| 1 | MYH6
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| Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy.
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| Jiang J, Wakimoto H, Seidman JG, Seidman CE.
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| Science 342(6154):111-4. doi: 10.1126/science.1236921.
2013
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| 2 | MYBPC3, MYH6, MYH7
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| Poor prognosis of rare sarcomeric gene variants in patients with dilated cardiomyopathy.
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| Merlo M, Sinagra G, Carniel E, Slavov D, Zhu X, Barbati G, Spezzacatene A, Ramani F, Salcedo E, Di Lenarda A, Mestroni L, Taylor MR; Familial Cardiomyopathy Registry.
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| Clin Transl Sci 6(6):424-8. doi: 10.1111/cts.12116. Epub 2013 Oct 3.
2013
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| 3 | MYH6, MYH7, MYH7B
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| Cardiac myosin activation: a potential therapeutic approach for systolic heart failure.
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| Malik FI, Hartman JJ, Elias KA, Morgan BP, Rodriguez H, Brejc K, Anderson RL, Sueoka SH, Lee KH, Finer JT, Sakowicz R, Baliga R, Cox DR, Garard M, Godinez G, Kawas R, Kraynack E, Lenzi D, Lu PP, Muci A, Niu C, Qian X, Pierce DW, Pokrovskii M, Suehiro I, Sylvester S, Tochimoto T, Valdez C, Wang W, Katori T, Kass DA, Shen YT, Vatner SF, Morgans DJ.
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| Science 331(6023):1439-43.
2011
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| 4 | MYH6, SSS3
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| A rare variant in MYH6 is associated with high risk of sick sinus syndrome.
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| Holm H, Gudbjartsson DF, Sulem P, Masson G, Helgadottir HT, Zanon C, Magnusson OT, Helgason A, Saemundsdottir J, Gylfason A, Stefansdottir H, Gretarsdottir S, Matthiasson SE, Thorgeirsson GM, Jonasdottir A, Sigurdsson A, Stefansson H, Werge T, Rafnar T, Kiemeney LA, Parvez B, Muhammad R, Roden DM, Darbar D, Thorleifsson G, Walters GB, Kong A, Thorsteinsdottir U, Arnar DO, Stefansson K.
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| Nat Genet 43(4):316-20.
2011
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| 5 | ASD3, MYH6
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| Cardiac alpha-myosin (MYH6) is the predominant sarcomeric disease gene for familial atrial septal defects.
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| Posch MG, Waldmuller S, Müller M, Scheffold T, Fournier D, Andrade-Navarro MA, De Geeter B, Guillaumont S, Dauphin C, Yousseff D, Schmitt KR, Perrot A, Berger F, Hetzer R, Bouvagnet P, Özcelik C.
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| PLoS One 6(12):e28872. doi: 10.1371/journal.pone.0028872. Epub 2011 Dec 14.
2011
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| 6 | ASD3, MYH6
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| Alpha-cardiac myosin heavy chain (MYH6) mutations affecting myofibril formation are associated with congenital heart defects.
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| Granados-Riveron JT, Ghosh TK, Pope M, Bu'Lock F, Thornborough C, Eason J, Kirk EP, Fatkin D, Feneley MP, Harvey RP, Armour JA, David Brook J.
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| Hum Mol Genet 19(20):4007-16. Epub 2010 Jul 23.
2010
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| 7 | MEF2C, MYH6, TBX5
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| Physical interaction between TBX5 and MEF2C is required for early heart development.
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| Ghosh TK, Song FF, Packham EA, Buxton S, Robinson TE, Ronksley J, Self T, Bonser AJ, Brook JD.
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| Mol Cell Biol 29(8):2205-18. Epub 2009 Feb 9.
2009
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| 8 | ASD2, ASD3, GATA4, ICHD, JAG1, MYH6, NKX2-5, NOTCH1, TBX1, TBX20, TBX5, TFAP2B, THRAP2
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| The developmental genetics of congenital heart disease.
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| Bruneau BG.
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| Nature 451(7181):943-8. 2008
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| 9 | ACTA2, ACTC1, ASD3, ASD5, CMD1R, CMD1S, CMH1, CMH6, CMHNE, MYBPC3, MYH11, MYH6, MYH7, TAAD1, TAAD4
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| Mutations in sarcomeric protein genes not only lead to cardiomyopathy but also to congenital cardiovascular malformations.
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| Wessels MW, Willems PJ.
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| Clin Genet 74(1):16-9. Epub 2008 Apr 8. 2008
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| 10 | MYH6
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| Long single alpha-helical tail domains bridge the gap between structure and function of myosin VI.
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| Spink BJ, Sivaramakrishnan S, Lipfert J, Doniach S, Spudich JA.
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| Nat Struct Mol Biol 15(6):591-7. Epub 2008 May 30.
2008
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| 11 | ASD3, MYH6
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| Mutation in myosin heavy chain 6 causes atrial septal defect.
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| Ching YH, Ghosh TK, Cross SJ, Packham EA, Honeyman L, Loughna S, Robinson TE, Dearlove AM, Ribas G, Bonser AJ, Thomas NR, Scotter AJ, Caves LS, Tyrrell GP, Newbury-Ecob RA, Munnich A, Bonnet D, Brook JD.
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| Nat Genet 37(4):423-8. Epub 2005 Feb 27. 2005
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| 12 | MYH6, ASD3
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| A new mutation linked to atrial septal defect.
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| Stein R.
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| Clin Genet 68(2):114-116. No abstract available. 2005
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| 13 | CMD1EE, MYH6
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| Alpha-myosin heavy chain: a sarcomeric gene associated with dilated and hypertrophic phenotypes of cardiomyopathy.
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| Carniel E, Taylor MR, Sinagra G, Di Lenarda A, Ku L, Fain PR, Boucek MM, Cavanaugh J, Miocic S, Slavov D, Graw SL, Feiger J, Zhu XZ, Dao D, Ferguson DA, Bristow MR, Mestroni L.
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| Circulation 112(1):54-9.
2005
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| 14 | MYH6, PLN, CMH6, CMD1W
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| Molecular genetics and genomics of heart failure.
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| Liew CC, Dzau VJ.
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| Nat Rev Genet 5(11):811-25. 2004
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| 15 | MYH6, PRKAG2
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| Identification of a gene responsible for familial Wolff-Parkinson-White syndrome.
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| Gollob MH, Green MS, Tang AS, Gollob T, Karibe A, Ali Hassan AS, Ahmad F, Lozado R, Shah G, Fananapazir L, Bachinski LL, Roberts R, Hassan AS.
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| N Engl J Med 344(24):1823-31. 2001
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| 16 | MYH6
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| A molecular basis for Wolff-Parkinson-White syndrome.
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| Basson CT.
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| N Engl J Med 344(24):1861-4. No abstract available. 2001
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| 17 | MYH6
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| A trinucleotide repeat combination polymorphism in the cardiac alpha myosin heavy chain (MYH6) gene.
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| Van den Berg MH, et al.
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| Hum Genet 95 : 723-724. 1995
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| 18 | MYH6
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| Structural organization of the human cardiac alpha-myosin heavy chain gene (MYH6).
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| Epp TA, et al.
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| Genomics 18 : 505-509. 1993
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| 19 | MYH6
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| Dinucleotide repeat polymorphism at the human gene for cardiac beta-myosin heavy chain (MYH6).
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| Fougerousse F, et al.
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| Hum Mol Genet 1 : 64. 1992
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| 20 | CMH1, MYH6
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| Detection of a new mutation in the beta-myosin heavy chain gene in an individual with hypertrophic cardiomyopathy.
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| Marian AJ, et al.
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| J Clin Invest 90 : 2156-2165. 1992
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| 21 | MYH6, MYH7
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| Molecular cloning and chromosomal localization of a gene coding for human cardiac myosin heavy-chain.
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| Matsuoka R, et al.
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| Jpn Circ J 54 : 1206-1213. 1990
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| 22 | CMH1, MYH6
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| A locus for familial hypertrophic cardiomyopathy is closely linked to the cardiac myosin heavy chain genes, CRI-L436, and CRI-L329 on chromosome 14 at q11-q12.
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| Solomon SD, et al.
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| Am J Hum Genet 47 : 389-394. 1990
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| 23 | MYH6, MYH7
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| Human cardiac myosin heavy chain gene mapped within chromosome region 14q11.2-q13.
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| Matsuoka R, et al.
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| Am J Med Genet 32 : 279-284. 1989
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| 24 | MYH6, MYH7
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| Human cardiac myosin heavy chain genes and their linkage in the genome.
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| Saez LJ, et al.
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| Nucleic Acids Res 15 : 5443-5459. 1987
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