1 | CARD8, DPP9, NLRP1
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| DPP9's Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation.
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| Griswold AR, Ball DP, Bhattacharjee A, Chui AJ, Rao SD, Taabazuing CY, Bachovchin DA.
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| ACS Chem Biol CS Chem Biol. 2019 Sep 20. doi: 10.1021/acschembio.9b00462. [Epub ahead of print]
2019
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2 | DPP8, DPP8, NLRP1
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| DPP8/9 inhibitors are universal activators of functional NLRP1 alleles.
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| Gai K, Okondo MC, Rao SD, Chui AJ, Ball DP, Johnson DC, Bachovchin DA.
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| Cell Death Dis 10(8):587. doi: 10.1038/s41419-019-1817-5.
2019
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3 | CARD8, DPP8, DPP9, NLRP1
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| DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages.
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| de Vasconcelos NM, Vliegen G, Gonçalves A, De Hert E, Martín-Pérez R, Van Opdenbosch N, Jallapally A, Geiss-Friedlander R, Lambeir AM, Augustyns K, Van Der Veken P, De Meester I, Lamkanfi M.
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| Life Sci Alliance 2(1). pii: e201900313. doi: 10.26508/lsa.201900313. Print 2019 Feb.
2019
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4 | JRPP, NLRP1
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| Homozygous NLRP1 gain-of-function mutation in siblings with a syndromic form of recurrent respiratory papillomatosis.
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| Drutman SB, Haerynck F, Zhong FL, Hum D, Hernandez NJ, Belkaya S, Rapaport F, de Jong SJ, Creytens D, Tavernier SJ, Bonte K, De Schepper S, van der Werff Ten Bosch J, Lorenzo-Diaz L, Wullaert A, Bossuyt X, Orth G, Bonagura VR, Béziat V, Abel L, Jouanguy E, Reversade B, Casanova JL.
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| Proc Natl Acad Sci U S A 116(38):19055-19063. doi: 10.1073/pnas.1906184116. Epub 2019 Sep 4.
2019
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5 | NLRC4, NLRP1, NLRP3
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| Novel aspects of the assembly and activation of inflammasomes with focus on the NLRC4 inflammasome.
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| Fusco WG, Duncan JA.
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| Int Immunol 30(5):183-193. doi: 10.1093/intimm/dxy009.
2018
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6 | NLRP1
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| NLRP1 promotes TGF-β1-induced myofibroblast differentiation in neonatal rat cardiac fibroblasts.
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| Zong J, Zhang H, Li FF, Liang K, Liu JL, Xu LH, Qian WH.
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| J Mol Histol 49(5):509-518. doi: 10.1007/s10735-018-9789-9. Epub 2018 Aug 18.
2018
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7 | NLRP1
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| Nuclear Localization Leucine-Rich-Repeat Protein 1 Deficiency Protects Against Cardiac Hypertrophy by Pressure Overload.
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| Zong J, Li FF, Liang K, Dai R, Zhang H, Yan L, Liu JL, Xu LH, Qian WH.
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| Cell Physiol Biochem 48(1):75-86. doi: 10.1159/000491664. Epub 2018 Jul 12.
2018
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8 | NLRP1
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| NLRP1 deficiency attenuates diabetic retinopathy (DR) in mice through suppressing inflammation response.
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| Li Y, Liu C, Wan XS, Li SW.
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| Biochem Biophys Res Commun 501(2):351-357. doi: 10.1016/j.bbrc.2018.03.148. Epub 2018 May 11.
2018
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9 | NLRP1
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| Association between NLPR1, NLPR3, and P2X7R Gene Polymorphisms with Partial Seizures.
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| Wang H, Xu P, Liao D, Dang R, He X, Guo Y, Jiang P.
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| Biomed Res Int 2017:9547902. doi: 10.1155/2017/9547902. Epub 2017 Apr 19.
2017
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10 | CASP5, IL17A, NLRP1
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| Th17 micro-milieu regulates NLRP1-dependent caspase-5 activity in skin autoinflammation.
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| Zwicker S, Hattinger E, Bureik D, Batycka-Baran A, Schmidt A, Gerber PA, Rothenfusser S, Gilliet M, Ruzicka T, Wolf R.
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| PLoS One 12(4):e0175153. doi: 10.1371/journal.pone.0175153. eCollection 2017.
2017
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11 | NLRP1, NLRP3
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| The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.
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| Saresella M, La Rosa F, Piancone F, Zoppis M, Marventano I, Calabrese E, Rainone V, Nemni R, Mancuso R, Clerici M.
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| Mol Neurodegener 11:23. doi: 10.1186/s13024-016-0088-1.
2016
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12 | NLRP1
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| Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation.
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| Kaushal V, Dye R, Pakavathkumar P, Foveau B, Flores J, Hyman B, Ghetti B, Koller BH, LeBlanc AC.
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| Cell Death Differ 22(10):1676-86. doi: 10.1038/cdd.2015.16. Epub 2015 Mar 6.
2015
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13 | NLRP1
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| NLRP1 L155H Polymorphism is a Risk Factor for Preeclampsia Development.
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| Pontillo A, Reis EC, Bricher PN, Vianna P, Diniz S, Fernandes KS, Chies JA, Sandrim V.
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| Am J Reprod Immunol 73(6):577-81. doi: 10.1111/aji.12353. Epub 2014 Dec 29.
2015
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14 | NLRP1
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| Structure of the NLRP1 caspase recruitment domain suggests potential mechanisms for its association with procaspase-1.
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| Jin T, Curry J, Smith P, Jiang J, Xiao TS.
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| Proteins 81(7):1266-70. doi: 10.1002/prot.24287. Epub 2013 Apr 20.
2013
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15 | NLRP1
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| NLRP1, a regulator of innate immunity associated with vitiligo.
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| D'Osualdo A, Reed JC.
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| Pigment Cell Melanoma Res 25(1):5-8. doi: 10.1111/j.1755-148X.2011.00942.x. Review.
2012
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16 | NLRC4, NLRP1, NLRP3, NLRP6
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| NOD-like receptors and the innate immune system: coping with danger, damage and death.
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| Kersse K, Bertrand MJ, Lamkanfi M, Vandenabeele P.
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| Cytokine Growth Factor Rev 22(5-6):257-76. Epub 2011 Oct 12.
2011
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17 | NLRP1
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| Fine-mapping of vitiligo susceptibility loci on chromosomes 7 and 9 and interactions with NLRP1 (NALP1).
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| Jin Y, Riccardi SL, Gowan K, Fain PR, Spritz RA.
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| J Invest Dermatol 130(3):774-83. doi: 10.1038/jid.2009.273. Epub 2009 Sep 3.
2010
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18 | NLRP1, NLRP10, NLRP11, NLRP12, NLRP13, NLRP14, NLRP2, NLRP3, NLRP4, NLRP5, NLRP6, NLRP7, NLRP8, NLRP9
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| Evolution and functional divergence of NLRP genes in mammalian reproductive systems.
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| Tian X, Pascal G, Monget P.
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| BMC Evol Biol 9:202.
2009
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19 | BCL2, BCL2L1, CASP1, CASP5, NLRP1
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| Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1.
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| Bruey JM, Bruey-Sedano N, Luciano F, Zhai D, Balpai R, Xu C, Kress CL, Bailly-Maitre B, Li X, Osterman A, Matsuzawa S, Terskikh AV, Faustin B, Reed JC.
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| Cell 129(1):45-56. 2007
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20 | NLRP1
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| NALP1 in vitiligo-associated multiple autoimmune disease.
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| Jin Y, Mailloux CM, Gowan K, Riccardi SL, LaBerge G, Bennett DC, Fain PR, Spritz RA.
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| N Engl J Med 356(12):1216-25. 2007
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21 | NLRP11, NLRP4, NLRP6, NLRP5, NLRP10, NLRP12, NLRP13, NLRP14, NLRP1, NLRP2, NLRP8, NLRP9
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| CATERPILLER: a novel gene family important in immunity, cell death, and diseases.
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| Ting JP, Davis BK.
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| Annu Rev Immunol 23:387-414. Review. 2005
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22 | NLRP1, CREBBp
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| NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells.
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| Sanz C, Calasanz MJ, Andreu E, Richard C, Prosper F, Fernandez-Luna JL.
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| Biochem J 384(Pt 2):281-6. 2004
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23 | NLRP1, NLRP10, NLRP11, NLRP12, NLRP13, NLRP14, NLRP2, NLRP3, NLRP4, NLRP5, NLRP6, NLRP7, NLRP8, NLRP9
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| NALPs: a novel protein family involved in inflammation.
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| Tschopp J, Martinon F, Burns K.
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| Nat Rev Mol Cell Biol 4(2):95-104. Review.
2003
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24 | PYCARD, CASP1, CASP5, NLRP1
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| The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta.
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| Martinon F, Burns K, Tschopp J.
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| Mol Cell 10(2):417-26. 2002
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25 | NLRP1
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| Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins.
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| Hlaing T, Guo RF, Dilley KA, Loussia JM, Morrish TA, Shi MM, Vincenz C, Ward PA.
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| J Biol Chem 276(12):9230-8. 2001
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26 | AKAP2, AMOTL2, ANKRD6, ARSG, ASXL1, ATG4B, BAHD1, BIRC6, BTBD3, C6orf84, CAMK2A, CAMKK2, CARD8, CHSY1, CORO2A, CPEB3, DIP2C, DLGAP4, DNAJC16, DNAJC9, DZIP1, EFR3B, EXOC6B, FAIM2, FASTKD2, FNBP4, INPP5F, LRCH1, NLGN4Y, NLRP1, NRXN2, PADI2, PCNX, PDS5B, PLEKHA6, PSD3, R3HDM2, RPH3A, SBNO2, SEZ6L, STK38L, TBC1D30, THOC5, TLL2, USP20, ZBTB1, ZFP30
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| Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
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| Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A,Kotani H, Nomura N, Ohara O.
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| DNA Res 6(1):63-70. 1999
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27 | BRD2, BRD3, NLRP1
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| Phylogeny and structure of the RING3 gene.
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| Thorpe KL, Abdulla S, Kaufman J, Trowsdale J, Beck S.
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| Immunogenetics 44(5):391-6. No abstract available. 1996
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