| 1 | NQO1
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| NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β /Smad signaling pathways in diabetic nephropathy
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| Qiu D, Song S, Chen N, Bian Y, Yuan C, Zhang W, Duan H, Shi Y.
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| Cell Signal. Aug;108:110712. doi: 10.1016/j.cellsig.2023.110712. Epub 2023 May 15. 2023
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| 2 | FOS, NQO1
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| NQO1 regulates cell cycle progression at the G2/M phase
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| Oh ET, Kim HG, Kim CH, Lee J, Kim C, Lee JS, Cho Y, Park HJ.
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| Theranostics. Jan 10;13(3):873-895. doi: 10.7150/thno.77444. 2023
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| 3 | NQO1, SREBF1
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| The NQO1/p53/SREBP1 axis promotes hepatocellular carcinoma progression and metastasis by regulating Snail stability.
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| Wang X, Liu Y, Han A, Tang C, Xu R, Feng L, Yang Y, Chen L, Lin Z.
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| Oncogene. Nov;41(47):5107-5120. doi: 10.1038/s41388-022-02477-6. Epub 2022 Oct 17. 2022
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| 4 | NQO1
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| The diverse functionality of NQO1 and its roles in redox control.
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| Ross D, Siegel D.
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| Redox Biol. May;41:101950. doi: 10.1016/j.redox.2021.101950. Epub 2021 Mar 20. 2021
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| 5 | NQO1, SIRT1
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| NQO1 Binds and Supports SIRT1 Function.
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| Tsvetkov P, Adler J, Strobelt R, Adamovich Y, Asher G, Reuven N, Shaul Y.
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| Front Pharmacol. Jun 21;12:671929. doi: 10.3389/fphar.2021.671929. 2021
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| 6 | NQO1
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| Akt Phosphorylates NQO1 and Triggers its Degradation, Abolishing Its Antioxidative Activities in Parkinson's Disease.
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| Luo S, Kang SS, Wang ZH, Liu X, Day JX, Wu Z, Peng J, Xiang D, Springer W, Ye K.
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| J Neurosci. Sep 11;39(37):7291-7305. doi: 10.1523/JNEUROSCI.0625-19.2019. Epub 2019 Jul 29. 2019
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| 7 | NQO1, SIRT2
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| NQO1 regulates mitotic progression and response to mitotic stress through modulating SIRT2 activity.
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| Kang HJ, Song HY, Ahmed MA, Guo Y, Zhang M, Chen C, Cristofanilli M, Horiuchi D, Vassilopoulos A.
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| Free Radic Biol Med 126:358-371. doi: 10.1016/j.freeradbiomed.2018.08.009. Epub 2018 Aug 13.
2018
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| 8 | NQO1
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| NQO1 inhibits proteasome-mediated degradation of HIF-1α.
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| Oh ET, Kim JW, Kim JM, Kim SJ, Lee JS, Hong SS, Goodwin J, Ruthenborg RJ, Jung MG, Lee HJ, Lee CH, Park ES, Kim C, Park HJ.
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| Nat Commun. Dec 14;7:13593. doi: 10.1038/ncomms13593. 2016
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| 9 | NQO1
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| Clinical implications of high NQO1 expression in breast cancers.
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| Yang Y, Zhang Y, Wu Q, Cui X, Lin Z, Liu S, Chen L.
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| J Exp Clin Cancer Res 33:14. doi: 10.1186/1756-9966-33-14.
2014
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| 10 | NQO1
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| NQO1 prevents radiation-induced aneuploidy by interacting with Aurora-A.
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| Park MT, Oh ET, Song MJ, Lee H, Choi EK, Park HJ.
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| Carcinogenesis 34(11):2470-85. doi: 10.1093/carcin/bgt225. Epub 2013 Jun 26.
2013
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| 11 | NQO1, PPARGC1A
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| The protein level of PGC-1α, a key metabolic regulator, is controlled by NADH-NQO1.
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| Adamovich Y, Shlomai A, Tsvetkov P, Umansky KB, Reuven N, Estall JL, Spiegelman BM, Shaul Y.
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| Mol Cell Biol. Jul;33(13):2603-13. doi: 10.1128/MCB.01672-12. Epub 2013 May 6. 2013
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| 12 | NFE2L2, NQO1, SQSTM1
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| Assurance of mitochondrial integrity and mammalian longevity by the p62-Keap1-Nrf2-Nqo1 cascade.
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| Kwon J, Han E, Bui CB, Shin W, Lee J, Lee S, Choi YB, Lee AH, Lee KH, Park C, Obin MS, Park SK, Seo YJ, Oh GT, Lee HW, Shin J.
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| EMBO Rep 13(2):150-6. doi: 10.1038/embor.2011.246.
2012
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| 13 | NQO1
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| NAD(P)H:quinone oxidoreductase 1 (NQO1) localizes to the mitotic spindle in human cells.
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| Siegel D, Kepa JK, Ross D.
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| PLoS One 7(9):e44861. doi: 10.1371/journal.pone.0044861. Epub 2012 Sep 11.
2012
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| 14 | NQO1
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| A mutually inhibitory feedback loop between the 20S proteasome and its regulator, NQO1.
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| Moscovitz O, Tsvetkov P, Hazan N, Michaelevski I, Keisar H, Ben-Nissan G, Shaul Y, Sharon M.
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| Mol Cell 47(1):76-86. doi: 10.1016/j.molcel.2012.05.049.
2012
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| 15 | NQO1, PDLIM4
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| Actin cytoskeleton remodeling by the alternatively spliced isoform of PDLIM4/RIL protein.
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| Guryanova OA, Drazba JA, Frolova EI, Chumakov PM.
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| J Biol Chem 286(30):26849-59. Epub 2011 Jun 2.
2011
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| 16 | EIF4G1, NQO1
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| NAD(P)H quinone-oxydoreductase 1 protects eukaryotic translation initiation factor 4GI from degradation by the proteasome.
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| Alard A, Fabre B, Anesia R, Marboeuf C, Pierre P, Susini C, Bousquet C, Pyronnet S.
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| Mol Cell Biol 30(4):1097-105. Epub 2009 Dec 22.
2010
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| 17 | NQO1
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| The C609T variant of NQO1 is associated with carotid artery plaques in patients with type 2 diabetes.
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| Han SJ, Kang ES, Kim HJ, Kim SH, Chun SW, Ahn CW, Cha BS, Nam M, Lee HC.
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| Mol Genet Metab 97(1):85-90. Epub 2009 Feb 1.
2009
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| 18 | NQO1
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| NAD(P)H:quinone oxidoreductase 1 NQO1*2 genotype (P187S) is a strong prognostic and predictive factor in breast cancer.
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| Fagerholm R, Hofstetter B, Tommiska J, Aaltonen K, Vrtel R, Syrjkoski K, Kallioniemi A, Kilpivaara O, Mannermaa A, Kosma VM, Uusitupa M, Eskelinen M, Kataja V, Aittomki K, von Smitten K, Heikkil P, Lukas J, Holli K, Bartkova J, Blomqvist C, Bartek J, Nevanlinna H.
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| Nat Genet 40(7):844-53. Epub 2008 May 30. 2008
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| 19 | NQO1
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| The frequencies of NAD(P)H quinone oxidoreductase (NQO1) variant allele in Israeli ethnic groups and the relationship of NQO1*2 to adult acute myeloid leukemia in Israeli patients.
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| Malik E, Cohen SB, Sahar D, Dann EJ, Rund D.
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| Haematologica 91(7):956-9. 2006
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| 20 | NFE2L2, PARK7, NQO1
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| DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2.
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| Clements CM, McNally RS, Conti BJ, Mak TW, Ting JP.
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| Proc Natl Acad Sci U S A 103(41):15091-6. Epub 2006 Oct 2. 2006
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| 21 | NQO1
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| Chromosome band 16q22-linked familial AML: exclusion of candidate genes, and possible disease risk modification by NQO1 polymorphisms.
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| Escher R, Jones A, Hagos F, Carmichael C, Horwitz M, Olopade OI, Scott HS.
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| Genes Chromosomes Cancer 41(3):278-82. 2004
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| 22 | CYP2E1, MPO, NQO1
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| Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia.
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| Krajinovic M, Sinnett H, Richer C, Labuda D, Sinnett D.
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| Int J Cancer 97(2):230-6. 2002
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| 23 | GSTM1, NQO1, NQO2
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| An association between idiopathic Parkinson's disease and polymorphisms of phase II detoxification enzymes: glutathione S-transferase M1 and quinone oxidoreductase 1 and 2.
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| Harada S, Fujii C, Hayashi A, Ohkoshi N.
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| Biochem Biophys Res Commun 288(4):887-92. 2001
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| 24 | NQO1, REXO4
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| Identification and characterization of a novel factor that regulates quinone reductase gene transcriptional activity.
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| Montano MM, Wittmann BM, Bianco NR.
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| J Biol Chem 275(44):34306-13. 2000
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| 25 | NQO1
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| 609 C --> T polymorphism in NAD(P)H:quinone oxidoreductase gene in patients with prostatic adenocarcinoma or benign prostatic hyperplasia.
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| Steiner M, et al.
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| Cancer Lett 135(1):67-71. 1999
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| 26 | NQO1
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| A potential mechanism underlying the increased susceptibility of individuals with a polymorphism in NAD(P)H:quinone oxidoreductase 1 (NQO1) to benzene toxicity.
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| Moran JL, Siegel D, Ross D.
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| Proc Natl Acad Sci U S A 96(14):8150-5. 1999
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| 27 | NQO1
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| Human NAD(P)H:quinone oxidoreductase (NQO1) gene structure and induction by dioxin.
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| Jaiswal AK.
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| Biochemistry 30(44):10647-53.
1991
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| 28 | NQO1
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| Human dioxin-inducible cytosolic NAD(P)H : Menadione oxidoreductase.
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| Jaiswal AK, et al.
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| J Biol Chem 263 : 13572-13578. 1988
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| 29 | APRT, NQO1
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| Further evidence for regional localization of human APRT and DIA4 on chromosome 16.
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| Lavinha J, et al.
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| (HGM7) Cytogenet Cell Genet 37 : 517. 1984
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| 30 | HB-A@, HBA1, HBA2, HBAP1, HBM, HBQ1, HBZ, HBZP, NQO1
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| Regional localization of the human alpha-globin gene to the short arm of chromosome 16 (16p12-pter) using both somatic cell hybrids and in situ hybridization.
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| Barg R, et al.
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| Cytogenet Cell Genet 32 : 252-253. 1982
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| 31 | NQO1
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| Assignment of a human diapharase (DIA4) to chromosome 16.
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| Povey S, et al.
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| Ann Hum Genet 43 : 349-353. 1980
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| 32 | NQO1
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| Assignment of a structural gene for a fourth human diaphorase (DIA4) to chromosome 16 in man-mouse somatic cell hybrids.
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| Grzeschik KH.
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| Hum Genet 53 : 189-193. 1980
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