| 1 | GRIP1, MYO6, TRIP6
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| Trip6 promotes dendritic morphogenesis through dephosphorylated GRIP1-dependent myosin VI and F-actin organization.
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| Lv K, Chen L, Li Y, Li Z, Zheng P, Liu Y, Chen J, Teng J.
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| J Neurosci 35(6):2559-71. doi: 10.1523/JNEUROSCI.2125-14.2015.
2015
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| 2 | MYO6, SLC9A3
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| Myosin VI mediates the movement of NHE3 down the microvillus in intestinal epithelial cells.
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| Chen T, Hubbard A, Murtazina R, Price J, Yang J, Cha B, Sarker R, Donowitz M.
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| J Cell Sci 127(Pt 16):3535-45. doi: 10.1242/jcs.149930. Epub 2014 Jun 13.
2014
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| 3 | DFNA22, MYO6
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| Progressive hereditary hearing impairment caused by a MYO6 mutation resembles presbyacusis.
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| Oonk AM, Leijendeckers JM, Lammers EM, Weegerink NJ, Oostrik J, Beynon AJ, Huygen PL, Kunst HP, Kremer H, Snik AF, Pennings RJ.
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| Hear Res 299:88-98. doi: 10.1016/j.heares.2012.12.015. Epub 2013 Jan 20.
2013
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| 4 | DAB2, GIPC1, MYO6, TFAP2A
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| Myosin VI and Associated Proteins Are Expressed in Human Macrophages but Do Not Play a Role in Foam Cell Formation in THP-1 Cells.
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| Dawson HJ, Hibbert AP, Chantler PD, Botham KM.
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| Int J Vasc Med 2013:516015. doi: 10.1155/2013/516015. Epub 2013 Jun 9.
2013
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| 5 | DOCK7, MYO6
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| Dock7: a GEF for Rho-family GTPases and a novel myosin VI-binding partner in neuronal PC12 cells.
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| Majewski Ł, Sobczak M, Havrylov S, Jóźwiak J, Rędowicz MJ.
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| Biochem Cell Biol 90(4):565-74. doi: 10.1139/o2012-009. Epub 2012 Apr 4.
2012
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| 6 | MYO6
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| Myosin VI is required for maintenance of brush border structure, composition, and membrane trafficking functions in the intestinal epithelial cell.
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| Hegan PS, Giral H, Levi M, Mooseker MS.
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| Cytoskeleton (Hoboken) 69(4):235-51. doi: 10.1002/cm.21018. Epub 2012 Mar 2.
2012
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| 7 | GIPC1, MYO6, VANGL2
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| Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear.
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| Giese AP, Ezan J, Wang L, Lasvaux L, Lembo F, Mazzocco C, Richard E, Reboul J, Borg JP, Kelley MW, Sans N, Brigande J, Montcouquiol M.
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| Development 139(20):3775-85.
2012
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| 8 | MYO6, OPTN
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| Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane.
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| Bond LM, Peden AA, Kendrick-Jones J, Sellers JR, Buss F.
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| Mol Biol Cell 22(1):54-65. Epub 2010 Dec 9.
2011
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| 9 | MYO6
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| Altered renal proximal tubular endocytosis and histology in mice lacking myosin-VI.
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| Gotoh N, Yan Q, Du Z, Biemesderfer D, Kashgarian M, Mooseker MS, Wang T.
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| Cytoskeleton (Hoboken) 67(3):178-92. doi: 10.1002/cm.20435.
2010
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| 10 | DFNA22, MYO6
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| Genotype-phenotype correlation for DFNA22: characterization of non-syndromic, autosomal dominant, progressive sensorineural hearing loss due to MYO6 mutations.
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| Topsakal V, Hilgert N, van Dinther J, Tranebjaerg L, Rendtorff ND, Zarowski A, Offeciers E, Van Camp G, van de Heyning P.
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| Audiol Neurootol 15(4):211-20. doi: 10.1159/000255339. Epub 2009 Nov 5.
2010
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| 11 | MYO6, OTOF
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| Otoferlin interacts with myosin VI: implications for maintenance of the basolateral synaptic structure of the inner hair cell.
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| Heidrych P, Zimmermann U, Kuhn S, Franz C, Engel J, Duncker SV, Hirt B, Pusch CM, Ruth P, Pfister M, Marcotti W, Blin N, Knipper M.
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| Hum Mol Genet 18(15):2779-90. Epub 2009 May 5.
2009
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| 12 | MYO6
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| Myosin VI is required for the proper maturation and function of inner hair cell ribbon synapses.
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| Roux I, Hosie S, Johnson SL, Bahloul A, Cayet N, Nouaille S, Kros CJ, Petit C, Safieddine S.
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| Hum Mol Genet 18(23):4615-28. doi: 10.1093/hmg/ddp429. Epub 2009 Sep 10.
2009
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| 13 | MYO6, DFNA22
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| A novel nonsense mutation in MYO6 is associated with progressive nonsyndromic hearing loss in a Danish DFNA22 family.
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| Sanggaard KM, Kjaer KW, Eiberg H, NŸrnberg G, NŸrnberg P, Hoffman K, Jensen H, S¿rum C, Rendtorff ND, Tranebjaerg L.
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| Am J Med Genet A 146A(8):1017-25. 2008
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| 14 | MYO6, DFNA22
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| A splice-site mutation and overexpression of MYO6 cause a similar phenotype in two families with autosomal dominant hearing loss.
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| Hilgert N, Topsakal V, van Dinther J, Offeciers E, Van de Heyning P, Van Camp G.
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| Eur J Hum Genet 16(5):593-602. Epub 2008 Jan 23. 2008
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| 15 | MYO6, PTPRQ
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| Dynamic compartmentalization of protein tyrosine phosphatase receptor Q at the proximal end of stereocilia: implication of myosin VI-based transport.
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| Sakaguchi H, Tokita J, Naoz M, Bowen-Pope D, Gov NS, Kachar B.
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| Cell Motil Cytoskeleton 65(7):528-38.PMID: 18412156 2008
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| 16 | LMTK2, MYO6
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| BREK/LMTK2 is a myosin VI-binding protein involved in endosomal membrane trafficking.
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| Inoue T, Kon T, Ohkura R, Yamakawa H, Ohara O, Yokota J, Sutoh K.
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| Genes Cells 13(5):483-95.PMID: 18429820 2008
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| 17 | MYO6
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| A Myo6 mutation destroys coordination between the myosin heads, revealing new functions of myosin VI in the stereocilia of mammalian inner ear hair cells.
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| Hertzano R, Shalit E, Rzadzinska AK, Dror AA, Song L, Ron U, Tan JT, Shitrit AS, Fuchs H, Hasson T, Ben-Tal N, Sweeney HL, de Angelis MH, Steel KP, Avraham KB.
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| PLoS Genet 4(10):e1000207. doi: 10.1371/journal.pgen.1000207.
2008
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| 18 | CALCOCO2, MYO6, TAX1BP1
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| T6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion.
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| Morriswood B, Ryzhakov G, Puri C, Arden SD, Roberts R, Dendrou C, Kendrick-Jones J, Buss F.
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| J Cell Sci 120(Pt 15):2574-85. Epub 2007 Jul 17.
2007
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| 19 | MYO6
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| Myosin VI is required for targeted membrane transport during cytokinesis.
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| Arden SD, Puri C, Au JS, Kendrick-Jones J, Buss F.
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| Mol Biol Cell 18(12):4750-61. Epub 2007 Sep 19.PMID: 17881731 2007
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| 20 | LRP2, GIPC1, MYO6
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| Binding of internalized receptors to the PDZ domain of GIPC/synectin recruits myosin VI to endocytic vesicles.
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| Naccache SN, Hasson T, Horowitz A.
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| Proc Natl Acad Sci U S A 103(34):12735-40. Epub 2006 Aug 14. 2006
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| 21 | FHCD, MYO6
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| Novel association of hypertrophic cardiomyopathy, sensorineural deafness, and a mutation in unconventional myosin VI (MYO6).
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| Mohiddin SA, Ahmed ZM, Griffith AJ, Tripodi D, Friedman TB, Fananapazir L, Morell RJ.
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| J Med Genet 41(4):309-14. No abstract available. 2004
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| 22 | MYO6, DFNA22
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| Human deafness mutation of myosin VI (C442Y) accelerates the ADP dissociation rate.
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| Sato O, White HD, Inoue A, Belknap B, Ikebe R, Ikebe M.
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| J Biol Chem 279(28):28844-54. Epub 2004 Apr 29. 2004
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| 23 | DFNB37, MYO6
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| Mutations of MYO6 are associated with recessive deafness, DFNB37.
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| Ahmed ZM, Morell RJ, Riazuddin S, Gropman A, Shaukat S, Ahmad MM, Mohiddin SA, Fananapazir L, Caruso RC, Husnain T, Khan SN, Riazuddin S, Griffith AJ, Friedman TB, Wilcox ER.
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| Am J Hum Genet 72(5):1315-22. Epub 2003 Apr 08. 2003
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| 24 | MYO6
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| Myo6 facilitates the translocation of endocytic vesicles from cell peripheries.
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| Aschenbrenner L, Lee T, Hasson T.
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| Mol Biol Cell 14(7):2728-43. Epub 2003 Mar 20. 2003
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| 25 | DFNA22, MYO6
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| MYO6, the human homologue of the gene responsible for deafness in Snell's waltzer mice, is mutated in autosomal dominant nonsyndromic hearing loss.
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| Melchionda S, Ahituv N, Bisceglia L, Sobe T, Glaser F, Rabionet R, Arbones ML, Notarangelo A, Di Iorio E, Carella M, Zelante L, Estivill X, Avraham KB, Gasparini P.
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| Am J Hum Genet 69(3):635-40. 2001
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| 26 | MYO6
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| Novel myosin VI isoform is abundantly expressed in retina.
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| Breckler J, Au K, Cheng J, Hasson T, Burnside B.
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| Exp Eye Res 70(1):121-34. 2000
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| 27 | MYO6
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| Genomic structure of the human unconventional myosin VI gene.
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| Ahituv N, Sobe T, Robertson NG, Morton CC, Taggart RT, Avraham KB.
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| Gene 261(2):269-75. 2000
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| 28 | GLC1A, MYO6
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| Analysis of myocilin mutations in 1703 glaucoma patients from five different populations.
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| Fingert JH, et al.
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| Hum Mol Genet 8(5):899-905. 1999
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| 29 | MYO6
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| Myosin VI is an actin-based motor that moves backwards.
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| Wells AL, et al.
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| Nature 401(6752):505-8 1999
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| 30 | MYO6
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| Characterization of unconventional MYO6, the human homologue of the gene responsible for deafness in Snell's waltzer mice.
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| Avraham KB, Hasson T, Sobe T, Balsara B, Testa JR, Skvorak AB, Morton CC, Copeland NG, Jenkins NA.
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| Hum Mol Genet 6(8):1225-31. 1997
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| 31 | ADAMTS3, AKAP6, ALMS1, ANKRD28, AREL1, ARHGEF10, ARHGEF11, ARHGEF17, ARNT2, BAZ2A, CABIN1, CAST, CHD9, CIC, CLEC16A, CLOCK, CTNND1, DCLK1, DDX46, DIDO1, DNAH9, DNM3, DOCK3, DYNC1H1, ECM29, ENTPD4, EPB41L1, EZH1, FAM65B, FRMPD4, GCC2, HECW1, HERC2, HISPPD1, HUWE1, IGSF1, KAT6B, KIAA0319, KIAA0323, KIAA0355, KIAA0379, KIF3B, KMT2B, LBA1, MADD, MAST4, MCF2L, MDN1, MTMR3, MYO6, N4BP3, NACAD, NRCAM, PCDH9, PCDHGA8, PCDHGC3, PDZD2, PER2, PFAS, PLEKHM1, PLXNB2, PRORP, PRUNE2, PTPRN2, RAPGEF2, RIMBP2, RIMS1, RUSC2, SALL2, SEC16A, SEMA3C, SEMA3E, SETD1A, SFRS14, SNPH, SPECC1L, SPTBN2, SR140, SRCAP, SRRM2, SYNJ2, TECPR2, TLN2, TRIM66, TTC37, UBR2, WNK1, XPO6, ZBTB39, ZBTB5, ZFYVE16, ZFYVE26, ZMYM3, ZNF518A, ZNF609, ZNF629, ZNF646
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| Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
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| Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A,Kotani H, Nomura N, Ohara O.
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| DNA Res 4(2):141-50. 1997
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