| 1 | IRF8, NAIP, NLRC4
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| IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
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| Karki R, Lee E, Place D, Samir P, Mavuluri J, Sharma BR, Balakrishnan A, Malireddi RKS, Geiger R, Zhu Q, Neale G, Kanneganti TD.
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| Cell 173(4):920-933.e13. doi: 10.1016/j.cell.2018.02.055. Epub 2018 Mar 22. 2018
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| 2 | BIRC2, BIRC3, NAIP
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| Inhibitor of apoptosis proteins, NAIP, cIAP1 and cIAP2 expression during macrophage differentiation and M1/M2 polarization.
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| Morón-Calvente V, Romero-Pinedo S, Toribio-Castelló S, Plaza-Díaz J, Abadía-Molina AC, Rojas-Barros DI, Beug ST, LaCasse EC, MacKenzie A, Korneluk R, Abadía-Molina F.
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| PLoS One 13(3):e0193643. doi: 10.1371/journal.pone.0193643. eCollection 2018.
2018
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| 3 | NAIP
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| Neuronal apoptosis inhibitory protein is implicated in amyotrophic lateral sclerosis symptoms.
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| Kano O, Tanaka K, Kanno T, Iwasaki Y, Ikeda JE.
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| Sci Rep 8(1):6. doi: 10.1038/s41598-017-18627-w.
2018
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| 4 | NAIP
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| Broad detection of bacterial type III secretion system and flagellin proteins by the human NAIP/NLRC4 inflammasome.
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| Reyes Ruiz VM, Ramirez J, Naseer N, Palacio NM, Siddarthan IJ, Yan BM, Boyer MA, Pensinger DA, Sauer JD, Shin S.
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| Proc Natl Acad Sci U S A 114(50):13242-13247. doi: 10.1073/pnas.1710433114. Epub 2017 Nov 27.
2017
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| 5 | NAIP
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| Neuronal apoptosis inhibitory protein (NAIP) localizes to the cytokinetic machinery during cell division.
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| Abadía-Molina F, Morón-Calvente V, Baird SD, Shamim F, Martín F, MacKenzie A.
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| Sci Rep 7:39981. doi: 10.1038/srep39981.
2017
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| 6 | NAIP
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| Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice.
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| Zhao Y, Shi J, Shi X, Wang Y, Wang F, Shao F.
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| J Exp Med 213(5):647-56. doi: 10.1084/jem.20160006. Epub 2016 Apr 25.
2016
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| 7 | NAIP
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| Cutting Edge: Inflammasome Activation in Primary Human Macrophages Is Dependent on Flagellin.
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| Kortmann J, Brubaker SW, Monack DM.
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| J Immunol 195(3):815-9. doi: 10.4049/jimmunol.1403100. Epub 2015 Jun 24.
2015
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| 8 | NAIP, TEAD1, YAP1
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| Interaction with the Yes-associated protein (YAP) allows TEAD1 to positively regulate NAIP expression.
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| Landin Malt A, Georges A, Silber J, Zider A, Flagiello D.
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| FEBS Lett 587(19):3216-23. doi: 10.1016/j.febslet.2013.08.013. Epub 2013 Aug 28.
2013
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| 9 | NAIP, SMA, SMA2, SMA3, SMA4, SMN1, SMN2
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| Correlation of SMN2, NAIP, p44, H4F5 and Occludin genes copy number with spinal muscular atrophy phenotype in Tunisian patients.
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| Amara A, Adala L, Ben Charfeddine I, Mamaï O, Mili A, Lazreg TB, H'mida D, Amri F, Salem N, Boughammura L, Saad A, Gribaa M.
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| Eur J Paediatr Neurol 16(2):167-74. doi: 10.1016/j.ejpn.2011.07.007. Epub 2011 Aug 6.
2012
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| 10 | APAF1, NAIP
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| Integrity of ATP binding site is essential for effective inhibition of the intrinsic apoptosis pathway by NAIP.
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| Karimpour S, Davoodi J, Ghahremani MH.
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| Biochem Biophys Res Commun 407(1):158-62. Epub 2011 Mar 1.
2011
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| 11 | NAIP, NLRC4
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| Differential requirements for NAIP5 in activation of the NLRC4 inflammasome.
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| Lightfield KL, Persson J, Trinidad NJ, Brubaker SW, Kofoed EM, Sauer JD, Dunipace EA, Warren SE, Miao EA, Vance RE.
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| Infect Immun 79(4):1606-14. Epub 2011 Jan 31.
2011
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| 12 | NAIP, NLRC4
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| The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.
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| Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, Liu L, Shao F.
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| Nature 477(7366):596-600. doi: 10.1038/nature10510.
2011
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| 13 | NAIP, NLRC4, TLR5
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| A novel pathway for inducible nitric-oxide synthase activation through inflammasomes.
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| Buzzo CL, Campopiano JC, Massis LM, Lage SL, Cassado AA, Leme-Souza R, Cunha LD, Russo M, Zamboni DS, Amarante-Mendes GP, Bortoluci KR.
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| J Biol Chem 285(42):32087-95. Epub 2010 Aug 11. 2010
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| 14 | NAIP
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| A novel protein isoform of the multicopy human NAIP gene derives from intragenic Alu SINE promoters.
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| Romanish MT, Nakamura H, Lai CB, Wang Y, Mager DL.
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| PLoS One 4(6):e5761.
2009
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| 15 | NAIP, SMN2
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| Phenotype modifiers of spinal muscular atrophy: the number of SMN2 gene copies, deletion in the NAIP gene and probably gender influence the course of the disease.
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| Jedrzejowska M, Milewski M, Zimowski J, Borkowska J, Kostera-Pruszczyk A, Sielska D, Jurek M, Hausmanowa-Petrusewicz I.
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| Acta Biochim Pol 56(1):103-8. Epub 2009 Mar 14.
2009
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| 16 | NAIP, SMN1
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| Deletion analysis of SMN1 and NAIP genes in Southern Chinese children with spinal muscular atrophy.
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| Liang YH, Chen XL, Yu ZS, Chen CY, Bi S, Mao LG, Zhou BL, Zhang XN.
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| J Zhejiang Univ Sci B 10(1):29-34.
2009
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| 17 | NAIP, SMN2
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| SMN2 and NAIP gene dosages in Vietnamese patients with spinal muscular atrophy.
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| Tran VK, Sasongko TH, Hong DD, Hoan NT, Dung VC, Lee MJ, Gunadi, Takeshima Y, Matsuo M, Nishio H.
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| Pediatr Int 50(3):346-51.PMID: 18533950 2008
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| 18 | NAIP, SMA, SMN1
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| Molecular analysis of the SMN1 and NAIP genes in Iranian patients with spinal muscular atrophy.
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| Derakhshandeh-Peykar P, Esmaili M, Ousati-Ashtiani Z, Rahmani M, Babrzadeh F, Farshidi S, Attaran E, Sajedifar MM, Farhud DD.
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| Ann Acad Med Singapore 36(11):937-41.
2007
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| 19 | NAIP
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| Functional human NAIP promoter transcription regulatory elements for the NAIP and PsiNAIP genes.
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| Xu M, Okada T, Sakai H, Miyamoto N, Yanagisawa Y, MacKenzie AE, Hadano S, Ikeda JE.
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| Biochim Biophys Acta 1574(1):35-50. 2002
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| 20 | BDP1, NAIP, CDK7, SMN1, SMN2
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| Evolutionary divergence of the mouse and human Lgn1/SMA repeat structures.
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| Growney JD, Scharf JM, Kunkel LM, Dietrich WF.
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| Genomics 64(1):62-81. 2000
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| 21 | NAIP
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| The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury.
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| Holcik M, Thompson CS, Yaraghi Z, Lefebvre CA, MacKenzie AE, Korneluk RG.
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| Proc Natl Acad Sci U S A 97(5):2286-90. 2000
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| 22 | NAIP
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| The neuronal apoptosis inhibitory protein suppresses neuronal differentiation and apoptosis in PC12 cells.
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| Gotz R, Karch C, Digby MR, Troppmair J, Rapp UR, Sendtner M.
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| Hum Mol Genet 9(17):2479-89. 2000
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| 23 | NAIP
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| Identification of two distinct transcripts for the neuronal apoptosis inhibitory protein gene.
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| Yamamoto K, Sakai H, Hadano S, Gondo Y, Ikeda JE.
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| Biochem Biophys Res Commun 264(3):998-1006 1999
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| 24 | NAIP, SMN1, SMN2, GTF2H2
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| Sequence of a 131-kb region of 5q13.1 containing the spinal muscular atrophy candidate genes SMN and NAIP.
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| Chen Q, Baird SD, Mahadevan M, Besner-Johnston A, Farahani R, Xuan J, Kang X, Lefebvre C, Ikeda JE, Korneluk RG, MacKenzie AE.
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| Genomics 48(1):121-7. 1998
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| 25 | NAIP, SMA, SMN1
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| A possible role of NAIP gene deletions in sex-related spinal muscular atrophy phenotype variation.
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| Novelli G, et al.
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| Neurogenetics 1 : 29-30. 1997
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| 26 | NAIP, SMA, SMN1
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| SMN(T) and NAIP mutations in Canadian families with spinal muscular atrophy (SMA): genotype/phenotype correlations with disease severity.
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| Simard LR, Rochette C, Semionov A, Morgan K, Vanasse M.
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| Am J Med Genet 72(1):51-8. 1997
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| 27 | NAIP, SMA, SMN1
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| Molecular analysis of survival motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP) genes of spinal muscular atrophy patients and their parents.
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| Chang JG, Jong YJ, Lin SP, Soong BW, Tsai CH, Yang TY, Chang CP, Wang WS.
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| Hum Genet 100(5-6):577-81 1997
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| 28 | NAIP, SMA, SMN1
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| De novo rearrangements found in 2% of index patients with spinal muscular atrophy: mutational mechanisms, parental origin, mutation rate, and implications for genetic counseling.
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| Wirth B, Schmidt T, Hahnen E, Rudnik-Schoneborn S, Krawczak M, Muller-Myhsok B, Schonling J, Zerres K.
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| Am J Hum Genet 61(5):1102-11. 1997
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| 29 | BIRC2, BIRC3, CD47, NAIP, XIAP
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| Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes.
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| Liston P, et al.
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| Nature 379 : 349-353. 1996
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| 30 | NAIP, SMA, SMN1, SMN2
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| Molecular analysis of SMN and NAIP genes in Spanish spinal muscular atrophy (SMA) families and correlation between number of copies of cBCD541 and SMA phenotype.
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| Velasco E, et al.
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| Hum Mol Genet 5 : 257-263. 1996
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| 31 | NAIP, SMN1
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| The mouse region syntenic for human spinal muscular atrophy lies within the Lgn1 critical interval and contains multiple copies of Naip exon 5.
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| Scharf JM, et al.
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| Genomics 38 : 405-417. 1996
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| 32 | NAIP, SMA
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| The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy.
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| Roy N, et al.
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| Cell 80 : 167-178. 1995
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