Citations for
1CSF2RA, MEGF6, NOD2
Copy number variation exploration of multiple genes in SAPHO syndrome.
Guo C, Tian X, Hand F, Liu L, Gao J, Ma X.
J Rheumatol Rheumatol. 2019 Oct 15. pii: jrheum.181393. doi: 10.3899/jrheum.181393. [Epub ahead of print] 2019
2LACC1, NOD2, PLCG2
Using genes to triangulate the pathophysiology of granulomatous autoinflammatory disease: NOD2, PLCG2 and LACC1.
Szymanski AM, Ombrello MJ.
Int Immunol 30(5):205-213. doi: 10.1093/intimm/dxy021. 2018
3NOD2, TWIST1, TWIST2
Twist1 and Twist2 Contribute to Cytokine Downregulation following Chronic NOD2 Stimulation of Human Macrophages through the Coordinated Regulation of Transcriptional Repressors and Activators.
Zheng S, Hedl M, Abraham C.
J Immunol 195(1):217-26. doi: 10.4049/jimmunol.1402808. Epub 2015 May 27. 2015
4ATG16L1, NOD2
Evidence of expression variation and allelic imbalance in Crohn's disease susceptibility genes NOD2 and ATG16L1 in human dendritic cells.
Hu J, Peter I.
Gene 527(2):496-502. doi: 10.1016/j.gene.2013.06.066. Epub 2013 Jul 10. 2013
5BIRC2, ITCH, NOD2
A discrete ubiquitin-mediated network regulates the strength of NOD2 signaling.
Tigno-Aranjuez JT, Bai X, Abbott DW.
Mol Cell Biol 33(1):146-58. doi: 10.1128/MCB.01049-12. Epub 2012 Oct 29. 2013
6ATG16L1, NOD1, NOD2, RIPK2
Ubiquitin regulates caspase recruitment domain-mediated signaling by nucleotide-binding oligomerization domain-containing proteins NOD1 and NOD2.
Ver Heul AM, Fowler CA, Ramaswamy S, Piper RC.
J Biol Chem 288(10):6890-902. doi: 10.1074/jbc.M112.413781. Epub 2013 Jan 8. 2013
7NOD2, PELI3, RIPK2
Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis.
Yang S, Wang B, Humphries F, Jackson R, Healy ME, Bergin R, Aviello G, Hall B, McNamara D, Darby T, Quinlan A, Shanahan F, Melgar S, Fallon PG, Moynagh PN.
Nat Immunol 14(9):927-36. doi: 10.1038/ni.2669. Epub 2013 Jul 28. 2013
8ATF3, NFKB1, NOD2
NF-κB1 inhibits NOD2-induced cytokine secretion through ATF3-dependent mechanisms.
Zheng S, Abraham C.
Mol Cell Biol 33(24):4857-71. doi: 10.1128/MCB.00797-13. Epub 2013 Oct 7. 2013
9NOD2, TRPC6
Novel role of NOD2 in mediating Ca2+ signaling: evidence from NOD2-regulated podocyte TRPC6 channels in hyperhomocysteinemia.
Han H, Wang Y, Li X, Wang PA, Wei X, Liang W, Ding G, Yu X, Bao C, Zhang Y, Wang Z, Yi F.
Hypertension 62(3):506-11. doi: 10.1161/HYPERTENSIONAHA.113.01638. Epub 2013 Jul 15. 2013
10ANKRD17, NOD2
A role for the Ankyrin repeat containing protein Ankrd17 in Nod1- and Nod2-mediated inflammatory responses
Menning M, Kufer TA.
FEBS Lett. Jul 11;587(14):2137-42. doi: 10.1016/j.febslet.2013.05.037 2013
11HEATR3, NOD2
Extended haplotype association study in Crohn's disease identifies a novel, Ashkenazi Jewish-specific missense mutation in the NF-κB pathway gene, HEATR3
Zhang W, Hui KY, Gusev A, Warner N, Ng SM, Ferguson J, Choi M, Burberry A, Abraham C, Mayer L, Desnick RJ, Cardinale CJ, Hakonarson H, Waterman M, Chowers Y, Karban A, Brant SR, Silverberg MS, Gregersen PK, Katz S, Lifton RP, Zhao H, Nuñez G, Pe'er I, Peter I, Cho JH
Genes Immun. Jul-Aug;14(5):310-6. doi: 10.1038/gene.2013.19. Epub 2013 Apr 25. 2013
12NOD2, VIM
The intermediate filament protein, vimentin, is a regulator of NOD2 activity.
Stevens C, Henderson P, Nimmo ER, Soares DC, Dogan B, Simpson KW, Barrett JC; International Inflammatory Bowel Disease Genetics Consortium, Wilson DC, Satsangi J.
Gut ut. 2012 Jul 10. [Epub ahead of print] 2012
13NOD2, RIPK2
A dual role for receptor-interacting protein kinase 2 (RIP2) kinase activity in nucleotide-binding oligomerization domain 2 (NOD2)-dependent autophagy.
Homer CR, Kabi A, Marina-García N, Sreekumar A, Nesvizhskii AI, Nickerson KP, Chinnaiyan AM, Nuñez G, McDonald C.
J Biol Chem 287(30):25565-76. doi: 10.1074/jbc.M111.326835. Epub 2012 Jun 4. 2012
14NOD2, TRAF4
IκB kinase α phosphorylation of TRAF4 downregulates innate immune signaling.
Marinis JM, Hutti JE, Homer CR, Cobb BA, Cantley LC, McDonald C, Abbott DW.
Mol Cell Biol 32(13):2479-89. doi: 10.1128/MCB.00106-12. Epub 2012 Apr 30. 2012
15NOD2, TRIM27
TRIM27 negatively regulates NOD2 by ubiquitination and proteasomal degradation.
Zurek B, Schoultz I, Neerincx A, Napolitano LM, Birkner K, Bennek E, Sellge G, Lerm M, Meroni G, Söderholm JD, Kufer TA.
PLoS One 7(7):e41255. doi: 10.1371/journal.pone.0041255. Epub 2012 Jul 19. 2012
16MAPKBP1, NOD2
The c-Jun N-terminal kinase (JNK)-binding protein (JNKBP1) acts as a negative regulator of NOD2 protein signaling by inhibiting its oligomerization process.
Lecat A, Di Valentin E, Somja J, Jourdan S, Fillet M, Kufer TA, Habraken Y, Sadzot C, Louis E, Delvenne P, Piette J, Legrand-Poels S.
J Biol Chem 287(35):29213-26. doi: 10.1074/jbc.M112.355545. Epub 2012 Jun 14. 2012
17ERBIN, FRMPD2, NOD2
RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition
Lipinski S, Grabe N, Jacobs G, Billmann-Born S, Till A, Häsler R, Aden K, Paulsen M, Arlt A, Kraemer L, Hagemann N, Erdmann KS, Schreiber S, Rosenstiel P.
Proc Natl Acad Sci U S A. Dec 26;109(52):21426-31. doi: 10.1073/pnas.1209673109. Epub 2012 Dec 3. 2012
18NOD2, TRAF4
A novel motif in the Crohn's disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responses.
Marinis JM, Homer CR, McDonald C, Abbott DW.
J Biol Chem 286(3):1938-50. Epub 2010 Nov 19. 2011
19ATG16L1, NOD2
ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis.
Homer CR, Richmond AL, Rebert NA, Achkar JP, McDonald C.
Gastroenterology 139(5):1630-41, 1641.e1-2. doi: 10.1053/j.gastro.2010.07.006. Epub 2010 Jul 14. 2010
20ATG16L1, NOD2
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry.
Travassos LH, Carneiro LA, Ramjeet M, Hussey S, Kim YG, Magalhães JG, Yuan L, Soares F, Chea E, Le Bourhis L, Boneca IG, Allaoui A, Jones NL, Nuñez G, Girardin SE, Philpott DJ.
Nat Immunol 11(1):55-62. doi: 10.1038/ni.1823. Epub 2009 Nov 8. 2010
21NOD1, NOD2
Hepatocytes express functional NOD1 and NOD2 receptors: a role for NOD1 in hepatocyte CC and CXC chemokine production.
Scott MJ, Chen C, Sun Q, Billiar TR.
J Hepatol 53(4):693-701. doi: 10.1016/j.jhep.2010.04.026. Epub 2010 Jun 16. 2010
22NOD1, NOD2
Nod1 and nod2 are expressed in human and murine renal tubular epithelial cells and participate in renal ischemia reperfusion injury.
Shigeoka AA, Kambo A, Mathison JC, King AJ, Hall WF, da Silva Correia J, Ulevitch RJ, McKay DB.
J Immunol 184(5):2297-304. doi: 10.4049/jimmunol.0903065. Epub 2010 Feb 1. 2010
23CASP8, NOD2
Caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling.
von Kampen O, Lipinski S, Till A, Martin SJ, Nietfeld W, Lehrach H, Schreiber S, Rosenstiel P.
J Biol Chem 285(26):19921-6. doi: 10.1074/jbc.M110.127480. Epub 2010 Apr 12. 2010
24CARD8, NOD2
Caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling.
von Kampen O, Lipinski S, Till A, Martin SJ, Nietfeld W, Lehrach H, Schreiber S, Rosenstiel P.
J Biol Chem 285(26):19921-6. doi: 10.1074/jbc.M110.127480. Epub 2010 Apr 12. 2010
25NOD1, NOD2, RIPK2, XIAP
XIAP mediates NOD signaling via interaction with RIP2.
Krieg A, Correa RG, Garrison JB, Le Negrate G, Welsh K, Huang Z, Knoefel WT, Reed JC.
Proc Natl Acad Sci U S A 106(34):14524-9. Epub 2009 Aug 10.PMID: 19667203 2009
26NOD2
Genotyping for NOD2 genetic variants and crohn disease: a metaanalysis.
Yazdanyar S, Weischer M, Nordestgaard BG.
Clin Chem 55(11):1950-7. Epub 2009 Aug 27.PMID: 19713276 2009
27NOD2
Activation of innate immune antiviral responses by Nod2.
Sabbah A, Chang TH, Harnack R, Frohlich V, Tominaga K, Dube PH, Xiang Y, Bose S.
Nat Immunol 10(10):1073-80. Epub 2009 Aug 23.PMID: 19701189 2009
28NOD2, RIPK2
Nod2 is required for the regulation of commensal microbiota in the intestine.
Petnicki-Ocwieja T, Hrncir T, Liu YJ, Biswas A, Hudcovic T, Tlaskalova-Hogenova H, Kobayashi KS.
Proc Natl Acad Sci U S A 106(37):15813-8. Epub 2009 Sep 1.PMID: 19805227 2009
29CDAN2, LPRS4, NOD2, SEC23A, SEC23B
Genomewide association study of leprosy.
Zhang FR, Huang W, Chen SM, Sun LD, Liu H, Li Y, Cui Y, Yan XX, Yang HT, Yang RD, Chu TS, Zhang C, Zhang L, Han JW, Yu GQ, Quan C, Yu YX, Zhang Z, Shi BQ, Zhang LH, Cheng H, Wang CY, Lin Y, Zheng HF, Fu XA, Zuo XB, Wang Q, Long H, Sun YP, Cheng YL, Tian HQ, Zhou FS, Liu HX, Lu WS, He SM, Du WL, Shen M, Jin QY, Wang Y, Low HQ, Erwin T, Yang NH, Li JY, Zhao X, Jiao YL, Mao LG, Yin G, Jiang ZX, Wang XD, Yu JP, Hu ZH, Gong CH, Liu YQ, Liu RY, Wang DM, Wei D, Liu JX, Cao WK, Cao HZ, Li YP, Yan WG, Wei SY, Wang KJ, Hibberd ML, Yang S, Zhang XJ, Liu JJ.
N Engl J Med 361(27):2609-18. Epub 2009 Dec 16. 2009
30NOD2, OAS2, RNASEL
Nucleotide oligomerization domain-2 interacts with 2'-5'-oligoadenylate synthetase type 2 and enhances RNase-L function in THP-1 cells.
Dugan JW, Albor A, David L, Fowlkes J, Blackledge MT, Martin TM, Planck SR, Rosenzweig HL, Rosenbaum JT, Davey MP.
Mol Immunol 47(2-3):560-6. Epub 2009 Oct 23.PMID: 19853919 2009
31CLEC16A, NOD2
Specific association of a CLEC16A/KIAA0350 polymorphism with NOD2/CARD15(-) Crohn's disease patients.
Márquez A, Varadé J, Robledo G, Martínez A, Mendoza JL, Taxonera C, Fernández-Arquero M, Díaz-Rubio M, Gómez-García M, López-Nevot MA, de la Concha EG, Martín J, Urcelay E.
Eur J Hum Genet 17(10):1304-8. Epub 2009 Apr 1.PMID: 19337309 2009
32ITCH, NOD2, RIPK2
ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways.
Tao M, Scacheri PC, Marinis JM, Harhaj EW, Matesic LE, Abbott DW.
Curr Biol 19(15):1255-63. Epub 2009 Jul 9.PMID: 19592251 2009
33NOD1, NOD2, RIPK2
The kinase activity of Rip2 determines its stability and consequently Nod1- and Nod2-mediated immune responses.
Nembrini C, Kisielow J, Shamshiev AT, Tortola L, Coyle AJ, Kopf M, Marsland BJ.
J Biol Chem 284(29):19183-8. doi: 10.1074/jbc.M109.006353. Epub 2009 May 27. 2009
34NOD1, NOD2
Regulation of Nod1 and Nod2 in first trimester trophoblast cells.
Mulla MJ, Yu AG, Cardenas I, Guller S, Panda B, Abrahams VM.
Am J Reprod Immunol 61(4):294-302. doi: 10.1111/j.1600-0897.2009.00694.x. 2009
35NOD1, NOD2
Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis.
Joosten LA, Heinhuis B, Abdollahi-Roodsaz S, Ferwerda G, Lebourhis L, Philpott DJ, Nahori MA, Popa C, Morre SA, van der Meer JW, Girardin SE, Netea MG, van den Berg WB.
Proc Natl Acad Sci U S A 105(26):9017-22. Epub 2008 Jun 23. 2008
36NOD2
Mutation screening of the CARD15 gene in sarcoidosis.
Akahoshi M, Ishihara M, Namba K, Kitaichi N, Ando Y, Takenaka S, Ishida T, Ohno S, Mizuki N, Nakashima H, Shirakawa T.
Tissue Antigens 71(6):564-7. Epub 2008 Apr 2.PMID: 18384487 2008
37FPR2, NOD2
Cooperation between NOD2 and Toll-like receptor 2 ligands in the up-regulation of mouse mFPR2, a G-protein-coupled Abeta42 peptide receptor, in microglial cells.
Chen K, Zhang L, Huang J, Gong W, Dunlop NM, Wang JM.
J Leukoc Biol 83(6):1467-75. doi: 10.1189/jlb.0907607. Epub 2008 Feb 25. 2008
38NOD2
Estimating the odds ratios of Crohn disease for the main CARD15/NOD2 mutations using a conditional maximum likelihood method in pedigrees collected via affected family members.
Pascoe L, Zouali H, Sahbatou M, Hugot JP.
Eur J Hum Genet 15(8):864-71. Epub 2007 Apr 25. 2007
39NOD2
Identification, evolution, and association study of a novel promoter and first exon of the human NOD2 (CARD15) gene.
King K, Bagnall R, Fisher SA, Sheikh F, Cuthbert A, Tan S, Mundy NI, Rosenstiel P, Schreiber S, Mathew CG, Roberts RG.
Genomics 90(4):493-501. Epub 2007 Aug 24. 2007
40CHIT1, NOD2
TLR- and NOD2-dependent regulation of human phagocyte-specific chitotriosidase.
van Eijk M, Scheij SS, van Roomen CP, Speijer D, Boot RG, Aerts JM.
FEBS Lett 581(28):5389-95. Epub 2007 Oct 30. 2007
41NOD2, RIPK2
The NOD2-RICK complex signals from the plasma membrane.
Lécine P, Esmiol S, Métais JY, Nicoletti C, Nourry C, McDonald C, Nunez G, Hugot JP, Borg JP, Ollendorff V.
J Biol Chem 282(20):15197-207. Epub 2007 Mar 13.PMID: 17355968 2007
42BLAU, NOD2
A sporadic case of early-onset sarcoidosis resembling Blau syndrome due to the recurrent R334W missense mutation on the NOD2 gene.
Coto-Segura P, Mallo-Garcia S, Costa-Romero M, Arostegui JI, Yague J, Ramos-Polo E, Santos-Juanes J.
Br J Dermatol 157(6):1257-9. Epub 2007 Oct 4.PMID: 17916199 2007
43IBD1, NOD2
Mutations in CARD15 and smoking confer susceptibility to Crohn's disease in the Danish population.
Ernst A, Jacobsen B, Østergaard M, Okkels H, Andersen V, Dagiliene E, Pedersen IS, Thorsgaard N, Drewes AM, Krarup HB.
Scand J Gastroenterol 42(12):1445-51. 2007
44NOD2, DLG5
Extreme heterogeneity in CARD15 and DLG5 Crohn disease-associated polymorphisms between German and Norwegian populations.
Medici V, Mascheretti S, Croucher PJ, Stoll M, Hampe J, Grebe J, Sturniolo GC, Solberg C, Jahnsen J, Moum B, Schreiber S, Vatn MH.
Eur J Hum Genet 14(4):459-68. 2006
45NOD2
Molecular stratification of Crohn's disease by chemokine receptors: fractalkine receptor polymorphisms define a fibrostenosing ileal subgroup.
Binion DG, Kugathasan S, Dwinell MB.
Am J Gastroenterol 101(1):107-9. 2006
46NOD2, RIPK2
A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways.
Rosenstiel P, Huse K, Till A, Hampe J, Hellmig S, Sina C, Billmann S, von Kampen O, Waetzig GH, Platzer M, Seegert D, Schreiber S.
Proc Natl Acad Sci U S A 103(9):3280-5. Epub 2006 Feb 21.PMID: 16492792 2006
47BLAU, NOD2
A new CARD15 mutation in Blau syndrome.
van Duist MM, Albrecht M, Podswiadek M, Giachino D, Lengauer T, Punzi L, De Marchi M.
Eur J Hum Genet 13(6):742-7. 2005
48NOD2, IBD1
Genetics of Crohn disease, an archetypal inflammatory barrier disease.
Schreiber S, Rosenstiel P, Albrecht M, Hampe J, Krawczak M.
Nat Rev Genet 6(5):376-88. Review. 2005
49NOD2, BLAU
Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndrome.
Kanazawa N, Okafuji I, Kambe N, Nishikomori R, Nakata-Hizume M, Nagai S, Fuji A, Yuasa T, Manki A, Sakurai Y, Nakajima M, Kobayashi H, Fujiwara I, Tsutsumi H, Utani A, Nishigori C, Heike T, Nakahata T, Miyachi Y.
Blood 105(3):1195-7. Epub 2004 Sep 30. 2005
50NOD2, DLG5
Genetic variation in DLG5 is associated with inflammatory bowel disease.
Stoll M, Corneliussen B, Costello CM, Waetzig GH, Mellgard B, Koch WA, Rosenstiel P, Albrecht M, Croucher PJ, Seegert D, Nikolaus S, Hampe J, Lengauer T, Pierrou S, Foelsch UR, Mathew CG, Lagerstrom-Fermer M, Schreiber S.
Nat Genet 36(5):476-80. Epub 2004 Apr 11. 2004
51NOD2
CARD15/NOD2 Risk Alleles in the Development of Crohn's Disease in the Australian Population.
Cavanaugh JA, Adams KE, Quak EJ, Bryce ME, O'Callaghan NJ, Rodgers HJ, Magarry GR, Butler WJ, Eaden JA, Roberts-Thomson IC, Pavli P, Wilson SR, Callen DF.
Ann Hum Genet 67(Pt 1):35-41. 2003
52NOD2
Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations.
Croucher PJ, Mascheretti S, Hampe J, Huse K, Frenzel H, Stoll M, Lu T, Nikolaus S, Yang SK, Krawczak M, Kim WH, Schreiber S.
Eur J Hum Genet 11(1):6-16. 2003
53NOD2, IBD1, IBD5
Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease.
Mirza MM, Fisher SA, King K, Cuthbert AP, Hampe J, Sanderson J, Mansfield J, Donaldson P, Macpherson AJ, Forbes A, Schreiber S, Lewis CM, Mathew CG.
Am J Hum Genet 72(4):1018-22. Epub 2003 Mar 03. 2003
54NOD2
CARD15: a pleiotropic autoimmune gene that confers susceptibility to psoriatic arthritis.
Rahman P, Bartlett S, Siannis F, Pellett FJ, Farewell VT, Peddle L, Schentag CT, Alderdice CA, Hamilton S, Khraishi M, Tobin Y, Hefferton D, Gladman DD.
Am J Hum Genet 73(3):677-81. Epub 2003 Jul 23. 2003
55NOD2
Stratification by CARD15 variant genotype in a genome-wide search for inflammatory bowel disease susceptibility loci.
Shaw SH, Hampe J, White R, Mathew CG, Curran ME, Schreiber S.
Hum Genet 113(6):514-21. Epub 2003 Sep 13. 2003
56NOD2
CARD15 genotyping in inflammatory bowel disease patients by multiplex pyrosequencing.
Palmieri O, Toth S, Ferraris A, Andriulli A, Latiano A, Annese V, Dallapiccola B, Vecchi M, Devoto M, Surrey S, Fortina P.
Clin Chem 49(10):1675-9. No abstract available. 2003
57NLRC3, NLRC5, NLRP10, NLRP14, NLRP2P, NLRP3P, NLRP9P, NLRX1, NOD1, NOD2
NODs: intracellular proteins involved in inflammation and apoptosis.
Inohara N, Nunez G.
Nat Rev Immunol 3(5):371-82. Review. 2003
58CD14, NOD2
Interaction of polymorphisms in the CARD15 and CD14 genes in patients with Crohn disease.
Klein W, Tromm A, Griga T, Folwaczny C, Hocke M, Eitner K, Marx M, Duerig N, Epplen JT.
Scand J Gastroenterol 38(8):834-6. 2003
59NOD2, NLRP3
Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2.
Albrecht M, Domingues FS, Schreiber S, Lengauer T.
FEBS Lett 554(3):520-8. 2003
60BLAU, NOD2, IBD1
CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease.
Lesage S, Zouali H, Cezard JP, Colombel JF, Belaiche J, Almer S, Tysk C, O'Morain C, Gassull M, Binder V, Finkel Y, Modigliani R, Gower-Rousseau C, Macry J, Merlin F, Chamaillard M, Jannot AS, Thomas G, Hugot JP.
Am J Hum Genet 70(4):845-57. 2002
61NOD2
Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study.
Hampe J, Grebe J, Nikolaus S, Solberg C, Croucher PJ, Mascheretti S, Jahnsen J, Moum B, Klump B, Krawczak M, Mirza MM, Foelsch UR, Vatn M, Schreiber S.
Lancet 359(9318):1661-5. 2002
62NOD2
The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease.
Cuthbert AP, Fisher SA, Mirza MM, King K, Hampe J, Croucher PJ, Mascheretti S, Sanderson J, Forbes A, Mansfield J, Schreiber S, Lewis CM, Mathew CG.
Gastroenterology 122(4):867-74. 2002
63NOD2
CARD15 gene and the classification of Crohn's disease.
Murillo L, Crusius JB, van Bodegraven AA, Alizadeh BZ, Pena AS.
Immunogenetics 54(1):59-61. Epub 2002 Mar 02. 2002
64NOD2
Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease.
Abreu MT, Taylor KD, Lin YC, Hang T, Gaiennie J, Landers CJ, Vasiliauskas EA, Kam LY, Rojany M, Papadakis KA, Rotter JI, Targan SR, Yang H.
Gastroenterology 123(3):679-88. 2002
65NOD1, NOD2
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB.
Ogura Y, Inohara N, Benito A, Chen FF, Yamaoka S, Nunez G.
J Biol Chem 276(7):4812-8. 2001
66IBD1, NOD2
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations.
Hampe J, Cuthbert A, Croucher PJ, Mirza MM, Mascheretti S, Fisher S, Frenzel H, King K, Hasselmeyer A, MacPherson AJ, Bridger S, van Deventer S, Forbes A, Nikolaus S, Lennard-Jones JE, Foelsch UR, Krawczak M, Lewis C, Schreiber S, Mathew CG.
Lancet 357(9272):1925-8. 2001
67IBD1, NOD2
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease.
Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, Almer S, Tysk C, O'Morain CA, Gassull M, Binder V, Finkel Y, Cortot A, Modigliani R, Laurent-Puig P, Gower-Rousseau C, Macry J, Colombel JF, Sahbatou M, Thomas G.
Nature 411(6837):599-603. 2001
68IBD1, NOD2
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease.
Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, Britton H, Moran T, Karaliuskas R, Duerr RH, Achkar JP, Brant SR, Bayless TM, Kirschner BS, Hanauer SB, Nunez G, Cho JH.
Nature 411(6837):603-6. 2001
69BLAU, NOD2
CARD15 mutations in Blau syndrome.
Miceli-Richard C, Lesage S, Rybojad M, Prieur AM, Manouvrier-Hanu S, Hafner R, Chamaillard M, Zouali H, Thomas G, Hugot JP.
Nat Genet 29(1):19-20. 2001
70BCL10, CARD10, CARD11, NLRC4, CARD14, NOD1, NOD2, CARD9, RIPK2
Caspase recruitment domain (CARD)-dependent cytoplasmic filaments mediate bcl10-induced NF-kappaB activation.
Guiet C, Vito P.
J Cell Biol 148(6):1131-40. 2000