| 1 | CACNA1C, NFATC4
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| NFATc4 and myocardin synergistically up-regulate the expression of LTCC α1C in ET-1-induced cardiomyocyte hypertrophy.
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| Li M, He HP, Gong HQ, Zhang J, Ma WJ, Zhou H, Cao DS, Wang N, Zhang TC.
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| Life Sci 155:11-20. doi: 10.1016/j.lfs.2016.05.007. Epub 2016 May 4.
2016
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| 2 | ID2, NFATC4
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| Transcriptional Profiling of Hypoxic Neural Stem Cells Identifies Calcineurin-NFATc4 Signaling as a Major Regulator of Neural Stem Cell Biology.
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| Moreno M, Fernández V, Monllau JM, Borrell V, Lerin C, de la Iglesia N.
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| Stem Cell Reports 5(2):157-65. doi: 10.1016/j.stemcr.2015.06.008. Epub 2015 Jul 30.
2015
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| 3 | BACE1, NFATC4
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| Transcriptional regulation of BACE1 by NFAT3 leads to enhanced amyloidogenic processing.
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| Mei Z, Yan P, Tan X, Zheng S, Situ B.
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| Neurochem Res 40(4):829-36. doi: 10.1007/s11064-015-1533-1. Epub 2015 Feb 7.
2015
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| 4 | NFATC3, NFATC4, TRIM17
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| Control of neuronal apoptosis by reciprocal regulation of NFATc3 and Trim17.
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| Mojsa B, Mora S, Bossowski JP, Lassot I, Desagher S.
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| Cell Death Differ. Feb;22(2):274-86. doi: 10.1038/cdd.2014.141. Epub 2014 Sep 12. 2015
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| 5 | NFATC4
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| Modulation of GABAA receptor signaling increases neurogenesis and suppresses anxiety through NFATc4.
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| Quadrato G, Elnaggar MY, Duman C, Sabino A, Forsberg K, Di Giovanni S.
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| J Neurosci 34(25):8630-45. doi: 10.1523/JNEUROSCI.0047-14.2014.
2014
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| 6 | MAPK7, NFATC4
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| Role of extracellular signal-regulated kinase 5 in adipocyte signaling.
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| Zhu H, Guariglia S, Li W, Brancho D, Wang ZV, Scherer PE, Chow CW.
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| J Biol Chem 289(9):6311-22. doi: 10.1074/jbc.M113.506584. Epub 2014 Jan 14.
2014
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| 7 | NFATC4
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| Up-regulation of NFATc4 involves in neuronal apoptosis following intracerebral hemorrhage.
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| Li L, Ke K, Tan X, Xu W, Shen J, Zhai T, Xu L, Rui Y, Zheng H, Zhai P, Zhao J, Cao M.
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| Cell Mol Neurobiol 33(7):893-905. doi: 10.1007/s10571-013-9955-2. Epub 2013 Jul 14.
2013
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| 8 | NFATC4, SDC4
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| Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress.
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| Herum KM, Lunde IG, Skrbic B, Florholmen G, Behmen D, Sjaastad I, Carlson CR, Gomez MF, Christensen G.
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| J Mol Cell Cardiol 54:73-81. doi: 10.1016/j.yjmcc.2012.11.006. Epub 2012 Nov 22.
2013
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| 9 | CITED2, NFATC4, NKX2-5, POU5F1
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| Cited2 gene controls pluripotency and cardiomyocyte differentiation of murine embryonic stem cells through Oct4 gene.
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| Li Q, Ramírez-Bergeron DL, Dunwoodie SL, Yang YC.
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| J Biol Chem 287(34):29088-100. doi: 10.1074/jbc.M112.378034. Epub 2012 Jul 3.
2012
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| 10 | BDNF, NFATC4
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| Nuclear factor of activated T cells (NFATc4) is required for BDNF-dependent survival of adult-born neurons and spatial memory formation in the hippocampus.
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| Quadrato G, Benevento M, Alber S, Jacob C, Floriddia EM, Nguyen T, Elnaggar MY, Pedroarena CM, Molkentin JD, Di Giovanni S.
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| Proc Natl Acad Sci U S A 109(23):E1499-508. doi: 10.1073/pnas.1202068109. Epub 2012 May 14.
2012
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| 11 | NFATC3, NFATC4
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| Distinct activation properties of the nuclear factor of activated T-cells (NFAT) isoforms NFATc3 and NFATc4 in neurons.
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| Ulrich JD, Kim MS, Houlihan PR, Shutov LP, Mohapatra DP, Strack S, Usachev YM.
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| J Biol Chem 287(45):37594-609. doi: 10.1074/jbc.M112.365197. Epub 2012 Sep 12.
2012
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| 12 | FOXP1, NFATC4
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| Opposing roles of FoxP1 and Nfat3 in transcriptional control of cardiomyocyte hypertrophy.
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| Bai S, Kerppola TK.
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| Mol Cell Biol 31(14):3068-80. Epub 2011 May 23.
2011
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| 13 | GPC6, NFATC1, NFATC2, NFATC3, NFATC4
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| NFAT promotes carcinoma invasive migration through glypican-6.
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| Yiu GK, Kaunisto A, Chin YR, Toker A.
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| Biochem J 440(1):157-66. doi: 10.1042/BJ20110530.
2011
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| 14 | LCN2, NFATC4
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| NFAT3 transcription factor inhibits breast cancer cell motility by targeting the Lipocalin 2 gene.
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| Fougère M, Gaudineau B, Barbier J, Guaddachi F, Feugeas JP, Auboeuf D, Jauliac S.
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| Oncogene 29(15):2292-301. Epub 2010 Jan 25.PMID: 20101218 2010
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| 15 | LPIN1, NFATC4
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| Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors.
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| Kim HB, Kumar A, Wang L, Liu GH, Keller SR, Lawrence JC Jr, Finck BN, Harris TE.
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| Mol Cell Biol 30(12):3126-39. Epub 2010 Apr 12.
2010
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| 16 | GAP43, NFATC4
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| NFAT-3 is a transcriptional repressor of the growth-associated protein 43 during neuronal maturation.
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| Nguyen T, Lindner R, Tedeschi A, Forsberg K, Green A, Wuttke A, Gaub P, Di Giovanni S.
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| J Biol Chem 284(28):18816-23. Epub 2009 May 14.
2009
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| 17 | MYH4, NFATC1, NFATC2, NFATC3, NFATC4
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| NFAT isoforms control activity-dependent muscle fiber type specification.
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| Calabria E, Ciciliot S, Moretti I, Garcia M, Picard A, Dyar KA, Pallafacchina G, Tothova J, Schiaffino S, Murgia M.
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| Proc Natl Acad Sci U S A 106(32):13335-40. Epub 2009 Jul 24.PMID: 19633193 2009
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| 18 | NFATC1, NFATC2, NFATC3, NFATC4
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| Alternative splicing and expression of human and mouse NFAT genes.
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| Vihma H, Pruunsild P, Timmusk T.
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| Genomics 92(5):279-91. Epub 2008 Aug 26.
2008
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| 19 | ESR1, ESR2, NFATC4
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| Repression of NFAT3 transcriptional activity by estrogen receptors.
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| Qin X, Wang XH, Yang ZH, Ding LH, Xu XJ, Cheng L, Niu C, Sun HW, Zhang H, Ye QN.
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| Cell Mol Life Sci 65(17):2752-62.
2008
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| 20 | NFATC4
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| Regulation of the stability and transcriptional activity of NFATc4 by ubiquitination.
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| Fan Y, Xie P, Zhang T, Zhang H, Gu D, She M, Li H.
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| FEBS Lett 582(29):4008-14. Epub 2008 Nov 19.
2008
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| 21 | NFATC4
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| Activation of the calcineurin/NFAT signalling cascade starts early in human hypertrophic myocardium.
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| Diedrichs H, Hagemeister J, Chi M, Boelck B, Müller-Ehmsen J, Schneider CA.
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| J Int Med Res 35(6):803-18.
2007
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| 22 | NFATC4
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| Nuclear factor of activated T3 is a negative regulator of Ras-JNK1/2-AP-1 induced cell transformation.
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| Yao K, Cho YY, Bergen HR 3rd, Madden BJ, Choi BY, Ma WY, Bode AM, Dong Z.
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| Cancer Res 67(18):8725-35.
2007
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| 23 | NFATC4, RPS6KA3
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| RSK2 mediates muscle cell differentiation through regulation of NFAT3.
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| Cho YY, Yao K, Bode AM, Bergen HR 3rd, Madden BJ, Oh SM, Ermakova S, Kang BS, Choi HS, Shim JH, Dong Z.
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| J Biol Chem 282(11):8380-92. Epub 2007 Jan 9.
2007
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| 24 | RCAN1, DYRK1A, NFATC1, NFATC2, NFATC3, NFATC4, TRI21
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| NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.
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| Arron JR, Winslow MM, Polleri A, Chang CP, Wu H, Gao X, Neilson JR, Chen L, Heit JJ, Kim SK, Yamasaki N, Miyakawa T, Francke U, Graef IA, Crabtree GR.
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| Nature 441(7093):595-600. Epub 2006 Mar 22. 2006
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| 25 | DYRK1A,NFATC1,NFATC2,NFATC3,NFATC4
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| A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT.
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| Gwack Y, Sharma S, Nardone J, Tanasa B, Iuga A, Srikanth S, Okamura H, Bolton D, Feske S, Hogan PG, Rao A.
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| Nature 441(7093):646-50. Epub 2006 Mar 1. 2006
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| 26 | NFATC1, NFATC2, NFATC3, NFATC4
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| NFAT is a nerve activity sensor in skeletal muscle and controls activity-dependent myosin switching.
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| McCullagh KJ, Calabria E, Pallafacchina G, Ciciliot S, Serrano AL, Argentini C, Kalhovde JM, Lomo T, Schiaffino S.
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| Proc Natl Acad Sci U S A 101(29):10590-5. Epub 2004 Jul 09. 2004
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| 27 | NFATC4
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| Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons.
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| Graef IA, Wang F, Charron F, Chen L, Neilson J, Tessier-Lavigne M, Crabtree GR.
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| Cell 113(5):657-70. 2003
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| 28 | GATA4, NFATC4, PPP3CA, PPP3CB
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| Polymorphisms of genes of the cardiac calcineurin pathway and cardiac hypertrophy.
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| Poirier O, Nicaud V, McDonagh T, Dargie HJ, Desnos M, Dorent R, Roizes G, Schwartz K, Tiret L, Komajda M, Cambien F.
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| Eur J Hum Genet 11(9):659-64. 2003
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| 29 | NFATC3, NFATC4
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| NFATc3 and NFATc4 are required for cardiac development and mitochondrial function.
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| Bushdid PB, Osinska H, Waclaw RR, Molkentin JD, Yutzey KE.
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| Circ Res 92(12):1305-13. Epub 2003 May 15. 2003
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| 30 | NFATC4, PPP3R1
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| Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature.
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| Graef IA, Chen F, Chen L, Kuo A, Crabtree GR.
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| Cell 105(7):863-75. 2001
|