| 1 | FBXO45, NMNAT2, SKP1
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| PAM forms an atypical SCF ubiquitin ligase complex that ubiquitinates and degrades NMNAT2.
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| Desbois M, Crawley O, Evans PR, Baker ST, Masuho I, Yasuda R, Grill B.
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| J Biol Chem 293(36):13897-13909. doi: 10.1074/jbc.RA118.002176. Epub 2018 Jul 11.
2018
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| 2 | NMNAT2
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| Two for the Price of One: A Neuroprotective Chaperone Kit within NAD Synthase Protein NMNAT2.
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| Lavado-Roldán A, Fernández-Chacón R.
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| PLoS Biol 14(7):e1002522. doi: 10.1371/journal.pbio.1002522. eCollection 2016 Jul.
2016
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| 3 | NMNAT2
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| NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.
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| Ali YO, Allen HM, Yu L, Li-Kroeger D, Bakhshizadehmahmoudi D, Hatcher A, McCabe C, Xu J, Bjorklund N, Taglialatela G, Bennett DA, De Jager PL, Shulman JM, Bellen HJ, Lu HC.
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| PLoS Biol 14(6):e1002472. doi: 10.1371/journal.pbio.1002472. eCollection 2016 Jun.
2016
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| 4 | NMNAT2, SARM1
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| Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.
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| Gilley J, Orsomando G, Nascimento-Ferreira I, Coleman MP.
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| Cell Rep 10(12):1974-81. doi: 10.1016/j.celrep.2015.02.060. Epub 2015 Mar 26.
2015
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| 5 | NMNAT2
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| Identification of palmitoyltransferase and thioesterase enzymes that control the subcellular localization of axon survival factor nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2).
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| Milde S, Coleman MP.
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| J Biol Chem 289(47):32858-70. doi: 10.1074/jbc.M114.582338. Epub 2014 Sep 30.
2014
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| 6 | NMNAT2
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| The NAD+ synthesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT-2) is a p53 downstream target.
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| Pan LZ, Ahn DG, Sharif T, Clements D, Gujar SA, Lee PW.
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| Cell Cycle 13(6):1041-8. doi: 10.4161/cc.28128. Epub 2014 Feb 7.
2014
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| 7 | LYPLA1, LYPLA2, NMNAT2
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| Identification of palmitoyltransferase and thioesterase enzymes that control the subcellular localization of axon survival factor nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2)
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| Milde S, Coleman MP.
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| Nov 21;289(47):32858-70. doi: 10.1074/jbc.M114.582338. Epub 2014 Sep 30. J Biol Chem. 2014
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| 8 | NMNAT2
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| Deletions within its subcellular targeting domain enhance the axon protective capacity of Nmnat2 in vivo.
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| Milde S, Fox AN, Freeman MR, Coleman MP.
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| Sci Rep 3:2567. doi: 10.1038/srep02567.
2013
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| 9 | NMNAT2
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| Subcellular localization determines the stability and axon protective capacity of axon survival factor Nmnat2.
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| Milde S, Gilley J, Coleman MP.
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| PLoS Biol 11(4):e1001539. doi: 10.1371/journal.pbio.1001539. Epub 2013 Apr 16.
2013
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| 10 | MAPT, NMNAT2, PPP2CA
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| Nmnat2 attenuates Tau phosphorylation through activation of PP2A.
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| Cheng XS, Zhao KP, Jiang X, Du LL, Li XH, Ma ZW, Yao J, Luo Y, Duan DX, Wang JZ, Zhou XW.
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| J Alzheimers Dis 36(1):185-95. doi: 10.3233/JAD-122173.
2013
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| 11 | NMNAT2
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| Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo.
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| Hicks AN, Lorenzetti D, Gilley J, Lu B, Andersson KE, Miligan C, Overbeek PA, Oppenheim R, Bishop CE.
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| PLoS One 7(10):e47869. doi: 10.1371/journal.pone.0047869. Epub 2012 Oct 17.
2012
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| 12 | NMNAT2
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| Nmnat2 protects cardiomyocytes from hypertrophy via activation of SIRT6.
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| Cai Y, Yu SS, Chen SR, Pi RB, Gao S, Li H, Ye JT, Liu PQ.
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| FEBS Lett 586(6):866-74. doi: 10.1016/j.febslet.2012.02.014. Epub 2012 Feb 20.
2012
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| 13 | NMNAT2
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| CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy.
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| Ljungberg MC, Ali YO, Zhu J, Wu CS, Oka K, Zhai RG, Lu HC.
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| Hum Mol Genet 21(2):251-67. doi: 10.1093/hmg/ddr492. Epub 2011 Oct 25.
2012
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| 14 | NMNAT1, NMNAT2, NMNAT3
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| Unique expression pattern of human nicotinamide mononucleotide adenylyltransferase isozymes in red blood cells.
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| Di Stefano M, Galassi L, Magni G.
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| Blood Cells Mol Dis 45(1):33-9. doi: 10.1016/j.bcmd.2010.04.003. Epub 2010 May 10.
2010
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| 15 | NMNAT2
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| Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons.
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| Gilley J, Coleman MP.
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| PLoS Biol 8(1):e1000300. doi: 10.1371/journal.pbio.1000300.
2010
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| 16 | NMNAT2
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| Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2.
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| Mayer PR, Huang N, Dewey CM, Dries DR, Zhang H, Yu G.
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| J Biol Chem 285(51):40387-96. doi: 10.1074/jbc.M110.178913. Epub 2010 Oct 13.
2010
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| 17 | NMNAT1, NMNAT2, NMNAT3
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| Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration.
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| Yahata N, Yuasa S, Araki T.
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| J Neurosci 29(19):6276-84. doi: 10.1523/JNEUROSCI.4304-08.2009.
2009
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| 18 | NMNAT1, NMNAT2, NMNAT3
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| Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms.
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| Berger F, Lau C, Dahlmann M, Ziegler M.
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| J Biol Chem 280(43):36334-41. Epub 2005 Aug 23.
2005
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| 19 | NMNAT1, NMNAT2
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| Characterization of human brain nicotinamide 5'-mononucleotide adenylyltransferase-2 and expression in human pancreas.
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| Yalowitz JA, Xiao S, Biju MP, Antony AC, Cummings OW, Deeg MA, Jayaram HN.
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| Biochem J 377(Pt 2):317-26. 2004
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| 20 | NMNAT2
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| Identification of a novel human nicotinamide mononucleotide adenylyltransferase.
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| Raffaelli N, Sorci L, Amici A, Emanuelli M, Mazzola F, Magni G.
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| Biochem Biophys Res Commun 297(4):835-40. 2002
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| 21 | NMNAT2
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| Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase.
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| Emanuelli M, Carnevali F, Saccucci F, Pierella F, Amici A, Raffaelli N, Magni G.
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| J Biol Chem 276(1):406-12. 2001
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| 22 | C1orf14, C1orf18, C1orf20, C1orf21, C1orf23, C1orf26, C1orf27, CDC73, EDEM3, FAM129A, GLT25D2, NMNAT2, NPL, RGS8, SMG7, TRM1L, TSEN15
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| Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus.
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| Sood R, Bonner TI, Makalowska I, Stephan DA, Robbins CM, Connors TD,Morgenbesser SD, Su K, Faruque MU, Pinkett H, Graham C, Baxevanis AD, KlingerKW, Landes GM, Trent JM, Carpten JD.
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| Genomics 73(2):211-22. 2001
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| 23 | C1orf34, CDC42BPA, CEP170, CROCC, CROCC, CYHR1, DENND4B, DISC1, DNAJC6, FAM20B, FAM91A2, HS2ST1, IPP, KIF21B, MACF1, NMNAT2, NOS1AP, PDE4DIP, PLCH2, POGZ, RABGAP1L, RERE, RPRD2, SDC3, SLC35E2, SNX27, SRGAP2, SZT2, TMCC2, UBR4, ZBTB40
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| Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.
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| Seki N, Ohira M, Nagase T, Ishikawa K, Miyajima N, Nakajima D, Nomura N,Ohara O.
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| DNA Res 4(5):345-9. 1997
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