1 | IKBKG, NMRAL1, USP7
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| HSCARG downregulates NF-κB signaling by interacting with USP7 and inhibiting NEMO ubiquitination.
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| Li T, Guan J, Li S, Zhang X, Zheng X.
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| Cell Death Dis 5:e1229. doi: 10.1038/cddis.2014.197.
2014
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2 | NMRAL1, OTUB1, TRAF3
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| HSCARG negatively regulates the cellular antiviral RIG-I like receptor signaling pathway by inhibiting TRAF3 ubiquitination via recruiting OTUB1.
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| Peng Y, Xu R, Zheng X.
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| PLoS Pathog 10(4):e1004041. doi: 10.1371/journal.ppat.1004041. eCollection 2014 Apr.
2014
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3 | NMRAL1, USP7
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| HSCARG, a novel regulator of H2A ubiquitination by downregulating PRC1 ubiquitin E3 ligase activity, is essential for cell proliferation.
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| Hu B, Li S, Zhang X, Zheng X.
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| Nucleic Acids Res 42(9):5582-93. doi: 10.1093/nar/gku230. Epub 2014 Apr 7.
2014
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4 | NCF1, NMRAL1
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| HSCARG, a novel regulator of H2A ubiquitination by downregulating PRC1 ubiquitin E3 ligase activity, is essential for cell proliferation.
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| Hu B, Li S, Zhang X, Zheng X.
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| Nucleic Acids Res 42(9):5582-93. doi: 10.1093/nar/gku230. Epub 2014 Apr 7.
2014
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5 | NMRAL1
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| A CRM1-dependent nuclear export signal controls nucleocytoplasmic translocation of HSCARG, which regulates NF-κB activity.
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| Zhang M, Hu B, Li T, Peng Y, Guan J, Lai S, Zheng X.
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| Traffic 13(6):790-9. doi: 10.1111/j.1600-0854.2012.01346.x. Epub 2012 Mar 14.
2012
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6 | NMRAL1
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| HSCARG inhibits activation of NF-kappaB by interacting with IkappaB kinase-beta.
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| Gan Q, Li T, Hu B, Lian M, Zheng X.
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| J Cell Sci 122(Pt 22):4081-8. doi: 10.1242/jcs.054007. Epub 2009 Oct 20.
2009
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7 | COMMD1, NMRAL1
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| HSCARG regulates NF-kappaB activation by promoting the ubiquitination of RelA or COMMD1.
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| Lian M, Zheng X.
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| J Biol Chem 284(27):17998-8006. doi: 10.1074/jbc.M809752200. Epub 2009 May 11.
2009
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8 | NMRAL1
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| NADPH is an allosteric regulator of HSCARG.
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| Dai X, Li Y, Meng G, Yao S, Zhao Y, Yu Q, Zhang J, Luo M, Zheng X.
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| J Mol Biol 387(5):1277-85. doi: 10.1016/j.jmb.2009.02.049. Epub 2009 Feb 28.
2009
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9 | NMRAL1
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| An NADPH sensor protein (HSCARG) down-regulates nitric oxide synthesis by association with argininosuccinate synthetase and is essential for epithelial cell viability.
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| Zhao Y, Zhang J, Li H, Li Y, Ren J, Luo M, Zheng X.
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| J Biol Chem 283(16):11004-13. doi: 10.1074/jbc.M708697200. Epub 2008 Feb 8.
2008
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10 | NMRAL1
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| Protein expression, crystallization and preliminary X-ray crystallographic studies on HSCARG from Homo sapiens.
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| Dai X, Gu X, Luo M, Zheng X.
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| Protein Pept Lett 13(9):955-7.
2006
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