Citations for
1NOS1
nNOS splice variants differentially regulate myofilament function but are dispensable for intracellular calcium and force transients in cardiac papillary muscles.
Kerrick WGL, Xu Y, Percival JM.
PLoS One 13(7):e0200834. doi: 10.1371/journal.pone.0200834. eCollection 2018. 2018
2NOS1
Maternal immune activation leads to increased nNOS immunoreactivity in the brain of postnatal day 2 rat offspring.
Zhang J, Jing Y, Zhang H, Bilkey DK, Liu P.
Synapse 72(1). doi: 10.1002/syn.22011. Epub 2017 Sep 27. 2018
3NOS1
Neuronal nitric oxide synthase mediates insulin- and oxidative stress-induced glucose uptake in skeletal muscle myotubes.
Kellogg DL 3rd, McCammon KM, Hinchee-Rodriguez KS, Adamo ML, Roman LJ.
Free Radic Biol Med 110:261-269. doi: 10.1016/j.freeradbiomed.2017.06.018. Epub 2017 Jun 27. 2017
4NOS1
Female-specific association of NOS1 genotype with white matter microstructure in ADHD patients and controls.
van Ewijk H, Bralten J, van Duin EDA, Hakobjan M, Buitelaar JK, Heslenfeld DJ, Hoekstra PJ, Hartman C, Hoogman M, Oosterlaan J, Franke B.
J Child Psychol Psychiatry 58(8):958-966. doi: 10.1111/jcpp.12742. Epub 2017 Jun 7. 2017
5NOS1
The Presence of the Neuronal Nitric Oxide Synthase Isoform in the Intervertebral Disk.
Castania V, Issy AC, Silveira JW, Ferreira FR, Titze-de-Almeida SS, Resende FF, Ferreira NR, Titze-de-Almeida R, Defino HL, Del Bel E.
Neurotox Res 31(1):148-161. doi: 10.1007/s12640-016-9676-7. Epub 2016 Oct 19. 2017
6NOS1
Neuronal NOS Induces Neuronal Differentiation Through a PKCα-Dependent GSK3β Inactivation Pathway in Hippocampal Neural Progenitor Cells.
Park SY, Kang MJ, Han JS.
Mol Neurobiol 54(7):5646-5656. doi: 10.1007/s12035-016-0110-1. Epub 2016 Sep 13. 2017
7NOS1
Neuronal Nitric Oxide Synthase Negatively Regulates Zinc-Induced Nigrostriatal Dopaminergic Neurodegeneration.
Singh BK, Kumar V, Chauhan AK, Dwivedi A, Singh S, Kumar A, Singh D, Patel DK, Ray RS, Jain SK, Singh C.
Mol Neurobiol 54(4):2685-2696. doi: 10.1007/s12035-016-9857-7. Epub 2016 Mar 19. 2017
8NOS1
Protein Inhibitor of NOS1 Plays a Central Role in the Regulation of NOS1 Activity in Human Dilated Hearts.
Roselló-Lletí E, Tarazón E, Ortega A, Gil-Cayuela C, Carnicer R, Lago F, González-Juanatey JR, Portolés M, Rivera M.
Sci Rep 6:30902. doi: 10.1038/srep30902. 2016
9NOS1
Human Ischemic Cardiomyopathy Shows Cardiac Nos1 Translocation and its Increased Levels are Related to Left Ventricular Performance.
Roselló-Lletí E, Carnicer R, Tarazón E, Ortega A, Gil-Cayuela C, Lago F, González-Juanatey JR, Portolés M, Rivera M.
Sci Rep 6:24060. doi: 10.1038/srep24060. 2016
10NOS1, SOX2
nNOS Translocates into the Nucleus and Interacts with Sox2 to Protect Neurons Against Early Excitotoxicity via Promotion of Shh Transcription.
Zhang D, Wang H, Liu H, Tao T, Wang N, Shen A.
Mol Neurobiol 53(9):6444-6458. doi: 10.1007/s12035-015-9545-z. Epub 2015 Nov 25. 2016
11NOS1, NOS2, NOS3
The dual role of iNOS in cancer.
Vannini F, Kashfi K, Nath N.
Redox Biol 6:334-43. doi: 10.1016/j.redox.2015.08.009. Epub 2015 Aug 24. Review. 2015
12NOS1
NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1.
Baig MS, Zaichick SV, Mao M, de Abreu AL, Bakhshi FR, Hart PC, Saqib U, Deng J, Chatterjee S, Block ML, Vogel SM, Malik AB, Consolaro ME, Christman JW, Minshall RD, Gantner BN, Bonini MG.
J Exp Med 212(10):1725-38. doi: 10.1084/jem.20140654. Epub 2015 Aug 31. 2015
13NOS1
NOS1 induces NADPH oxidases and impairs contraction kinetics in aged murine ventricular myocytes.
Villmow M, Klöckner U, Heymes C, Gekle M, Rueckschloss U.
Basic Res Cardiol 110(5):506. doi: 10.1007/s00395-015-0506-5. Epub 2015 Jul 15. 2015
14NOS1
Oxidative stress induces phosphorylation of neuronal NOS in cardiomyocytes through AMP-activated protein kinase (AMPK).
Kar R, Kellogg DL 3rd, Roman LJ.
Biochem Biophys Res Commun 459(3):393-7. doi: 10.1016/j.bbrc.2015.02.113. Epub 2015 Feb 27. 2015
15NOS1
Neuronal NOS localises to human airway cilia.
Jackson CL, Lucas JS, Walker WT, Owen H, Premadeva I, Lackie PM.
Nitric Oxide 44:3-7. doi: 10.1016/j.niox.2014.11.003. Epub 2014 Nov 6. 2015
16NOS1
Structures of human constitutive nitric oxide synthases.
Li H, Jamal J, Plaza C, Pineda SH, Chreifi G, Jing Q, Cinelli MA, Silverman RB, Poulos TL.
Acta Crystallogr D Biol Crystallogr 70(Pt 10):2667-74. doi: 10.1107/S1399004714017064. Epub 2014 Sep 27. 2014
17NOS1
Molecular architecture of mammalian nitric oxide synthases.
Campbell MG, Smith BC, Potter CS, Carragher B, Marletta MA.
Proc Natl Acad Sci U S A 111(35):E3614-23. doi: 10.1073/pnas.1413763111. Epub 2014 Aug 14. 2014
18NOS1, PRKD1
Protein kinase D interacts with neuronal nitric oxide synthase and phosphorylates the activatory residue serine 1412.
Sánchez-Ruiloba L, Aicart-Ramos C, García-Guerra L, Pose-Utrilla J, Rodríguez-Crespo I, Iglesias T.
PLoS One 9(4):e95191. doi: 10.1371/journal.pone.0095191. eCollection 2014. 2014
19NOS1, SNTA1
Nuclear recruitment of neuronal nitric-oxide synthase by α-syntrophin is crucial for the induction of mitochondrial biogenesis.
Aquilano K, Baldelli S, Ciriolo MR.
J Biol Chem 289(1):365-78. doi: 10.1074/jbc.M113.506733. Epub 2013 Nov 14. 2014
20NOS1
Neuronal nitric oxide synthase is phosphorylated in response to insulin stimulation in skeletal muscle.
Hinchee-Rodriguez K, Garg N, Venkatakrishnan P, Roman MG, Adamo ML, Masters BS, Roman LJ.
Biochem Biophys Res Commun 435(3):501-5. doi: 10.1016/j.bbrc.2013.05.020. Epub 2013 May 14. 2013
21NOS1
Renal collecting duct NOS1 maintains fluid-electrolyte homeostasis and blood pressure.
Hyndman KA, Boesen EI, Elmarakby AA, Brands MW, Huang P, Kohan DE, Pollock DM, Pollock JS.
Hypertension 62(1):91-8. doi: 10.1161/HYPERTENSIONAHA.113.01291. Epub 2013 Apr 22. 2013
22NOS1, TRPV1
Activation of calcium signaling through Trpv1 by nNOS and peroxynitrite as a key trigger of skeletal muscle hypertrophy.
Ito N, Ruegg UT, Kudo A, Miyagoe-Suzuki Y, Takeda S.
Nat Med 19(1):101-6. doi: 10.1038/nm.3019. Epub 2012 Dec 2. 2013
23NOS1
Ubiquitination of neuronal nitric-oxide synthase in the calmodulin-binding site triggers proteasomal degradation of the protein.
Clapp KM, Peng HM, Jenkins GJ, Ford MJ, Morishima Y, Lau M, Osawa Y.
J Biol Chem 287(51):42601-10. doi: 10.1074/jbc.M112.412494. Epub 2012 Oct 29. 2012
24CAST, NOS1
Age-related loss of nitric oxide synthase in skeletal muscle causes reductions in calpain S-nitrosylation that increase myofibril degradation and sarcopenia.
Samengo G, Avik A, Fedor B, Whittaker D, Myung KH, Wehling-Henricks M, Tidball JG.
Aging Cell 11(6):1036-45. doi: 10.1111/acel.12003. Epub 2012 Oct 4. 2012
25FMR1, NOS1
Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex.
Kwan KY, Lam MM, Johnson MB, Dube U, Shim S, Rašin MR, Sousa AM, Fertuzinhos S, Chen JG, Arellano JI, Chan DW, Pletikos M, Vasung L, Rowitch DH, Huang EJ, Schwartz ML, Willemsen R, Oostra BA, Rakic P, Heffer M, Kostović I, Judaš M, Sestan N.
Cell 149(4):899-911. doi: 10.1016/j.cell.2012.02.060. 2012
26LEPRB, NOS1
Leptin action through hypothalamic nitric oxide synthase-1-expressing neurons controls energy balance.
Leshan RL, Greenwald-Yarnell M, Patterson CM, Gonzalez IE, Myers MG Jr.
Nat Med 18(5):820-3. doi: 10.1038/nm.2724. 2012
27NOS1
Neuronal nitric oxide synthase regulates endothelial inflammation.
Chakrabarti S, Chan CK, Jiang Y, Davidge ST.
J Leukoc Biol 91(6):947-56. doi: 10.1189/jlb.1011513. Epub 2012 Mar 27. 2012
28NOS1
The beta-isoform of neuronal nitric oxide synthase (nNOS) lacking the PDZ domain is localized at the sarcolemma.
Baum O, Schläppi S, Huber-Abel FA, Weichert A, Hoppeler H, Zakrzewicz A.
FEBS Lett 585(20):3219-23. doi: 10.1016/j.febslet.2011.09.016. Epub 2011 Sep 19. 2011
29NOS1
Upregulation of neuronal nitric oxide synthase in the periphery promotes pain hypersensitivity after peripheral nerve injury.
Kim KH, Kim JI, Han JA, Choe MA, Ahn JH.
Neuroscience 190:367-78. doi: 10.1016/j.neuroscience.2011.05.064. Epub 2011 Jun 12. 2011
30NOS1
Bidirectional regulation of neurogenesis by neuronal nitric oxide synthase derived from neurons and neural stem cells.
Luo CX, Jin X, Cao CC, Zhu MM, Wang B, Chang L, Zhou QG, Wu HY, Zhu DY.
Stem Cells 28(11):2041-52. doi: 10.1002/stem.522. 2010
31NOS1
nNOS alpha and nNOS beta localization to aggresome-like inclusions is dependent on HSP90 activity.
Corso-Díaz X, Krukoff TL.
J Neurochem 114(3):864-72. doi: 10.1111/j.1471-4159.2010.06813.x. Epub 2010 May 14. 2010
32NOS1, NOS1AP
CAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the heart.
Chang KC, Barth AS, Sasano T, Kizana E, Kashiwakura Y, Zhang Y, Foster DB, Marbán E.
Proc Natl Acad Sci U S A 105(11):4477-82. Epub 2008 Mar 12. 2008
33NOS1
Neuronal nitric oxide synthase expression in glial tumors: correlation with malignancy and tumor proliferation.
Tanriover N, Ulu MO, Isler C, Durak H, Oz B, Uzan M, Akar Z.
Neurol Res 30(9):940-4. Epub 2008 Jul 30. 2008
34NOS1
Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo.
Seddon MD, Chowienczyk PJ, Brett SE, Casadei B, Shah AM.
Circulation 117(15):1991-6. Epub 2008 Apr 7. 2008
35NOS1
Nitric oxide synthase gene polymorphisms in children with primary nocturnal enuresis: a preliminary study.
Balat A, Alasehirli B, Oguzkan S, Gungor M.
Ren Fail 29(1):79-83. 2007
36NOS1
The untranslated region of exon 2 of the human neuronal nitric oxide synthase (NOS1) gene exerts regulatory activity.
Bros M, Boissel JP, Gšdtel-Armbrust U, Fšrstermann U.
Gene 405(1-2):36-46. Epub 2007 Sep 5. 2007
37NOS1, RPS6KA1
p90 RSK-1 associates with and inhibits neuronal nitric oxide synthase.
Song T, Sugimoto K, Ihara H, Mizutani A, Hatano N, Kume K, Kambe T, Yamaguchi F, Tokuda M, Watanabe Y.
Biochem J 401(2):391-8. 2007
38NOS1
Transcription of human neuronal nitric oxide synthase mRNAs derived from different first exons is partly controlled by exon 1-specific promoter sequences.
Bros M, Boissel JP, Godtel-Armbrust U, Forstermann U.
Genomics 87(4):463-73. Epub 2006 Jan 18. 2006
39NOS1, VAC14
Binding of Vac14 to neuronal nitric oxide synthase: Characterisation of a new internal PDZ-recognition motif.
Lemaire JF, McPherson PS.
FEBS Lett 580(30):6948-54. Epub 2006 Dec 4. 2006
40NOS1
Single-nucleotide promoter polymorphism alters transcription of neuronal nitric oxide synthase exon 1c in infantile hypertrophic pyloric stenosis.
Saur D, Vanderwinden JM, Seidler B, Schmid RM, De Laet MH, Allescher HD.
Proc Natl Acad Sci U S A 101(6):1662-7. Epub 2004 Feb 02. 2004
41NOS1
Variants of NOS1, NOS2, and NOS3 genes in asthmatics.
Gao PS, Kawada H, Kasamatsu T, Mao XQ, Roberts MH, Miyamoto Y, Yoshimura M, Saitoh Y, Yasue H, Nakao K, Adra CN, Kun JF, Moro-oka S, Inoko H, Ho LP, Shirakawa T, Hopkin JM.
Biochem Biophys Res Commun 267(3):761-3. 2000
42NOS1
Neuronal NOS: gene structure, mRNA diversity, and functional relevance.
Wang Y, et al.
Crit Rev Neurobiol 13(1):21-43. Review. 1999
43NOS1
CA repeat polymorphism of the neuronal nitric oxide synthase gene.
Takahashi Y, et al.
Hum Hered 47 : 58-59. 1997
44NOS1, NOS2, NOS2B, NOS2C, NOS3
Nitric oxide synthases: which, where, how, and why?
Michel T, Feron O.
J Clin Invest 100(9):2146-52. 1997
45NOS1
A novel, testis-specific mRNA transcript encoding an NH2-terminal truncated nitric-oxide synthase.
Wang Y, Goligorsky MS, Lin M, Wilcox JN, Marsden PA.
J Biol Chem 272(17):11392-401. 1997
46NOS1
Genetic evidence for the neuronal nitric oxide synthase gene (NOS1) as a susceptibility locus for infantile pyloric stenosis.
Chung E, et al.
Am J Hum Genet 58 : 363-370. 1996
47NOS1, ATXN2, ASCL1
Exclusion of the neuronal nitric oxide synthase gene and the human achaete-scute homologue I gene as candidate loci for spinal cerebellar ataxia 2.
Twells R, et al.
Am J Hum Genet 56 : 336-337. 1995
48NOS1, NOS2, NOS3
Nitric oxide synthases : roles, tolls, and controls.
Nathan C, et al.
Cell 78 : 915-918. 1994
49NOS1
Regional localization of the gene coding for human brain nitric oxide synthase (NOS1) to 12q24.2-24.31 by fluorescent in situ hybridization.
Xu W, et al.
Cytogenet Cell Genet 64 : 62-63. 1993
50NOS1, NOS3
Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene.
Marsden PA, et al.
J Biol Chem 268 : 17478-17488. 1993
51NOS1
Localization of brain nitric oxide synthase (NOS) to human chromosome 12.
Kishimoto J, et al.
Genomics 14 : 802-804. 1992