| 1 | NPPC
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| C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagy.
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| Zhang H, Li C, Liu Q, Li J, Wu H, Xu R, Sun Y, Cheng M, Zhao X, Pan M, Wei Q, Ma B.
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| Elife. Oct 20;12:RP88523. doi: 10.7554/eLife.88523. 2023
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| 2 | NPPC, OSTN
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| Skeletal muscle derived Musclin protects the heart during pathological overload.
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| Nikolaev VO, Müller OJ, Katus HA, El-Armouche A, Kraft T, Springer J, Dobreva G, Wollert KC, Fielitz J, von Haehling S, Kuhn M, Bauersachs J, Heineke J.
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| Nat Commun. Jan 10;13(1):149. doi: 10.1038/s41467-021-27634-5. 2022
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| 3 | NPPC, NPR2
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| Natriuretic peptide type C induces sperm attraction for fertilization in mouse.
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| Kong N, Xu X, Zhang Y, Wang Y, Hao X, Zhao Y, Qiao J, Xia G, Zhang M.
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| Sci Rep. Jan 5;7:39711. doi: 10.1038/srep39711. 2020
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| 4 | NPPC, SSSH
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| Mutations in C-natriuretic peptide (NPPC): a novel cause of autosomal dominant short stature.
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| Hisado-Oliva A, Ruzafa-Martin A, Sentchordi L, Funari MFA, Bezanilla-López C, Alonso-Bernáldez M, Barraza-García J, Rodriguez-Zabala M, Lerario AM, Benito-Sanz S, Aza-Carmona M, Campos-Barros A, Jorge AAL, Heath KE.
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| Genet Med. Jan;20(1):91-97. doi: 10.1038/gim.2017.66. Epub 2017 Jun 28. 2018
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| 5 | MME, NPPC, NPR2
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| Neutral endopeptidase (CD10) is abundantly expressed in the epididymis and localized to a distinct population of epithelial cells--its relevance for CNP degradation.
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| Thong A, Müller D, Feuerstacke C, Mietens A, Stammler A, Middendorff R.
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| Mol Cell Endocrinol 382(1):234-43. doi: 10.1016/j.mce.2013.09.027. Epub 2013 Oct 4.
2014
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| 6 | NPPC, NPR2, NPR3
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| Role of C-type natriuretic peptide signalling in maintaining cartilage and bone function.
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| Peake NJ, Hobbs AJ, Pingguan-Murphy B, Salter DM, Berenbaum F, Chowdhury TT.
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| Osteoarthritis Cartilage. Nov;22(11):1800-7. doi: 10.1016/j.joca.2014.07.018. Epub 2014 Jul 31. 2014
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| 7 | DIS3L2, NPPC
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| Genotype-Phenotype Correlation of 2q37 Deletions Including NPPC Gene Associated with Skeletal Malformations.
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| Tassano E, Buttgereit J, Bader M, Lerone M, Divizia MT, Bocciardi R, Napoli F, Pala G, Sloan-Béna F, Gimelli S, Gimelli G.
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| PLoS One 8(6):e66048. Print 2013.
2013
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| 8 | NPPC, NPR2
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| C-type natriuretic peptide protects the retinal pigment epithelium against advanced glycation end product-induced barrier dysfunction.
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| Dahrouj M, Alsarraf O, Liu Y, Crosson CE, Ablonczy Z.
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| J Pharmacol Exp Ther 344(1):96-102. doi: 10.1124/jpet.112.199307. Epub 2012 Oct 19. 2013
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| 9 | NPPC, NPR2
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| Epidermal growth factor receptor signaling-dependent calcium elevation in cumulus cells is required for NPR2 inhibition and meiotic resumption in mouse oocytes.
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| Wang Y, Kong N, Li N, Hao X, Wei K, Xiang X, Xia G, Zhang M.
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| Endocrinology 154(9):3401-9. doi: 10.1210/en.2013-1133. Epub 2013 Jun 20.
2013
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| 10 | NPPC
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| Characterization of novel 3'untranslated regions and related polymorphisms of the gene NPPC, encoding for the C-type natriuretic peptide.
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| Melaiu O, Facioni MS, Cabiati M, Caruso R, Giannessi D, Landi S, Gemignani F, Del Ry S.
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| Peptides 44:93-9. doi: 10.1016/j.peptides.2013.03.012. Epub 2013 Mar 28.
2013
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| 11 | NPPC, NPR2
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| Molecular control of oocyte meiotic arrest and resumption.
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| Liu L, Kong N, Xia G, Zhang M.
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| Reprod Fertil Dev 25(3):463-71. doi: 10.1071/RD12310. Review.
2013
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| 12 | NPPC, NPR2
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| CNP/NPR2 signaling maintains oocyte meiotic arrest in early antral follicles and is suppressed by EGFR-mediated signaling in preovulatory follicles.
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| Tsuji T, Kiyosu C, Akiyama K, Kunieda T.
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| Mol Reprod Dev 79(11):795-802. doi: 10.1002/mrd.22114. Epub 2012 Sep 28. 2012
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| 13 | NPPC
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| C-type natriuretic peptide stimulates ovarian follicle development.
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| Sato Y, Cheng Y, Kawamura K, Takae S, Hsueh AJ.
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| Mol Endocrinol 26(7):1158-66. doi: 10.1210/me.2012-1027. Epub 2012 May 17.
2012
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| 14 | NPPC, NPR2
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| Estradiol promotes and maintains cumulus cell expression of natriuretic peptide receptor 2 (NPR2) and meiotic arrest in mouse oocytes in vitro.
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| Zhang M, Su YQ, Sugiura K, Wigglesworth K, Xia G, Eppig JJ.
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| Endocrinology 152(11):4377-85. doi: 10.1210/en.2011-1118. Epub 2011 Sep 13.
2011
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| 15 | NPPA, NPPB, NPPC
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| Characterization and functional expression of the natriuretic peptide system in human lens epithelial cells.
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| Cammarata PR, Braun B, Dimitrijevich SD, Pack J.
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| Mol Vis 16:630-8.
2010
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| 16 | NPPC, NPR2
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| Granulosa cell ligand NPPC and its receptor NPR2 maintain meiotic arrest in mouse oocytes.
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| Zhang M, Su YQ, Sugiura K, Xia G, Eppig JJ.
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| Science 330(6002):366-9. doi: 10.1126/science.1193573.
2010
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| 17 | NPPC, NPR2, NPR3
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| C-type natriuretic peptide (CNP) is a bifurcation factor for sensory neurons.
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| Schmidt H, Stonkute A, Jüttner R, Koesling D, Friebe A, Rathjen FG.
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| Proc Natl Acad Sci U S A 106(39):16847-52. Epub 2009 Sep 17.PMID: 19805384 2009
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| 18 | NPPC
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| Distinct downregulation of C-type natriuretic peptide system in human aortic valve stenosis.
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| Peltonen TO, Taskinen P, Soini Y, Rys J, Ronkainen J, Ohtonen P, Satta J, Juvonen T, Ruskoaho H, Leskinen H.
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| Circulation 116(11):1283-9. Epub 2007 Aug 20. 2007
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| 19 | NPPC
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| C-natriuretic peptide: an important regulator of cartilage.
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| Pejchalova K, Krejci P, Wilcox WR.
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| Mol Genet Metab 92(3):210-5. Epub 2007 Aug 6. 2007
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| 20 | DIS3L2, NPPC
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| Overexpression of the C-type natriuretic peptide (CNP) is associated with overgrowth and bone anomalies in an individual with balanced t(2;7) translocation.
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| Bocciardi R, Giorda R, Buttgereit J, Gimelli S, Divizia MT, Beri S, Garofalo S, Tavella S, Lerone M, Zuffardi O, Bader M, Ravazzolo R, Gimelli G.
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| Hum Mutat 28(7):724-31.
2007
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| 21 | NPR2, NPPC
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| Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway.
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| Yasoda A, Komatsu Y, Chusho H, Miyazawa T, Ozasa A, Miura M, Kurihara T, Rogi T, Tanaka S, Suda M, Tamura N, Ogawa Y, Nakao K.
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| Nat Med 10(1):80-6. Epub 2003 Dec 14. 2004
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| 22 | NPPC
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| Molecular cloning and chromosomal assignment of the mouse C-type Natriuretic Peptide (CNP) gene (Nppc) : comparison with the human CNP gene (NPPC).
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| Ogawa Y, et al.
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| Genomics 24 : 383-387. 1994
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