Citations for
1NEU1, NEU3
Identification of lysosomal sialidase NEU1 and plasma membrane sialidase NEU3 in human erythrocytes.
D'Avila F, Tringali C, Papini N, Anastasia L, Croci G, Massaccesi L, Monti E, Tettamanti G, Venerando B.
J Cell Biochem 114(1):204-11. doi: 10.1002/jcb.24355. 2013
2NEU1, NEU3
NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not.
Cross AS, Hyun SW, Miranda-Ribera A, Feng C, Liu A, Nguyen C, Zhang L, Luzina IG, Atamas SP, Twaddell WS, Guang W, Lillehoj EP, Puché AC, Huang W, Wang LX, Passaniti A, Goldblum SE.
J Biol Chem 287(19):15966-80. Epub 2012 Mar 8. 2012
3NEU1, NEU2, NEU3, NEU4
Mammalian sialidases: physiological and pathological roles in cellular functions.
Miyagi T, Yamaguchi K.
Glycobiology 22(7):880-96. Epub 2012 Feb 28. Review. 2012
4NEU1
NEU1 sialidase expressed in human airway epithelia regulates epidermal growth factor receptor (EGFR) and MUC1 protein signaling.
Lillehoj EP, Hyun SW, Feng C, Zhang L, Liu A, Guang W, Nguyen C, Luzina IG, Atamas SP, Passaniti A, Twaddell WS, Puché AC, Wang LX, Cross AS, Goldblum SE.
J Biol Chem 287(11):8214-31. Epub 2012 Jan 13. 2012
5NEU1, NEU3
Sialidases on mammalian sperm mediate deciduous sialylation during capacitation.
Ma F, Wu D, Deng L, Secrest P, Zhao J, Varki N, Lindheim S, Gagneux P.
J Biol Chem 287(45):38073-9. doi: 10.1074/jbc.M112.380584. Epub 2012 Sep 18. 2012
6MMP9, NEU1
Neu1 sialidase and matrix metalloproteinase-9 cross-talk is essential for Toll-like receptor activation and cellular signaling.
Abdulkhalek S, Amith SR, Franchuk SL, Jayanth P, Guo M, Finlay T, Gilmour A, Guzzo C, Gee K, Beyaert R, Szewczuk MR.
J Biol Chem 286(42):36532-49. doi: 10.1074/jbc.M111.237578. Epub 2011 Aug 26. 2011
7NEU1
Detection of Neu1 sialidase activity in regulating Toll-like receptor activation.
Amith SR, Jayanth P, Finlay T, Franchuk S, Gilmour A, Abdulkhalek S, Szewczuk MR.
J Vis Exp (43). doi:pii: 2142. 10.3791/2142. 2010
8CTSA, NEU1
Heterodimerization of the sialidase NEU1 with the chaperone protective protein/cathepsin A prevents its premature oligomerization.
Bonten EJ, Campos Y, Zaitsev V, Nourse A, Waddell B, Lewis W, Taylor G, d'Azzo A.
J Biol Chem 284(41):28430-41. Epub 2009 Aug 7. 2009
9NEU1, NEU3
Sialidase occurs in both membranes of the nuclear envelope and hydrolyzes endogenous GD1a.
Wang J, Wu G, Miyagi T, Lu ZH, Ledeen RW.
J Neurochem 111(2):547-54. Epub 2009 Aug 17.PMID: 19686243 2009
10NEU1
Neuraminidase-1, a subunit of the cell surface elastin receptor, desialylates and functionally inactivates adjacent receptors interacting with the mitogenic growth factors PDGF-BB and IGF-2.
Hinek A, Bodnaruk TD, Bunda S, Wang Y, Liu K.
Am J Pathol 173(4):1042-56. Epub 2008 Sep 4. 2008
11NEU1
Neuraminidase 1 is a negative regulator of lysosomal exocytosis.
Yogalingam G, Bonten EJ, van de Vlekkert D, Hu H, Moshiach S, Connell SA, d'Azzo A.
Dev Cell 15(1):74-86. 2008
12NEU1, NEU2, NEU3
NEU3 sialidase strictly modulates GM3 levels in skeletal myoblasts C2C12 thus favoring their differentiation and protecting them from apoptosis.
Anastasia L, Papini N, Colazzo F, Palazzolo G, Tringali C, Dileo L, Piccoli M, Conforti E, Sitzia C, Monti E, Sampaolesi M, Tettamanti G, Venerando B.
J Biol Chem 283(52):36265-71. Epub 2008 Oct 22. 2008
13NEU1
Lysosomal sialidase (neuraminidase-1) is targeted to the cell surface in a multiprotein complex that facilitates elastic fiber assembly.
Hinek A, Pshezhetsky AV, von Itzstein M, Starcher B.
J Biol Chem 281(6):3698-710. Epub 2005 Nov 28. 2006
14NEU1, NEU1D
Five novel mutations in the lysosomal sialidase gene (NEU1) in type II sialidosis patients and assessment of their impact on enzyme activity and intracellular targeting using adenovirus-mediated expression.
Pattison S, Pankarican M, Rupar CA, Graham FL, Igdoura SA.
Hum Mutat 23(1):32-9. 2004
15NEU1, NEU1D
Molecular pathology of NEU1 gene in sialidosis.
Seyrantepe V, Poupetova H, Froissart R, Zabot MT, Maire I, Pshezhetsky AV.
Hum Mutat 22(5):343-52. 2003
16NEU1, NEU1D
Novel missense mutations in the human lysosomal sialidase gene in sialidosis patients and prediction of structural alterations of mutant enzymes.
Itoh K, Naganawa Y, Matsuzawa F, Aikawa S, Doi H, Sasagasako N, Yamada T, Kira J, Kobayashi T, Pshezhetsky AV, Sakuraba H.
J Hum Genet 47(1):29-37. 2002
17NEU1, NEU1D
Characterization of the sialidase molecular defects in sialidosis patients suggests the structural organization of the lysosomal multienzyme complex.
Lukong KE, Elsliger MA, Chang Y, Richard C, Thomas G, Carey W, Tylki-Szymanska A, Czartoryska B, Buchholz T, Criado GR, Palmeri S, Pshezhetsky AV.
Hum Mol Genet 9(7):1075-85. 2000
18NEU1, NEU1D
Novel mutations in lysosomal neuraminidase identify functional domains and determine clinical severity in sialidosis.
Bonten EJ, Arts WF, Beck M, Covanis A, Donati MA, Parini R, Zammarchi E, d'Azzo A.
Hum Mol Genet 9(18):2715-25. 2000
19NEU1, NEU1D
Molecular and structural studies of Japanese patients with sialidosis type 1.
Naganawa Y, Itoh K, Shimmoto M, Takiguchi K, Doi H, Nishizawa Y, Kobayashi T, Kamei S, Lukong KE, Pshezhetsky AV, Sakuraba H.
J Hum Genet 45(4):241-9. 2000
20CTSA, NEU1
Transport of human lysosomal neuraminidase to mature lysosomes requires protective protein/cathepsin A.
van der Spoel A, Bonten E, d'Azzo A.
EMBO J 17(6):1588-97. 1998
21NEU1, NEU1D
Cloning, expression and chromosomal mapping of human lysosomal sialidase and characterization of mutations in sialidosis.
Pshezhetsky AV, et al.
Nat Genet 15 : 316-320. 1997
22NEU1
Identification of a sialidase encoded in the human major histocompatibility complex.
Milner CM, et al.
J Biol Chem 272 : 4549-4558. 1997
23NEU1, NEU1D
Characterization of human lysosomal neuraminidase defines the molecular basis of the metabolic storage disorder sialidosis.
Bonten E, et al.
Genes Dev 10 : 3156-3169. 1996
24NEU1
Exclusion map of the gene for neuraminidase from 10(pter-p15.1).
Takano T, et al.
Clin Genet 43 : 166-167. 1993
25NEU1, NEU2
Molecular cloning and expression of cDNA encoding rat skeletal muscle cytosolic sialidase.
Miyagi T, et al.
J Biol Chem 268(35):26435-40. 1993
26NEU1
The patient with combined deficiency of neuraminidase and 21-hydroxylase.
Harada F, et al.
Hum Genet 75 : 91-92. 1987
27NEU1, GSL, CTSA
Sialidosis and galactosialidosis: chromosomal assignment of two genes associated with neuraminidase-deficiency disorders.
Mueller OT, et al.
Proc Natl Acad Sci U S A 83 : 1817-1821. 1986
28NEU1
Additional evidence for the location of the alpha-neuraminidase gene on chromosome 6.
Oohira T, et al.
Jpn J Hum Genet 31 : 309-310. 1986
29NEU1
The infantile form of sialidosis type II associated with congenital adrenal hyperplasia. Possible linkage between HLA and the neuraminidase deficiency gene.
Oohira T, et al.
Hum Genet 70 : 341-343. 1985
30NEU1
Neuraminidase deficiency presenting as non-immune hydrops fetalis.
Beck M, et al.
Eur J Pediatr 143 : 135-139. 1984
31NEU1
Genetic heterogeneity in human neuraminidase deficiency.
Hoogeveen AT, et al.
Nature 285 : 500-502. 1980
32NEU1
Sialidosis : a review of human neuraminidase deficiency.
Lowden JA, et al.
Am J Hum Genet 31 : 1-18. 1979
33NEU1
Sialidase (alpha-N-acetyl neuraminidase) deficiency : the enzyme defect in an adult with macular cherry-red spots and myoclonus without dementia.
Thomas GH, et al.
Clin Genet 13 : 369-379. 1978