| 1 | NME1, NME2
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| Loss of the Metastasis Suppressor NME1, But Not of Its Highly Related Isoform NME2, Induces a Hybrid Epithelial-Mesenchymal State in Cancer Cells
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| Huna A, Nawrocki-Raby B, Padilla-Benavides T, Gavard J, Coscoy S, Bernard D, Boissan M.
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| Int J Mol Sci. Apr 2;22(7):3718. doi: 10.3390/ijms22073718 2021
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| 2 | NME2
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| Involvement of NDPK-B in Glucose Metabolism-Mediated Endothelial Damage via Activation of the Hexosamine Biosynthesis Pathway and Suppression of O-GlcNAcase Activity.
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| Chatterjee A, Eshwaran R, Poschet G, Lomada S, Halawa M, Wilhelm K, Schmidt M, Hammes HP, Wieland T, Feng Y.
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| Cells. Oct 19;9(10):2324. doi: 10.3390/cells9102324. 2020
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| 3 | DNM2, NME1, NME2
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| Metastasis Suppressors NME1 and NME2 Promote Dynamin 2 Oligomerization and Regulate Tumor Cell Endocytosis, Motility, and Metastasis.
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| Khan I, Gril B, Steeg PS.
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| Cancer Res. Sep 15;79(18):4689-4702. doi: 10.1158/0008-5472.CAN-19-0492. Epub 2019 Jul 16. 2019
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| 4 | NME1, NME2
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| The actions of NME1/NDPK-A and NME2/NDPK-B as protein kinases.
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| Attwood PV, Muimo R.
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| Lab Invest Mar;98(3):283-290. doi: 10.1038/labinvest.2017.125. Epub 2017 Dec 4. 2018
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| 5 | NME1, NME2, NME3, NME5, NME7, NME8
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| Nuclear functions of NME proteins
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| Puts GS, Leonard MK, Pamidimukkala NV, Snyder DE, Kaetzel DM.
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| Lab Invest. Feb;98(2):211-218. doi: 10.1038/labinvest.2017.109. Epub 2017 Oct 23 2018
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| 6 | IRF6, NME1, NME2
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| Disrupted IRF6-NME1/2 Complexes as a Cause of Cleft Lip/Palate.
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| Parada-Sanchez MT, Chu EY, Cox LL, Undurty SS, Standley JM, Murray JC, Cox TC.
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| J Dent Res. Oct;96(11):1330-1338. doi: 10.1177/0022034517723615. Epub 2017 Aug 2. 2017
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| 7 | KCNN4, NME2, PGAM5
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| Identification of PGAM5 as a Mammalian Protein Histidine Phosphatase that Plays a Central Role to Negatively Regulate CD4(+) T Cells.
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| Panda S, Srivastava S, Li Z, Vaeth M, Fuhs SR, Hunter T, Skolnik EY.
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| Mol Cell 63(3):457-69. doi: 10.1016/j.molcel.2016.06.021. Epub 2016 Jul 21.
2016
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| 8 | NME2, PTPRS
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| NME2 associates with PTPσ to transduce signals from chondroitin sulfate proteoglycans.
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| Hamasaki H, Fujitani M, Yamashita T.
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| Biochem Biophys Res Commun. Mar 18;471(4):522-7. doi: 10.1016/j.bbrc.2016.02.042. Epub 2016 Feb 16. 2016
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| 9 | NME1, NME2
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| Metastasis suppressors Nm23H1 and Nm23H2 differentially regulate neoplastic transformation and tumorigenesis
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| Tong Y, Yung LY, Wong YH.
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| Cancer Lett. Jun 1;361(2):207-17. doi: 10.1016/j.canlet.2015.02.050. Epub 2015 Mar 3 2015
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| 10 | MYC, NME2, PIWIL2
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| PIWIL2 induces c-Myc expression by interacting with NME2 and regulates c-Myc-mediated tumor cell proliferation
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| Yao Y, Li C, Zhou X, Zhang Y, Lu Y, Chen J, Zheng X, Tao D, Liu Y, Ma Y.
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| Oncotarget. Sep 30;5(18):8466-77. doi: 10.18632/oncotarget.2327 2014
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| 11 | NME2
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| Metastases suppressor NME2 associates with telomere ends and telomerase and reduces telomerase activity within cells.
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| Kar A, Saha D, Purohit G, Singh A, Kumar P, Yadav VK, Kumar P, Thakur RK, Chowdhury S.
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| Nucleic Acids Res. Mar;40(6):2554-65. doi: 10.1093/nar/gkr1109. Epub 2011 Dec 1. 2012
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| 12 | MDM2, NME2
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| MDM2 interacts with NME2 (non-metastatic cells 2, protein) and suppresses the ability of NME2 to negatively regulate cell motility
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| Polanski R, Maguire M, Nield PC, Jenkins RE, Park BK, Krawczynska K, Devling T, Ray-Sinha A, Rubbi CP, Vlatkovic N, Boyd MT.
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| Carcinogenesis. Aug;32(8):1133-42. doi: 10.1093/carcin/bgr070. Epub 2011 Apr 18. 2011
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| 13 | NME1, NME2, NME3, NME5, NME7, NME8
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| Nme protein family evolutionary history, a vertebrate perspective.
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| Desvignes T, Pontarotti P, Fauvel C, Bobe J.
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| BMC Evol Biol. Oct 23;9:256. doi: 10.1186/1471-2148-9-256. 2009
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| 14 | HERC5, NME2
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| Highly homologous HERC proteins localize to endosomes and exhibit specific interactions with hPLIC and Nm23B.
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| Hochrainer K, Kroismayr R, Baranyi U, Binder BR, Lipp J.
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| Cell Mol Life Sci 65(13):2105-17.PMID: 18535780 2008
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| 15 | NME1, NME2, NME3, NME4, NME5, NME1-NME2
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| Read-through transcript from NM23-H1 into the neighboring NM23-H2 gene encodes a novel protein, NM23-LV.
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| Valentijn LJ, Koster J, Versteeg R.
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| Genomics 87(4):483-9. Epub 2006 Jan 25. 2006
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| 16 | NME2, PDGFC, EID1, GSN
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| Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling.
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| Gordon GJ, Rockwell GN, Jensen RV, Rheinwald JG, Glickman JN, Aronson JP, Pottorf BJ, Nitz MD, Richards WG, Sugarbaker DJ, Bueno R.
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| Am J Pathol 166(6):1827-40. 2005
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| 17 | NME2
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| Nm23-H2 interacts with a G protein-coupled receptor to regulate its endocytosis through an Rac1-dependent mechanism.
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| Rochdi MD, Laroche G, Dupre E, Giguere P, Lebel A, Watier V, Hamelin E, Lepine MC, Dupuis G, Parent JL.
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| J Biol Chem 279(18):18981-9. Epub 2004 Feb 19. 2004
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| 18 | GNB2,NME2
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| Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta.,
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| Cuello F, Schulze RA, Heemeyer F, Meyer HE, Lutz S, Jakobs KH, Niroomand F, Wieland T.
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| J Biol Chem. 278:7220-6 2003
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| 19 | NME2
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| Expression of cell surface NM23 proteins of human leukemia cell lines of various cellular lineage and differentiation stages.
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| Okabe-Kado J, Kasukabe T, Honma Y.
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| Leuk Res 26(6):569-76. 2002
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| 20 | NME1, NME2, TSG17B
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| Isolation and characterization of new microsatellites at the nm23-H1 and nm23-H2 gene loci and application for loss of heterozygosity (LOH) analysis.
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| Seifert M, Theisinger B, Engel M, Seib T, Seitz G, Stolte M, Hilgert K, Welter C.
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| Hum Genet 100(5-6):515-9. 1997
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| 21 | NME1, NME2, NME3, NME4, NME5, NME6
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| Nucleoside diphosphate kinase. Investigation of the intersubunit contacts by site-directed mutagenesis and crystallography.
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| Karlsson A, Mesnildrey S, Xu Y, Morera S, Janin J, Veron M.
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| J Biol Chem 271(33):19928-34 1996
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| 22 | NME2
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| Characterization of the human NM23-H2 promoter region and localization of the microsatellite D17S396.
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| Seifert M, et al.
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| Biochem Biophys Res Commun 215 : 910-914. 1995
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| 23 | NME2
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| The human NME2 gene lies within 18kb of NMEI in chromosome 17.
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| Chandrasekharappa SC, et al.
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| Genes Chromosomes Cancer 6 : 245-248. 1993
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| 24 | NME2
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| Localization of a second NM23 gene, NME2, to chromosome 17q21-q22.
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| Kelsell DP, et al.
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| Genomics 17 : 522-524. 1993
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| 25 | NME2
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| Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis.
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| Postel EH, et al.
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| Science 261 : 478-480. 1993
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| 26 | NME1, NME2
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| Chromosomal localization and nucleoside diphosphate kinase activity of human metastasis-suppressor genes NM23-1 and NM23-2.
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| Backer JM, et al.
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| Oncogene 8 : 497-502. 1993
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| 27 | NME2
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| Identification of a second human nm23 gene, nm23-H2.
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| Stahl JA, Leone A, Rosengard AM, Porter L, King CR, Steeg PS.
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| Cancer Res 51(1):445-9 1991
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