| 1 | NPC1L1, PYY
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| Modulatory role of PYY in transport and metabolism of cholesterol in intestinal epithelial cells.
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| Grenier E, Garofalo C, Delvin E, Levy E.
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| PLoS One 7(7):e40992. doi: 10.1371/journal.pone.0040992. Epub 2012 Jul 23.
2012
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| 2 | NPC1L1
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| Molecular characterization of the NPC1L1 variants identified from cholesterol low absorbers.
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| Wang LJ, Wang J, Li N, Ge L, Li BL, Song BL.
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| J Biol Chem 286(9):7397-408. Epub 2010 Dec 28.
2011
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| 3 | NPC1L1
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| The N-terminal domain of NPC1L1 protein binds cholesterol and plays essential roles in cholesterol uptake.
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| Zhang JH, Ge L, Qi W, Zhang L, Miao HH, Li BL, Yang M, Song BL.
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| J Biol Chem 286(28):25088-97. Epub 2011 May 20.
2011
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| 4 | CDC42, NPC1L1
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| The small GTPase Cdc42 interacts with Niemann-Pick C1-like 1 (NPC1L1) and controls its movement from endocytic recycling compartment to plasma membrane in a cholesterol-dependent manner.
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| Xie C, Li N, Chen ZJ, Li BL, Song BL.
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| J Biol Chem 286(41):35933-42. doi: 10.1074/jbc.M111.270199. Epub 2011 Aug 15.
2011
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| 5 | FLOT1, FLOT2, NPC1L1
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| Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake.
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| Ge L, Qi W, Wang LJ, Miao HH, Qu YX, Li BL, Song BL.
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| Proc Natl Acad Sci U S A 108(2):551-6. doi: 10.1073/pnas.1014434108. Epub 2010 Dec 27.
2011
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| 6 | NPC1L1
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| NPC1L1 and cholesterol transport.
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| Betters JL, Yu L.
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| FEBS Lett 584(13):2740-7. Epub 2010 Mar 19. Review.PMID: 20307540 2010
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| 7 | NPC1L1
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| An NPC1L1 gene promoter variant is associated with autosomal dominant hypercholesterolemia.
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| Martín B, Solanas-Barca M, García-Otín AL, Pampín S, Cofán M, Ros E, Rodríguez-Rey JC, Pocoví M, Civeira F.
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| Nutr Metab Cardiovasc Dis 20(4):236-42. Epub 2009 Sep 11.PMID: 19747803 2010
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| 8 | HNF1A, NPC1L1
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| HNF1alpha and SREBP2 are important regulators of NPC1L1 in human liver.
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| Pramfalk C, Jiang ZY, Cai Q, Hu H, Zhang SD, Han TQ, Eriksson M, Parini P.
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| J Lipid Res 51(6):1354-62.
2010
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| 9 | HMGCR, NPC1, NPC1L1, SCAP
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| Membrane topology of human NPC1L1, a key protein in enterohepatic cholesterol absorption.
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| Wang J, Chu BB, Ge L, Li BL, Yan Y, Song BL.
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| J Lipid Res 50(8):1653-62. Epub 2009 Mar 26.PMID: 19325169 2009
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| 10 | NPC1L1
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| Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8.
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| Tang W, Ma Y, Jia L, Ioannou YA, Davies JP, Yu L.
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| J Lipid Res 50(2):293-300. Epub 2008 Sep 15.PMID: 18796403 2009
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| 11 | NPC1L1
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| Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes.
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| Fahmi S, Yang C, Esmail S, Hobbs HH, Cohen JC.
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| Hum Mol Genet 17(14):2101-7. Epub 2008 Apr 15.
2008
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| 12 | NPC1L1
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| Kinetic imaging of NPC1L1 and sterol trafficking between plasma membrane and recycling endosomes in hepatoma cells.
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| Petersen NH, Faergeman NJ, Yu L, Wüstner D.
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| J Lipid Res 49(9):2023-37. Epub 2008 Jun 3. Erratum in: J Lipid Res. 2008 Nov;49(11):2491.. Faegeman, Nils J [corrected to Faergeman, Nils J 2008
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| 13 | NPC1L1
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| Niemann-pick C1-like 1 mediates alpha-tocopherol transport.
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| Narushima K, Takada T, Yamanashi Y, Suzuki H.
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| Mol Pharmacol 74(1):42-9. Epub 2008 Apr 10.PMID: 18403720 2008
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| 14 | NPC1L1
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| Effect of ezetimibe coadministered with statins in genotype-confirmed heterozygous FH patients.
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| Pisciotta L, Fasano T, Bellocchio A, Bocchi L, Sallo R, Fresa R, Colangeli I, Cantafora A, Calandra S, Bertolini S.
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| Atherosclerosis 194(2):e116-22. Epub 2006 Nov 30. 2007
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| 15 | NPC1, NPC1L1
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| Human NPC1L1 and NPC1 can functionally substitute for the ncr genes to promote reproductive development in C. elegans.
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| Smith MM, Levitan DJ.
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| Biochim Biophys Acta 1770(9):1345-51. Epub 2007 Jun 22.PMID: 17662536 2007
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| 16 | NPC1L1
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| Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels.
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| Cohen JC, Pertsemlidis A, Fahmi S, Esmail S, Vega GL, Grundy SM, Hobbs HH.
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| Proc Natl Acad Sci U S A 103(6):1810-5. Epub 2006 Jan 31. 2006
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| 17 | NPC1L1
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| Niemann-Pick C1 like 1 gene expression is down-regulated by LXR activators in the intestine.
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| Duval C, Touche V, Tailleux A, Fruchart JC, Fievet C, Clavey V, Staels B, Lestavel S.
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| Biochem Biophys Res Commun 340(4):1259-63. Epub 2006 Jan 5. 2006
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| 18 | NPC1L1
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| Sequence variation in NPC1L1 and association with improved LDL-cholesterol lowering in response to ezetimibe treatment.
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| Simon JS, Karnoub MC, Devlin DJ, Arreaza MG, Qiu P, Monks SA, Severino ME, Deutsch P, Palmisano J, Sachs AB, Bayne ML, Plump AS, Schadt EE.
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| Genomics 86(6):648-56. Epub 2005 Nov 16. 2005
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| 19 | NPC1L1
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| Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption.
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| Altmann SW, Davis HR Jr, Zhu LJ, Yao X, Hoos LM, Tetzloff G, Iyer SP, Maguire M, Golovko A, Zeng M, Wang L, Murgolo N, Graziano MP.
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| Science 303(5661):1201-4. 2004
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| 20 | NPC1L1
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| Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis.
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| Davis HR Jr, Zhu LJ, Hoos LM, Tetzloff G, Maguire M, Liu J, Yao X, Iyer SP, Lam MH, Lund EG, Detmers PA, Graziano MP, Altmann SW.
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| J Biol Chem 279(32):33586-92. Epub 2004 Jun 1. 2004
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| 21 | NPC1L1
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| Evidence for a Niemann-pick C (NPC) gene family: identification and characterization of NPC1L1.
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| Davies JP, Levy B, Ioannou YA.
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| Genomics 65(2):137-45. 2000
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| 22 | NPC1, NPC1L1
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| The structure and function of the niemann-pick C1 protein.
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| Ioannou YA.
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| Mol Genet Metab 71(1-2):175-81. 2000
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