Citations for
1CLOCK, NPAS2
NPAS2 Compensates for Loss of CLOCK in Peripheral Circadian Oscillators.
Landgraf D, Wang LL, Diemer T, Welsh DK.
PLoS Genet 12(2):e1005882. doi: 10.1371/journal.pgen.1005882. 2016
2ARNTL, CLOCK, FABP7, NPAS2, NR1D1
Altered Sleep Homeostasis in Rev-erbα Knockout Mice.
Mang GM, La Spada F, Emmenegger Y, Chappuis S, Ripperger JA, Albrecht U, Franken P.
Sleep 39(3):589-601. doi: 10.5665/sleep.5534. 2016
3NPAS2
Direct regulation of diurnal Drd3 expression and cocaine reward by NPAS2.
Ozburn AR, Falcon E, Twaddle A, Nugent AL, Gillman AG, Spencer SM, Arey RN, Mukherjee S, Lyons-Weiler J, Self DW, McClung CA.
Biol Psychiatry 77(5):425-33. doi: 10.1016/j.biopsych.2014.07.030. 2015
4NPAS2, NR0B2
Small heterodimer partner/neuronal PAS domain protein 2 axis regulates the oscillation of liver lipid metabolism.
Lee SM, Zhang Y, Tsuchiya H, Smalling R, Jetten AM, Wang L.
Hepatology 61(2):497-505. doi: 10.1002/hep.27437. 2015
5NPAS2
Silencing NPAS2 promotes cell growth and invasion in DLD-1 cells and correlated with poor prognosis of colorectal cancer.
Xue X, Liu F, Han Y, Li P, Yuan B, Wang X, Chen Y, Kuang Y, Zhi Q, Zhao H.
Biochem Biophys Res Commun 450(2):1058-62. doi: 10.1016/j.bbrc.2014.06.104. 2014
6ARNTL, CLOCK, NPAS2
Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration.
Musiek ES, Lim MM, Yang G, Bauer AQ, Qi L, Lee Y, Roh JH, Ortiz-Gonzalez X, Dearborn JT, Culver JP, Herzog ED, Hogenesch JB, Wozniak DF, Dikranian K, Giasson BI, Weaver DR, Holtzman DM, Fitzgerald GA.
J Clin Invest 123(12):5389-400. doi: 10.1172/JCI70317. 2013
7NPAS2
Dysregulation of Npas2 leads to altered metabolic pathways in a murine knockout model.
O'Neil D, Mendez-Figueroa H, Mistretta TA, Su C, Lane RH, Aagaard KM.
Mol Genet Metab 110(3):378-87. doi: 10.1016/j.ymgme.2013.08.015. 2013
8NPAS2
Effects of NAD(P)H and its derivatives on the DNA-binding activity of NPAS2, a mammalian circadian transcription factor.
Yoshii K, Ishijima S, Sagami I.
Biochem Biophys Res Commun 437(3):386-91. doi: 10.1016/j.bbrc.2013.06.086. 2013
9ARNTL, NPAS2, PER2
Sleep loss reduces the DNA-binding of BMAL1, CLOCK, and NPAS2 to specific clock genes in the mouse cerebral cortex.
Mongrain V, La Spada F, Curie T, Franken P.
PLoS One 6(10):e26622. doi: 10.1371/journal.pone.0026622. 2011
10ARNTL, NPAS2
ARNTL (BMAL1) and NPAS2 gene variants contribute to fertility and seasonality.
Kovanen L, Saarikoski ST, Aromaa A, Lönnqvist J, Partonen T.
PLoS One 5(4):e10007.PMID: 20368993 2010
11NPAS2
NPAS2 deletion impairs responses to restricted feeding but not to metabolic challenges.
Wu X, Wiater MF, Ritter S.
Physiol Behav 99(4):466-71. doi: 10.1016/j.physbeh.2009.12.010. 2010
12NPAS2, PER2
NPAS2 and PER2 are linked to risk factors of the metabolic syndrome.
Englund A, Kovanen L, Saarikoski ST, Haukka J, Reunanen A, Aromaa A, Lönnqvist J, Partonen T.
J Circadian Rhythms 7:5. doi: 10.1186/1740-3391-7-5. 2009
13ARNTL, NPAS2
Effects of mutations in the heme domain on the transcriptional activity and DNA-binding activity of NPAS2.
Ishida M, Ueha T, Sagami I.
Biochem Biophys Res Commun 368(2):292-7. Epub 2008 Jan 28. 2008
14CLOCK, NPAS2
Evidence for an overlapping role of CLOCK and NPAS2 transcription factors in liver circadian oscillators.
Bertolucci C, Cavallari N, Colognesi I, Aguzzi J, Chen Z, Caruso P, Foá A, Tosini G, Bernardi F, Pinotti M.
Mol Cell Biol 28(9):3070-5. Epub 2008 Mar 3.PMID: 18316400 2008
15ARNTL, CLOCK, NPAS2
CLOCK and NPAS2 have overlapping roles in the suprachiasmatic circadian clock.
DeBruyne JP, Weaver DR, Reppert SM.
Nat Neurosci 10(5):543-5. Epub 2007 Apr 8. 2007
16ARNTL,NPAS2,PER2
Three circadian clock genes Per2, Arntl, and Npas2 contribute to winter depression.
Partonen T, Treutlein J, Alpman A, Frank J, Johansson C, Depner M, Aron L, Rietschel M, Wellek S, Soronen P, Paunio T, Koch A, Chen P, Lathrop M, Adolfsson R, Persson ML, Kasper S, Schalling M, Peltonen L, Schumann G.
Ann Med 39(3):229-38. 2007
17MPS3C, LAS1L, LRFN4, SGSM1, HNRPA3, NPAS2, C1orf34
An acetylated 120-kDa lysosomal transmembrane protein is absent from mucopolysaccharidosis IIIC fibroblasts: a candidate molecule for MPS IIIC.
Ausseil J, Landry K, Seyrantepe V, Trudel S, Mazur A, Lapointe F, Pshezhetsky AV.
Mol Genet Metab 87(1):22-31. Epub 2005 Nov 15. 2006
18NPAS2
NPAS2 as a transcriptional regulator of non-rapid eye movement sleep: genotype and sex interactions.
Franken P, Dudley CA, Estill SJ, Barakat M, Thomason R, O'Hara BF, McKnight SL.
Proc Natl Acad Sci U S A 103(18):7118-23. Epub 2006 Apr 24. 2006
19NPAS2
Spectroscopic and DNA-binding characterization of the isolated heme-bound basic helix-loop-helix-PAS-A domain of neuronal PAS protein 2 (NPAS2), a transcription activator protein associated with circadian rhythms.
Mukaiyama Y, Uchida T, Sato E, Sasaki A, Sato Y, Igarashi J, Kurokawa H, Sagami I, Kitagawa T, Shimizu T.
FEBS J 273(11):2528-39. 2006
20ARNTL, NPAS2
NPAS2: a gas-responsive transcription factor.
Dioum EM, Rutter J, Tuckerman JR, Gonzalez G, Gilles-Gonzalez MA, McKnight SL.
Science 298(5602):2385-7. 2002
21CLOCK, NPAS2
Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors.
Rutter J, Reick M, Wu LC, McKnight SL.
Science 293(5529):510-4. 2001
22NPAS2
NPAS2: an analog of clock operative in the mammalian forebrain.
Reick M, Garcia JA, Dudley C, McKnight SL.
Science 293(5529):506-9. 2001
23NPAS2
Impaired cued and contextual memory in NPAS2-deficient mice.
Garcia JA, Zhang D, Estill SJ, Michnoff C, Rutter J, Reick M, Scott K, Diaz-Arrastia R, McKnight SL.
Science 288(5474):2226-30. 2000
24NPAS1, NPAS2
Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system.
Zhou YD, et al.
Proc Natl Acad Sci U S A 94 : 713-718. 1997
25ARNTL, HIF1A, NPAS1, NPAS2
Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway.
Hogenesch JB, Chan WK, Jackiw VH, Brown RC, Gu YZ, Pray-Grant M, Perdew GH, Bradfield CA.
J Biol Chem 272(13):8581-93. 1997