Citations for
1CIDEA, NR1H2, NR1H3
CIDEA interacts with liver X receptors in white fat cells.
Kulyt A, Pettersson AT, Antonson P, Stenson BM, Langin D, Gustafsson JA, Staels B, Rydn M, Arner P, Laurencikiene J.
FEBS Lett 585(5):744-8. Epub 2011 Feb 22. 2011
2ABCA1, NR1H2
Liver X receptor beta (LXRbeta) interacts directly with ATP-binding cassette A1 (ABCA1) to promote high density lipoprotein formation during acute cholesterol accumulation.
Hozoji-Inada M, Munehira Y, Nagao K, Kioka N, Ueda K.
J Biol Chem 286(22):20117-24. Epub 2011 Apr 20. 2011
3NR1H2, NR1H3
Both liver-X receptor (LXR) isoforms control energy expenditure by regulating brown adipose tissue activity.
Korach-Andr M, Archer A, Barros RP, Parini P, Gustafsson J.
Proc Natl Acad Sci U S A 108(1):403-8. Epub 2010 Dec 20. 2011
4NR1H2, NR1H3
Genetic variation within the NR1H2 gene encoding liver X receptor β associates with insulin secretion in subjects at increased risk for type 2 diabetes.
Ketterer C, Mssig K, Machicao F, Stefan N, Fritsche A, Hring HU, Staiger H.
J Mol Med (Berl) 89(1):75-81. Epub 2010 Nov 2. 2011
5NR1H2, NR1H3
Expression of liver X receptors in pregnancies complicated by preeclampsia.
Weedon-Fekjr MS, Johnsen GM, Anthonisen EH, Sugulle M, Nebb HI, Duttaroy AK, Staff AC.
Placenta 31(9):818-24. Epub 2010 Jul 22. 2010
6NR1H2, NR1H3
LXR{beta} is the dominant LXR subtype in skeletal muscle regulating lipogenesis and cholesterol efflux.
Hessvik NP, Boekschoten MV, Baltzersen MA, Kersten S, Xu X, Andersn H, Rustan AC, Thoresen GH.
Am J Physiol Endocrinol Metab 298(3):E602-13. Epub 2009 Dec 8. 2010
7NR1H2, NR1H3
Liver X receptor in cholesterol metabolism.
Zhao C, Dahlman-Wright K.
J Endocrinol 204(3):233-40. Epub 2009 Oct 16. Review. 2010
8NR1H2
A liver X receptor (LXR)-beta alternative splicing variant (LXRBSV) acts as an RNA co-activator of LXR-beta.
Hashimoto K, Ishida E, Matsumoto S, Shibusawa N, Okada S, Monden T, Satoh T, Yamada M, Mori M.
Biochem Biophys Res Commun 390(4):1260-5. Epub 2009 Oct 28. 2009
9NR1H2, NR1H3
Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells.
Sacchetti P, Sousa KM, Hall AC, Liste I, Steffensen KR, Theofilopoulos S, Parish CL, Hazenberg C, Richter LA, Hovatta O, Gustafsson JA, Arenas E.
Cell Stem Cell 5(4):409-19. 2009
10NR1H2, NR1H3
Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR.
A-Gonzalez N, Bensinger SJ, Hong C, Beceiro S, Bradley MN, Zelcer N, Deniz J, Ramirez C, Daz M, Gallardo G, de Galarreta CR, Salazar J, Lopez F, Edwards P, Parks J, Andujar M, Tontonoz P, Castrillo A.
Immunity 31(2):245-58. Epub 2009 Jul 30. 2009
11NR1H2, NR1H3
Liver X receptors are negative regulators of cardiac hypertrophy via suppressing NF-kappaB signalling.
Wu S, Yin R, Ernest R, Li Y, Zhelyabovska O, Luo J, Yang Y, Yang Q.
Cardiovasc Res 84(1):119-26. Epub 2009 Jun 1. 2009
12NR1H2
Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia.
Kim HJ, Fan X, Gabbi C, Yakimchuk K, Parini P, Warner M, Gustafsson JA.
Proc Natl Acad Sci U S A 105(6):2094-9. Epub 2008 Jan 31. 2008
13NR1H2,NR1H3
Liver X receptor stimulates cholesterol efflux and inhibits expression of proinflammatory mediators in human airway smooth muscle cells.
Delvecchio CJ, Bilan P, Radford K, Stephen J, Trigatti BL, Cox G, Parameswaran K, Capone JP.
Mol Endocrinol 21(6):1324-34. Epub 2007 Apr 3. 2007
14NR1H3, NR1H2
Liver X receptor gene polymorphisms and adipose tissue expression levels in obesity.
Dahlman I, Nilsson M, Jiao H, Hoffstedt J, Lindgren CM, Humphreys K, Kere J, Gustafsson JA, Arner P, Dahlman-Wright K.
Pharmacogenet Genomics 16(12):881-9. 2006
15NR1H2, NR1H3
LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function.
Gerin I, Dolinsky VW, Shackman JG, Kennedy RT, Chiang SH, Burant CF, Steffensen KR, Gustafsson JA, MacDougald OA.
J Biol Chem 280(24):23024-31. Epub 2005 Apr 13. 2005
16ACVRL1, NR1H2
Regulation of ALK-1 signaling by the nuclear receptor LXRbeta.
Mo J, Fang SJ, Chen W, Blobe GC.
J Biol Chem 277(52):50788-94. 2002
17NR1H3, NR1H2
Identification of macrophage liver X receptors as inhibitors of atherosclerosis.
Tangirala RK, Bischoff ED, Joseph SB, Wagner BL, Walczak R, Laffitte BA, Daige CL, Thomas D, Heyman RA, Mangelsdorf DJ, Wang X, Lusis AJ, Tontonoz P, Schulman IG.
Proc Natl Acad Sci U S A 99(18):11896-901. Epub 2002 Aug 22. 2002
18NR1H2, NR1H3, SREBF1
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter.
Yoshikawa T, Shimano H, Amemiya-Kudo M, Yahagi N, Hasty AH, Matsuzaka T, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Kimura S, Ishibashi S, Yamada N.
Mol Cell Biol 21(9):2991-3000. 2001
19NR1H2
Assignment of the human ubiquitous receptor gene (UNR) to 19q13.3 using fluorescence in situ hybridization.
Le Beau MM, et al.
Genomics 26 : 166-168. 1995
20NR1H2
Ubiquitous receptor : a receptor that modulates gene activation by retinoic acid and thyroid hormone receptors.
Song C, et al.
Proc Natl Acad Sci U S A 91 : 10809-10813. 1994
21NR1H2
NER, a new member of the gene family encoding the human steroid hormone nuclear receptor.
Shinar DM, et al.
Gene 147(2):273-6 1994