| 1 | ABCA1, EEPD1, NR1H2, NR1H3
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| EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux.
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| Nelson JK, Koenis DS, Scheij S, Cook EC, Moeton M, Santos A, Lobaccaro JA, Baron S, Zelcer N.
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| Arterioscler Thromb Vasc Biol 37(3):423-432. doi: 10.1161/ATVBAHA.116.308434. Epub 2017 Jan 12.
2017
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| 2 | NR1H2, NR1H3, PIAS1
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| A role for protein inhibitor of activated STAT1 (PIAS1) in lipogenic regulation through SUMOylation-independent suppression of liver X receptors.
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| Zhang Y, Gan Z, Huang P, Zhou L, Mao T, Shao M, Jiang X, Chen Y, Ying H, Cao M, Li J, Li J, Zhang WJ, Yang L, Liu Y.
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| J Biol Chem 287(45):37973-85. doi: 10.1074/jbc.M112.403139. Epub 2012 Sep 11.
2012
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| 3 | CIDEA, NR1H2, NR1H3
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| CIDEA interacts with liver X receptors in white fat cells.
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| Kulyté A, Pettersson AT, Antonson P, Stenson BM, Langin D, Gustafsson JA, Staels B, Rydén M, Arner P, Laurencikiene J.
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| FEBS Lett 585(5):744-8. Epub 2011 Feb 22.
2011
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| 4 | ABCA1, NR1H2
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| Liver X receptor beta (LXRbeta) interacts directly with ATP-binding cassette A1 (ABCA1) to promote high density lipoprotein formation during acute cholesterol accumulation.
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| Hozoji-Inada M, Munehira Y, Nagao K, Kioka N, Ueda K.
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| J Biol Chem 286(22):20117-24. Epub 2011 Apr 20.
2011
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| 5 | NR1H2, NR1H3
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| Both liver-X receptor (LXR) isoforms control energy expenditure by regulating brown adipose tissue activity.
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| Korach-André M, Archer A, Barros RP, Parini P, Gustafsson JÅ.
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| Proc Natl Acad Sci U S A 108(1):403-8. Epub 2010 Dec 20.
2011
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| 6 | NR1H2, NR1H3
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| Genetic variation within the NR1H2 gene encoding liver X receptor β associates with insulin secretion in subjects at increased risk for type 2 diabetes.
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| Ketterer C, Müssig K, Machicao F, Stefan N, Fritsche A, Häring HU, Staiger H.
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| J Mol Med (Berl) 89(1):75-81. Epub 2010 Nov 2.
2011
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| 7 | MID1IP1, NR1H2, NR1H3
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| Identification of MIG12 as a mediator for stimulation of lipogenesis by LXR activation.
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| Inoue J, Yamasaki K, Ikeuchi E, Satoh S, Fujiwara Y, Nishimaki-Mogami T, Shimizu M, Sato R.
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| Mol Endocrinol 25(6):995-1005. doi: 10.1210/me.2011-0070. Epub 2011 Apr 7.
2011
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| 8 | NR1H2, NR1H3
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| Expression of liver X receptors in pregnancies complicated by preeclampsia.
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| Weedon-Fekjær MS, Johnsen GM, Anthonisen EH, Sugulle M, Nebb HI, Duttaroy AK, Staff AC.
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| Placenta 31(9):818-24. Epub 2010 Jul 22.
2010
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| 9 | NR1H2, NR1H3
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| LXR{beta} is the dominant LXR subtype in skeletal muscle regulating lipogenesis and cholesterol efflux.
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| Hessvik NP, Boekschoten MV, Baltzersen MA, Kersten S, Xu X, Andersén H, Rustan AC, Thoresen GH.
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| Am J Physiol Endocrinol Metab 298(3):E602-13. Epub 2009 Dec 8.
2010
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| 10 | NR1H2, NR1H3
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| Liver X receptor in cholesterol metabolism.
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| Zhao C, Dahlman-Wright K.
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| J Endocrinol 204(3):233-40. Epub 2009 Oct 16. Review.
2010
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| 11 | NR1H2
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| A liver X receptor (LXR)-beta alternative splicing variant (LXRBSV) acts as an RNA co-activator of LXR-beta.
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| Hashimoto K, Ishida E, Matsumoto S, Shibusawa N, Okada S, Monden T, Satoh T, Yamada M, Mori M.
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| Biochem Biophys Res Commun 390(4):1260-5. Epub 2009 Oct 28.
2009
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| 12 | NR1H2, NR1H3
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| Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells.
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| Sacchetti P, Sousa KM, Hall AC, Liste I, Steffensen KR, Theofilopoulos S, Parish CL, Hazenberg C, Richter LA, Hovatta O, Gustafsson JA, Arenas E.
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| Cell Stem Cell 5(4):409-19.
2009
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| 13 | NR1H2, NR1H3
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| Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR.
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| A-Gonzalez N, Bensinger SJ, Hong C, Beceiro S, Bradley MN, Zelcer N, Deniz J, Ramirez C, Díaz M, Gallardo G, de Galarreta CR, Salazar J, Lopez F, Edwards P, Parks J, Andujar M, Tontonoz P, Castrillo A.
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| Immunity 31(2):245-58. Epub 2009 Jul 30.
2009
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| 14 | NR1H2, NR1H3
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| Liver X receptors are negative regulators of cardiac hypertrophy via suppressing NF-kappaB signalling.
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| Wu S, Yin R, Ernest R, Li Y, Zhelyabovska O, Luo J, Yang Y, Yang Q.
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| Cardiovasc Res 84(1):119-26. Epub 2009 Jun 1.
2009
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| 15 | NR1H2
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| Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia.
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| Kim HJ, Fan X, Gabbi C, Yakimchuk K, Parini P, Warner M, Gustafsson JA.
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| Proc Natl Acad Sci U S A 105(6):2094-9. Epub 2008 Jan 31. 2008
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| 16 | NR1H2,NR1H3
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| Liver X receptor stimulates cholesterol efflux and inhibits expression of proinflammatory mediators in human airway smooth muscle cells.
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| Delvecchio CJ, Bilan P, Radford K, Stephen J, Trigatti BL, Cox G, Parameswaran K, Capone JP.
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| Mol Endocrinol 21(6):1324-34. Epub 2007 Apr 3. 2007
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| 17 | NR1H3, NR1H2
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| Liver X receptor gene polymorphisms and adipose tissue expression levels in obesity.
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| Dahlman I, Nilsson M, Jiao H, Hoffstedt J, Lindgren CM, Humphreys K, Kere J, Gustafsson JA, Arner P, Dahlman-Wright K.
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| Pharmacogenet Genomics 16(12):881-9. 2006
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| 18 | NR1H2, NR1H3
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| LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function.
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| Gerin I, Dolinsky VW, Shackman JG, Kennedy RT, Chiang SH, Burant CF, Steffensen KR, Gustafsson JA, MacDougald OA.
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| J Biol Chem 280(24):23024-31. Epub 2005 Apr 13. 2005
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| 19 | ACVRL1, NR1H2
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| Regulation of ALK-1 signaling by the nuclear receptor LXRbeta.
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| Mo J, Fang SJ, Chen W, Blobe GC.
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| J Biol Chem 277(52):50788-94. 2002
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| 20 | NR1H3, NR1H2
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| Identification of macrophage liver X receptors as inhibitors of atherosclerosis.
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| Tangirala RK, Bischoff ED, Joseph SB, Wagner BL, Walczak R, Laffitte BA, Daige CL, Thomas D, Heyman RA, Mangelsdorf DJ, Wang X, Lusis AJ, Tontonoz P, Schulman IG.
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| Proc Natl Acad Sci U S A 99(18):11896-901. Epub 2002 Aug 22. 2002
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| 21 | NR1H2, NR1H3, SREBF1
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| Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter.
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| Yoshikawa T, Shimano H, Amemiya-Kudo M, Yahagi N, Hasty AH, Matsuzaka T, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Kimura S, Ishibashi S, Yamada N.
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| Mol Cell Biol 21(9):2991-3000. 2001
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| 22 | NR1H2
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| Assignment of the human ubiquitous receptor gene (UNR) to 19q13.3 using fluorescence in situ hybridization.
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| Le Beau MM, et al.
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| Genomics 26 : 166-168. 1995
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| 23 | NR1H2
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| Ubiquitous receptor : a receptor that modulates gene activation by retinoic acid and thyroid hormone receptors.
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| Song C, et al.
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| Proc Natl Acad Sci U S A 91 : 10809-10813. 1994
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| 24 | NR1H2
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| NER, a new member of the gene family encoding the human steroid hormone nuclear receptor.
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| Shinar DM, et al.
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| Gene 147(2):273-6 1994
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