Citations for
1C2CD5, CDK5, NDEL1, YWHAE
Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528.
Chapman DE, Reddy BJN, Huy B, Bovyn MJ, Cruz SJS, Al-Shammari ZM, Han H, Wang W, Smith DS, Gross SP.
Nat Commun 10(1):228. doi: 10.1038/s41467-018-08110-z. 2019
2CAMK1D, CCDC25, GABRG3, MAGI2, NDEL1
Genome-wide investigation of schizophrenia associated plasma Ndel1 enzyme activity.
Gadelha A, Coleman J, Breen G, Mazzoti DR, Yonamine CM, Pellegrino R, Ota VK, Belangero SI, Glessner J, Sleiman P, Hakonarson H, Hayashi MA, Bressan RA.
Schizophr Res 172(1-3):60-7. doi: 10.1016/j.schres.2016.01.043. 2016
3DEF8, FAM98A, NDEL1, PLEKHM1
PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis
Fujiwara T, Ye S, Castro-Gomes T, Winchell CG, Andrews NW, Voth DE, Varughese KI, Mackintosh SG, Feng Y, Pavlos N, Nakamura T, Manolagas SC, Zhao H.
JCI Insight. Oct 20;1(17):e86330. doi: 10.1172/jci.insight.86330. 2016
4NDE1, NDEL1
The expression and roles of Nde1 and Ndel1 in the adult mammalian central nervous system.
Pei Z, Lang B, Fragoso YD, Shearer KD, Zhao L, Mccaffery PJ, Shen S, Ding YQ, McCaig CD, Collinson JM.
Neuroscience 271:119-36. doi: 10.1016/j.neuroscience.2014.04.031. Epub 2014 Apr 29. 2014
5NDEL1, PAFAH1B1
LIS1 controls mitosis and mitotic spindle organization via the LIS1-NDEL1-dynein complex.
Moon HM, Youn YH, Pemble H, Yingling J, Wittmann T, Wynshaw-Boris A.
Hum Mol Genet 23(2):449-66. doi: 10.1093/hmg/ddt436. Epub 2013 Sep 12. 2014
6NDEL1, UBR4
p600 regulates spindle orientation in apical neural progenitors and contributes to neurogenesis in the developing neocortex.
Belzil C, Asada N, Ishiguro K, Nakaya T, Parsons K, Pendolino V, Neumayer G, Mapelli M, Nakatani Y, Sanada K, Nguyen MD.
Biol Open 3(6):475-85. doi: 10.1242/bio.20147807. 2014
7NDE1, NDEL1
NDE1 and NDEL1: twin neurodevelopmental proteins with similar 'nature' but different 'nurture'.
Bradshaw NJ, Hennah W, Soares DC.
Biomol Concepts 4(5):447-64. doi: 10.1515/bmc-2013-0023. 2013
8NDE1, NDEL1, PAFAH1B1
Nudel/NudE and Lis1 promote dynein and dynactin interaction in the context of spindle morphogenesis.
Wang S, Ketcham SA, Schön A, Goodman B, Wang Y, Yates J 3rd, Freire E, Schroer TA, Zheng Y.
Mol Biol Cell 24(22):3522-33. doi: 10.1091/mbc.E13-05-0283. Epub 2013 Sep 11. 2013
9NDEL1, NUDCD3, PAFAH1B1
Distinct functions of nuclear distribution proteins LIS1, Ndel1 and NudCL in regulating axonal mitochondrial transport.
Shao CY, Zhu J, Xie YJ, Wang Z, Wang YN, Wang Y, Su LD, Zhou L, Zhou TH, Shen Y.
Traffic 14(7):785-97. doi: 10.1111/tra.12070. Epub 2013 Apr 22. Erratum in: Traffic. 2013 Oct;14(10):1105-8. 2013
10NDE1, NDEL1
The mitosis and neurodevelopment proteins NDE1 and NDEL1 form dimers, tetramers, and polymers with a folded back structure in solution.
Soares DC, Bradshaw NJ, Zou J, Kennaway CK, Hamilton RS, Chen ZA, Wear MA, Blackburn EA, Bramham J, Böttcher B, Millar JK, Barlow PN, Walkinshaw MD, Rappsilber J, Porteous DJ.
J Biol Chem 287(39):32381-93. Epub 2012 Jul 27. 2012
11NDEL1
Nudel is crucial for the WAVE complex assembly in vivo by selectively promoting subcomplex stability and formation through direct interactions.
Wu S, Ma L, Wu Y, Zeng R, Zhu X.
Cell Res 22(8):1270-84. doi: 10.1038/cr.2012.47. Epub 2012 Mar 27. 2012
12NDEL1, PAFAH1B1
The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein.
Zyłkiewicz E, Kijańska M, Choi WC, Derewenda U, Derewenda ZS, Stukenberg PT.
J Cell Biol 192(3):433-45. Epub 2011 Jan 31. 2011
13CDK5, NDEL1, PAFAH1B1
A Cdk5-dependent switch regulates Lis1/Ndel1/dynein-driven organelle transport in adult axons.
Pandey JP, Smith DS.
J Neurosci 31(47):17207-19. doi: 10.1523/JNEUROSCI.4108-11.2011. 2011
14DISC1, NDEL1
Molecular characterization of disrupted in schizophrenia-1 risk variant S704C reveals the formation of altered oligomeric assembly.
Narayanan S, Arthanari H, Wolfe MS, Wagner G.
J Biol Chem 286(51):44266-76. doi: 10.1074/jbc.M111.271593. Epub 2011 Oct 13. 2011
15CIT, DISC1, FEZ1, NDE1, NDEL1, PAFAH1B1
Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging.
Nicodemus KK, Callicott JH, Higier RG, Luna A, Nixon DC, Lipska BK, Vakkalanka R, Giegling I, Rujescu D, Clair DS, Muglia P, Shugart YY, Weinberger DR.
Hum Genet um Genet. 2010 Jan 19. [Epub ahead of print] 2010
16LMNB1, LMNB2, NDEL1, NUDEL1
Requirement for Nudel and dynein for assembly of the lamin B spindle matrix.
Ma L, Tsai MY, Wang S, Lu B, Chen R, Iii JR, Zhu X, Zheng Y.
Nat Cell Biol 11(3):247-56. Epub 2009 Feb 8. 2009
17NDEL1, PAFAH1B1, PAFAH1B2, PAFAH1B3
Opposing effects of Ndel1 and alpha1 or alpha2 on cytoplasmic dynein through competitive binding to Lis1.
Ding C, Liang X, Ma L, Yuan X, Zhu X.
J Cell Sci 122(Pt 16):2820-7. Epub 2009 Jul 21. 2009
18DISC1, NDE1, NDEL1, SCZD12
Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding.
Burdick KE, Kamiya A, Hodgkinson CA, Lencz T, DeRosse P, Ishizuka K, Elashvili S, Arai H, Goldman D, Sawa A, Malhotra AK.
Hum Mol Genet 17(16):2462-73. Epub 2008 May 10. 2008
19NDEL1, PAFAH1B1
LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein.
Yamada M, Toba S, Yoshida Y, Haratani K, Mori D, Yano Y, Mimori-Kiyosue Y, Nakamura T, Itoh K, Fushiki S, Setou M, Wynshaw-Boris A, Torisawa T, Toyoshima YY, Hirotsune S.
EMBO J 27(19):2471-83. Epub 2008 Sep 11. 2008
20DISC1, NDE1, NDEL1, PAFAH1B1, PDE4B
DISC1, PDE4B, and NDE1 at the centrosome and synapse.
Bradshaw NJ, Ogawa F, Antolin-Fontes B, Chubb JE, Carlyle BC, Christie S, Claessens A, Porteous DJ, Millar JK.
Biochem Biophys Res Commun 377(4):1091-6. Epub 2008 Nov 5. 2008
21ARHGAP1, CDC42, NDEL1
Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells.
Shen Y, Li N, Wu S, Zhou Y, Shan Y, Zhang Q, Ding C, Yuan Q, Zhao F, Zeng R, Zhu X.
Dev Cell 14(3):342-53. 2008
22NDEL1, PPP4C
Protein phosphatase 4 catalytic subunit regulates Cdk1 activity and microtubule organization via NDEL1 dephosphorylation.
Toyo-oka K, Mori D, Yano Y, Shiota M, Iwao H, Goto H, Inagaki M, Hiraiwa N, Muramatsu M, Wynshaw-Boris A, Yoshiki A, Hirotsune S.
J Cell Biol 180(6):1133-47. Epub 2008 Mar 17.PMID: 18347064 2008
23NDEL1, DISC1
Disrupted-In-Schizophrenia 1 Regulates Integration of Newly Generated Neurons in the Adult Brain.
Duan X, Chang JH, Ge S, Faulkner RL, Kim JY, Kitabatake Y, Liu XB, Yang CH, Jordan JD, Ma DK, Liu CY, Ganesan S, Cheng HJ, Ming GL, Lu B, Song H.
Cell 130(6):1146-1158. Epub 2007 Sep 6. 2007
24MDS, NDEL1, PAFAH1B1, YWHAE
Lissencephaly and LIS1: insights into the molecular mechanisms of neuronal migration and development.
Wynshaw-Boris A.
Clin Genet 72(4):296-304. 2007
25CENPF, NDE1, NDEL1
Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes.
Vergnolle MA, Taylor SS.
Curr Biol 17(13):1173-9. 2007
26DISC1, PAFAH1B1, FEZ1, NDEL1
Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs.
Lipska BK, Peters T, Hyde TM, Halim N, Horowitz C, Mitkus S, Weickert CS, Matsumoto M, Sawa A, Straub RE, Vakkalanka R, Herman MM, Weinberger DR, Kleinman JE.
Hum Mol Genet 15(8):1245-58. Epub 2006 Mar 1. 2006
27DISC1, NDEL1
DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1.
Kamiya A, Tomoda T, Chang J, Takaki M, Zhan C, Morita M, Cascio MB, Elashvili S, Koizumi H, Takanezawa Y, Dickerson F, Yolken R, Arai H, Sawa A.
Hum Mol Genet 15(22):3313-23. Epub 2006 Oct 11. 2006
28KATNA1, KATNB1, LIS1, NDEL1
Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration.
Toyo-Oka K, Sasaki S, Yano Y, Mori D, Kobayashi T, Toyoshima YY, Tokuoka SM, Ishii S, Shimizu T, Muramatsu M, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S.
Hum Mol Genet 14(21):3113-28. Epub 2005 Oct 3. 2005
29DISC1, NDEL1
Subcellular targeting of DISC1 is dependent on a domain independent from the Nudel binding site.
Brandon NJ, Schurov I, Camargo LM, Handford EJ, Duran-Jimeniz B, Hunt P, Millar JK, Porteous DJ, Shearman MS, Whiting PJ.
Mol Cell Neurosci 28(4):613-24. 2005
30NDEL1
Cloning and characterization of the human and rabbit NUDEL-oligopeptidase promoters and their negative regulation.
Guerreiro JR, Winnischofer SM, Bastos MF, Portaro FC, Sogayar MC, de Camargo AC, Hayashi MA.
Biochim Biophys Acta 1730(1):77-84. 2005
31NDEL1, NDE1, PAFAH1B
Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality.
Sasaki S, Mori D, Toyo-oka K, Chen A, Garrett-Beal L, Muramatsu M, Miyagawa S, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S.
Mol Cell Biol 25(17):7812-27. 2005
32ARAP3, ATF4, DISC1, MAP1A, NDEL1, TRAF3IP1
DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.
Morris JA, Kandpal G, Ma L, Austin CP.
Hum Mol Genet 12(13):1591-608. 2003
33CDK5, LIS1, NDEL1, YWHAE
14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome.
Toyo-oka K, Shionoya A, Gambello MJ, Cardoso C, Leventer R, Ward HL, Ayala R, Tsai LH, Dobyns W, Ledbetter D, Hirotsune S, Wynshaw-Boris A.
Nat Genet 34(3):274-85. 2003
34CDK5, NDEL1, PAFAH1B1
NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein.
Niethammer M, Smith DS, Ayala R, Peng J, Ko J, Lee MS, Morabito M, TsaiLH.
Neuron 28(3):697-711. 2000