1 | NFE2L1, VCP
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| Proteasome-mediated processing of Nrf1 is essential for coordinate induction of all proteasome subunits and p97.
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| Sha Z, Goldberg AL.
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| Curr Biol 24(14):1573-83. doi: 10.1016/j.cub.2014.06.004. Epub 2014 Jul 3.
2014
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2 | NFE2L1, SOX9
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| Expression profiling of Aldh1l1-precursors in the developing spinal cord reveals glial lineage-specific genes and direct Sox9-Nfe2l1 interactions.
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| Molofsky AV, Glasgow SM, Chaboub LS, Tsai HH, Murnen AT, Kelley KW, Fancy SP, Yuen TJ, Madireddy L, Baranzini S, Deneen B, Rowitch DH, Oldham MC.
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| Glia 61(9):1518-32. doi: 10.1002/glia.22538. Epub 2013 Jul 10.
2013
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3 | NFE2L1
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| Nuclear factor-erythroid 2-related factor 1 regulates expression of proteasome genes in hepatocytes and protects against endoplasmic reticulum stress and steatosis in mice.
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| Lee CS, Ho DV, Chan JY.
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| FEBS J 280(15):3609-20. doi: 10.1111/febs.12350. Epub 2013 Jun 18.
2013
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4 | GSK3B, NFE2L1
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| Glycogen synthase kinase 3 regulates expression of nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) and inhibits pro-survival function of Nrf1.
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| Biswas M, Kwong EK, Park E, Nagra P, Chan JY.
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| Exp Cell Res 319(13):1922-31. doi: 10.1016/j.yexcr.2013.04.013. Epub 2013 Apr 23.
2013
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5 | LPIN1, NFE2L1, PPARGC1B
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| NF-E2-related factor 1 (Nrf1) serves as a novel regulator of hepatic lipid metabolism through regulation of the Lipin1 and PGC-1β genes.
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| Hirotsu Y, Hataya N, Katsuoka F, Yamamoto M.
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| Mol Cell Biol 32(14):2760-70. doi: 10.1128/MCB.06706-11. Epub 2012 May 14.
2012
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6 | NFE2L1
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| Deficiency in the nuclear-related factor erythroid 2 transcription factor (Nrf1) leads to genetic instability.
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| Oh DH, Rigas D, Cho A, Chan JY.
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| FEBS J 279(22):4121-30. doi: 10.1111/febs.12005. Epub 2012 Oct 4.
2012
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7 | NFE2L1
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| Nrf1 CNC-bZIP protein promotes cell survival and nucleotide excision repair through maintaining glutathione homeostasis.
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| Han W, Ming M, Zhao R, Pi J, Wu C, He YY.
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| J Biol Chem 287(22):18788-95. doi: 10.1074/jbc.M112.363614. Epub 2012 Apr 12.
2012
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8 | NFE2L1
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| Long isoforms of NRF1 contribute to arsenic-induced antioxidant response in human keratinocytes.
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| Zhao R, Hou Y, Xue P, Woods CG, Fu J, Feng B, Guan D, Sun G, Chan JY, Waalkes MP, Andersen ME, Pi J.
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| Environ Health Perspect 119(1):56-62. Epub 2010 Aug 30.
2011
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9 | NFE2L1
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| TCF11 at the crossroads of oxidative stress and the ubiquitin proteasome system.
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| Koch A, Steffen J, Krüger E.
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| Cell Cycle 10(8):1200-7. Epub 2011 Apr 15.
2011
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10 | FBXW7, NFE2L1
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| The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis.
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| Biswas M, Phan D, Watanabe M, Chan JY.
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| J Biol Chem 286(45):39282-9. doi: 10.1074/jbc.M111.253807. Epub 2011 Sep 27.
2011
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11 | NFE2L1, NFE2L3
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| Identification of topological determinants in the N-terminal domain of transcription factor Nrf1 that control its orientation in the endoplasmic reticulum membrane.
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| Zhang Y, Hayes JD.
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| Biochem J 430(3):497-510.
2010
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12 | NFE2L1
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| Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells.
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| Radhakrishnan SK, Lee CS, Young P, Beskow A, Chan JY, Deshaies RJ.
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| Mol Cell 38(1):17-28.
2010
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13 | ACACB, NFE2L1, NRF1
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| AMPK activation represses the human gene promoter of the cardiac isoform of acetyl-CoA carboxylase: Role of nuclear respiratory factor-1.
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| Adam T, Opie LH, Essop MF.
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| Biochem Biophys Res Commun 398(3):495-9. Epub 2010 Jul 1. 2010
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14 | NFE2L1, NFE2L2
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| Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes.
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| Ohtsuji M, Katsuoka F, Kobayashi A, Aburatani H, Hayes JD, Yamamoto M.
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| J Biol Chem 283(48):33554-62. Epub 2008 Sep 30.
2008
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15 | LSS, NFE2L1
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| Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects.
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| Ma J, Dempsey AA, Stamatiou D, Marshall KW, Liew CC.
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| Atherosclerosis 191(1):63-72. Epub 2006 Jun 30. 2007
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16 | NFE2L1
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| The NHB1 (N-terminal homology box 1) sequence in transcription factor Nrf1 is required to anchor it to the endoplasmic reticulum and also to enable its asparagine-glycosylation.
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| Zhang Y, Lucocq JM, Yamamoto M, Hayes JD.
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| Biochem J 408(2):161-72.PMID: 17705787 2007
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17 | NFE2L1
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| Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia.
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| Xu Z, Chen L, Leung L, Yen TS, Lee C, Chan JY.
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| Proc Natl Acad Sci U S A. 102(11):4120-5 2005
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18 | NFE2L1
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| Cellular localisation and nuclear export of the human bZIP transcription factor TCF11.
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| Husberg C, Murphy P, Bj¿rgo E, Kalland KH, Kolst¿ AB.
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| Biochim Biophys Acta 1640(2-3):143-51. 2003
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19 | NFE2L1
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| Two domains of the human bZIP transcription factor TCF11 are necessary for transactivation.
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| Husberg C, Murphy P, Martin E, Kolsto AB.
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| J Biol Chem 276(21):17641-52. 2001
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20 | NFE2L1
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| Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice.
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| Chan JY, Kwong M, Lu R, Chang J, Wang B, Yen TS, Kan YW.
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| EMBO J 17(6):1779-87. 1998
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21 | NFE2L1
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| Nrf1 in a complex with fosB, c-jun, junD and ATF2 forms the AP1 component at the TNF alpha promoter in stimulated mast cells.
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| Novotny V, Prieschl EE, Csonga R, Fabjani G, Baumruker T.
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| Nucleic Acids Res 26(23):5480-5. 1998
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22 | JUN, NFE2L1, NFE2L2
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| Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes.
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| Venugopal R, Jaiswal AK.
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| Oncogene. 17(24):3145-56. 1998
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23 | NFE2L1
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| Interaction of the CNC-bZIP factor TCF11/LCR-F1/Nrf1 with MafG: binding-site selection and regulation of transcription.
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| Johnsen O, Murphy P, Prydz H, Kolsto AB.
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| Nucleic Acids Res. 26(2):512-20. 1998
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24 | NFE2L1
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| Small Maf proteins interact with the human transcription factor TCF11/Nrf1/LCR-F1.
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| Johnsen O, Skammelsrud N, Luna L, Nishizawa M, Prydz H, Kolstø AB.
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| Nucleic Acids Res. 24(21):4289-97. 1996
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25 | NFE2, NFE2L1, NFE2L2
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| Chromosomal localization of the human NF-E2 family of bZiP transcription factors by fluorescence in situ hybridization.
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| Chan JY, et al.
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| Hum Genet 95 : 265-269. 1995
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26 | BTR, NFE2L1
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| Structural organization and mapping of the human TCF11 gene.
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| Luna L, Skammelsrud N, Johnsen O, Abel KJ, Weber BL, Prydz H, Kolsto AB.
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| Genomics 27(2):237-44. 1995
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27 | NFE2L1
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| Cloning and functional characterization of LCR-F1 : a bZIP transcription factor that activates erythroid-specific, human globin gene expression.
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| Caterina JJ, et al.
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| Nucleic Acids Res 22 : 2383-2391. 1994
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28 | NFE2L1
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| Molecular cloning of a putative novel human bZIP transcription factor on chromosome 17q22.
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| Luna L, Johnsen O, Skartlien AH, Pedeutour F, Turc-Carel C, Prydz H, Kolsto AB.
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| Genomics 22(3):553-62. 1994
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29 | NFE2L1
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| Cloning of Nrf1, NF-E2-related transcription factor, by genetic selection in yeast.
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| Chan JY, et al.
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| Proc Natl Acad Sci U S A 90 : 11371-11375. 1993
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