| 1 | NOTCH1, NOTCH2, NOTCH3, NOTCH4
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| Notch and the regulation of osteoclast differentiation and function.
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| Yu J, Canalis E.
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| Bone Jun 8:115474. doi: 10.1016/j.bone.2020.115474. Online ahead of print 2020
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| 2 | NOTCH4, RUNX1
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| Human NOTCH4 is a key target of RUNX1 in megakaryocytic differentiation.
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| Li Y, Jin C, Bai H, Gao Y, Sun S, Chen L, Qin L, Liu PP, Cheng L, Wang QF.
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| Blood Jan 11;131(2):191-201. doi: 10.1182/blood-2017-04-780379. Epub 2017 Nov 3 2018
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| 3 | NOTCH4
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| NOTCH4 regulates colorectal cancer proliferation, invasiveness, and determines clinical outcome of patients.
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| Zhang Z, Bu X, Yang J, Zhu S, He S, Zheng J, Wang W, Chu D.
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| J Cell Physiol. Oct;233(10):6975-6985. doi: 10.1002/jcp.26619. Epub 2018 Apr 25 2018
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| 4 | EFNB2, NOTCH4
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| NOTCH4 signaling controls EFNB2-induced endothelial progenitor cell dysfunction in preeclampsia.
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| Liu X, Luo Q, Zheng Y, Liu X, Hu Y, Liu W, Luo M, Zhao Y, Zou L.
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| Reproduction Jul;152(1):47-55. doi: 10.1530/REP-16-0132. Epub 2016 Apr 11 2016
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| 5 | NOTCH4
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| AKT and 14-3-3 regulate Notch4 nuclear localization.
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| Ramakrishnan G, Davaakhuu G, Chung WC, Zhu H, Rana A, Filipovic A, Green AR, Atfi A, Pannuti A, Miele L, Tzivion G.
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| Sci Rep. Mar 5;5:8782. doi: 10.1038/srep0878 2015
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| 6 | IL1B, NOTCH1, NOTCH4
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| Activation of an endothelial Notch1-Jagged1 circuit induces VCAM1 expression, an effect amplified by interleukin-1β.
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| Verginelli F, Adesso L, Limon I, Alisi A, Gueguen M, Panera N, Giorda E, Raimondi L, Ciarapica R, Campese AF, Screpanti I, Stifani S, Kitajewski J, Miele L, Rota R, Locatelli F.
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| Oncotarget Dec 22;6(41):43216-29. doi: 10.18632/oncotarget.6456 2015
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| 7 | NOTCH4
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| Notch4 reveals a novel mechanism regulating Notch signal transduction.
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| James AC, Szot JO, Iyer K, Major JA, Pursglove SE, Chapman G, Dunwoodie SL.
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| Biochim Biophys Acta. Jul;1843(7):1272-84. doi: 10.1016/j.bbamcr.2014.03.015. Epub 2014 Mar 22 2014
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| 8 | NOTCH4
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| Notch4 is activated in endothelial and smooth muscle cells in human brain arteriovenous malformations.
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| ZhuGe Q, Wu Z, Huang L, Zhao B, Zhong M, Zheng W, GouRong C, Mao X, Xie L, Wang X, Jin K.
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| Version 2. J Cell Mol Med. Nov;17(11):1458-64. doi: 10.1111/jcmm.12115. Epub 2013 Nov 5 2013
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| 9 | NOTCH4
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| Genetic variants in the NOTCH4 gene influence the clinical features of migraine.
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| Rubino E, Fenoglio P, Gallone S, Govone F, Vacca A, De Martino P, Giobbe ML, Boschi S, Pinessi L, Gentile S, Rainero I.
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| J Headache Pain. Mar 26;14(1):28. doi: 10.1186/1129-2377-14-28 2013
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| 10 | NOTCH4, TP53
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| Trp53 regulates Notch 4 signaling through Mdm2.
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| Sun Y, Klauzinska M, Lake RJ, Lee JM, Santopietro S, Raafat A, Salomon D, Callahan R, Artavanis-Tsakonas S.
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| J Cell Sci 124(Pt 7):1067-76.
2011
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| 11 | ELOC, NOTCH4
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| Elongin C is a mediator of Notch4 activity in human renal tubule cells.
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| Cummins TD, Mendenhall MD, Lowry MN, Korte EA, Barati MT, Khundmiri SJ, Salyer SA, Klein JB, Powell DW.
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| Biochim Biophys Acta. Dec;1814(12):1748-57. doi: 10.1016/j.bbapap.2011.09.010. Epub 2011 Oct 5 2011
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| 12 | NOTCH4, TACC3
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| Transforming acidic coiled-coil protein-3 (Tacc3) acts as a negative regulator of Notch signaling through binding to CDC10/Ankyrin repeats.
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| Bargo S, Raafat A, McCurdy D, Amirjazil I, Shu Y, Traicoff J, Plant J, Vonderhaar BK, Callahan R.
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| Biochem Biophys Res Commun 400(4):606-12. Epub 2010 Sep 6.
2010
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| 13 | ANGPT2, EPHB3, JAG2, NETO2, NOTCH4
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| Identification of signaling systems in proliferating and involuting phase infantile hemangiomas by genome-wide transcriptional profiling.
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| Calicchio ML, Collins T, Kozakewich HP.
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| Am J Pathol 174(5):1638-49. Epub 2009 Apr 6.PMID: 19349369 2009
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| 14 | NOTCH4
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| Genetic association between Notch4 polymorphisms and Alzheimer's disease in the Japanese population.
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| Shibata N, Ohnuma T, Higashi S, Higashi M, Usui C, Ohkubo T, Watanabe T, Kawashima R, Kitajima A, Ueki A, Nagao M, Arai H.
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| J Gerontol A Biol Sci Med Sci 62(4):350-1. 2007
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| 15 | NOTCH1, NOTCH2, NOTCH3, NOTCH4
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| A role for notch signaling in human corneal epithelial cell differentiation and proliferation.
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| Ma A, Boulton M, Zhao B, Connon C, Cai J, Albon J.
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| Invest Ophthalmol Vis Sci 48(8):3576-85.PMID: 17652726 2007
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| 16 | NOTCH1,NOTCH2,NOTCH3,NOTCH4
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| Multiple functions of Notch signaling in self-renewing organs and cancer.
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| Wilson A, Radtke F.
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| FEBS Lett 580(12):2860-8. Epub 2006 Mar 20. 2006
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| 17 | NOTCH4
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| A review and re-evaluation of an association between the NOTCH4 locus and schizophrenia.
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| Wang Z, Wei J, Zhang X, Guo Y, Xu Q, Liu S, Shi J, Yu Y, Ju G, Li Y, Shen Y.
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| Am J Med Genet B Neuropsychiatr Genet 141(8):902-6. Review. 2006
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| 18 | NFKBIL1, TNXB, NOTCH4, MRPL48, PAAF1, UCP2, OPTN, CCDC3, LTB4R2
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| Whole genome association study of rheumatoid arthritis using 27 039 microsatellites.
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| Tamiya G, Shinya M, Imanishi T, Ikuta T, Makino S, Okamoto K, Furugaki K, Matsumoto T, Mano S, Ando S, Nozaki Y, Yukawa W, Nakashige R, Yamaguchi D, Ishibashi H, Yonekura M, Nakami Y, Takayama S, Endo T, Saruwatari T, Yagura M, Yoshikawa Y, Fujimoto K, Oka A, Chiku S, Linsen SE, Giphart MJ, Kulski JK, Fukazawa T, Hashimoto H, Kimura M, Hoshina Y, Suzuki Y, Hotta T, Mochida J, Minezaki T, Komai K, Shiozawa S, Taniguchi A, Yamanaka H, Kamatani N, Gojobori T, Bahram S, Inoko H.
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| Hum Mol Genet 14(16):2305-21. Epub 2005 Jul 6. 2005
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| 19 | NOTCH4
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| Molecular determinants of NOTCH4 transcription in vascular endothelium.
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| Wu J, Iwata F, Grass JA, Osborne CS, Elnitski L, Fraser P, Ohneda O, Yamamoto M, Bresnick EH.
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| Mol Cell Biol 25(4):1458-74. 2005
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| 20 | CADASIL, DLL1, Dll3, DLL4, JAG1, JAG2, NOTCH1, NOTCH2, NOTCH3, NOTCH4 , RBPJ, SCDO1
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| Notch signaling and inherited disease syndromes.
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| Gridley T.
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| Hum Mol Genet 12 Spec No 1:R9-13. Review. 2003
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| 21 | ALPCA1,ALPCA2,NOTCH1,NOTCH2,NOTCH3,NOTCH4
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| Notch signaling in development and disease.
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| Harper JA, Yuan JS, Tan JB, Visan I, Guidos CJ.
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| Clin Genet 64(6):461-72. 2003
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| 22 | NOTCH4
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| Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls.
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| Sklar P, Schwab SG, Williams NM, Daly M, Schaffner S, Maier W, Albus M, Trixler M, Eichhammer P, Lerer B, Hallmayer J, Norton N, Williams H, Zammit S, Cardno AG, Jones S, McCarthy G, Milanova V, Kirov G, O'Donovan MC, Lander ES, Owen MJ, Wildenauer DB.
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| Nat Genet 28(2):126-8. 2001
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| 23 | NOTCH4
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| Failure to confirm NOTCH4 association with schizophrenia in a large population-based sample from Scotland.
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| McGinnis RE, Fox H, Yates P, Cameron LA, Barnes MR, Gray IC, Spurr NK, Hurko O, St Clair D.
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| Nat Genet 28(2):128-9. 2001
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| 24 | NOTCH4
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| Identification of a novel NOTCH-4/INT-3 RNA species encoding an activated gene product in certain human tumor cell lines.
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| Imatani A, Callahan R.
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| Oncogene 19(2):223-31. 2000
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| 25 | LFNG, MFNG, NOTCH1, NOTCH2, NOTCH3, NOTCH4, NOTCH5, RFNG
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| Fringe is a glycosyltransferase that modifies Notch.
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| Moloney DJ, Panin VM, Johnston SH, Chen J, Shao L, Wilson R, Wang Y, Stanley P, Irvine KD, Haltiwanger RS, Vogt TF.
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| Nature 406(6794):369-75. 2000
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| 26 | LFNG, MFNG, NOTCH1, NOTCH2, NOTCH3, NOTCH4, NOTCH5, RFNG
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| Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.
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| Bruckner K, Perez L, Clausen H, Cohen S.
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| Nature 406(6794):411-5. 2000
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| 27 | NOTCH4
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| The NOTCH4 locus is associated with susceptibility to schizophrenia.
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| Wei J, Hemmings GP.
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| Nat Genet 25(4):376-7. 2000
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| 28 | NOTCH1, NOTCH4
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| Imbalanced expression of TAN-1 and human Notch4 in endometrial cancers.
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| Suzuki T, Aoki D, Susumu N, Udagawa Y, Nozawa S.
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| Int J Oncol 17(6):1131-9. 2000
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| 29 | NOTCH4, PSEN1
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| Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.
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| Ye Y, et al.
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| Nature 398(6727):525-9. 1999
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| 30 | NOTCH1, NOTCH2, NOTCH3, NOTCH4, PSEN1
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| Presenilin is required for activity and nuclear access of Notch in Drosophila.
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| Struhl G, et al.
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| Nature 398(6727):522-5. 1999
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| 31 | NOTCH1, NOTCH2, NOTCH3, NOTCH4, PSEN1
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| A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.
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| De Strooper B, et al.
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| Nature 398(6727):518-22. 1999
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| 32 | NOTCH4
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| Cloning, characterization, and the complete 56.8-kilobase DNA sequence of the human NOTCH4 gene.
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| Li L, et al.
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| Genomics 51 : 45-58. 1998
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| 33 | NOTCH4
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| Gene organization of human NOTCH4 and (CTG)n polymorphism in this human counterpart gene of mouse proto-oncogene Int3.
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| Sugaya K, Sasanuma S, Nohata J, Kimura T, Fukagawa T, Nakamura Y, Ando A, Inoko H, Ikemura T, Mita K.
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| Gene 189(2):235-44. 1997
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| 34 | NOTCH1,NOTCH4,PBX1,PBX2,PBX3,RXRA,RXRB,RXRG
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| Paralogy mapping : identification of a region in the human MHC triplicated onto human chromosomes 1 and 9 allows the prediction and isolation of novel PBX and NOTCH loci.
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| Katsanis N, et al.
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| Genomics 35 : 101-108. 1996
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| 35 | NOTCH4, PBX2, AGER
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| Three genes in the human MHC class III region near the junction with the class II : gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3.
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| Sugaya K, et al.
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| Genomics 23 : 408-419. 1994
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