Citations for
1NKX3-2, SOX9
Interplay of Nkx3.2, Sox9 and Pax3 regulates chondrogenic differentiation of muscle progenitor cells.
Cairns DM, Liu R, Sen M, Canner JP, Schindeler A, Little DG, Zeng L.
PLoS One 7(7):e39642. doi: 10.1371/journal.pone.0039642. Epub 2012 Jul 2. 2012
2NKX3-2
Nkx3.2 promotes primary chondrogenic differentiation by upregulating Col2a1 transcription.
Kawato Y, Hirao M, Ebina K, Shi K, Hashimoto J, Honjo Y, Yoshikawa H, Myoui A.
PLoS One 7(4):e34703. doi: 10.1371/journal.pone.0034703. Epub 2012 Apr 12. 2012
3NKX3-2
Indian Hedgehog signalling triggers Nkx3.2 protein degradation during chondrocyte maturation.
Choi SW, Jeong DU, Kim JA, Lee B, Joeng KS, Long F, Kim DW.
Biochem J 443(3):789-98. doi: 10.1042/BJ20112062. 2012
4IHH, NKX3-2
Indian Hedgehog signalling triggers Nkx3.2 protein degradation during chondrocyte maturation.
Choi SW, Jeong DU, Kim JA, Lee B, Joeng KS, Long F, Kim DW.
Biochem J 443(3):789-98. doi: 10.1042/BJ20112062. 2012
5NKX3-2, RUNX2
Nkx3.2-induced suppression of Runx2 is a crucial mediator of hypoxia-dependent maintenance of chondrocyte phenotypes.
Kawato Y, Hirao M, Ebina K, Tamai N, Shi K, Hashimoto J, Yoshikawa H, Myoui A.
Biochem Biophys Res Commun 416(1-2):205-10. doi: 10.1016/j.bbrc.2011.11.026. Epub 2011 Nov 10. 2011
6IKBKG, NKX3-2
Exogenous signal-independent nuclear IkappaB kinase activation triggered by Nkx3.2 enables constitutive nuclear degradation of IkappaB-alpha in chondrocytes.
Yong Y, Choi SW, Choi HJ, Nam HW, Kim JA, Jeong DU, Kim DY, Kim YS, Kim DW.
Mol Cell Biol 31(14):2802-16. doi: 10.1128/MCB.00253-10. Epub 2011 May 23. 2011
7NKX3-2, SMMD
Homozygous inactivating mutations in the NKX3-2 gene result in spondylo-megaepiphyseal-metaphyseal dysplasia.
Hellemans J, Simon M, Dheedene A, Alanay Y, Mihci E, Rifai L, Sefiani A, van Bever Y, Meradji M, Superti-Furga A, Mortier G.
Am J Hum Genet 85(6):916-22.PMID: 20004766 2009
8NKX3-2
Sox9 directly promotes Bapx1 gene expression to repress Runx2 in chondrocytes.
Yamashita S, Andoh M, Ueno-Kudoh H, Sato T, Miyaki S, Asahara H.
Exp Cell Res 315(13):2231-40. doi: 10.1016/j.yexcr.2009.03.008. Epub 2009 Mar 21. 2009
9NKX3-2, RELA
Constitutive RelA activation mediated by Nkx3.2 controls chondrocyte viability.
Park M, Yong Y, Choi SW, Kim JH, Lee JE, Kim DW.
Nat Cell Biol 9(3):287-98. Epub 2007 Feb 18.PMID: 17310243 2007
10NKX3-2
Histone acetylation dependent allelic expression imbalance of BAPX1 in patients with the oculo-auriculo-vertebral spectrum.
Fischer S, Ludecke HJ, Wieczorek D, Bohringer S, Gillessen-Kaesbach G, Horsthemke B.
Hum Mol Genet 15(4):581-7. Epub 2006 Jan 11. 2006
11MEOX1, NKX3-2
Meox homeodomain proteins are required for Bapx1 expression in the sclerotome and activate its transcription by direct binding to its promoter.
Rodrigo I, Bovolenta P, Mankoo BS, Imai K.
Mol Cell Biol 24(7):2757-66. 2004
12NKX3-2
The murine Bapx1 homeobox gene plays a critical role in embryonic development of the axial skeleton and spleen.
Tribioli C, Lufkin T.
Development 126(24):5699-711. 1999
13NKX3-2
Sequence and chromosomal assignment of human BAPX1, a bagpipe-related gene, to 4p16.1: a candidate gene for skeletal dysplasia.
Yoshiura KI, Murray JC.
Genomics 45(2):425-8. 1997
14NKX3-2
Molecular cloning, chromosomal mapping and developmental expression of BAPX1, a novel human homeobox-containing gene homologous to Drosophila bagpipe.
Tribioli C, Lufkin T.
Gene 203(2):225-33. 1997
15NKX3-2
Bapx1: an evolutionary conserved homologue of the Drosophila bagpipe homeobox gene is expressed in splanchnic mesoderm and the embryonic skeleton.
Tribioli C, Frasch M, Lufkin T.
Mech Dev 65(1-2):145-62. 1997