Citations for
1AKT1, MAPK14, NFKBIA, TNFAIP8L2
TIPE2 Inhibits Lung Cancer Growth Attributing to Promotion of Apoptosis by Regulating Some Apoptotic Molecules Expression.
Liu QQ, Zhang FF, Wang F, Qiu JH, Luo CH, Zhu GY, Liu YF.
PLoS One 10(5):e0126176. doi: 10.1371/journal.pone.0126176. 2015
2ACTN4, NFKBIA, PDLIM1
PDLIM1 inhibits NF-κB-mediated inflammatory signaling by sequestering the p65 subunit of NF-κB in the cytoplasm.
Ono R, Kaisho T, Tanaka T.
Sci Rep 5:18327. doi: 10.1038/srep18327. 2015
3NFKBIA, ZBTB20
Zinc finger protein ZBTB20 promotes Toll-like receptor-triggered innate immune responses by repressing IκBα gene transcription.
Liu X, Zhang P, Bao Y, Han Y, Wang Y, Zhang Q, Zhan Z, Meng J, Li Y, Li N, Zhang WJ, Cao X.
Proc Natl Acad Sci U S A 110(27):11097-102. doi: 10.1073/pnas.1301257110. Epub 2013 Jun 17. 2013
4NFKBIA
IκBα is not required for axon initial segment assembly.
Buffington SA, Sobotzik JM, Schultz C, Rasband MN.
Mol Cell Neurosci 50(1):1-9. doi: 10.1016/j.mcn.2012.03.003. Epub 2012 Mar 15. 2012
5CD40, CD40LG, CHUK, NFKBIA
Involvement of nuclear factor κB in platelet CD40 signaling.
Hachem A, Yacoub D, Zaid Y, Mourad W, Merhi Y.
Biochem Biophys Res Commun 425(1):58-63. doi: 10.1016/j.bbrc.2012.07.049. Epub 2012 Jul 20. 2012
6NFKBIA
NFKBIA deletion in glioblastomas.
Takeuchi S, Nawashiro H.
N Engl J Med 365(3):276-7; author reply 277-8. doi: 10.1056/NEJMc1103354#SA1. No abstract available. 2011
7NFKBIA
Nuclear factor-kappa-B-inhibitor alpha (NFKBIA) is a developmental marker of NF-κB/p65 activation during in vitro oocyte maturation and early embryogenesis.
Paciolla M, Boni R, Fusco F, Pescatore A, Poeta L, Ursini MV, Lioi MB, Miano MG.
Hum Reprod 26(5):1191-201. doi: 10.1093/humrep/der040. Epub 2011 Feb 26. 2011
8NFKBIA
Monoallelic deletion of NFKBIA in glioblastoma: when less is more.
Rinkenbaugh AL, Baldwin AS.
Cancer Cell 19(2):163-5. doi: 10.1016/j.ccr.2011.01.045. 2011
9NFKBIA
NFKBIA deletion in glioblastomas
Bredel M, Scholtens DM, Yadav AK, Alvarez AA, Renfrow JJ, Chandler JP, Yu IL, Carro MS, Dai F, Tagge MJ, Ferrarese R, Bredel C, Phillips HS, Lukac PJ, Robe PA, Weyerbrock A, Vogel H, Dubner S, Mobley B, He X, Scheck AC, Sikic BI, Aldape KD, Chakravarti A, Harsh GR 4th.
N Engl J Med 364(7):627-37. doi: 10.1056/NEJMoa1006312. Epub 2010 Dec 22. 2011
10CASP1, NFKBIA
I-kappaBalpha depletion by transglutaminase 2 and mu-calpain occurs in parallel with the ubiquitin-proteasome pathway.
Kim DS, Han BG, Park KS, Lee BI, Kim SY, Bae CD.
Biochem Biophys Res Commun 399(2):300-6. doi: 10.1016/j.bbrc.2010.07.078. Epub 2010 Jul 24. 2010
11NFKBIA
Mutations of NFKBIA in biopsy specimens from Hodgkin lymphoma.
Liu X, Yu H, Yang W, Zhou X, Lu H, Shi D.
Cancer Genet Cytogenet 197(2):152-7. doi: 10.1016/j.cancergencyto.2009.11.005. 2010
12NFKBIA
Mutations of NFKBIA, encoding IkappaB alpha, are a recurrent finding in classical Hodgkin lymphoma but are not a unifying feature of non-EBV-associated cases.
Lake A, Shield LA, Cordano P, Chui DT, Osborne J, Crae S, Wilson KS, Tosi S, Knight SJ, Gesk S, Siebert R, Hay RT, Jarrett RF.
Int J Cancer 125(6):1334-42. doi: 10.1002/ijc.24502. 2009
13ADEDAID, NFKBIA
A novel mutation in NFKBIA/IKBA results in a degradation-resistant N-truncated protein and is associated with ectodermal dysplasia with immunodeficiency.
Lopez-Granados E, Keenan JE, Kinney MC, Leo H, Jain N, Ma CA, Quinones R, Gelfand EW, Jain A.
Hum Mutat 29(6):861-8. doi: 10.1002/humu.20740. 2008
14NFKBIA
Germline mutations and polymorphisms in the NFKBIA gene in Hodgkin lymphoma.
Osborne J, Lake A, Alexander FE, Taylor GM, Jarrett RF.
Int J Cancer 116(4):646-51. 2005
15ADEDAID, NFKBIA
A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency.
Courtois G, Smahi A, Reichenbach J, Doffinger R, Cancrini C, Bonnet M, Puel A, Chable-Bessia C, Yamaoka S, Feinberg J, Dupuis-Girod S, Bodemer C, Livadiotti S, Novelli F, Rossi P, Fischer A, Israel A, Munnich A, Le Deist F, Casanova JL.
J Clin Invest 112(7):1108-15. 2003
16NFKBIA
The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression.
Chang NS.
J Biol Chem 277(12):10323-31. 2002
17BAZ1A, KDM4C, MBIP, NFKBIA, PNN, SRP54
Identification of target genes within an amplicon at 14q12-q13 in esophageal squamous cell carcinoma.
Yasui K, Imoto I, Fukuda Y, Pimkhaokham A, Yang ZQ, Naruto T, Shimada Y, Nakamura Y, Inazawa J.
Genes Chromosomes Cancer 32(2):112-8. 2001
18NFKBIA
A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes.
Huang TT, Kudo N, Yoshida M, Miyamoto S.
Proc Natl Acad Sci U S A 97(3):1014-9. 2000
19NFKBIA, NFKBIB, NFKBIL1
Mechanisms by which Ikappa B proteins control NF-kapa B activity.
Simeonidis S, et al.
Proc Natl Acad Sci U S A 96 : 49-54. 1999
20NFKBIA
Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha.
Cabannes E, et al.
Oncogene 18(20):3063-70. 1999
21NFKBIA
An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IkappaBalpha.
Johnson C, Van Antwerp D, Hope TJ.
EMBO J 18(23):6682-6693 1999
22NFKBIA
Identification of a novel 300-kDa factor termed IkappaB alphaE3-F1 that is required for ubiquitinylation of IkappaB alpha.
Suzuki H, Kobayashi M, Takeuchi M, Furuichi K, Chiba T, Tanaka K.
FEBS Lett 458(3):343-8 1999
23NFKBIA, SUMO1
SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation.
Desterro JM, et al.
Mol Cell 2(2):233-9. 1998
24NFKBIA
Polymorphisms in the 3' untranslated region of the IkappaB/MAD-3 (NFKBI) gene located on chromosome 14.
Glavac D, et al.
Hum Genet 93 : 694-696. 1994
25NFKBIA, NFKB2
Chromosomal localization of the genes encoding the p50/p105 subunits of NF-kB (NFKB2) and the IkB/MAD-3 (NFKBI) inhibitor of NF-kB to 4q24 and 14q13, respectively.
Le Beau MM, et al.
Genomics 14 : 529-531. 1992
26NFKBIA
Characterization of an immediate early gene induced in adherent monocytes that encodes IkB-like activity.
Haskill S, et al.
Cell 65 : 1281-1289. 1991