer cells.
Le Dily F, Métivier R, Guéguen MM, Le Péron C, Flouriot G, Tas P, Pakdel F.
Breast Cancer Res Treat 110(1):69-83. Epub 2007 Aug 3. 2008
18NR2F1
COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling.
Faedo A, Tomassy GS, Ruan Y, Teichmann H, Krauss S, Pleasure SJ, Tsai SY, Tsai MJ, Studer M, Rubenstein JL.
Cereb Cortex 18(9):2117-31. Epub 2007 Dec 28.PMID: 18165280 2008
19NR2F1
Genotype-dependent activation or repression of HBV enhancer II by transcription factor COUP-TF1.
Fischer SF, Schmidt K, Fiedler N, Glebe D, Schüttler C, Sun J, Gerlich WH, Repp R, Schaefer S.
World J Gastroenterol 12(37):6054-8. 2006
20NR2F1
COUP-TFI is required for the formation of commissural projections in the forebrain by regulating axonal growth.
Armentano M, Filosa A, Andolfi G, Studer M.
Development 133(21):4151-62. Epub 2006 Oct 4.PMID: 17021036 2006
21CYP11A1, CYP11B1, CYP11B2, CYP17A1D, CYP19A1, GATA4, NR0B1, NR2F1, NR2F2, NR5A1, PCNA, COPS2
DAX1 and its network partners: exploring complexity in development.
Clipsham R, McCabe ER.
Mol Genet Metab 80(1-2):81-120. 2003
22MAPK1, NR2F1
Formation of an hER alpha-COUP-TFI complex enhances hER alpha AF-1 through Ser118 phosphorylation by MAPK.
Métivier R, Gay FA, Hübner MR, Flouriot G, Salbert G, Gannon F, Kah O, Pakdel F.
EMBO J. 21(13):3443-53. 2002
23CALR, NKX2-5, NR2F1
COUP-TF1 antagonizes Nkx2.5-mediated activation of the calreticulin gene during cardiac development.
Guo L, Lynch J, Nakamura K, Fliegel L, Kasahara H, Izumo S, Komuro I, Agellon LB, Michalak M.
J Biol Chem 276(4):2797-801. 2001
24NR2F1, NR2F6
Nuclear orphan receptors regulate transcription of the gene for the human luteinizing hormone receptor.
Zhang Y, Dufau ML.
J Biol Chem 275(4):2763-70. 2000
25NR2F1
The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERRalpha1.
Klinge CM, Kaur K, Swanson HI.
Arch Biochem Biophys. 373(1):163-74. 2000
26NR2F1
Transcription activation by the orphan nuclear receptor, chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI). Definition of the domain involved in the glucocorticoid response of the phosphoenolpyruvate carboxykinase gene
Sugiyama T, Wang JC, Scott DK, Granner DK.
J Biol Chem. 275(5):3446-54. 2000
27NR2F1, NR2F6, NR4A2
Identification of nuclear orphan receptors as regulators of expression of a neurotransmitter receptor gene.
Chew LJ, Huang F, Boutin JM, Gallo V.
J Biol Chem 274(41):29366-75. 1999
28COPS2, NR2F1
Alien, a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily.
Dressel U, Thormeyer D, Altincicek B, Paululat A, Eggert M, Schneider S, Tenbaum SP, Renkawitz R, Baniahmad A.
Mol Cell Biol 19(5):3383-94. 1999
29NR2F1
COUP-TF and Sp1 interact and cooperate in the transcriptional activation of the human immunodeficiency virus type 1 long terminal repeat in human microglial cells.
Rohr O, Aunis D, Schaeffer E.
J Biol Chem. 272(49):31149-55. 1997
30NR2F1
Chicken ovalbumin upstream promoter-transcription factor interacts with estrogen receptor, binds to estrogen response elements and half-sites, and inhibits estrogen-induced gene expression.
Klinge CM, Silver BF, Driscoll MD, Sathya G, Bambara RA, Hilf R.
J Biol Chem. 272(50):31465-74. 1997
31NR2F1, NR2F2
Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes.
Qiu Y, et al.
Genomics 29 : 240-246. 1995
32NR2F1
Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II).
Ing NH, Beekman JM, Tsai SY, Tsai MJ, O'Malley BW.
J Biol Chem. 267(25):17617-23. 1992
33NR2F1
Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling.
Kliewer SA, Umesono K, Heyman RA, Mangelsdorf DJ, Dyck JA, Evans RM.
Proc Natl Acad Sci U S A. 89(4):1448-52. 1992
34NR2F1
Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein.
Berrodin TJ, Marks MS, Ozato K, Linney E, Lazar MA.
Mol Endocrinol. 6(9):1468-78. 1992
35NR2F1, NR2F6
Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related to each other.
Miyajima N, et al.
Nucleic Acids Res 16 : 11057-11074. 1988