Citations for
1CCAR1, NR1I3
Cell Cycle and Apoptosis Regulator 1, CCAR1, Regulates Enhancer-Dependent Nuclear Receptor CAR Transactivation.
Kanno Y, Zhao S, Yamashita N, Saito N, Ujiie A, Iijima R, Kikawa N, Nemoto K, Inouye Y.
Mol Pharmacol 95(1):120-126. doi: 10.1124/mol.118.114272. Epub 2018 Nov 5. 2019
2DNAJC7, HSPA4, NR1I3
Coordinated regulation of nuclear receptor CAR by CCRP/DNAJC7, HSP70 and the ubiquitin-proteasome system.
Timsit YE, Negishi M.
PLoS One 9(5):e96092. doi: 10.1371/journal.pone.0096092. eCollection 2014. 2014
3NR1I3
Signaling control of the constitutive androstane receptor (CAR).
Yang H, Wang H.
Protein Cell 5(2):113-23. doi: 10.1007/s13238-013-0013-0. Epub 2014 Jan 29. 2014
4NR1I3, PSMC5
Proteasomal interaction as a critical activity modulator of the human constitutive androstane receptor.
Chen T, Laurenzana EM, Coslo DM, Chen F, Omiecinski CJ.
Biochem J 458(1):95-107. doi: 10.1042/BJ20130685. 2014
5DNAJC7, MDM2, NR1I3, TP53
Co-chaperon DnaJC7/TPR2 enhances p53 stability and activity through blocking the complex formation between p53 and MDM2.
Kubo N, Wu D, Yoshihara Y, Sang M, Nakagawara A, Ozaki T.
Biochem Biophys Res Commun 430(3):1034-9. doi: 10.1016/j.bbrc.2012.11.121. Epub 2012 Dec 21. 2013
6NR1I3
The human constitutive androstane receptor promotes the differentiation and maturation of hepatic-like cells.
Chen F, Zamule SM, Coslo DM, Chen T, Omiecinski CJ.
Dev Biol 384(2):155-65. doi: 10.1016/j.ydbio.2013.10.012. Epub 2013 Oct 18. 2013
7NR1I3
An update on the constitutive androstane receptor (CAR).
Molnár F, Küblbeck J, Jyrkkärinne J, Prantner V, Honkakoski P.
Drug Metabol Drug Interact 28(2):79-93. doi: 10.1515/dmdi-2013-0009. Review. 2013
8NR1I3
Identification and characterization of novel alternative splice variants of human constitutive androstane receptor in liver samples of Koreans and Caucasians.
Choi EJ, Jang YJ, Cha EY, Shin JG, Lee SS.
Drug Metab Dispos 41(4):888-96. doi: 10.1124/dmd.112.049791. Epub 2013 Feb 1. 2013
9DEL9Q34, EHMT1, KMT2C, MBD5, NR1I3, SMARCB1
Disruption of an EHMT1-Associated Chromatin-Modification Module Causes Intellectual Disability.
Kleefstra T, Kramer JM, Neveling K, Willemsen MH, Koemans TS, Vissers LE, Wissink-Lindhout W, Fenckova M, van den Akker WM, Kasri NN, Nillesen WM, Prescott T, Clark RD, Devriendt K, van Reeuwijk J, de Brouwer AP, Gilissen C, Zhou H, Brunner HG, Veltman JA, Schenck A, van Bokhoven H.
Am J Hum Genet 91(1):73-82. Epub 2012 Jun 21. 2012
10NR0B1, NR1I3
The orphan nuclear receptor DAX-1 functions as a potent corepressor of the constitutive androstane receptor (NR1I3).
Laurenzana EM, Chen T, Kannuswamy M, Sell BE, Strom SC, Li Y, Omiecinski CJ.
Mol Pharmacol 82(5):918-28. doi: 10.1124/mol.112.080721. Epub 2012 Aug 15. 2012
11DDX54, NR1I3
DP97, a DEAD box DNA/RNA helicase, is a target gene-selective co-regulator of the constitutive androstane receptor.
Kanno Y, Serikawa T, Inajima J, Inouye Y.
Biochem Biophys Res Commun 426(1):38-42. doi: 10.1016/j.bbrc.2012.08.027. 2012
12ABCC4, NR1I3
Changes of organic anion transporter MRP4 and related nuclear receptors in human obstructive cholestasis.
Chai J, Luo D, Wu X, Wang H, He Y, Li Q, Zhang Y, Chen L, Peng ZH, Xiao T, Wang R, Chen W.
J Gastrointest Surg 15(6):996-1004. doi: 10.1007/s11605-011-1473-2. Epub 2011 Feb 26. 2011
13NR1I3
Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.
Tolson AH, Wang H.
Adv Drug Deliv Rev 62(13):1238-49. doi: 10.1016/j.addr.2010.08.006. Epub 2010 Aug 17. Review. 2010
14NR1I3
Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease.
Dong B, Saha PK, Huang W, Chen W, Abu-Elheiga LA, Wakil SJ, Stevens RD, Ilkayeva O, Newgard CB, Chan L, Moore DD.
Proc Natl Acad Sci U S A 106(44):18831-6. doi: 10.1073/pnas.0909731106. Epub 2009 Oct 22. 2009
15NR1I3
The nuclear receptor CAR (NR1I3) regulates serum triglyceride levels under conditions of metabolic stress.
Maglich JM, Lobe DC, Moore JT.
J Lipid Res 50(3):439-45. doi: 10.1194/jlr.M800226-JLR200. Epub 2008 Oct 21. 2009
16NR1I3
Expression of hepatocyte transporters and nuclear receptors in children with early and late-stage biliary atresia.
Chen HL, Liu YJ, Chen HL, Wu SH, Ni YH, Ho MC, Lai HS, Hsu WM, Hsu HY, Tseng HC, Jeng YM, Chang MH.
Pediatr Res 63(6):667-73. doi: 10.1203/PDR.0b013e318170a6b5. 2008
17NR1I3
Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha.
Ding X, Lichti K, Kim I, Gonzalez FJ, Staudinger JL.
J Biol Chem 281(36):26540-51. Epub 2006 Jul 5. 2006
18NR1I3
Functional analysis of four naturally occurring variants of human constitutive androstane receptor.
Ikeda S, Kurose K, Jinno H, Sai K, Ozawa S, Hasegawa R, Komamura K, Kotake T, Morishita H, Kamakura S, Kitakaze M, Tomoike H, Tamura T, Yamamoto N, Kunitoh H, Yamada Y, Ohe Y, Shimada Y, Shirao K, Kubota K, Minami H, Ohtsu A, Yoshida T, Saijo N, Saito Y, Sawada J.
Mol Genet Metab 86(1-2):314-9. Epub 2005 Jun 28. 2005
19NCOA6, NR1I3
Characterization of activating signal cointegrator-2 as a novel transcriptional coactivator of the xenobiotic nuclear receptor constitutive androstane receptor.
Choi E, Lee S, Yeom SY, Kim GH, Lee JW, Kim SW.
Mol Endocrinol 19(7):1711-9. Epub 2005 Mar 10. 2005
20DNAJC7, NR1I3
Cytoplasmic accumulation of the nuclear receptor CAR by a tetratricopeptide repeat protein in HepG2 cells.
Kobayashi K, Sueyoshi T, Inoue K, Moore R, Negishi M.
Mol Pharmacol 64(5):1069-75. 2003
21ABLIM1, COX7B, DYNC1I1, ITGB1BP1, IDI1, ILVBL, KIAA0494, LCMT1, MADD, MAPK10, NAT8, NR1I3, RSL1D1, DDX23, RAB2A, RARS, RNF10, TRIM24, TRPV2
High-throughput imaging of brain gene expression.
Brown VM, Ossadtchi A, Khan AH, Cherry SR, Leahy RM, Smith DJ.
Genome Res 12(2):244-54. 2002
22NR1I3
A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements.
Baes M, et al.
Mol Cell Biol 14(3):1544-51 1994