Citations for
1CHL1, NF2, SEMA3B
Loss of cell adhesion molecule L1 like promotes tumor growth and metastasis in esophageal squamous cell carcinoma.
Tang H, Jiang L, Zhu C, Liu R, Wu Y, Yan Q, Liu M, Jia Y, Chen J, Qin Y, Lee VH, Luo S, Wang Q, Guan XY.
Oncogene 38(17):3119-3133. doi: 10.1038/s41388-018-0648-7. Epub 2019 Jan 8. 2019
2EZR, MSN, NF2, RDX
Two Sides of the Coin: Ezrin/Radixin/Moesin and Merlin Control Membrane Structure and Contact Inhibition.
Michie KA, Bermeister A, Robertson NO, Goodchild SC, Curmi PMG.
Int J Mol Sci 20(8). pii: E1996. doi: 10.3390/ijms20081996. Review. 2019
3LATS1, LATS2, NF2
Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2.
Yin F, Yu J, Zheng Y, Chen Q, Zhang N, Pan D.
Cell 154(6):1342-55. doi: 10.1016/j.cell.2013.08.025. Epub 2013 Sep 5. 2013
4LPIN2, NF2, NIPSNAP1, UGT2B17
Chromosomal structural variations during progression of a prostate epithelial cell line to a malignant metastatic state inactivate the NF2, NIPSNAP1, UGT2B17, and LPIN2 genes.
Malhotra A, Shibata Y, Hall IM, Dutta A.
Cancer Biol Ther 14(9):840-52. doi: 10.4161/cbt.25329. 2013
5NF2
Purification of the COP9 signalosome complex and binding partners from human T cells.
Stotland A, Pruitt L, Webster P, Wolkowicz R.
OMICS. 16(6):312-9. 2012
6MSN, NF2
The PP1 phosphatase flapwing regulates the activity of Merlin and Moesin in Drosophila.
Yang Y, Primrose DA, Leung AC, Fitzsimmons RB, McDermand MC, Missellbrook A, Haskins J, Smylie AS, Hughes SC.
Dev Biol 361(2):412-26. doi: 10.1016/j.ydbio.2011.11.007. Epub 2011 Nov 19. 2012
7NF2, SMARCB1
Germline SMARCB1 mutation and somatic NF2 mutations in familial multiple meningiomas.
Christiaans I, Kenter SB, Brink HC, van Os TA, Baas F, van den Munckhof P, Kidd AM, Hulsebos TJ.
J Med Genet 48(2):93-7. Epub 2010 Oct 7. 2011
8NF2
Missense mutations in the NF2 gene result in the quantitative loss of merlin protein and minimally affect protein intrinsic function.
Yang C, Asthagiri AR, Iyer RR, Lu J, Xu DS, Ksendzovsky A, Brady RO, Zhuang Z, Lonser RR.
Proc Natl Acad Sci U S A 108(12):4980-5. Epub 2011 Mar 7. 2011
9NF2
FERM domain phosphoinositide binding targets merlin to the membrane and is essential for its growth-suppressive function.
Mani T, Hennigan RF, Foster LA, Conrady DG, Herr AB, Ip W.
Mol Cell Biol 31(10):1983-96. Epub 2011 Mar 14. 2011
10NF2
Loss of tumor suppressor Merlin in advanced breast cancer is due to post-translational regulation.
Morrow KA, Das S, Metge BJ, Ye K, Mulekar MS, Tucker JA, Samant RS, Shevde LA.
J Biol Chem. 286(46):40376-85. 2011
11AMOT, ARHGAP17, NF2
A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions.
Yi C, Troutman S, Fera D, Stemmer-Rachamimov A, Avila JL, Christian N, Persson NL, Shimono A, Speicher DW, Marmorstein R, Holmgren L, Kissil JL.
Cancer Cell 19(4):527-40. doi: 10.1016/j.ccr.2011.02.017. 2011
12NF2, VPRBP
Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4(DCAF1) in the Nucleus.
Li W, You L, Cooper J, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG.
Cell 140(4):477-490. 2010
13NF2
Merlin in organ size control and tumorigenesis: Hippo versus EGFR?
Yi C, Kissil JL.
Genes Dev 24(16):1673-9. 2010
14NF2
Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver.
Benhamouche S, Curto M, Saotome I, Gladden AB, Liu CH, Giovannini M, McClatchey AI.
Genes Dev 24(16):1718-30. Epub 2010 Jul 30. 2010
15NF2
The neurofibromatosis 2 protein, merlin, regulates glial cell growth in an ErbB2- and Src-dependent manner.
Houshmandi SS, Emnett RJ, Giovannini M, Gutmann DH.
Mol Cell Biol 29(6):1472-86. Epub 2008 Dec 22. 2009
16NF2
Merlin regulates transmembrane receptor accumulation and signaling at the plasma membrane in primary mouse Schwann cells and in human schwannomas.
Lallemand D, Manent J, Couvelard A, Watilliaux A, Siena M, Chareyre F, Lampin A, Niwa-Kawakita M, Kalamarides M, Giovannini M.
Oncogene 28(6):854-65. Epub 2008 Nov 24. 2009
17MTOR, NF2
NF2/merlin is a novel negative regulator of mTOR complex 1, and activation of mTORC1 is associated with meningioma and schwannoma growth.
James MF, Han S, Polizzano C, Plotkin SR, Manning BD, Stemmer-Rachamimov AO, Gusella JF, Ramesh V.
Mol Cell Biol 29(15):4250-61. Epub 2009 May 18. 2009
18MPP1, NF2
Identification of erythrocyte p55/MPP1 as a binding partner of NF2 tumor suppressor protein/Merlin.
Seo PS, Quinn BJ, Khan AA, Zeng L, Takoudis CG, Hanada T, Bolis A, Bolino A, Chishti AH.
Exp Biol Med (Maywood) 234(3):255-62. Epub 2009 Jan 14.PMID: 19144871 2009
19SMARCB1, NF2
Molecular characterisation of SMARCB1 and NF2 in familial and sporadic schwannomatosis.
Hadfield KD, Newman WG, Bowers NL, Wallace A, Bolger C, Colley A, McCann E, Trump D, Prescott T, Evans DG.
J Med Genet 45(6):332-9. Epub 2008 Feb 19. 2008
20NF2
Nf2/merlin regulates hematopoietic stem cell behavior by altering microenvironmental architecture.
Larsson J, Ohishi M, Garrison B, Aspling M, Janzen V, Adams GB, Curto M, McClatchey AI, Schipani E, Scadden DT.
Cell Stem Cell 3(2):221-7.PMID: 18682243 2008
21NF2
Merlin is a potent inhibitor of glioma growth.
Lau YK, Murray LB, Houshmandi SS, Xu Y, Gutmann DH, Yu Q.
Cancer Res 68(14):5733-42.PMID: 18632626 2008
22NF2, VPRBP
VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation.
Huang J, Chen J.
Oncogene 27(29):4056-64. Epub 2008 Mar 10. 2008
23NF2
The tumor suppressor merlin interacts with microtubules and modulates Schwann cell microtubule cytoskeleton.
Muranen T, Gronholm M, Lampin A, Lallemand D, Zhao F, Giovannini M, Carpen O.
Hum Mol Genet 16(14):1742-51. Epub 2007 Jun 12. 2007
24GTPBP4, NF2
Identification and characterization of putative tumor suppressor NGB, a GTP-binding protein that interacts with the neurofibromatosis 2 protein.
Lee H, Kim D, Dan HC, Wu EL, Gritsko TM, Cao C, Nicosia SV, Golemis EA, Liu W, Coppola D, Brem SS, Testa JR, Cheng JQ.
Mol Cell Biol 27(6):2103-19. Epub 2007 Jan 8. 2007
25NF2
Akt phosphorylation regulates the tumour-suppressor merlin through ubiquitination and degradation.
Tang X, Jang SW, Wang X, Liu Z, Bahr SM, Sun SY, Brat D, Gutmann DH, Ye K.
Nat Cell Biol. 9(10):1199-207. 2007
26NF2
Ocular pathologic findings of neurofibromatosis type 2.
McLaughlin ME, Pepin SM, Maccollin M, Choopong P, Lessell S.
Arch Ophthalmol. 125(3):389-94. 2007
27EIF3C,NF2
Schwannomin inhibits tumorigenesis through direct interaction with the eukaryotic initiation factor subunit c (eIF3c).
Scoles DR, Yong WH, Qin Y, Wawrowsky K, Pulst SM.
Hum Mol Genet 15(7):1059-70. Epub 2006 Feb 23. 2006
28NF2, PPP1R14A
Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase.
Jin H, Sperka T, Herrlich P, Morrison H.
Nature 442(7102):576-9. 2006
29NF2
A functional association between merlin and HEI10, a cell cycle regulator.
Grönholm M, Muranen T, Toby GG, Utermark T, Hanemann CO, Golemis EA, Carpén O.
Oncogene. 25(32):4389-98 2006
30NF2
The merlin tumor suppressor interacts with Ral guanine nucleotide dissociation stimulator and inhibits its activity.
Ryu CH, Kim SW, Lee KH, Lee JY, Kim H, Lee WK, Choi BH, Lim Y, Kim YH, Lee KH, Hwang TK, Jun TY, Rha HK.
Oncogene 24(34):5355-64. 2005
31NF2, EZR
Characterization of the NF2 protein merlin and the ERM protein ezrin in human, rat, and mouse central nervous system.
Gronholm M, Teesalu T, Tyynela J, Piltti K, Bohling T, Wartiovaara K, Vaheri A, Carpen O.
Mol Cell Neurosci 28(4):683-93. 2005
32NF2, RALGDS
The merlin tumor suppressor interacts with Ral guanine nucleotide dissociation stimulator and inhibits its activity.
Ryu CH, Kim SW, Lee KH, Lee JY, Kim H, Lee WK, Choi BH, Lim Y, Kim YH, Lee KH, Hwang TK, Jun TY, Rha HK.
Oncogene 24(34):5355-64.PMID: 16007223 2005
33AGAP2, NF2
Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L.
Rong R, Tang X, Gutmann DH, Ye K.
Proc Natl Acad Sci U S A 101(52):18200-5. Epub 2004 Dec 14. 2004
34NF2, TARBP2
Merlin, a tumor suppressor, interacts with transactivation-responsive RNA-binding protein and inhibits its oncogenic activity.
Lee JY, Kim H, Ryu CH, Kim JY, Choi BH, Lim Y, Huh PW, Kim YH, Lee KH, Jun TY, Rha HK, Kang JK, Choi CR.
J Biol Chem 279(29):30265-73. Epub 2004 Apr 27. 2004
35MED28, NF2, GRB2
Magicin, a novel cytoskeletal protein associates with the NF2 tumor suppressor merlin and Grb2.
Wiederhold T, Lee MF, James M, Neujahr R, Smith N, Murthy A, Hartwig J, Gusella JF, Ramesh V.
Oncogene 23(54):8815-25. 2004
36NF2, SGSM3
MAP, a protein interacting with a tumor suppressor, merlin, through the run domain.
Lee IK, Kim KS, Kim H, Lee JY, Ryu CH, Chun HJ, Lee KU, Lim Y, Kim YH, Huh PW, Lee KH, Han SI, Jun TY, Rha HK.
Biochem Biophys Res Commun 325(3):774-83. 2004
37NF2
Molecular study of frequency of mosaicism in neurofibromatosis 2 patients with bilateral vestibular schwannomas
Kluwe L, Mautner V, Heinrich B, Dezube R, Jacoby LB, Friedrich RE, MacCollin M.
J Med Genet 40(2):109-14. 2003
38NF2
Genotype-phenotype correlations for cataracts in neurofibromatosis 2.
Baser ME, Kuramoto L, Joe H, Friedman JM, Wallace AJ, Ramsden RT, Evans DG.
J Med Genet 40(10):758-760. No abstract available. 2003
39SCWT, NF2
Familial schwannomatosis: exclusion of the NF2 locus as the germline event.
MacCollin M, Willett C, Heinrich B, Jacoby LB, Acierno JS Jr, Perry A, Louis DN.
Neurology 60(12):1968-74. 2003
40NF2, SCWT
Somatic instability of the NF2 gene in schwannomatosis.
Kaufman DL, Heinrich BS, Willett C, Perry A, Finseth F, Sobel RA, MacCollin M.
Arch Neurol 60(9):1317-20. 2003
41NF2
Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1.
Kissil JL, Wilker EW, Johnson KC, Eckman MS, Yaffe MB, Jacks T.
Mol Cell. 12(4):841-9. 2003
42NF2
NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions.
Lallemand D, Curto M, Saotome I, Giovannini M, McClatchey AI.
Genes Dev. 17(9):1090-100. 2003
43NF2, PXN, SCHIP1
Paxillin binds schwannomin and regulates its density-dependent localization and effect on cell morphology.
Fernandez-Valle C, Tang Y, Ricard J, Rodenas-Ruano A, Taylor A, Hackler E, Biggerstaff J, Iacovelli J.
Nat Genet 31(4):354-62. 2002
44NF2
Nucleocytoplasmic transfer of the NF2 tumor suppressor protein merlin is regulated by exon 2 and a CRM1-dependent nuclear export signal in exon 15.
Kressel M, Schmucker B.
Hum Mol Genet 11(19):2269-78. 2002
45NF2
Multiple transcription initiation sites, alternative splicing, and differential polyadenylation contribute to the complexity of human neurofibromatosis 2 transcripts.
Chang LS, Akhmametyeva EM, Wu Y, Zhu L, Welling DB.
Genomics. 79(1):63-76. 2002
46HGS, NF2
The NF2 interactor, hepatocyte growth factor-regulated tyrosine kinase substrate (HRS), associates with merlin in the 'open' conformation and suppresses cell growth and motility.
Gutmann DH, Haipek CA, Burke SP, Sun CX, Scoles DR, Pulst SM.
Hum Mol Genet 10(8):825-34. 2001
47NF2
High resolution deletion analysis of constitutional DNA from neurofibromatosis type 2 (NF2) patients using microarray-CGH.
Bruder CE, Hirvela C, Tapia-Paez I, Fransson I, Segraves R, Hamilton G, Zhang XX, Evans DG, Wallace AJ, Baser ME, Zucman-Rossi J, Hergersberg M, Boltshauser E, Papi L, Rouleau GA, Poptodorov G, Jordanova A, Rask-Andersen H, Kluwe L, Mautner V, Sainio M, Hung G, Mathiesen T, Moller C, Pulst SM, Harder H, Heiberg A, Honda M, Niimura M, Sahlen S, Blennow E, Albertson DG, Pinkel D, Dumanski JP.
Hum Mol Genet 10(3):271-82. 2001
48MEN1, NF2
Molecular genetic alterations on chromosomes 11 and 22 in ependymomas.
Lamszus K, Lachenmayer L, Heinemann U, Kluwe L, Finckh U, Hoppner W, Stavrou D, Fillbrandt R, Westphal M.
Int J Cancer 91(6):803-8. 2001
49NF2
276(35):33093-100.
Jannatipour M, Dion P, Khan S, Jindal H, Fan X, Laganière J, Chishti AH, Rouleau GA.
J Biol Chem. 276(35):33093-100. 2001
50NF2
Binding of the merlin-I product of the neurofibromatosis type 2 tumour suppressor gene to a novel site in beta-fodrin is regulated by association between merlin domains.
Neill GW, Crompton MR.
Biochem J. 358(Pt 3):727-35. 2001
51NF2
Functional analysis of the neurofibromatosis type 2 protein by means of disease-causing point mutations.
Stokowski RP, Cox DR.
Am J Hum Genet 66(3):873-91. 2000
52NF2
Molecular characterization of germline NF2 gene rearrangements.
Legoix P, Sarkissian HD, Cazes L, Giraud S, Sor F, Rouleau GA, Lenoir G, Thomas G, Zucman-Rossi J.
Genomics 65(1):62-6. 2000
53NF2
Clinical and molecular correlates of somatic mosaicism in neurofibromatosis 2.
Baser ME, Wallace AJ, Strachan T, Evans DG.
J Med Genet 37(7):542-3. No abstract available. 2000
54NF2, SCHIP1
Cloning and characterization of SCHIP-1, a novel protein interacting specifically with spliced isoforms and naturally occurring mutant NF2 proteins.
Goutebroze L, Brault E, Muchardt C, Camonis J, Thomas G.
Mol Cell Biol 20(5):1699-712. 2000
55HGS, NF2
The neurofibromatosis 2 tumor suppressor protein interacts with hepatocyte growth factor-regulated tyrosine kinase substrate.
Scoles DR, Huynh DP, Chen MS, Burke SP, Gutmann DH, Pulst SM.
Hum Mol Genet 9(11):1567-74. 2000
56NF2
Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2.
Giovannini M, Robanus-Maandag E, van der Valk M, Niwa-Kawakita M, Abramowski V, Goutebroze L, Woodruff JM, Berns A, Thomas G.
Genes Dev. 14(13):1617-30. 2000
57NF2
Increased expression of the NF2 tumor suppressor gene product, merlin, impairs cell motility, adhesion and spreading.
Gutmann DH, et al.
Hum Mol Genet 8 : 267-275. 1999
58NF2, TSG22A
Frequent mutations of NF2 and allelic loss from chromosome band 22q12 in malignant mesothelioma : evidence for a two-hit mechanism of NF2 inactivation.
Cheng JQ, et al.
Genes Chromosomes Cancer 24 : 238-242. 1999
59NF2
Germ-Line NF2 Mutations and Disease Severity in Neurofibromatosis Type 2 Patients with Retinal Abnormalities.
Baser ME, et al.
Am J Hum Genet 64(4):1230-1233. No abstract available 1999
60NF2, SCWT
A group of schwannomas with interstitial deletions on 22q located outside the NF2 locus shows no detectable mutations in the NF2 gene.
Bruder CE, et al.
Hum Genet 104(5):418-24. 1999
61NF2
Novel alternatively spliced isoforms of the neurofibromatosis type 2 tumor suppressor are targeted to the nucleus and cytoplasmic granules.
Schmucker B, et al.
Hum Mol Genet 8(8):1561-70. 1999
62NF2, TSG22A
Merlin: the neurofibromatosis 2 tumor suppressor.
Gusella JF, et al.
Biochim Biophys Acta 1423(2):M29-36. Review. 1999
63NF2, TSG22A
Tight association of loss of merlin expression with loss of heterozygosity at chromosome 22q in sporadic meningiomas.
Ueki K, Wen-Bin C, Narita Y, Asai A, Kirino T.
Cancer Res 59(23):5995-8. 1999
64NF2
Ezrin, a membrane-cytoskeletal linking protein, is involved in the process of invasion of endometrial cancer cells.
Ohtani K, Sakamoto H, Rutherford T, Chen Z, Satoh K, Naftolin F.
Cancer Lett 147(1-2):31-8. 1999
65NF2
Homotypic and heterotypic interaction of the neurofibromatosis 2 tumor suppressor protein merlin and the ERM protein ezrin.
Grönholm M, Sainio M, Zhao F, Heiska L, Vaheri A, Carpén O.
J Cell Sci. 112 ( Pt 6):895-904. 1999
66NF2
Impaired interaction of naturally occuring mutant NF2 protein with actin-based cytoskeleton and membrane.
Deguen B, Merel P, Goutebroze L, Giovannini M, Reggio H, Arpin M, Thomas G.
Hum Mol Genet 7(2):217-26. 1998
67NF2
A G-->A transition creates a branch point sequence and activation of a cryptic exon, resulting in the hereditary disorder neurofibromatosis 2.
De Klein A, Riegman PH, Bijlsma EK, Heldoorn A, Muijtjens M, den Bakker MA, Avezaat CJ, Zwarthoff EC.
Hum Mol Genet 7(3):393-8. 1998
68NF2
Defects in neurofibromatosis 2 protein function can arise at multiple levels.
Gutmann DH, Geist RT, Xu H, Kim JS, Saporito-Irwin S.
Hum Mol Genet 7(3):335-45. 1998
69NF2, TSG22A
Neurofibromatosis 2 tumour suppressor schwannomin interacts with betaII-spectrin.
Scoles DR, et al.
Nat Genet 18 : 354-359. 1998
70NF2
Localization and functional domains of the neurofibromatosis type II tumor suppressor, merlin.
Shaw RJ, et al.
Cell Growth Differ 9 : 287-296. 1998
71NF2
Genotype/phenotype correlations in type 2 neurofibromatosis (NF2) : evidence for more severe disease associated with truncating mutations.
Evans DGR, et al.
J Med Genet 35 : 450-455. 1998
72NF2
Phenotypic variability associated with 14 splice-site mutations in the NF2 gene.
Kluwe L, et al.
Am J Med Genet 77 : 228-233. 1998
73NF2, TSG22A
The involvement of calpain-dependent proteolysis of the tumor suppressor NF2 (merlin) in schwannomas and meningiomas.
Kimura Y, et al.
Nat Med 4 : 915-922. 1998
74NF2
Somatic mosaicism : a common cause of classic disease in tumor-prone syndromes? Lessons from type 2 neurofibromatosis.
Evans DGR, et al.
Am J Hum Genet 63 : 727-736. 1998
75NF2
Differential diagnosis of type 2 neurofibromatosis : molecular discrimination of NF2 and sporadic vestibular schwannomas.
Wu CL, et al.
J Med Genet 35 : 973-977. 1998
76NF2
NF2 gene in neurofibromatosis type 2 patients.
Zucman-Rossi J, et al.
Hum Mol Genet 7 : 2095-2101. 1998
77NF2
Mosaicism in sporadic neurofibromatosis 2 patients.
Kluwe L, et al.
Hum Mol Genet 7 : 2051-2055. 1998
78EPB41, EPB41L2, KRIT1, MSN, MYO15A, MYO7A, NF2, PTPN14, PTPN21, PTPN3, RDX, EZR
The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane.
Chishti AH, Kim AC, Marfatia SM, Lutchman M, Hanspal M, Jindal H, Liu SC, Low PS, Rouleau GA, Mohandas N, Chasis JA, Conboy JG, Gascard P, Takakuwa Y, Huang SC, Benz EJ Jr, Bretscher A, Fehon RG, Gusella JF, Ramesh V, Solomon F, Marchesi VT, Tsukita S, Tsukita S, Hoover KB, et al.
Trends Biochem Sci 23(8):281-2. Review. No abstract available 1998
79NF2
Merlin differs from moesin in binding to F-actin and in its intra- and intermolecular interactions.
Huang L, Ichimaru E, Pestonjamasp K, Cui X, Nakamura H, Lo GY, Lin FI, Luna EJ, Furthmayr H.
Biochem Biophys Res Commun. 248(3):548-53. 1998
80NF2, SLC9A3R1
NHE-RF, a regulatory cofactor for Na(+)-H+ exchange, is a common interactor for merlin and ERM (MERM) proteins.
Murthy A, Gonzalez-Agosti C, Cordero E, Pinney D, Candia C, Solomon F, Gusella J, Ramesh V.
J Biol Chem. 273(3):1273-6. 1998
81NF2
The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation.
McClatchey AI, Saotome I, Ramesh V, Gusella JF, Jacks T.
Genes Dev 11(10):1253-65. 1997
82NF2, SCWT, TSG22A
Molecular analysis of the NF2 tumor-suppressor gene in schwannomatosis.
Jacoby LB, Jones D, Davis K, Kronn D, Short MP, Gusella J, MacCollin M.
Am J Hum Genet 61(6):1293-302. 1997
83NF2, SCWT
Spinal and cutaneous schwannomatosis is a variant form of type 2 neurofibromatosis: a clinical and molecular study.
Evans DG, Mason S, Huson SM, Ponder M, Harding AE, Strachan T.
J Neurol Neurosurg Psychiatry 62(4):361-6. 1997
84NF2, TSG22A
Identification of three neurofibromatosis type 2 (NF2) gene mutations in vestibular schwannomas.
Sainz J, et al.
Hum Genet 97 : 121-123. 1996
85NF2, TSG22A
Screening for mutations in the neurofibromatosis type 2 (NF2) gene in sporadic meningiomas.
De Vitis LR, et al.
Hum Genet 97 : 632-637. 1996
86NF2, TSG22A
Analysis of the neurofibromatosis type 2 gene in different human tumors of neuroectodermal origin.
De Vitis LR, et al.
Hum Genet 97 : 638-641. 1996
87NF2
Phenotypic variability in two families with novel splice-site and frameshift NF2 mutations.
Mautner VF, et al.
Hum Genet 98 : 203-206. 1996
88TSG22A, NF2
Mutational spectrum in the neurofibromatosis type 2 gene in sporadic and familial schwannomas.
Welling DB, et al.
Hum Genet 98 : 189-193. 1996
89NF2
Type of mutation in the neurofibromatosis type 2 gene (NF2) frequently determines severity of disease.
Ruttledge MH, et al.
Am J Hum Genet 59 : 331-342. 1996
90NF2
A missense mutation in the neurofibromatosis 2 gene occurs in patients with mild and severe phenotypes.
Scoles DR, et al.
Neurology 47 : 544-546. 1996
91NF2
Germ-line mutations in the neurofibromatosis 2 gene : correlations with disease severity and retinal abnormalities.
Parry DM, et al.
Am J Hum Genet 59 : 529-539. 1996
92NF2, SCWT
Schwannomatosis: a clinical and pathologic study.
MacCollin M, et al.
Neurology 46(4):1072-9. Review. 1996
93NF2, TSG22A
High frequency of nonsense mutations in the NF2 gene caused by C to T transitions in five CGA codons.
Sainz J, et al.
Hum Mol Genet 4 : 137-139. 1995
94NF2, TSG22A
Somatic mutations in the neurofibromatosis type 2 gene in sporadic meningiomas.
Papi L, et al.
Hum Genet 95 : 347-351. 1995
95TSG22A, NF2
High frequency of inactivating mutations in the neurofibromatosis type 2gene (NF2) in primary malignant mesotheliomas.
Bianchi AB, et al.
Proc Natl Acad Sci U S A 92 : 10854-10858. 1995
96NF2
A 163-bp deletion at the C-terminus of the schwannomin gene associated with variable phenotypes of neurofibromatosis type 2.
Kluwe L, et al.
Hum Genet 95 : 443-446. 1995
97TSG22A, NF2
Analysis of the NF2 tumor-suppressor gene and of chromosome 22 deletions in gliomas.
Hoang-Xuan K, et al.
Int J Cancer 60 : 478-481. 1995
98NF2, TSG22A
Eleven novel mutations in the NF2 tumour suppressor gene.
Bourn D, et al.
Hum Genet 95 : 572-574. 1995
99NF2
Highly polymorphic dinucleotide repeat at the NF2 gene.
Bourn D, et al.
Hum Genet 95 : 712. 1995
100NF2
Family with neurofibromatosis type 2 and autosomal dominant hearing loss : identification of carriers of the mutated NF2 gene.
Bijlsma EK, et al.
Hum Genet 96 : 1-5. 1995
101NF2
Predominant occurence of somatic mutations of the NF2 gene in meningiomas and schwannomas.
MŽrel P, et al.
Genes Chromosomes Cancer 13 : 211-216. 1995
102TSG22A, NF2
Screening for germ-line mutations in the NF2 gene.
MŽrel P, et al.
Genes Chromosomes Cancer 12 : 117-127. 1995
103NF2, MGCR
Physical mapping of the NF2/meningioma region on human chromosome 22q12.
Ruttledge MH, et al.
Genomics 19 : 52-59. 1994
104NF2, TSG22A
Somatic NF2 gene mutations in familial and non-familial vestibular schwannoma.
Irving RM, et al.
Hum Mol Genet 3 : 347-350. 1994
105NF2, TSG22A
The neurofibromatosis type 2 gene is inactivated in schawnnomas.
Twist EC, et al.
Hum Mol Genet 3 : 147-151. 1994
106NF2, TSG22A
Exon scanning for mutation of the NF2 gene in schwannomas.
Jacoby LB, et al.
Hum Mol Genet 3 : 413-419. 1994
107NF2
The neurofibromatosis 2 (NF2) tumor suppressor gene encodes multiple alternatively spliced transcripts.
Pykett MJ, et al.
Hum Mol Genet 3 : 559-564. 1994
108NF2, TSG22A
Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers.
Arakawa H, et al.
Hum Mol Genet 3 : 565-568. 1994
109NF2, TSG22A
Germline mutations in the neurofibromatosis type 2 tumour suppressor gene.
Bourn D, et al.
Hum Mol Genet 3 : 813-816. 1994
110TSG22A, NF2
Mutations of the neurofibromatosis type 2 gene and lack of the gene product in vestibular schwannomas.
Sainz J, et al.
Hum Mol Genet 3 : 885-891. 1994
111TSG22A, NF2
Characterization of the translocation breakpoint on chromosome 22q12.2 in a patient with neurofibromatosis type 2 (NF2).
Arai E, et al.
Hum Mol Genet 3 : 937-939. 1994
112TSG22A, NF2
Frequent NF2 gene transcript mutations in sporadic meningiomas and vestibular schwannomas.
Lekanne Deprez RH, et al.
Am J Hum Genet 54 : 1022-1929. 1994
113NF2
Mutational analysis of patients with neurofibromatosis 2.
MacCollin M, et al.
Am J Hum Genet 55 : 314-320. 1994
114NF2
Analysis of mutations in the SCH gene in schwannomas.
Bijlsma EK, et al.
Genes Chromosomes Cancer 11 : 7-14. 1994
115NF2
Dinucleotide repeat polymorphism at the NF2 gene.
Bourn D, et al.
Hum Mol Genet 3 : 1914. 1994
116NF2
An anti-ras function of neurofibromatosis type 2 gene product (NF2/Merlin).
Tikoo A, et al.
J Biol Chem 269 : 23387-23390. 1994
117NF2, TSG22A
A mutation in the neurofibromatosis type 2 tumor-suppressor gene, giving rise to widely different clinical phenotypes in two unrelated individuals.
Bourn D, et al.
Am J Hum Genet 55 : 69-73. 1994
118NF2
A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor.
Trofatter JA, et al.
Cell 72 : 791-800. 1993
119TSG22A, NF2
Molecular genetic analysis of the mechanism of tumorigenesis in acoustic neuroma.
Irving RM, et al.
Arch Otolaryngol Head Neck Surg 119 : 1222-1228. 1993
120NF2
Familial meningioma is not allelic to neurofibromatosis 2.
Pulst SM, et al.
Neurology 43 : 2096-2098. 1993
121LIF, NF2
Mapping the breakpoint of a constitutional translocation on chromosome 22 in a patient with NF2.
Arai E, et al.
Genes Chromosomes Cancer 6 : 235-238. 1993
122NF2
A disease-associated germline deletion maps the type 2 neurofibromatosis (NF2) gene between the Ewing sarcoma region and the leukemia inhibitory factor locus.
Watson CJ, et al.
Hum Mol Genet 2 : 701-704. 1993
123NF2
Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2.
Rouleau GA, et al.
Nature 363 : 515-521. 1993
124NF2
Germline deletion in a neurofibromatosis type 2 kindred inactivates the NF2 gene and a candidate meningioma locus.
Sanson M, et al.
Hum Mol Genet 2 : 1215-1220. 1993
125NF2, TSG22A
Analysis of chromosome 22 deletions in neurofibromatosis type 2-related tumors.
Wolff RK, et al.
Am J Hum Genet 51 : 478-485. 1992
126NF2
Neurofibromatosis type 2 appears to be a genetically homogeneous disease.
Narod SA, et al.
Am J Hum Genet 51 : 486-496. 1992
127NF2
Constitutional translocation t(4;22)(q12;q12.2) associated with neurofibromatosis type 2.
Arai E, et al.
Am J Med Genet 44 : 163-167. 1992
128NF2
A radiation hybrid map of the region on human chromosome 22 containing the neurofibromatosis type 2 locus.
Frazer KA, et al.
Genomics 14 : 574-584. 1992
129NF2
Ring chromosome 22 and neurofibromatosis.
Tommerup N, et al.
Clin Genet 42 : 171-177. 1992
130EPB41, MSN, NF2, PTPN13, PTPN3, RDX, TLN1, EZR
A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites.
Sato N, et al.
J Cell Sci 103 : 131-143. 1992
131NF2
Loss of chromosome 22 alleles in human sporadic spinal schwannomas.
Fontaine B, et al.
Ann Neurol 29 : 183-186. 1991
132NF2
Flanking markers bracket the neurofibromatosis type 2 (NF2) gene on chromosome 22.
Rouleau GA, et al.
Am J Hum Genet 46 : 323-328. 1990
133NF2
Cytogenetic and in situ DNA-hybridization studies in intracranial tumors of a patient with central neurofibromatosis.
Wullich B, Kiechle-Schwarz M, Mayfrank L, Schempp W.
Hum Genet 82 : 31-34. 1989
134NF2
Neurofibromatosis 2 : Clinical and DNA linkage studies of a large kindred.
Wertelecki W, et al.
N Engl J Med 319 : 278-283. 1988
135NF2, D22S1, D22S9
Common pathogenic mechanism for three tumor types in bilateral acoustic neurobibromatosis.
Seizinger BR, et al.
Science 236 : 317-319. 1987
136NF2
Genetic linkage of bilateral acoustic neurofibromatosis to a DNA marker on chromosome 22.
Rouleau GA, et al.
Nature 329 : 246-248. 1987
137NF2
Loss of genes on chromosome 22 in tumorigenesis of human acoustic neuroma.
Seizinger BR, et al.
Nature 322 : 644-647. 1986