| 1 | DIAR4, NEUROG3
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| A novel NEUROG3 mutation in neonatal diabetes associated with a neuro-intestinal syndrome.
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| Hancili S, Bonnefond A, Philippe J, Vaillant E, De Graeve F, Sand O, Busiah K, Robert JJ, Polak M, Froguel P, Güven A, Vaxillaire M.
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| Pediatr Diabetes ediatr Diabetes. 2017 Sep 22. doi: 10.1111/pedi.12576. [Epub ahead of print]
2017
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| 2 | NEUROG3
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| Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation.
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| Azzarelli R, Hurley C, Sznurkowska MK, Rulands S, Hardwick L, Gamper I, Ali F, McCracken L, Hindley C, McDuff F, Nestorowa S, Kemp R, Jones K, Göttgens B, Huch M, Evan G, Simons BD, Winton D, Philpott A.
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| Dev Cell 41(3):274-286.e5. doi: 10.1016/j.devcel.2017.04.004. Epub 2017 Apr 27.
2017
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| 3 | NEUROG3
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| Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors.
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| Krentz NAJ, van Hoof D, Li Z, Watanabe A, Tang M, Nian C, German MS, Lynn FC.
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| Dev Cell 41(2):129-142.e6. doi: 10.1016/j.devcel.2017.02.006.
2017
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| 4 | NEUROG3, PAX6, PDX1
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| Pdxl and its role in activating Ngn3 and Pax6 to induce differentiation of iPSCs into islet β cells.
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| Qin Y, Xiao L, Zhan XB, Zhou HX.
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| Genet Mol Res 14(3):8892-900. doi: 10.4238/2015.August.3.12.
2015
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| 5 | NEUROG3
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| Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate.
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| Gomez DL, O'Driscoll M, Sheets TP, Hruban RH, Oberholzer J, McGarrigle JJ, Shamblott MJ.
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| PLoS One 10(8):e0133862. doi: 10.1371/journal.pone.0133862. eCollection 2015.
2015
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| 6 | NEUROG3
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| Neurogenin3 restricts serotonergic neuron differentiation to the hindbrain.
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| Carcagno AL, Di Bella DJ, Goulding M, Guillemot F, Lanuza GM.
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| J Neurosci 34(46):15223-33. doi: 10.1523/JNEUROSCI.3403-14.2014. Erratum in: J Neurosci. 2015 May 20;35(20):8037.
2014
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| 7 | NEUROG3
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| Neurogenin 3 is important but not essential for pancreatic islet development in humans.
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| Rubio-Cabezas O, Codner E, Flanagan SE, Gómez JL, Ellard S, Hattersley AT.
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| Diabetologia 57(11):2421-4. doi: 10.1007/s00125-014-3349-y. Epub 2014 Aug 14. No abstract available.
2014
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| 8 | FOXA2, NEUROG3
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| Neurogenin3 cooperates with Foxa2 to autoactivate its own expression.
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| Ejarque M, Cervantes S, Pujadas G, Tutusaus A, Sanchez L, Gasa R.
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| J Biol Chem 288(17):11705-17. doi: 10.1074/jbc.M112.388173. Epub 2013 Mar 7.
2013
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| 9 | NEUROG3
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| A CRM1-mediated nuclear export signal is essential for cytoplasmic localization of neurogenin 3 in neurons.
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| Simon-Areces J, Acaz-Fonseca E, Ruiz-Palmero I, Garcia-Segura LM, Arevalo MA.
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| PLoS One 8(1):e55237. doi: 10.1371/journal.pone.0055237. Epub 2013 Jan 30.
2013
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| 10 | MAFA, NEUROG3, PDX1
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| Reprogramming of various cell types to a beta-like state by Pdx1, Ngn3 and MafA.
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| Akinci E, Banga A, Tungatt K, Segal J, Eberhard D, Dutton JR, Slack JM.
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| PLoS One 8(11):e82424. doi: 10.1371/journal.pone.0082424. eCollection 2013.
2013
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| 11 | NEUROG3
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| A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation.
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| Shih HP, Kopp JL, Sandhu M, Dubois CL, Seymour PA, Grapin-Botton A, Sander M.
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| Development 139(14):2488-99. doi: 10.1242/dev.078634. Epub 2012 Jun 6.
2012
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| 12 | CCAR1, NEUROG3
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| CCAR1 is required for Ngn3-mediated endocrine differentiation.
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| Lu CK, Lai YC, Lin YF, Chen HR, Chiang MK.
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| Biochem Biophys Res Commun 418(2):307-12. doi: 10.1016/j.bbrc.2012.01.016. Epub 2012 Jan 12.
2012
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| 13 | GLIS3, NEUROG3, ONECUT1
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| Glis3 regulates neurogenin 3 expression in pancreatic β-cells and interacts with its activator, Hnf6.
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| Kim YS, Kang HS, Takeda Y, Hom L, Song HY, Jensen J, Jetten AM.
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| Mol Cells 34(2):193-200. doi: 10.1007/s10059-012-0109-z. Epub 2012 Jul 20.
2012
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| 14 | NEUROG3
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| NEUROG3 is a critical downstream effector for STAT3-regulated differentiation of mammalian stem and progenitor spermatogonia.
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| Kaucher AV, Oatley MJ, Oatley JM.
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| Biol Reprod 86(5):164, 1-11. doi: 10.1095/biolreprod.111.097386. Print 2012 May.
2012
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| 15 | CDKN1A, NEUROG3
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| Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.
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| Miyatsuka T, Kosaka Y, Kim H, German MS.
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| Proc Natl Acad Sci U S A 108(1):185-90. Epub 2010 Dec 20.
2011
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| 16 | ASCL1, NEUROG3
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| Differential requirements for neurogenin 3 in the development of POMC and NPY neurons in the hypothalamus.
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| Pelling M, Anthwal N, McNay D, Gradwohl G, Leiter AB, Guillemot F, Ang SL.
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| Dev Biol 349(2):406-16. Epub 2010 Nov 11.
2011
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| 17 | NEUROG3
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| Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium.
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| Magenheim J, Klein AM, Stanger BZ, Ashery-Padan R, Sosa-Pineda B, Gu G, Dor Y.
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| Dev Biol 359(1):26-36. doi: 10.1016/j.ydbio.2011.08.006. Epub 2011 Aug 17.
2011
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| 18 | INSM2, NEUROD1, NEUROG3
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| Expression of insulinoma-associated 2 (INSM2) in pancreatic islet cells is regulated by the transcription factors Ngn3 and NeuroD1.
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| Cai T, Chen X, Wang R, Xu H, You Y, Zhang T, Lan MS, Notkins AL.
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| Endocrinology 152(5):1961-9. doi: 10.1210/en.2010-1065. Epub 2011 Feb 22.
2011
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| 19 | MAFA, NEUROG3, PDX1
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| TAT-mediated transduction of MafA protein in utero results in enhanced pancreatic insulin expression and changes in islet morphology.
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| Vargas N, Álvarez-Cubela S, Giraldo JA, Nieto M, Fort NM, Cechin S, García E, Espino-Grosso P, Fraker CA, Ricordi C, Inverardi L, Pastori RL, Domínguez-Bendala J.
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| PLoS One 6(8):e22364. doi: 10.1371/journal.pone.0022364. Epub 2011 Aug 4.
2011
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| 20 | NEUROG3, OVOL1
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| OVO homologue-like 1 (Ovol1) transcription factor: a novel target of neurogenin-3 in rodent pancreas.
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| Vetere A, Li WC, Paroni F, Juhl K, Guo L, Nishimura W, Dai X, Bonner-Weir S, Sharma A.
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| Diabetologia 53(1):115-22. Epub 2009 Oct 31.PMID: 19882138 2010
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| 21 | NEUROG3, PHIG, RFX6
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| Rfx6 directs islet formation and insulin production in mice and humans.
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| Smith SB, Qu HQ, Taleb N, Kishimoto NY, Scheel DW, Lu Y, Patch AM, Grabs R, Wang J, Lynn FC, Miyatsuka T, Mitchell J, Seerke R, Désir J, Eijnden SV, Abramowicz M, Kacet N, Weill J, Renard ME, Gentile M, Hansen I, Dewar K, Hattersley AT, Wang R, Wilson ME, Johnson JD, Polychronakos C, German MS.
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| Nature 463(7282):775-80. 2010
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| 22 | NEUROD1, NEUROG3
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| Neurogenin 3 and neurogenic differentiation 1 are retained in the cytoplasm of multiple endocrine neoplasia type 1 islet and pancreatic endocrine tumor cells.
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| Lejonklou MH, Edfeldt K, Johansson TA, Stalberg P, Skogseid B.
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| Pancreas 38(3):259-66. 2009
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| 23 | NEUROG3, ONECUT1
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| Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation.
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| Zhang H, Ables ET, Pope CF, Washington MK, Hipkens S, Means AL, Path G, Seufert J, Costa RH, Leiter AB, Magnuson MA, Gannon M.
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| Mech Dev 126(11-12):958-73. doi: 10.1016/j.mod.2009.09.006. Epub 2009 Sep 18.
2009
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| 24 | NEUROG3
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| Genetic variation of Neurogenin 3 is slightly associated with hyperproinsulinaemia and progression toward type 2 diabetes.
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| Li J, Bergmann A, Reimann M, Schulze J, Bornstein SR, Schwarz PE.
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| Exp Clin Endocrinol Diabetes 116(3):178-83. Epub 2007 Oct 12.PMID: 18072012 2008
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| 25 | NEUROG1, NEUROG2, NEUROG3, NEUROD1, NEUROD4
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| Neurogenin and NeuroD direct transcriptional targets and their regulatory enhancers.
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| Seo S, Lim JW, Yellajoshyula D, Chang LW, Kroll KL.
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| EMBO J 26(24):5093-108. Epub 2007 Nov 15. 2007
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| 26 | DIAR4, NEUROG3
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| Mutant neurogenin-3 in congenital malabsorptive diarrhea.
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| Wang J, Cortina G, Wu SV, Tran R, Cho JH, Tsai MJ, Bailey TJ, Jamrich M, Ament ME, Treem WR, Hill ID, Vargas JH, Gershman G, Farmer DG, Reyen L, Martin MG.
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| N Engl J Med 355(3):270-80. 2006
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| 27 | NEUROG3
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| NEUROG3 variants and type 2 diabetes in Italians.
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| Milord E, Gragnoli C.
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| Minerva Med 97(5):373-8.PMID: 17146417 2006
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| 28 | NEUROG3
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| Polymorphisms in the neurogenin 3 gene (NEUROG) and their relation to altered insulin secretion and diabetes in the Danish Caucasian population.
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| Jensen JN, Hansen L, Ekstrom CT, Pociot F, Nerup J, Hansen T, Pedersen O.
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| Diabetologia 44(1):123-6. 2001
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| 29 | NEUROG3
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| neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas.
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| Gradwohl G, Dierich A, LeMeur M, Guillemot F.
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| Proc Natl Acad Sci U S A 97(4):1607-11. 2000
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| 30 | NEUROD1, NEUROG3
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| Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.
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| Huang HP, Liu M, El-Hodiri HM, Chu K, Jamrich M, Tsai MJ.
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| Mol Cell Biol 20(9):3292-307. 2000
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| 31 | NEO1, NEUROG3
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| neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS.
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| Sommer L, Ma Q, Anderson DJ.
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| Mol Cell Neurosci 8(4):221-41. Review. 1996
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