| 1 | EXOC3, NFKBIA, RPS6KA2
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| Nuclear Translocation of p65 is Controlled by Sec6 via the Degradation of IκBα.
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| Tanaka T, Iino M.
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| J Cell Physiol 231(3):719-30. doi: 10.1002/jcp.25122.
2016
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| 2 | AKT1, MAPK14, NFKBIA, TNFAIP8L2
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| TIPE2 Inhibits Lung Cancer Growth Attributing to Promotion of Apoptosis by Regulating Some Apoptotic Molecules Expression.
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| Liu QQ, Zhang FF, Wang F, Qiu JH, Luo CH, Zhu GY, Liu YF.
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| PLoS One 10(5):e0126176. doi: 10.1371/journal.pone.0126176.
2015
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| 3 | ACTN4, NFKBIA, PDLIM1
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| PDLIM1 inhibits NF-κB-mediated inflammatory signaling by sequestering the p65 subunit of NF-κB in the cytoplasm.
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| Ono R, Kaisho T, Tanaka T.
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| Sci Rep 5:18327. doi: 10.1038/srep18327.
2015
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| 4 | NFKBIA, ZBTB20
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| Zinc finger protein ZBTB20 promotes Toll-like receptor-triggered innate immune responses by repressing IκBα gene transcription.
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| Liu X, Zhang P, Bao Y, Han Y, Wang Y, Zhang Q, Zhan Z, Meng J, Li Y, Li N, Zhang WJ, Cao X.
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| Proc Natl Acad Sci U S A 110(27):11097-102. doi: 10.1073/pnas.1301257110. Epub 2013 Jun 17.
2013
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| 5 | DDRGK1, NFKBIA
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| DDRGK1 regulates NF-κB activity by modulating IκBα stability.
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| Xi P, Ding D, Zhou J, Wang M, Cong YS.
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| PLoS One 8(5):e64231. doi: 10.1371/journal.pone.0064231. Print 2013.
2013
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| 6 | NFKBIA
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| IκBα is not required for axon initial segment assembly.
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| Buffington SA, Sobotzik JM, Schultz C, Rasband MN.
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| Mol Cell Neurosci 50(1):1-9. doi: 10.1016/j.mcn.2012.03.003. Epub 2012 Mar 15.
2012
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| 7 | CD40, CD40LG, CHUK, NFKBIA
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| Involvement of nuclear factor κB in platelet CD40 signaling.
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| Hachem A, Yacoub D, Zaid Y, Mourad W, Merhi Y.
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| Biochem Biophys Res Commun 425(1):58-63. doi: 10.1016/j.bbrc.2012.07.049. Epub 2012 Jul 20.
2012
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| 8 | NFKBIA
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| NFKBIA deletion in glioblastomas.
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| Takeuchi S, Nawashiro H.
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| N Engl J Med 365(3):276-7; author reply 277-8. doi: 10.1056/NEJMc1103354#SA1. No abstract available.
2011
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| 9 | NFKBIA
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| Nuclear factor-kappa-B-inhibitor alpha (NFKBIA) is a developmental marker of NF-κB/p65 activation during in vitro oocyte maturation and early embryogenesis.
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| Paciolla M, Boni R, Fusco F, Pescatore A, Poeta L, Ursini MV, Lioi MB, Miano MG.
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| Hum Reprod 26(5):1191-201. doi: 10.1093/humrep/der040. Epub 2011 Feb 26.
2011
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| 10 | NFKBIA
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| Monoallelic deletion of NFKBIA in glioblastoma: when less is more.
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| Rinkenbaugh AL, Baldwin AS.
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| Cancer Cell 19(2):163-5. doi: 10.1016/j.ccr.2011.01.045.
2011
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| 11 | NFKBIA
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| NFKBIA deletion in glioblastomas
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| Bredel M, Scholtens DM, Yadav AK, Alvarez AA, Renfrow JJ, Chandler JP, Yu IL, Carro MS, Dai F, Tagge MJ, Ferrarese R, Bredel C, Phillips HS, Lukac PJ, Robe PA, Weyerbrock A, Vogel H, Dubner S, Mobley B, He X, Scheck AC, Sikic BI, Aldape KD, Chakravarti A, Harsh GR 4th.
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| N Engl J Med 364(7):627-37. doi: 10.1056/NEJMoa1006312. Epub 2010 Dec 22. 2011
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| 12 | CASP1, NFKBIA
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| I-kappaBalpha depletion by transglutaminase 2 and mu-calpain occurs in parallel with the ubiquitin-proteasome pathway.
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| Kim DS, Han BG, Park KS, Lee BI, Kim SY, Bae CD.
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| Biochem Biophys Res Commun 399(2):300-6. doi: 10.1016/j.bbrc.2010.07.078. Epub 2010 Jul 24.
2010
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| 13 | NFKBIA
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| Mutations of NFKBIA in biopsy specimens from Hodgkin lymphoma.
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| Liu X, Yu H, Yang W, Zhou X, Lu H, Shi D.
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| Cancer Genet Cytogenet 197(2):152-7. doi: 10.1016/j.cancergencyto.2009.11.005.
2010
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| 14 | NFKBIA
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| Mutations of NFKBIA, encoding IkappaB alpha, are a recurrent finding in classical Hodgkin lymphoma but are not a unifying feature of non-EBV-associated cases.
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| Lake A, Shield LA, Cordano P, Chui DT, Osborne J, Crae S, Wilson KS, Tosi S, Knight SJ, Gesk S, Siebert R, Hay RT, Jarrett RF.
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| Int J Cancer 125(6):1334-42. doi: 10.1002/ijc.24502.
2009
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| 15 | ADEDAID, NFKBIA
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| A novel mutation in NFKBIA/IKBA results in a degradation-resistant N-truncated protein and is associated with ectodermal dysplasia with immunodeficiency.
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| Lopez-Granados E, Keenan JE, Kinney MC, Leo H, Jain N, Ma CA, Quinones R, Gelfand EW, Jain A.
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| Hum Mutat 29(6):861-8. doi: 10.1002/humu.20740.
2008
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| 16 | NFKBIA
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| Germline mutations and polymorphisms in the NFKBIA gene in Hodgkin lymphoma.
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| Osborne J, Lake A, Alexander FE, Taylor GM, Jarrett RF.
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| Int J Cancer 116(4):646-51.
2005
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| 17 | ADEDAID, NFKBIA
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| A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency.
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| Courtois G, Smahi A, Reichenbach J, Doffinger R, Cancrini C, Bonnet M, Puel A, Chable-Bessia C, Yamaoka S, Feinberg J, Dupuis-Girod S, Bodemer C, Livadiotti S, Novelli F, Rossi P, Fischer A, Israel A, Munnich A, Le Deist F, Casanova JL.
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| J Clin Invest 112(7):1108-15. 2003
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| 18 | NFKBIA
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| The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression.
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| Chang NS.
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| J Biol Chem 277(12):10323-31. 2002
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| 19 | BAZ1A, KDM4C, MBIP, NFKBIA, PNN, SRP54
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| Identification of target genes within an amplicon at 14q12-q13 in esophageal squamous cell carcinoma.
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| Yasui K, Imoto I, Fukuda Y, Pimkhaokham A, Yang ZQ, Naruto T, Shimada Y, Nakamura Y, Inazawa J.
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| Genes Chromosomes Cancer 32(2):112-8. 2001
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| 20 | NFKBIA
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| A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes.
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| Huang TT, Kudo N, Yoshida M, Miyamoto S.
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| Proc Natl Acad Sci U S A 97(3):1014-9. 2000
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| 21 | NFKBIA, NFKBIB, NFKBIL1
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| Mechanisms by which Ikappa B proteins control NF-kapa B activity.
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| Simeonidis S, et al.
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| Proc Natl Acad Sci U S A 96 : 49-54. 1999
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| 22 | NFKBIA
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| Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha.
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| Cabannes E, et al.
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| Oncogene 18(20):3063-70. 1999
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| 23 | NFKBIA
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| An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IkappaBalpha.
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| Johnson C, Van Antwerp D, Hope TJ.
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| EMBO J 18(23):6682-6693 1999
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| 24 | NFKBIA
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| Identification of a novel 300-kDa factor termed IkappaB alphaE3-F1 that is required for ubiquitinylation of IkappaB alpha.
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| Suzuki H, Kobayashi M, Takeuchi M, Furuichi K, Chiba T, Tanaka K.
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| FEBS Lett 458(3):343-8 1999
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| 25 | NFKBIA, SUMO1
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| SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation.
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| Desterro JM, et al.
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| Mol Cell 2(2):233-9. 1998
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| 26 | NFKBIA
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| Polymorphisms in the 3' untranslated region of the IkappaB/MAD-3 (NFKBI) gene located on chromosome 14.
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| Glavac D, et al.
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| Hum Genet 93 : 694-696. 1994
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| 27 | NFKBIA, NFKB2
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| Chromosomal localization of the genes encoding the p50/p105 subunits of NF-kB (NFKB2) and the IkB/MAD-3 (NFKBI) inhibitor of NF-kB to 4q24 and 14q13, respectively.
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| Le Beau MM, et al.
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| Genomics 14 : 529-531. 1992
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| 28 | NFKBIA
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| Characterization of an immediate early gene induced in adherent monocytes that encodes IkB-like activity.
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| Haskill S, et al.
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| Cell 65 : 1281-1289. 1991
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