| 1 | NFATC2, NFATC3
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| Dynamic response diversity of NFAT isoforms in individual living cells.
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| Yissachar N, Sharar Fischler T, Cohen AA, Reich-Zeliger S, Russ D, Shifrut E, Porat Z, Friedman N.
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| Mol Cell 49(2):322-30. doi: 10.1016/j.molcel.2012.11.003. Epub 2012 Dec 6.
2013
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| 2 | HDAC7, NFATC2, TNFSF11
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| HDAC7 inhibits osteoclastogenesis by reversing RANKL-triggered β-catenin switch.
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| Jin Z, Wei W, Dechow PC, Wan Y.
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| Mol Endocrinol 27(2):325-35. doi: 10.1210/me.2012-1302. Epub 2012 Nov 30.
2013
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| 3 | NFATC2
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| Restricted heterochromatin formation links NFATc2 repressor activity with growth promotion in pancreatic cancer.
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| Baumgart S, Glesel E, Singh G, Chen NM, Reutlinger K, Zhang J, Billadeau DD, Fernandez-Zapico ME, Gress TM, Singh SK, Ellenrieder V.
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| Gastroenterology 142(2):388-98.e1-7. Epub 2011 Nov 10.
2012
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| 4 | APOBECG, NFATC1, NFATC2
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| NFAT and IRF proteins regulate transcription of the anti-HIV gene, APOBEC3G.
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| Farrow MA, Kim EY, Wolinsky SM, Sheehy AM.
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| J Biol Chem 286(4):2567-77. Epub 2010 Nov 15.
2011
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| 5 | IRF2BP2, NFATC2
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| Interferon regulatory factor 2 binding protein 2 is a new NFAT1 partner and represses its transcriptional activity.
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| Carneiro FR, Ramalho-Oliveira R, Mognol GP, Viola JP.
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| Mol Cell Biol 31(14):2889-901. Epub 2011 May 16.
2011
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| 6 | NFATC2
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| Enhanced chromatin accessibility and recruitment of JUNB mediate the sustained IL-4 expression in NFAT1 deficient T helper 2 cells.
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| Son JS, Chae CS, Hwang JS, Park ZY, Im SH.
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| PLoS One 6(7):e22042. Epub 2011 Jul 25.
2011
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| 7 | NFATC2
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| Osteomyelosclerosis, anemia and extramedullary hematopoiesis in mice lacking the transcription factor NFATc2.
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| Bauer W, Rauner M, Haase M, Kujawski S, Arabanian LS, Habermann I, Hofbauer LC, Ehninger G, Kiani A.
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| Haematologica 96(11):1580-8. Epub 2011 Jul 12.
2011
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| 8 | NELL1, NFATC2
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| Nfatc2 is a primary response gene of Nell-1 regulating chondrogenesis in ATDC5 cells.
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| Chen W, Zhang X, Siu RK, Chen F, Shen J, Zara JN, Culiat CT, Tetradis S, Ting K, Soo C.
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| J Bone Miner Res 26(6):1230-41. doi: 10.1002/jbmr.314.
2011
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| 9 | NFATC2
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| Nfat1 regulates adult articular chondrocyte function through its age-dependent expression mediated by epigenetic histone methylation.
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| Rodova M, Lu Q, Li Y, Woodbury BG, Crist JD, Gardner BM, Yost JG, Zhong XB, Anderson HC, Wang J.
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| J Bone Miner Res 26(8):1974-86. doi: 10.1002/jbmr.397.
2011
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| 10 | NFATC2
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| NFAT1 transcription factor is central in the regulation of tissue microenvironment for tumor metastasis.
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| Werneck MB, Vieira-de-Abreu A, Chammas R, Viola JP.
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| Cancer Immunol Immunother 60(4):537-46. Epub 2011 Jan 12.
2011
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| 11 | GPC6, NFATC1, NFATC2, NFATC3, NFATC4
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| NFAT promotes carcinoma invasive migration through glypican-6.
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| Yiu GK, Kaunisto A, Chin YR, Toker A.
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| Biochem J 440(1):157-66. doi: 10.1042/BJ20110530.
2011
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| 12 | NFATC2
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| The C-terminal region of human NFATc2 binds cJun to synergistically activate interleukin-2 transcription.
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| Nguyen TN, Kim LJ, Walters RD, Drullinger LF, Lively TN, Kugel JF, Goodrich JA.
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| Mol Immunol 47(14):2314-22. Epub 2010 Jun 16.
2010
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| 13 | NFATC2
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| NFAT1 mediates placental growth factor-induced myelomonocytic cell recruitment via the induction of TNF-alpha.
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| Ding Y, Huang Y, Song N, Gao X, Yuan S, Wang X, Cai H, Fu Y, Luo Y.
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| J Immunol 184(5):2593-601. Epub 2010 Jan 22.
2010
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| 14 | MYH4, NFATC1, NFATC2, NFATC3, NFATC4
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| NFAT isoforms control activity-dependent muscle fiber type specification.
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| Calabria E, Ciciliot S, Moretti I, Garcia M, Picard A, Dyar KA, Pallafacchina G, Tothova J, Schiaffino S, Murgia M.
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| Proc Natl Acad Sci U S A 106(32):13335-40. Epub 2009 Jul 24.PMID: 19633193 2009
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| 15 | NFATC2
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| NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure.
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| Bourajjaj M, Armand AS, da Costa Martins PA, Weijts B, van der Nagel R, Heeneman S, Wehrens XH, De Windt LJ.
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| J Biol Chem 283(32):22295-303. Epub 2008 May 12.
2008
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| 16 | NFATC1, NFATC2, NFATC3, NFATC4
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| Alternative splicing and expression of human and mouse NFAT genes.
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| Vihma H, Pruunsild P, Timmusk T.
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| Genomics 92(5):279-91. Epub 2008 Aug 26.
2008
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| 17 | NFATC2
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| Nuclear factor of activated T cell (NFAT) transcription proteins regulate genes involved in adipocyte metabolism and lipolysis.
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| Holowachuk EW.
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| Biochem Biophys Res Commun 361(2):427-32. Epub 2007 Jul 16. 2007
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| 18 | NFATC2, RUNX2
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| Regulation of NFATc2 gene expression by the transcription factor Runx2.
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| Thirunavukkarasu K, Pei Y, Moore TL, Wei T, Wang H, Chandrasekhar S.
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| Mol Biol Rep 34(1):1-10. Epub 2006 Nov 11.
2007
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| 19 | RCAN1, DYRK1A, NFATC1, NFATC2, NFATC3, NFATC4, TRI21
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| NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.
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| Arron JR, Winslow MM, Polleri A, Chang CP, Wu H, Gao X, Neilson JR, Chen L, Heit JJ, Kim SK, Yamasaki N, Miyakawa T, Francke U, Graef IA, Crabtree GR.
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| Nature 441(7093):595-600. Epub 2006 Mar 22. 2006
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| 20 | DYRK1A,NFATC1,NFATC2,NFATC3,NFATC4
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| A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT.
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| Gwack Y, Sharma S, Nardone J, Tanasa B, Iuga A, Srikanth S, Okamura H, Bolton D, Feske S, Hogan PG, Rao A.
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| Nature 441(7093):646-50. Epub 2006 Mar 1. 2006
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| 21 | AGTRAP, CAMLG, NFATC2, AGT
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| Identification of calcium-modulating cyclophilin ligand (CAML) as transducer of angiotensin II-mediated nuclear factor of activated T cells (NFAT) activation.
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| Guo S, Lopez-Ilasaca M, Dzau VJ.
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| J Biol Chem 280(13):12536-41. Epub 2005 Jan 24. 2005
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| 22 | NFATC1, NFATC2, NFATC3, NFATC4
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| NFAT is a nerve activity sensor in skeletal muscle and controls activity-dependent myosin switching.
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| McCullagh KJ, Calabria E, Pallafacchina G, Ciciliot S, Serrano AL, Argentini C, Kalhovde JM, Lomo T, Schiaffino S.
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| Proc Natl Acad Sci U S A 101(29):10590-5. Epub 2004 Jul 09. 2004
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| 23 | MEF2A, MEF2B, MEF2C, MEF2D, NFATC2
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| Myocyte enhancer factor 2 mediates calcium-dependent transcription of the interleukin-2 gene in T lymphocytes: a calcium signaling module that is distinct from but collaborates with the nuclear factor of activated T cells (NFAT).
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| Pan F, Ye Z, Cheng L, Liu JO.
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| J Biol Chem 279(15):14477-80. Epub 2004 Jan 13. 2004
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| 24 | NFATC1, NFATC2
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| NFAT1 and NFAT2 are positive regulators of IL-4 gene transcription.
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| Monticelli S, Rao A.
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| Eur J Immunol 32(10):2971-8. 2002
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| 25 | NFATC1, NFATC2, CD3G
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| Identification of three NFAT binding motifs in the 5'-upstream region of the human CD3gamma gene that differentially bind NFATc1, NFATc2, and NF-kappa B p50.
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| Badran BM, Wolinsky SM, Burny A, Willard-Gallo KE.
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| J Biol Chem 277(49):47136-48. Epub 2002 Oct 08. 2002
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| 26 | NFATC1, NFATC2, NFATC3
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| A second calcineurin binding site on the NFAT regulatory domain.
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| Park S, Uesugi M, Verdine GL.
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| Proc Natl Acad Sci U S A 97(13):7130-5. 2000
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| 27 | NFATC1, NFATC2
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| Cloning and chromosomal localization of the human and murine genes for the T-cell transcription factors NFATc and NFATp.
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| Li X, et al.
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| Cytogenet Cell Genet 68 : 185-191. 1995
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| 28 | NFATC1, NFATC2
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| A similar DNA-binding motif in NFAT family proteins and the Rel homology region.
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| Jain J, Burgeon E, Badalian TM, Hogan PG, Rao A.
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| J Biol Chem 270(8):4138-45. 1995
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| 29 | NFATC1, NFATC2
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| NF-AT components define a family of transcription factors targeted in T-cell activation.
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| Northrop JP, et al.
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| Nature 369 : 497-502. 1994
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| 30 | NFATC2
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| The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun.
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| Jain J, McCaffrey PG, Miner Z, Kerppola TK, Lambert JN, Verdine GL, Curran T, Rao A.
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| Nature 365(6444):352-5. 1993
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