Citations for
1NFATC2, NFATC3
Dynamic response diversity of NFAT isoforms in individual living cells.
Yissachar N, Sharar Fischler T, Cohen AA, Reich-Zeliger S, Russ D, Shifrut E, Porat Z, Friedman N.
Mol Cell 49(2):322-30. doi: 10.1016/j.molcel.2012.11.003. Epub 2012 Dec 6. 2013
2HDAC7, NFATC2, TNFSF11
HDAC7 inhibits osteoclastogenesis by reversing RANKL-triggered β-catenin switch.
Jin Z, Wei W, Dechow PC, Wan Y.
Mol Endocrinol 27(2):325-35. doi: 10.1210/me.2012-1302. Epub 2012 Nov 30. 2013
3NFATC2
Restricted heterochromatin formation links NFATc2 repressor activity with growth promotion in pancreatic cancer.
Baumgart S, Glesel E, Singh G, Chen NM, Reutlinger K, Zhang J, Billadeau DD, Fernandez-Zapico ME, Gress TM, Singh SK, Ellenrieder V.
Gastroenterology 142(2):388-98.e1-7. Epub 2011 Nov 10. 2012
4APOBECG, NFATC1, NFATC2
NFAT and IRF proteins regulate transcription of the anti-HIV gene, APOBEC3G.
Farrow MA, Kim EY, Wolinsky SM, Sheehy AM.
J Biol Chem 286(4):2567-77. Epub 2010 Nov 15. 2011
5IRF2BP2, NFATC2
Interferon regulatory factor 2 binding protein 2 is a new NFAT1 partner and represses its transcriptional activity.
Carneiro FR, Ramalho-Oliveira R, Mognol GP, Viola JP.
Mol Cell Biol 31(14):2889-901. Epub 2011 May 16. 2011
6NFATC2
Enhanced chromatin accessibility and recruitment of JUNB mediate the sustained IL-4 expression in NFAT1 deficient T helper 2 cells.
Son JS, Chae CS, Hwang JS, Park ZY, Im SH.
PLoS One 6(7):e22042. Epub 2011 Jul 25. 2011
7NFATC2
Osteomyelosclerosis, anemia and extramedullary hematopoiesis in mice lacking the transcription factor NFATc2.
Bauer W, Rauner M, Haase M, Kujawski S, Arabanian LS, Habermann I, Hofbauer LC, Ehninger G, Kiani A.
Haematologica 96(11):1580-8. Epub 2011 Jul 12. 2011
8NELL1, NFATC2
Nfatc2 is a primary response gene of Nell-1 regulating chondrogenesis in ATDC5 cells.
Chen W, Zhang X, Siu RK, Chen F, Shen J, Zara JN, Culiat CT, Tetradis S, Ting K, Soo C.
J Bone Miner Res 26(6):1230-41. doi: 10.1002/jbmr.314. 2011
9NFATC2
Nfat1 regulates adult articular chondrocyte function through its age-dependent expression mediated by epigenetic histone methylation.
Rodova M, Lu Q, Li Y, Woodbury BG, Crist JD, Gardner BM, Yost JG, Zhong XB, Anderson HC, Wang J.
J Bone Miner Res 26(8):1974-86. doi: 10.1002/jbmr.397. 2011
10NFATC2
NFAT1 transcription factor is central in the regulation of tissue microenvironment for tumor metastasis.
Werneck MB, Vieira-de-Abreu A, Chammas R, Viola JP.
Cancer Immunol Immunother 60(4):537-46. Epub 2011 Jan 12. 2011
11GPC6, NFATC1, NFATC2, NFATC3, NFATC4
NFAT promotes carcinoma invasive migration through glypican-6.
Yiu GK, Kaunisto A, Chin YR, Toker A.
Biochem J 440(1):157-66. doi: 10.1042/BJ20110530. 2011
12NFATC2
The C-terminal region of human NFATc2 binds cJun to synergistically activate interleukin-2 transcription.
Nguyen TN, Kim LJ, Walters RD, Drullinger LF, Lively TN, Kugel JF, Goodrich JA.
Mol Immunol 47(14):2314-22. Epub 2010 Jun 16. 2010
13NFATC2
NFAT1 mediates placental growth factor-induced myelomonocytic cell recruitment via the induction of TNF-alpha.
Ding Y, Huang Y, Song N, Gao X, Yuan S, Wang X, Cai H, Fu Y, Luo Y.
J Immunol 184(5):2593-601. Epub 2010 Jan 22. 2010
14MYH4, NFATC1, NFATC2, NFATC3, NFATC4
NFAT isoforms control activity-dependent muscle fiber type specification.
Calabria E, Ciciliot S, Moretti I, Garcia M, Picard A, Dyar KA, Pallafacchina G, Tothova J, Schiaffino S, Murgia M.
Proc Natl Acad Sci U S A 106(32):13335-40. Epub 2009 Jul 24.PMID: 19633193 2009
15NFATC2
NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure.
Bourajjaj M, Armand AS, da Costa Martins PA, Weijts B, van der Nagel R, Heeneman S, Wehrens XH, De Windt LJ.
J Biol Chem 283(32):22295-303. Epub 2008 May 12. 2008
16NFATC1, NFATC2, NFATC3, NFATC4
Alternative splicing and expression of human and mouse NFAT genes.
Vihma H, Pruunsild P, Timmusk T.
Genomics 92(5):279-91. Epub 2008 Aug 26. 2008
17NFATC2
Nuclear factor of activated T cell (NFAT) transcription proteins regulate genes involved in adipocyte metabolism and lipolysis.
Holowachuk EW.
Biochem Biophys Res Commun 361(2):427-32. Epub 2007 Jul 16. 2007
18NFATC2, RUNX2
Regulation of NFATc2 gene expression by the transcription factor Runx2.
Thirunavukkarasu K, Pei Y, Moore TL, Wei T, Wang H, Chandrasekhar S.
Mol Biol Rep 34(1):1-10. Epub 2006 Nov 11. 2007
19RCAN1, DYRK1A, NFATC1, NFATC2, NFATC3, NFATC4, TRI21
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.
Arron JR, Winslow MM, Polleri A, Chang CP, Wu H, Gao X, Neilson JR, Chen L, Heit JJ, Kim SK, Yamasaki N, Miyakawa T, Francke U, Graef IA, Crabtree GR.
Nature 441(7093):595-600. Epub 2006 Mar 22. 2006
20DYRK1A,NFATC1,NFATC2,NFATC3,NFATC4
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT.
Gwack Y, Sharma S, Nardone J, Tanasa B, Iuga A, Srikanth S, Okamura H, Bolton D, Feske S, Hogan PG, Rao A.
Nature 441(7093):646-50. Epub 2006 Mar 1. 2006
21AGTRAP, CAMLG, NFATC2, AGT
Identification of calcium-modulating cyclophilin ligand (CAML) as transducer of angiotensin II-mediated nuclear factor of activated T cells (NFAT) activation.
Guo S, Lopez-Ilasaca M, Dzau VJ.
J Biol Chem 280(13):12536-41. Epub 2005 Jan 24. 2005
22NFATC1, NFATC2, NFATC3, NFATC4
NFAT is a nerve activity sensor in skeletal muscle and controls activity-dependent myosin switching.
McCullagh KJ, Calabria E, Pallafacchina G, Ciciliot S, Serrano AL, Argentini C, Kalhovde JM, Lomo T, Schiaffino S.
Proc Natl Acad Sci U S A 101(29):10590-5. Epub 2004 Jul 09. 2004
23MEF2A, MEF2B, MEF2C, MEF2D, NFATC2
Myocyte enhancer factor 2 mediates calcium-dependent transcription of the interleukin-2 gene in T lymphocytes: a calcium signaling module that is distinct from but collaborates with the nuclear factor of activated T cells (NFAT).
Pan F, Ye Z, Cheng L, Liu JO.
J Biol Chem 279(15):14477-80. Epub 2004 Jan 13. 2004
24NFATC1, NFATC2
NFAT1 and NFAT2 are positive regulators of IL-4 gene transcription.
Monticelli S, Rao A.
Eur J Immunol 32(10):2971-8. 2002
25NFATC1, NFATC2, CD3G
Identification of three NFAT binding motifs in the 5'-upstream region of the human CD3gamma gene that differentially bind NFATc1, NFATc2, and NF-kappa B p50.
Badran BM, Wolinsky SM, Burny A, Willard-Gallo KE.
J Biol Chem 277(49):47136-48. Epub 2002 Oct 08. 2002
26NFATC1, NFATC2, NFATC3
A second calcineurin binding site on the NFAT regulatory domain.
Park S, Uesugi M, Verdine GL.
Proc Natl Acad Sci U S A 97(13):7130-5. 2000
27NFATC1, NFATC2
Cloning and chromosomal localization of the human and murine genes for the T-cell transcription factors NFATc and NFATp.
Li X, et al.
Cytogenet Cell Genet 68 : 185-191. 1995
28NFATC1, NFATC2
A similar DNA-binding motif in NFAT family proteins and the Rel homology region.
Jain J, Burgeon E, Badalian TM, Hogan PG, Rao A.
J Biol Chem 270(8):4138-45. 1995
29NFATC1, NFATC2
NF-AT components define a family of transcription factors targeted in T-cell activation.
Northrop JP, et al.
Nature 369 : 497-502. 1994
30NFATC2
The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun.
Jain J, McCaffrey PG, Miner Z, Kerppola TK, Lambert JN, Verdine GL, Curran T, Rao A.
Nature 365(6444):352-5. 1993