1 | NELL1
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| Oligomerization-induced Conformational Change in the C-terminal Region of NELL1 Is Necessary for the Efficient Mediation of Murine MC3T3-E1 Cell Adhesion and Spreading.
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| Nakamura Y, Hasebe A, Takahashi K, Iijima M, Yoshimoto N, Maturana AD, Ting K, Kuroda S, Niimi T.
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| J Biol Chem Biol Chem. 2014 Feb 21. [Epub ahead of print]
2014
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2 | NELL1
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| Human NELL1 Protein Augments Constructive Tissue Remodeling with Biologic Scaffolds.
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| Turner NJ, Londono R, Dearth CL, Culiat CT, Badylak SF.
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| Cells Tissues Organs 198(4):249-65. doi: 10.1159/000356491. Epub 2013 Dec 7.
2013
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3 | NELL1
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| Expression and localization of Nell-1 during murine molar development.
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| Tang R, Wang Q, Du J, Yang P, Wang X.
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| J Mol Histol 44(2):175-81. doi: 10.1007/s10735-012-9472-5. Epub 2012 Dec 21.
2013
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4 | NELL1, NELL2
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| Structure-function analysis of Nel, a thrombospondin-1-like glycoprotein involved in neural development and functions.
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| Nakamura R, Nakamoto C, Obama H, Durward E, Nakamoto M.
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| J Biol Chem 287(5):3282-91. doi: 10.1074/jbc.M111.281485. Epub 2011 Dec 8.
2012
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5 | NELL1
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| Perivascular stem cells: a prospectively purified mesenchymal stem cell population for bone tissue engineering.
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| James AW, Zara JN, Zhang X, Askarinam A, Goyal R, Chiang M, Yuan W, Chang L, Corselli M, Shen J, Pang S, Stoker D, Wu B, Ting K, Péault B, Soo C.
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| Stem Cells Transl Med 1(6):510-9. doi: 10.5966/sctm.2012-0002. Epub 2012 Jun 11.
2012
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6 | ITGB1, NELL1
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| NELL-1 promotes cell adhesion and differentiation via Integrinβ1.
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| Shen J, James AW, Chung J, Lee K, Zhang JB, Ho S, Lee KS, Kim TM, Niimi T, Kuroda S, Ting K, Soo C.
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| J Cell Biochem 113(12):3620-8. doi: 10.1002/jcb.24253.
2012
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7 | NELL1, SLC20A1, SLC20A2
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| NELL-1 increases pre-osteoblast mineralization using both phosphate transporter Pit1 and Pit2.
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| Cowan CM, Zhang X, James AW, Kim TM, Sun N, Wu B, Ting K, Soo C.
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| Biochem Biophys Res Commun 422(3):351-7. doi: 10.1016/j.bbrc.2012.04.077. Epub 2012 May 3.
2012
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8 | NELL1, RUNX2, SOX9
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| Calvarial cleidocraniodysplasia-like defects with ENU-induced Nell-1 deficiency.
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| Zhang X, Ting K, Pathmanathan D, Ko T, Chen W, Chen F, Lee H, James AW, Siu RK, Shen J, Culiat CT, Soo C.
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| J Craniofac Surg 23(1):61-6. doi: 10.1097/SCS.0b013e318240c8c4.
2012
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9 | NELL1, NFATC2
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| Nfatc2 is a primary response gene of Nell-1 regulating chondrogenesis in ATDC5 cells.
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| Chen W, Zhang X, Siu RK, Chen F, Shen J, Zara JN, Culiat CT, Tetradis S, Ting K, Soo C.
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| J Bone Miner Res 26(6):1230-41. doi: 10.1002/jbmr.314.
2011
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10 | NELL1
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| A new function of Nell-1 protein in repressing adipogenic differentiation.
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| James AW, Pan A, Chiang M, Zara JN, Zhang X, Ting K, Soo C.
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| Biochem Biophys Res Commun 411(1):126-31. Epub 2011 Jun 23.
2011
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11 | APR3, NELL1
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| NELL-1 binds to APR3 affecting human osteoblast proliferation and differentiation.
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| Zou X, Shen J, Chen F, Ting K, Zheng Z, Pang S, Zara JN, Adams JS, Soo C, Zhang X.
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| FEBS Lett 585(15):2410-8. Epub 2011 Jun 26.
2011
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12 | NELL1, SP7
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| NELL-1, an osteoinductive factor, is a direct transcriptional target of Osterix.
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| Chen F, Zhang X, Sun S, Zara JN, Zou X, Chiu R, Culiat CT, Ting K, Soo C.
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| PLoS One 6(9):e24638. doi: 10.1371/journal.pone.0024638. Epub 2011 Sep 13.
2011
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13 | BMP2, NELL1
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| The effect of NELL1 and bone morphogenetic protein-2 on calvarial bone regeneration.
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| Aghaloo T, Cowan CM, Zhang X, Freymiller E, Soo C, Wu B, Ting K, Zhang Z.
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| J Oral Maxillofac Surg 68(2):300-8.PMID: 20116699 2010
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14 | NELL1, RUNX2
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| Involvement of MAPK signaling molecules and Runx2 in the NELL1-induced osteoblastic differentiation.
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| Bokui N, Otani T, Igarashi K, Kaku J, Oda M, Nagaoka T, Seno M, Tatematsu K, Okajima T, Matsuzaki T, Ting K, Tanizawa K, Kuroda S.
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| FEBS Lett 582(2):365-71. Epub 2007 Dec 17.PMID: 18082140 2008
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15 | NELL1, RUNX2
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| Craniosynostosis-associated gene nell-1 is regulated by runx2.
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| Truong T, Zhang X, Pathmanathan D, Soo C, Ting K.
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| J Bone Miner Res 22(1):7-18. 2007
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16 | NELL1
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| Hypermethylation of the nel-like 1 gene is a common and early event and is associated with poor prognosis in early-stage esophageal adenocarcinoma.
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| Jin Z, Mori Y, Yang J, Sato F, Ito T, Cheng Y, Paun B, Hamilton JP, Kan T, Olaru A, David S, Agarwal R, Abraham JM, Beer D, Montgomery E, Meltzer SJ.
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| Oncogene 26(43):6332-40. Epub 2007 Apr 23.PMID: 17452981 2007
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17 | NELL1
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| Nell-1 induced bone formation within the distracted intermaxillary suture.
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| Cowan CM, Cheng S, Ting K, Soo C, Walder B, Wu B, Kuroda S, Zhang X.
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| Bone 38(1):48-58. Epub 2005 Oct 20.PMID: 16243593 2006
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18 | NELL1
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| Overexpression of Nell-1, a craniosynostosis-associated gene, induces apoptosis in osteoblasts during craniofacial development.
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| Zhang X, Carpenter D, Bokui N, Soo C, Miao S, Truong T, Wu B, Chen I, Vastardis H, Tanizawa K, Kuroda S, Ting K.
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| J Bone Miner Res 18(12):2126-34. 2003
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19 | NELL1, NELL2
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| Brain specific human genes, NELL1 and NELL2, are predominantly expressed in neuroblastoma and other embryonal neuroepithelial tumors.
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| Maeda K, Matsuhashi S, Tabuchi K, Watanabe T, Katagiri T, Oyasu M, Saito N, Kuroda S.
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| Neurol Med Chir (Tokyo) 41(12):582-8; discussion 589.PMID: 11803583 2001
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20 | NELL1
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| Human NELL-1 expressed in unilateral coronal synostosis.
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| Ting K, et al.
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| J Bone Miner Res 14(1):80-9. 1999
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21 | NELL1, NELL2
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| The neuronal EGF-related genes NELL1 and NELL2 are expressed in hemopoietic cells and developmentally regulated in the B lineage.
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| Luce MJ, et al.
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| Gene 231(1-2):121-6. 1999
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22 | NELL1, NELL2
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| Biochemical characterization and expression analysis of neural thrombospondin-1-like proteins NELL1 and NELL2.
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| Kuroda S, Oyasu M, Kawakami M, Kanayama N, Tanizawa K, Saito N, Abe T, Matsuhashi S, Ting K.
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| Biochem Biophys Res Commun 265(1):79-86 1999
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23 | NELL1, PRKCB
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| Involvement of epidermal growth factor-like domain of NELL proteins in the novel protein-protein interaction with protein kinase C.
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| Kuroda S, Tanizawa K.
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| Biochem Biophys Res Commun 265(3):752-7. 1999
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24 | NELL1, NELL2
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| Cloning and characterization of two novel human cDNAs (NELL1 and NELL2) encoding proteins with six EGF-like repeats.
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| Watanabe TK, et al.
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| Genomics 38 : 273-276. 1996
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