Citations for
Metastasis Suppressor NME1 Directly Activates Transcription of the ALDOC Gene in Melanoma Cells.
Pamidimukkala NV, Leonard MK, Snyder D, McCorkle JR, Kaetzel DM.
Anticancer Res 38(11):6059-6068. doi: 10.21873/anticanres.12956. 2018
A splicing variant of NME1 negatively regulates NF-κB signaling and inhibits cancer metastasis by interacting with IKKβ.
You DJ, Park CR, Lee HB, Moon MJ, Kang JH, Lee C, Oh SH, Ahn C, Seong JY, Hwang JI.
J Biol Chem 289(25):17709-20. doi: 10.1074/jbc.M114.553552. Epub 2014 May 8. 2014
Role of binding and nucleoside diphosphate kinase A in the regulation of the cystic fibrosis transmembrane conductance regulator by AMP-activated protein kinase.
King JD Jr, Lee J, Riemen CE, Neumann D, Xiong S, Foskett JK, Mehta A, Muimo R, Hallows KR.
J Biol Chem 287(40):33389-400. Epub 2012 Aug 6. 2012
Thymic stromal lymphopoietin downregulates NME1 expression and promotes invasion in human trophoblasts via the activation of STAT3 signaling pathway.
Wang Y, Fan DX, Duan J, Li MQ, Zhu XY, Jin LP.
Clin Immunol 143(1):88-95. doi: 10.1016/j.clim.2012.01.013. Epub 2012 Feb 9. 2012
Metastasis suppressor NM23-H1 promotes repair of UV-induced DNA damage and suppresses UV-induced melanomagenesis.
Jarrett SG, Novak M, Dabernat S, Daniel JY, Mellon I, Zhang Q, Harris N, Ciesielski MJ, Fenstermaker RA, Kovacic D, Slominski A, Kaetzel DM.
Cancer Res 72(1):133-43. doi: 10.1158/0008-5472.CAN-11-1795. Epub 2011 Nov 11. 2012
Functional modulation of the metastatic suppressor Nm23-H1 by oncogenic viruses.
Saha A, Robertson ES.
FEBS Lett 585(20):3174-84. doi: 10.1016/j.febslet.2011.08.007. Epub 2011 Aug 11. Review. 2011
Expression of nm23-H1 is associated with poor prognosis in peripheral T-cell lymphoma, not otherwise specified.
Niitsu N, Nakamine H, Okamoto M.
Clin Cancer Res 17(9):2893-9. doi: 10.1158/1078-0432.CCR-10-2999. Epub 2011 Apr 8. 2011
Metastasis suppressor function of NM23-H1 requires its 3'-5' exonuclease activity.
Zhang Q, McCorkle JR, Novak M, Yang M, Kaetzel DM.
Int J Cancer 128(1):40-50. doi: 10.1002/ijc.25307. 2011
Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells.
Boissan M, De Wever O, Lizarraga F, Wendum D, Poincloux R, Chignard N, Desbois-Mouthon C, Dufour S, Nawrocki-Raby B, Birembaut P, Bracke M, Chavrier P, Gespach C, Lacombe ML.
Cancer Res 70(19):7710-22. doi: 10.1158/0008-5472.CAN-10-1887. Epub 2010 Sep 14. 2010
Nucleoside diphosphate kinase Nm23-H1 regulates chromosomal stability by activating the GTPase dynamin during cytokinesis.
Conery AR, Sever S, Harlow E.
Proc Natl Acad Sci U S A 107(35):15461-6. doi: 10.1073/pnas.1010633107. Epub 2010 Aug 16. 2010
Nm23-H1 can induce cell cycle arrest and apoptosis in B cells.
Choudhuri T, Murakami M, Kaul R, Sahu SK, Mohanty S, Verma SC, Kumar P, Robertson ES.
Cancer Biol Ther 9(12):1065-78. Epub 2010 Jun 11. 2010
Multiple functions of Nm23-H1 are regulated by oxido-reduction system.
Lee E, Jeong J, Kim SE, Song EJ, Kang SW, Lee KJ.
PLoS One 4(11):e7949. doi: 10.1371/journal.pone.0007949. 2009
IFI16 and NM23 bind to a common DNA fragment both in the P53 and the cMYC gene promoters.
Egistelli L, Chichiarelli S, Gaucci E, Eufemi M, Schininą ME, Giorgi A, Lascu I, Turano C, Giartosio A, Cervoni L.
J Cell Biochem 106(4):666-72. doi: 10.1002/jcb.22053. 2009
14NME1, NME4
The nucleoside diphosphate kinase D (NM23-H4) binds the inner mitochondrial membrane with high affinity to cardiolipin and couples nucleotide transfer with respiration.
Tokarska-Schlattner M, Boissan M, Munier A, Borot C, Mailleau C, Speer O, Schlattner U, Lacombe ML.
J Biol Chem 283(38):26198-207. Epub 2008 Jul 17. 2008
The suppressor of metastasis Nm23-H1 interacts with the Cdc42 Rho family member and the pleckstrin homology domain of oncoprotein Dbl-1 to suppress cell migration.
Murakami M, Meneses PI, Lan K, Robertson ES.
Cancer Biol Ther 7(5):677-88. 2008
Novel roles of NM23 proteins in skin homeostasis, repair and disease.
Braun S, Mauch C, Boukamp P, Werner S.
Oncogene 26(4):532-42. Epub 2006 Jul 24. 2007
Read-through transcript from NM23-H1 into the neighboring NM23-H2 gene encodes a novel protein, NM23-LV.
Valentijn LJ, Koster J, Versteeg R.
Genomics 87(4):483-9. Epub 2006 Jan 25. 2006
The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death.
Chowdhury D, Beresford PJ, Zhu P, Zhang D, Sung JS, Demple B, Perrino FW, Lieberman J.
Mol Cell 23(1):133-42. 2006
Understanding the molecular basis of the interaction between NDPK-A and AMPK alpha 1.
Crawford RM, Treharne KJ, Arnaud-Dabernat S, Daniel JY, Foretz M, Viollet B, Mehta A.
Mol Cell Biol 26(15):5921-31. Retraction in: Mol Cell Biol. 2008 Sep;28(18):5827. 2006
20MEN1, NME1
Menin, the multiple endocrine neoplasia type 1 gene product, exhibits GTP-hydrolyzing activity in the presence of the tumor metastasis suppressor nm23.
Yaguchi H, Ohkura N, Tsukada T, Yamaguchi K.
J Biol Chem 277(41):38197-204. Epub 2002 Jul 26. 2002
Identification of genes (SPON2 and c20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display.
Manda R, et al.
Genomics 61(1):5-14 1999
Gain of chromosome arm 17q is associated with unfavourable prognosis in neuroblastoma, but does not involve mutations in the somatostatin receptor 2(SSTR2) gene at 17q24.
Abel F, Ejeskar K, Kogner P, Martinsson T.
Br J Cancer 81(8):1402-9. 1999
Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation.
Zhu J, Tseng YH, Kantor JD, Rhodes CJ, Zetter BR, Moyers JS, Kahn CR.
Proc Natl Acad Sci U S A 96(26):14911-8. 1999
A point mutation of human nucleoside diphosphate kinase A found in aggressive neuroblastoma affects protein folding.
Lascu I, Schaertl S, Wang C, Sarger C, Giartosio A, Briand G, Lacombe ML, Konrad M.
J Biol Chem 272(25):15599-602. 1997
25NME1, NME2, TSG17B
Isolation and characterization of new microsatellites at the nm23-H1 and nm23-H2 gene loci and application for loss of heterozygosity (LOH) analysis.
Seifert M, Theisinger B, Engel M, Seib T, Seitz G, Stolte M, Hilgert K, Welter C.
Hum Genet 100(5-6):515-9. 1997
Loss of heterozygosity of the nm23-H1 gene in human renal cell carcinomas.
Bosnar MH, Pavelic K, Hrascan R, Zeljko Z, Krhen I, Marekoyic Z, Krizanac S, Pavelic J.
J Cancer Res Clin Oncol 123(9):485-8. 1997
27NME1, NME2, NME3, NME4, NME5, NME6
Nucleoside diphosphate kinase. Investigation of the intersubunit contacts by site-directed mutagenesis and crystallography.
Karlsson A, Mesnildrey S, Xu Y, Morera S, Janin J, Veron M.
J Biol Chem 271(33):19928-34 1996
28NME1, NME2P1
Isolation and characterization of the human genomic locus coding for the putative metastasis control gene nm23-H1.
Dooley S, Seib T, Engel M, Theisinger B, Janz H, Piontek K, Zang KD, Welter C.
Hum Genet 93 : 63-66. 1994
NME1 protein expression and loss of heterozygosity mutations in primary human breast tumors.
Cropp CS, et al.
J Natl Cancer Inst 86 : 1167-1169. 1994
Mutation in the nm23 gene is associated with metastasis in colorectal cancer.
Wang L, et al.
Cancer Res 53 : 717-720. 1993
31NME1, NME2
Chromosomal localization and nucleoside diphosphate kinase activity of human metastasis-suppressor genes NM23-1 and NM23-2.
Backer JM, et al.
Oncogene 8 : 497-502. 1993
The NM23 gene maps to human chromosome band 17q22 ans shows a restriction fragment length polymorphism with BglII.
Varesco L, et al.
Genes Chromosomes Cancer 4 : 84-88. 1992
Somatic allelic deletion of nm23 in human cancer.
Leone A, et al.
Cancer Res 51 : 2490-2493. 1991
Metastasis suppressor gene is mapped to human chromosome 17p11-qter.
Eddy RL, et al.
(HGM11) Cytogenet Cell Genet 58 : 2005. 1991
BgIII and EcoRI polymorphism of the human nm23-H1 gene (NME1).
YagŸe J, et al.
Nucleic Acids Res 19 : 6663. 1991
Association of low nm23 RNA levels in human primary infiltrating ductal breast carcinomas with lymph node involvement and other histopathological indicators of high metastatic potential.
Bevilacqua G, et al.
Cancer Res 49 : 5185-5190. 1991
A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase.
Biggs J, et al.
Cell 63 : 933-940. 1990
Dyctyostelium nucleoside diphosphate kinase is highly homologous to Nm23 an Awd proteins involved in mammalian tumor metastasis and Drosophila development.
Wallet V, et al.
J Natl Cancer Inst 82 : 1199-1202. 1990