Citations for
1NNT
Nicotinamide nucleotide transhydrogenase (Nnt) links the substrate requirement in brain mitochondria for hydrogen peroxide removal to the thioredoxin/peroxiredoxin (Trx/Prx) system.
Lopert P, Patel M.
J Biol Chem 289(22):15611-20. doi: 10.1074/jbc.M113.533653. Epub 2014 Apr 10. 2014
2NNT
A spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL/6J mice results in mitochondrial redox abnormalities.
Ronchi JA, Figueira TR, Ravagnani FG, Oliveira HC, Vercesi AE, Castilho RF.
Free Radic Biol Med 63:446-56. doi: 10.1016/j.freeradbiomed.2013.05.049. Epub 2013 Jun 7. 2013
3NNT
Cofactor balance by nicotinamide nucleotide transhydrogenase (NNT) coordinates reductive carboxylation and glucose catabolism in the tricarboxylic acid (TCA) cycle.
Gameiro PA, Laviolette LA, Kelleher JK, Iliopoulos O, Stephanopoulos G.
J Biol Chem 288(18):12967-77. doi: 10.1074/jbc.M112.396796. Epub 2013 Mar 15. 2013
4HERPUD1, NNT
A novel mechanism regulating insulin secretion involving Herpud1 in mice.
Wong N, Morahan G, Stathopoulos M, Proietto J, Andrikopoulos S.
Diabetologia 56(7):1569-76. doi: 10.1007/s00125-013-2908-y. Epub 2013 Apr 26. 2013
5FGCD4, NNT
Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency.
Meimaridou E, Kowalczyk J, Guasti L, Hughes CR, Wagner F, Frommolt P, Nürnberg P, Mann NP, Banerjee R, Saka HN, Chapple JP, King PJ, Clark AJ, Metherell LA.
Nat Genet 44(7):740-2. doi: 10.1038/ng.2299. 2012
6NNT
Nicotinamide nucleotide transhydrogenase (NNT) acts as a novel modulator of macrophage inflammatory responses.
Ripoll VM, Meadows NA, Bangert M, Lee AW, Kadioglu A, Cox RD.
FASEB J 26(8):3550-62. doi: 10.1096/fj.11-199935. Epub 2012 May 16. 2012
7NNT
Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.
Parker N, Vidal-Puig AJ, Azzu V, Brand MD.
Biochim Biophys Acta 1787(12):1451-7. Epub 2009 Jun 17.PMID: 19539600 2009
8NNT
Insulin secretion from beta-cells is affected by deletion of nicotinamide nucleotide transhydrogenase.
Shimomura K, Galvanovskis J, Goldsworthy M, Hugill A, Kaizak S, Lee A, Meadows N, Quwailid MM, Rydström J, Teboul L, Ashcroft F, Cox RD.
Methods Enzymol 457:451-80. doi: 10.1016/S0076-6879(09)05025-3. 2009
9BASP1, BRD9, DROSHA, NDUFS6, NNT, OSMR, PAIP1, PAPD7, RAD1, SDHA, SKP2, TARS
Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha.
Scotto L, Narayan G, Nandula SV, Subramaniyam S, Kaufmann AM, Wright JD, Pothuri B, Mansukhani M, Schneider A, Arias-Pulido H, Murty VV.
Mol Cancer 7:58. 2008
10NNT
ncreased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes.
Aston-Mourney K, Wong N, Kebede M, Zraika S, Balmer L, McMahon JM, Fam BC, Favaloro J, Proietto J, Morahan G, Andrikopoulos S.
Diabetologia 50(12):2476-85. Epub 2007 Oct 6.PMID: 17922105 2007
11ABHD10, AP1AR, APH1B, C12orf25, C12orf29, C15orf44, C16orf48, C16orf53, C19orf47, C20orf132, C3orf23, C4orf18, C4orf27, C4orf40, C6orf89, CNST, CYB5R4, DEPDC7, DEPTOR, EFCAB7, FAM172A, FAM192A, GPR155, KIAA1826, LMAN2L, LYSMD3, MAP11, MIG3, MPC2, NNT, RAB1A, SCN3B, SERP1, SNN, SPRTN, TMPRSS11B
The LIFEdb database in 2006.
Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S.
Nucleic Acids Res 34(Database issue):D415-8. 2006
12NNT
Nicotinamide nucleotide transhydrogenase: a link between insulin secretion, glucose metabolism and oxidative stress.
Freeman H, Shimomura K, Cox RD, Ashcroft FM.
Biochem Soc Trans 34(Pt 5):806-10. 2006
13NNT
Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion.
Freeman H, Shimomura K, Horner E, Cox RD, Ashcroft FM.
Cell Metab 3(1):35-45. 2006
14NNT
Expression of proton-pumping nicotinamide nucleotide transhydrogenase in mouse, human brain and C elegans.
Arkblad EL, Egorov M, Shakhparonov M, Romanova L, Polzikov M, Rydstršm J.
Comp Biochem Physiol B Biochem Mol Biol 133(1):13-21. 2002
15NNT
Cloning and deduced amino acid sequence of human nicotinamide nucleotide transhydrogenase.
Zieger B, et al.
DNA Seq 7(6):369-73 1997
16NNT
Mapping of the rat and mouse nicotinamide nucleotide transhydrogenase gene.
Arkblad EL, et al.
Mamm Genome 8(9):703. No abstract available 1997
17NNT
The cDNA sequence of proton-pumping nicotinamide nucleotide transhydrogenase from man and mouse.
Arkblad EL, et al.
Biochim Biophys Acta 1273(3):203-5 1996