Citations for
Arterial wall stress controls NFAT5 activity in vascular smooth muscle cells.
Scherer C, Pfisterer L, Wagner AH, Hödebeck M, Cattaruzza M, Hecker M, Korff T.
J Am Heart Assoc 3(2):e000626. doi: 10.1161/JAHA.113.000626. 2014
NFAT5 is protective against ischemic acute kidney injury.
Hao S, Bellner L, Zhao H, Ratliff BB, Darzynkiewicz Z, Vio CP, Ferreri NR.
Hypertension 63(3):e46-52. doi: 10.1161/HYPERTENSIONAHA.113.02476. Epub 2013 Dec 30. 2014
NFAT5 induction by the pre-T-cell receptor serves as a selective survival signal in T-lymphocyte development.
Berga-Bolaños R, Alberdi M, Buxadé M, Aramburu J, López-Rodríguez C.
Proc Natl Acad Sci U S A 110(40):16091-6. doi: 10.1073/pnas.1215934110. Epub 2013 Sep 16. 2013
NFAT5 represses canonical Wnt signaling via inhibition of β-catenin acetylation and participates in regulating intestinal cell differentiation.
Wang Q, Zhou Y, Rychahou P, Liu C, Weiss HL, Evers BM.
Cell Death Dis 4:e671. doi: 10.1038/cddis.2013.202. 2013
NFAT5-dependent expression of AQP4 in astrocytes.
Yi MH, Lee YS, Kang JW, Kim SJ, Oh SH, Kim YM, Lee YH, Lee SD, Kim DW.
Cell Mol Neurobiol 33(2):223-32. doi: 10.1007/s10571-012-9889-0. Epub 2012 Nov 20. 2013
Fat-specific protein 27 modulates nuclear factor of activated T cells 5 and the cellular response to stress.
Ueno M, Shen WJ, Patel S, Greenberg AS, Azhar S, Kraemer FB.
J Lipid Res 54(3):734-43. doi: 10.1194/jlr.M033365. Epub 2012 Dec 11. 2013
TAZ suppresses NFAT5 activity through tyrosine phosphorylation.
Jang EJ, Jeong H, Han KH, Kwon HM, Hong JH, Hwang ES.
Mol Cell Biol 32(24):4925-32. doi: 10.1128/MCB.00392-12. Epub 2012 Oct 8. 2012
NFAT5 regulates the canonical Wnt pathway and is required for cardiomyogenic differentiation.
Adachi A, Takahashi T, Ogata T, Imoto-Tsubakimoto H, Nakanishi N, Ueyama T, Matsubara H.
Biochem Biophys Res Commun 426(3):317-23. doi: 10.1016/j.bbrc.2012.08.069. Epub 2012 Aug 23. 2012
Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5.
Buxadé M, Lunazzi G, Minguillón J, Iborra S, Berga-Bolaños R, Del Val M, Aramburu J, López-Rodríguez C.
J Exp Med 209(2):379-93. doi: 10.1084/jem.20111569. Epub 2012 Feb 6. 2012
10DDX17, DDX5, NFAT5
Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor.
Germann S, Gratadou L, Zonta E, Dardenne E, Gaudineau B, Fougère M, Samaan S, Dutertre M, Jauliac S, Auboeuf D.
Oncogene 31(42):4536-49. doi: 10.1038/onc.2011.618. Epub 2012 Jan 23. 2012
Nuclear import of a lipid-modified transcription factor: mobilization of NFAT5 isoform a by osmotic stress.
Eisenhaber B, Sammer M, Lua WH, Benetka W, Liew LL, Yu W, Lee HK, Koranda M, Eisenhaber F, Adhikari S.
Cell Cycle 10(22):3897-911. doi: 10.4161/cc.10.22.18043. Epub 2011 Nov 15. 2011
Nuclear factor of activated T cells 5 regulates vascular smooth muscle cell phenotypic modulation.
Halterman JA, Kwon HM, Zargham R, Bortz PD, Wamhoff BR.
Arterioscler Thromb Vasc Biol 31(10):2287-96. doi: 10.1161/ATVBAHA.111.232165. Epub 2011 Jul 14. 2011
Phospholipase C-gamma1 is involved in signaling the activation by high NaCl of the osmoprotective transcription factor TonEBP/OREBP.
Irarrazabal CE, Gallazzini M, Schnetz MP, Kunin M, Simons BL, Williams CK, Burg MB, Ferraris JD.
Proc Natl Acad Sci U S A 107(2):906-11. Epub 2009 Dec 22.PMID: 20080774 2010
Contribution of SHP-1 protein tyrosine phosphatase to osmotic regulation of the transcription factor TonEBP/OREBP.
Zhou X, Gallazzini M, Burg MB, Ferraris JD.
Proc Natl Acad Sci U S A 107(15):7072-7. Epub 2010 Mar 29.PMID: 20351292 2010
15CD24, NFAT5
NFAT5 regulates T lymphocyte homeostasis and CD24-dependent T cell expansion under pathologic hypernatremia.
Berga-Bolaños R, Drews-Elger K, Aramburu J, López-Rodríguez C.
J Immunol 185(11):6624-35. Epub 2010 Oct 29. 2010
The expression of aquaporin-1 in the medulla of the kidney is dependent on the transcription factor associated with hypertonicity, TonEBP.
Lanaspa MA, Andres-Hernando A, Li N, Rivard CJ, Cicerchi C, Roncal-Jimenez C, Schrier RW, Berl T.
J Biol Chem 285(41):31694-703. doi: 10.1074/jbc.M109.093690. Epub 2010 Jul 16. 2010
Inducible nucleosome depletion at OREBP-binding-sites by hypertonic stress.
Tong EH, Guo JJ, Xu SX, Mak K, Chung SK, Chung SS, Huang AL, Ko BC.
PLoS One 4(12):e8435.PMID: 20041176 2009
Determination of the NFAT5/TonEBP transcription factor in the human and ovine placenta.
Arroyo JA, Teng C, Battaglia FC, Galan HL.
Syst Biol Reprod Med 55(4):164-70.PMID: 19886771 2009
19NFAT5, NUP88
Nucleoporin 88 (Nup88) is regulated by hypertonic stress in kidney cells to retain the transcription factor tonicity enhancer-binding protein (TonEBP) in the nucleus.
Andres-Hernando A, Lanaspa MA, Rivard CJ, Berl T.
J Biol Chem 283(36):25082-90. Epub 2008 Jul 7.PMID: 18606815 2008
Phosphorylation by casein kinase 1 regulates tonicity-induced osmotic response element-binding protein/tonicity enhancer-binding protein nucleocytoplasmic trafficking.
Xu S, Wong CC, Tong EH, Chung SS, Yates JR 3rd, Yin Y, Ko BC.
J Biol Chem 283(25):17624-34. Epub 2008 Apr 14.PMID: 18411282 2008
NFAT5 regulates HIV-1 in primary monocytes via a highly conserved long terminal repeat site.
Ranjbar S, Tsytsykova AV, Lee SK, Rajsbaum R, Falvo JV, Lieberman J, Shankar P, Goldfeld AE.
PLoS Pathog 2(12):e130.PMID: 17173480 2006
Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression.
Lopez-Rodriguez C, Antos CL, Shelton JM, Richardson JA, Lin F, Novobrantseva TI, Bronson RT, Igarashi P, Rao A, Olson EN.
Proc Natl Acad Sci U S A 101(8):2392-7. 2004
Assignment of transcription factor NFAT5 to human chromosome 16q22.1, murine chromosome 8D and porcine chromosome 6p1.4 and comparison of the polyglutamine domains.
Hebinck A, Dalski A, Engel H, Mattei M, Hawken R, Schwinger E, Zühlke C.
Cytogenet Cell Genet 90(1-2):68-70.PMID: 11060450 2000
NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun.
Lopez-Rodriguez C, Aramburu J, Rakeman AS, Rao A.
Proc Natl Acad Sci U S A 96(13):7214-9. 1999